公开(公告)号：US20120010697A1

公开(公告)日：2012-01-12

申请号：US13176398

申请日：2011-07-05

申请人： Kyong-Min SHIN ,  Kang Sun Hong ,  Eun Ae Jo ,  Yong-Jin Kim ,  Cheul Lee ,  Sam Sea Oh ,  Chang-Ha Lee ,  Hong-Gook Lim

发明人： Kyong-Min SHIN ,  Kang Sun Hong ,  Eun Ae Jo ,  Yong-Jin Kim ,  Cheul Lee ,  Sam Sea Oh ,  Chang-Ha Lee ,  Hong-Gook Lim

IPC分类号： A61F2/24 ,  B23P11/00

CPC分类号： A61F2/2415 ,  A61F2/2418 ,  A61F2220/0075 ,  Y10T29/49826

摘要： A heart valve prosthesis and a method of fabricating the same. The heart valve prosthesis uses a leaflet of pig pericardium or a leaflet of cattle pericardium, which has a suitable thickness according to the size of the valve, and a stent. The heart valve prosthesis is fabricated by placing a valve body over a Dacron body, binding the valve body to the Dacron body using stitching fiber, rolling the Dacron body into a cylindrical form such that the valve body is located inside, binding opposite edges of the Dacron body to each other using stitching fiber, and inserting the resultant structure into a stent, which is knitted using a shape memory alloy wire. The heart valve prosthesis is friendly to and is not rejected by human tissue, is free from deformation, and can be implanted using a non-invasive manner without incising the chest wall of a patient.

摘要翻译： 一种心脏瓣膜假体及其制造方法。 心脏瓣膜假体使用猪心包的小叶或牛心包的小叶，其根据瓣膜的尺寸具有合适的厚度和支架。 心脏瓣膜假体是通过将阀体放置在达克龙体上而制成的，其使用缝合纤维将阀体与达克龙体结合，将达克龙体旋转成圆柱形，使得阀体位于内部， 使用缝合纤维彼此使用涤纶体，并将所得到的结构插入到使用形状记忆合金丝编织的支架中。 心脏瓣膜假体对人体组织是友好的并且不被人体组织排斥，没有变形，并且可以非侵入性地植入，而不会切开患者的胸壁。

公开(公告)号：US20110098825A1

公开(公告)日：2011-04-28

申请号：US12892586

申请日：2010-09-28

申请人： Kyong-Min SHIN ,  Jeung-Hee Nam ,  Kang-Sun Hong ,  Ho-Young Song ,  Tae-Hyung Kim

发明人： Kyong-Min SHIN ,  Jeung-Hee Nam ,  Kang-Sun Hong ,  Ho-Young Song ,  Tae-Hyung Kim

IPC分类号： A61F2/04

CPC分类号： A61F2/90 ,  A61F2/885 ,  A61F2002/047 ,  A61F2002/075 ,  A61F2002/8483 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2220/0008

摘要： Disclosed herein is a stent for prostatic urethra expansion which does not generate bladder stones, is removable without causing injury on a urethra, and does not generate atrophy of a prostatic urethra even after removal. The stent for prostatic urethra expansion include a stent unit including a cylindrical body with space parts formed by knotting or crossing shape memory alloy wires and bending terminals formed at both ends of the cylindrical body, a pair of hook wires passing through the space parts and knotted to the shape memory alloy wires, both ends thereof being wound on the bending terminals and then being bent upwardly to produce hooks, and a pair of hanging strings arranged in opposite directions to form a hanging knot. The stent for prostatic urethra expansion does not move into the bladder, and expands and maintains a lumen of the stenosed prostatic urethra, thereby reducing post-operative recovery time.

摘要翻译： 本文公开了一种前列腺尿道扩张支架，其不产生膀胱结石，可移除而不在尿道上造成损伤，即使在移除后也不会产生前列腺尿道的萎缩。 用于前列腺尿道扩张的支架包括支架单元，其包括圆柱体，其具有通过打结或交叉形状记忆合金线形成的空间部分和形成在圆柱体两端的弯曲端子，穿过空间部分并打结的一对钩线 对形状记忆合金线，其两端卷绕在弯曲端子上，然后向上弯曲以产生钩状物，以及一对悬挂绳，以相反方向布置以形成悬挂结。 用于前列腺尿道扩张的支架不会移动到膀胱中，并扩张并保持狭窄的前列腺尿道的内腔，从而减少术后恢复时间。

