公开(公告)号：US20190120734A1

公开(公告)日：2019-04-25

申请号：US16208557

申请日：2018-12-03

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Thomas M. BAER ,  Michael G. YOUNGQUIST ,  Brian W. DONOVAN ,  Alan E. WESSEL ,  Norbert H. LECLERC ,  Michael A. SMITH ,  Craig S. BARKER ,  George M. DAWSON

IPC: G01N1/28 ,  G01B11/00

Abstract: Systems and methods for automated laser microdissection are disclosed including automatic slide detection, position detection of cutting and capture lasers, focus optimization for cutting and capture lasers, energy and duration optimization for cutting and capture lasers, inspection and second phase capture and/or ablation in a quality control station and tracking information for linking substrate carrier or output microdissected regions with input sample or slide.

公开(公告)号：US20140335560A1

公开(公告)日：2014-11-13

申请号：US14275812

申请日：2014-05-12

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Thomas M. BAER ,  Michael G. YOUNGQUIST ,  Brian W. DONOVAN ,  Alan E. WESSEL ,  Norbert H. LECLERC ,  Michael A. SMITH ,  Craig S. BARKER ,  George M. DAWSON

IPC: G01N1/28 ,  G01B11/00

CPC classification number: G01N1/2813 ,  G01B11/002 ,  G01N2001/282 ,  G01N2001/284 ,  Y10T156/10 ,  Y10T156/1054

Abstract: Systems and methods for automated laser microdissection are disclosed including automatic slide detection, position detection of cutting and capture lasers, focus optimization for cutting and capture lasers, energy and duration optimization for cutting and capture lasers, inspection and second phase capture and/or ablation in a quality control station and tracking information for linking substrate carrier or output microdissected regions with input sample or slide.

Abstract translation: 公开了用于自动激光显微切割的系统和方法，包括自动滑动检测，切割和捕获激光器的位置检测，用于切割和捕获激光器的聚焦优化，用于切割和捕获激光器的能量和持续时间优化，检查和第二相捕获和/或消融 质量控制站和用于将衬底载体或输出显微切割区域与输入样品或载片连接的跟踪信息。

公开(公告)号：US20200284702A1

公开(公告)日：2020-09-10

申请号：US16790595

申请日：2020-02-13

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Thomas M. BAER ,  Michael G. Youngquist ,  Brian W. Donovan ,  Alan E. Wessel ,  Norbert H. Leclerc ,  Michael A. Smith ,  Craig S. Barker ,  George M. Dawson

IPC: G01N1/28 ,  G01B11/00

Abstract: Systems and methods for automated laser microdissection are disclosed including automatic slide detection, position detection of cutting and capture lasers, focus optimization for cutting and capture lasers, energy and duration optimization for cutting and capture lasers, inspection and second phase capture and/or ablation in a quality control station and tracking information for linking substrate carrier or output microdissected regions with input sample or slide.

公开(公告)号：US20160003717A1

公开(公告)日：2016-01-07

申请号：US14796760

申请日：2015-07-10

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Thomas M. BAER ,  Robert H. REAMEY ,  Keith E. MORAVICK ,  David F. HEAD ,  Bruce J. RICHARDSON ,  Derrick RICHARDSON

IPC: G01N1/30

CPC classification number: G01N1/30 ,  G01N1/2813 ,  G01N1/40 ,  G01N2001/284 ,  Y10T436/25375 ,  Y10T436/255

Abstract: The present invention generally discloses an extraction system that provides a locale for fluid processing and extraction on a post-microcapture transfer film. The extraction system includes a transfer film carrier and an extraction device forming a reservoir. The extraction system selectively excludes regions of the transfer film from the reservoir to advantageously reduce contamination due to matter adhered to the transfer film by non-specific transfer.

Abstract translation: 本发明通常公开了一种提取系统，其提供用于后微量捕获转移膜上的流体处理和萃取的区域。 提取系统包括转印膜载体和形成储存器的提取装置。 提取系统选择性地从储存器排除转印膜的区域，以有利地减少由于通过非特异性转移附着在转印膜上的物质引起的污染。