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公开(公告)号：US11702620B2
公开(公告)日：2023-07-18
申请号：US15566427
申请日：2016-04-26
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Evan D. Brutinel , Mary B. Forester , Adam J. Stanenas , Jason W. Bjork
CPC classification number: C12M1/045 , C12M1/005 , C12M1/007 , C12M1/14 , C12M23/14 , C12M23/22 , C12M25/02 , C12M25/06 , C12M41/34 , C12M41/36 , C12N1/20 , C12Q1/04
Abstract: A device for culturing anaerobic microorganisms is provided. The device comprises a body comprising a waterproof base, a waterproof coversheet attached to the base, and a growth compartment disposed between the base and the coversheet. The growth compartment has a perimeter and an opening that provides liquid access to the growth compartment. A portion of the perimeter is defined by a waterproof seal. The portion includes >50% of the perimeter. A dry cold water-soluble gelling agent is adhered to the base in the growth compartment. A dry first oxygen-scavenging reagent is disposed in the growth compartment.
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公开(公告)号：US20230294054A1
公开(公告)日：2023-09-21
申请号：US18297504
申请日：2023-04-07
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Trevor G. WILLIAMS
IPC: B01F35/41 , C12M1/02 , C12M1/00 , C12M1/10 , B01F27/07 , B01F27/2111 , B01F27/2121 , B01F35/513
CPC classification number: B01F35/4111 , C12M1/02 , C12M1/007 , C12M1/10 , B01F27/071 , B01F27/2111 , B01F27/2121 , B01F35/513 , B01F2101/44
Abstract: A method for operating a bioreactor includes passing a drive shaft into a first tubular connector and a second tubular connector projecting from the first tubular connector, the first tubular connector and the second tubular connector being at least partially disposed within a container, the first tubular connector being more flexible than the second tubular connector, the second tubular connector having a length that comprises at least 20% of a combined length of the first tubular connector and the second tubular connector. Rotating the drive shaft so as to rotate the first tubular connector and the second tubular connector within the container.
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3.发明授权公开(公告)号：US11713438B2
公开(公告)日：2023-08-01
申请号：US17120723
申请日：2020-12-14
Applicant: Perimeter Medical Imaging, Inc.
Inventor： Chao Fan , Elizabeth A. Munro , David Rempel , James Jackson
IPC: G01N1/28 , C12M1/00 , G01N35/00 , A61B10/00 , G02B21/34 , B01L3/00 , C12M1/26 , G01N33/483 , G06T7/00 , C12M3/00
CPC classification number: C12M1/007 , A61B10/0096 , B01L3/505 , C12M1/268 , C12M23/14 , C12M23/22 , G01N1/28 , G01N33/4833 , G01N35/00029 , G02B21/34 , G06T7/0012 , B01L2200/18 , B01L2300/044 , B01L2300/047 , B01L2300/048 , B01L2300/049 , B01L2300/123 , B01L2400/049 , C12M23/26 , C12M23/46 , G01N2035/00059
Abstract: Embodiments described herein relate to an apparatus for positioning and securing an excised biological tissue specimen for imaging and analysis. In some embodiments, an apparatus includes a sample bag defining an inner volume configured to receive a biological tissue sample, and a sealing member coupled to the sample bag. An imaging window is disposed and configured to be placed in contact with at least a portion of the biological tissue sample, and a positioning member is coupled to the imaging window and is configured to be disposed against the sealing member to substantially seal the inner volume. The positioning member includes a vacuum port disposed and configured to be aligned with a vacuum source to withdraw air from the inner volume of the sample bag.
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公开(公告)号：US20180223233A1
公开(公告)日：2018-08-09
申请号：US15749609
申请日：2016-07-01
Applicant: HITACHI, LTD. , FUJIMORI KOGYO CO., LTD.
Inventor： Masaru NANBA , Takashi ANDOU , Yui SUGITA , Sei MURAKAMI , Hiroyuki MATSUDA
CPC classification number: C12M1/06 , C12M1/007 , C12M1/02 , C12M3/00 , C12M23/14 , C12M23/26 , C12M23/48 , C12M27/20
Abstract: A single-use cell culturing apparatus and a culturing bag are provided, each of which can improve efficiency of stirring a culture solution and further reduce a possibility of leakage of the culture solution. The single-use cell culturing apparatus of the present invention includes a housing that accommodates the culturing bag which is flexible and can seal the culture solution inside thereof. The housing has, on an inner surface thereof, a curved convex-shaped protrusion provided at a portion of a contact face at which the housing is in contact with the culturing bag. The culturing bag of the present invention is accommodated in the housing of the single-use cell culturing apparatus; is flexible; and can seal the culture solution inside thereof. The culturing bag includes a concave portion having a shape corresponding to the curved convex protrusion disposed on a part of the housing.