公开(公告)号：US20100256732A1

公开(公告)日：2010-10-07

申请号：US12577871

申请日：2009-10-13

申请人： Kyong-Min SHIN ,  Byung Cheol Myung

发明人： Kyong-Min SHIN ,  Byung Cheol Myung

IPC分类号： A61F2/86 ,  A61F2/82 ,  B23P17/00

CPC分类号： A61F2/90 ,  A61F2210/0076 ,  A61F2230/0078 ,  A61F2250/0018 ,  A61F2250/0039 ,  Y10T29/4998

摘要： A wavily deformable stent includes a hollow cylindrical net body formed of elastically deformable wires interlaced with each other. The net body extends in a longitudinal direction and terminates at open opposite ends. The net body has at least one high-rigidity section and at least one low-rigidity section less rigid than the high-rigidity section. The high-rigidity section and the low-rigidity section are arranged continuously and alternately along the longitudinal direction. The stent is wavily deformed and held in place against unwanted displacement when situated inside a stenosed part of a bodily organ. Also provided is a method for producing the wavily deformable stent.

摘要翻译： 波状可变形支架包括由彼此交错的可弹性变形的线形成的中空圆柱形网体。 网体在纵向方向上延伸并终止于开放的相对端。 网体具有至少一个高刚性部分和至少一个刚性高于刚性部分的刚性低的部分。 高刚性部和低刚性部沿着长度方向连续且交替地配置。 当位于身体器官狭窄部位的内部时，支架会变形并保持在适当的位置。 还提供了一种用于制造波状可变形支架的方法。

公开(公告)号：US20100211157A1

公开(公告)日：2010-08-19

申请号：US12577963

申请日：2009-10-13

申请人： Kyong-Min SHIN ,  Byung Cheol Myung ,  Yong-Hyunl Won ,  Tae-won Kim

发明人： Kyong-Min SHIN ,  Byung Cheol Myung ,  Yong-Hyunl Won ,  Tae-won Kim

IPC分类号： A61F2/06

CPC分类号： A61F2/90 ,  A61F2210/0004 ,  A61F2250/0031

摘要： A partially biodegradable stent includes a main net body of hollow cylindrical shape formed of elastically deformable wires interlaced with each other, the net body extending in a longitudinal direction and terminating at open opposite ends, and an auxiliary net portion provided at one of the open opposite ends of the main net body, the auxiliary net portion formed of a biodegradable wire which can be degraded and removed by a bodily fluid. The auxiliary net portion is formed by interlacing the biodegradable wire into a cylindrical shape independently of the main net body or by interlacing the biodegradable wire with the elastically deformable wires at one of the open opposite ends of the main net body.

摘要翻译： 部分可生物降解的支架包括由互相交错的可弹性变形的线形成的中空圆柱形的主网体，网体沿纵向方向延伸并且在相对的开放端处终止，辅助网部设置在开放的相对的一个 主网体的端部，辅助网部由可由体液降解和去除的可生物降解的线形成。 辅助网部分通过将生物可降解的线交织成独立于主网体的圆柱形形状，或者通过将可生物降解的线与可互换的可变形的线交织在主网体的开放的相对端之一处而形成。

公开(公告)号：US20130012969A1

公开(公告)日：2013-01-10

申请号：US13542412

申请日：2012-07-05

申请人： Kyong-Min SHIN

发明人： Kyong-Min SHIN

IPC分类号： A61B17/11

CPC分类号： A61F2/064 ,  A61B17/11 ,  A61B17/1114 ,  A61B2017/00862 ,  A61B2017/00867 ,  A61B2017/00995 ,  A61B2017/1139 ,  A61F2/90

摘要： Disclosed herein is a stent for connecting adjacent tissues of the organs of a patient. The stent includes a hollow cylindrical body which is formed by weaving a superelastic shape-memory alloy wire in an overlapping manner such that rhombic openings are formed, and wing parts which are provided by expanding respective opposite ends of the hollow cylindrical body outwards and turning the opposite ends inside out on bent portions. The wing parts face each other so that the wing parts are tensed in a longitudinal direction of the cylindrical body. Thereby, the wing parts can elastically move inwards or outwards with respect to the longitudinal direction to automatically adjust a distance between the wing parts in response to the distance between the adjacent tissues of the organs or thicknesses of walls of the organs, so that the wing parts are put into close contact with the adjacent tissues.

摘要翻译： 本文公开了一种用于连接患者器官的相邻组织的支架。 支架包括中空圆柱体，其通过以重叠的方式编织超弹性形状记忆合金线而形成，使得形成菱形开口，以及翼部，其通过将中空圆柱体的相应的相对端向外扩展并将 弯曲部分的内侧的相对端部。 翼部彼此面对，使得翼部在圆柱体的纵向方向上被拉紧。 因此，翼部件能够相对于纵向方向弹性地向内或向外移动，以响应于器官的相邻组织之间的距离或器官的壁的厚度来自动调整翼部之间的距离，使得翼 零件与相邻的纸巾紧密接触。

公开(公告)号：US20120316127A1

公开(公告)日：2012-12-13

申请号：US13491145

申请日：2012-06-07

申请人： Kyong-Min SHIN ,  Kun Na

发明人： Kyong-Min SHIN ,  Kun Na

IPC分类号： A61K31/7068 ,  A61P35/00 ,  B05D5/00

CPC分类号： A61L31/16 ,  A61L31/10 ,  A61L2300/416 ,  A61L2300/608 ,  A61L2420/02 ,  C08L75/04 ,  C08L27/18

摘要： This invention relates to a method of manufacturing a coating agent for a drug releasing stent and to a coating agent for a drug releasing stent manufactured thereby. This method includes (1) dissolving polyurethane in tetrahydrofuran, (2) dissolving pluronic F-127 in tetrahydrofuran, (3) dissolving a gemcitabine compound in ethanol, (4) mixing these three solutions obtained in (1) to (3) thus preparing a solution mixture, (5) applying the solution mixture obtained in (4) on a stent coated with a Teflon film, (6) drying the stent of (5) for a predetermined period of time and then immersing the stent in a polyurethane solution in tetrahydrofuran, and (7) removing the stent immersed in (6) from the polyurethane solution and then drying the stent, so that the rate of release of an anti-cancer drug applied on the stent can be continuously and maximally improved thereby maximizing anti-cancer efficacy.

摘要翻译： 本发明涉及一种制造药物释放支架用涂布剂的方法及其制造的药物释放支架用涂布剂。 该方法包括（1）将聚氨酯溶于四氢呋喃中，（2）将普鲁尼克F-127溶解在四氢呋喃中，（3）将吉西他滨化合物溶于乙醇中，（4）将（1）至（3）中得到的三种溶液混合， 溶液混合物，（5）将（4）中得到的溶液混合物涂布在涂有特氟龙膜的支架上，（6）将（5）的支架干燥规定时间，然后将支架浸渍在聚氨酯溶液 在四氢呋喃中，和（7）从聚氨酯溶液中取出浸没在（6）中的支架，然后干燥支架，使得施加在支架上的抗癌药物的释放速率可以连续和最大程度地提高，从而最大化抗 - 功效

公开(公告)号：US20160158037A1

公开(公告)日：2016-06-09

申请号：US15044892

申请日：2016-02-16

申请人： Kyong-Min SHIN ,  TAEWOONG MEDICAL CO., LTD.

发明人： Kyong-Min SHIN ,  Jeung-Hee NAM

IPC分类号： A61F2/89 ,  A61F2/04 ,  A61F2/90

CPC分类号： A61F2/89 ,  A61F2/04 ,  A61F2/852 ,  A61F2/90 ,  A61F2002/041 ,  A61F2002/043 ,  A61F2210/0004 ,  A61F2220/0025 ,  A61F2230/0006 ,  A61F2230/0019 ,  A61F2230/0069 ,  A61F2250/0039

摘要： A biodegradable double stent is used for various organs such as a biliary tract, an esophagus, an airway and a ureter. A biodegradable stent having a hollow cylindrical body woven out of a separate wire made of biodegradable polymer so as to have a plurality of rhombic spaces is fixed to an intermediate portion of a primary stent having a cylindrical body. When administered into the organ, the biodegradable stent has its original function of expanding the organ, and is firmly supported in the inner wall of a narrowed passage of the organ by pressurizing the inner wall of the narrowed passage of the organ. After a predetermined time period has elapsed, the biodegradable stent is gradually degraded away by bodily fluids, thereby enabling the primary stent to be easily removed from the organ.

公开(公告)号：US20110282429A1

公开(公告)日：2011-11-17

申请号：US13095452

申请日：2011-04-27

申请人： Kyong-Min SHIN ,  Byung-Cheol Myung

发明人： Kyong-Min SHIN ,  Byung-Cheol Myung

IPC分类号： A61F2/82

CPC分类号： A61F2/04 ,  A61F2/94 ,  A61F2/95 ,  A61F2002/041 ,  A61F2002/9505

摘要： Disclosed herein are a plastic stent and a stent operation apparatus for plastic stents. The plastic stent includes a stent body with a flow hole formed through the stent body in the longitudinal direction thereof. The stent operation apparatus includes a stent push rod having an externally threaded end. The stent body has an internal thread on the circumferential inner surface of the flow hole so that the internal thread engages with the externally threaded end of the stent push rod of the stent operation apparatus. The plastic stent is coupled to the stent push rod by the threaded engagement between the externally threaded end and the internal thread, is inserted into the body of a patient, is adjusted in location by pushing or pulling the stent push rod, and is released from the stent push rod at a correct location in the body of the patient by disengaging the threaded engagement.