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Patent Agency Ranking
公开(公告)号：US20180127696A1
公开(公告)日：2018-05-10
申请号：US15574516
申请日：2016-05-24
Applicant: NIPRO CORPORATION
Inventor： Masakatsu TAKEUCHI , Atsushi TAGUCHI
CPC classification number: C12M3/043 , B01L3/50 , B01L3/563 , B01L2200/025 , B01L2200/026 , B01L2300/046 , C12M1/007 , C12M1/065 , C12M1/10 , C12M1/38 , C12M3/02 , C12M23/14 , C12M23/34 , C12M23/42 , C12M23/44 , C12M23/50 , C12M29/00 , C12M41/48
Abstract: A compact culture device capable of performing large-scale culture in an aseptic state. A culture device has a culture bag which has ports through which a liquid flows and enables cell culture, a bag holding portion having holding plates holding the culture bag and rotating shafts, a rotation mechanism supporting and rotating the rotating shaft, a liquid supply/discharge mechanism supplying and discharging a liquid to/from the culture bag, and a rotation control portion controlling the rotation of the rotation mechanism. The rotation control portion brings the bag holding portion into a first position in parallel with the approximately horizontal direction according to a first information, brings the bag holding portion into a second position when a culture medium in the culture bag is caused to flow out of the port according to a second information, and brings the bag holding portion into a third position in parallel with the approximately vertical direction at least when a cell suspension in the culture bag is caused to flow out of the port according to a third information.
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公开(公告)号：US12077742B2
公开(公告)日：2024-09-03
申请号：US16853865
申请日：2020-04-21
Applicant: Life Technologies Corporation
Inventor： Nephi D. Jones , Christopher D. Brau
IPC: C12M1/06 , B01F27/1111 , B01F27/191 , B01F27/2111 , B01F35/41 , B01F35/513 , B01F101/44 , C12M1/00 , C12M1/02 , C12N1/00
CPC classification number: C12M27/02 , B01F27/1111 , B01F27/191 , B01F27/2111 , B01F35/4121 , B01F35/513 , C12M1/007 , C12M1/02 , C12M23/14 , C12N1/00 , B01F2101/44
Abstract: A method for mixing a biological suspension includes disposing a biological suspension within a compartment of a container, the biological suspension comprising cells or microorganisms suspended within a nutrient growth medium; and rotating a first drive line and laterally spaced apart second drive line within the compartment of the container so as to cause the drive lines to twist into a helical configuration and mix the biological suspension.
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公开(公告)号：US11654408B2
公开(公告)日：2023-05-23
申请号：US16421168
申请日：2019-05-23
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Trevor G. Williams
IPC: B01F27/2111 , B01F35/513 , B01F35/41 , C12M1/02 , C12M1/00 , C12M1/10 , B01F27/07 , B01F27/2121 , B01F101/44
CPC classification number: B01F35/4111 , B01F27/071 , B01F27/2111 , B01F27/2121 , B01F35/513 , C12M1/007 , C12M1/02 , C12M1/10 , B01F2101/44
Abstract: A method for operating a bioreactor includes passing a drive shaft into a first tubular connector and a second tubular connector projecting from the first tubular connector, the first tubular connector and the second tubular connector being at least partially disposed within a container, the first tubular connector being more flexible than the second tubular connector, the second tubular connector having a length that comprises at least 20% of a combined length of the first tubular connector and the second tubular connector. Rotating the drive shaft so as to rotate the first tubular connector and the second tubular connector within the container.
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公开(公告)号：US20180258377A1
公开(公告)日：2018-09-13
申请号：US15761114
申请日：2015-09-28
Applicant: Hitachi High-Technologies Corporation
Inventor： Akihiro SHIMASE , Toshinari SAKURAI
CPC classification number: C12M1/007 , B01F3/08 , B01F5/102 , B01F15/0245 , B81B3/0097 , C12M23/40 , F04B45/06 , F16K7/06 , F16K11/022
Abstract: Provided are a flow passage module which can achieve complete liquid substitution in a circulating flow passage with a simple structure, and a cell culture apparatus using said flow passage module. A flow passage module comprises: a flexible branching section which is provided with a first branching flow passage connected with an inflow passage for a fluid, a second branching flow passage connected with an outflow passage, a third branching flow passage connected with an entry-side end part of a circulating flow passage, and a fourth branching flow passage connected with an exit-side end part of the circulating flow passage, and which enables the branching flow passages to be communicated with each other; and a communication state switching part which has opening/closing members for closing and opening the desired branching flow passage from among the plurality of branching flow passages.
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公开(公告)号：US20180100131A1
公开(公告)日：2018-04-12
申请号：US15566427
申请日：2016-04-26
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Evan D. Brutinel , Mary B. Forester , Adam J. Stanenas , Jason W. Bjork
CPC classification number: C12M1/045 , C12M1/005 , C12M1/007 , C12M1/14 , C12M23/14 , C12M23/22 , C12M25/02 , C12M25/06 , C12M41/34 , C12M41/36 , C12N1/20 , C12Q1/04
Abstract: A device for culturing anaerobic microorganisms is provided. The device comprises a body comprising a waterproof base, a waterproof coversheet attached to the base, and a growth compartment disposed between the base and the coversheet. The growth compartment has a perimeter and an opening that provides liquid access to the growth compartment. A portion of the perimeter is defined by a waterproof seal. The portion includes >50% of the perimeter. A dry cold water-soluble gelling agent is adhered to the base in the growth compartment. A dry first oxygen-scavenging reagent is disposed in the growth compartment.
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