摘要翻译： 本文公开了一种用于塑料支架的塑料支架和支架操作装置。 塑料支架包括具有在其长度方向上穿过支架主体形成的流动孔的支架体。 支架操作装置包括具有外螺纹端的支架推杆。 支架主体在流动孔的周向内表面上具有内螺纹，使得内螺纹与支架操作装置的支架推杆的外螺纹端接合。 塑料支架通过外螺纹端和内螺纹之间的螺纹接合被连接到支架推杆，插入到患者体内，通过推动或拉动支架推杆来调节位置，并从 支架推杆在患者身体的正确位置脱离接合线。

公开(公告)号：US20110069518A1

公开(公告)日：2011-03-24

申请号：US12730713

申请日：2010-03-24

申请人： Kyong-Min SHIN ,  Hong-chea Jung ,  Young-Jin Choi ,  Jun-hyok Lee ,  Jae-Bok Kim ,  Guk-joo Na ,  Kye-joo Kim

发明人： Kyong-Min SHIN ,  Hong-chea Jung ,  Young-Jin Choi ,  Jun-hyok Lee ,  Jae-Bok Kim ,  Guk-joo Na ,  Kye-joo Kim

IPC分类号： H02M7/02

CPC分类号： H02M7/538 ,  H02M2007/4815 ,  Y02B70/1441

摘要： Disclosed herein is the resonant inverter of a radio frequency (RF) generator for radiofrequency ablation (RFA). The resonant inverter of RF generator for RFA amplifies to high power an oscillation frequency output from an oscillator and provides the amplified oscillation frequency to an electrode. The resonant inverter processes the oscillation frequency output from the oscillator as a high-power sine wave having a frequency of 480 kHz and a Root Mean Square (RMS) power of 30 to 200 watts, and transfers the high-power sine wave to the electrode.

摘要翻译： 这里公开了用于射频消融（RFA）的射频（RF）发生器的谐振逆变器。 用于RFA的RF发生器的谐振逆变器将从振荡器输出的振荡频率放大到高功率，并将放大的振荡频率提供给电极。 谐振逆变器将振荡器输出的振荡频率作为频率为480kHz，均方根（RMS）功率为30〜200瓦特的高功率正弦波进行处理，并将高功率正弦波传送到电极 。

公开(公告)号：US20110022151A1

公开(公告)日：2011-01-27

申请号：US12898815

申请日：2010-10-06

申请人： Kyong-Min SHIN ,  Dong-Il Gwon

发明人： Kyong-Min SHIN ,  Dong-Il Gwon

IPC分类号： A61F2/82

CPC分类号： A61F2/04 ,  A61F2/852 ,  A61F2002/041 ,  A61F2230/0067 ,  A61F2250/0039

摘要： If smooth transportation of bile toward the duodenum is difficult due to cancerous cells growing in the bile duct or due to stricture of the bile duct, a cylindrical stent may be implanted into the stenosed site of the bile duct to enable smooth supply of bile. Conventional stents have no risk of slippage at an implanted position thereof, but suffer from invasively growing cancerous cells. Although a covered stent having a coating has been proposed to solve invasion of the growing cancerous cells, the covered stent may have a risk of slippage at an implanted position thereof and also, may cause pancreatitis and cholelithiasis. To solve the above described problems, disclosed herein is a stent to prevent backflow of food from the duodenum to the bile duct while assuring smooth transportation of bile without a risk of unwanted displacement caused by the transported bile. The stent includes a cylindrical outer stent, and a downwardly tapered inner stent covered with a polytetrafluoroethylene (PTFE) or silicone coating having biocompatibility. The inner and outer stents are coupled to each other to define a double structure.

摘要翻译： 如果胆汁向十二指肠顺利运输是困难的，因为胆管内生长的癌细胞或胆管狭窄，可以将圆柱形支架植入胆管狭窄部位，以使胆汁平稳供应。 常规的支架在其植入位置没有滑动的风险，但遭受侵袭性生长的癌细胞。 虽然已经提出了具有涂层的覆盖支架来解决生长中的癌细胞的侵袭，但是所覆盖的支架可能在其植入位置处具有滑动的风险，并且还可能引起胰腺炎和胆石病。 为了解决上述问题，本文公开了一种用于防止食物从十二指肠向胆管回流的支架，同时确保胆汁的平稳运输，而不会由于运输的胆汁引起不希望的位移。 支架包括圆柱形外支架和用聚四氟乙烯（PTFE）或具有生物相容性的硅氧烷涂层覆盖的向下锥形内支架。 内支架和外支架彼此连接以限定双重结构。