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公开(公告)号：US20180325244A1
公开(公告)日：2018-11-15
申请号：US15773761
申请日：2016-10-27
发明人： Ji Seon Jeong , Ju Hee Shin , Sung Hwan Bang , Ju Young Jung , Kil Seuk Byun , Kyong Min Lee
CPC分类号： A45D44/002 , A45D37/00 , A45D44/22 , A45D2200/1027 , A45D2200/1036 , A61K8/0212 , A61K8/731 , A61K9/0014 , A61K9/7007 , A61K9/7046 , A61L15/28 , A61L15/60 , A61L26/0023 , A61L26/008 , A61Q19/00 , C08J3/075 , C08J5/18 , C08J2301/28 , C08L1/26
摘要： The present invention relates to a method of preparing a dry hydrogel sheet including the steps of: preparing a cellulose ether dispersion solution; transferring the dispersion solution to a coater while maintaining the temperature of the dispersion solution in the range of a gelation temperature of the dispersion solution to a boiling point of a dispersion medium; applying the dispersion solution transferred to the coater as a sheet; preparing a hydrogel sheet by cooling the applied dispersion solution to induce gelation; and drying the hydrogel sheet. Since the dry hydrogel sheet prepared by the method has a low moisture content, it is possible to ensure the stability of active ingredients, quantify functional components to be applied to the dry hydrogel sheet, and ensure the uniformity of the surface appearance and thickness of the dry hydrogel sheet, which results in the improvement of the quality of a final product.
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2.发明申请公开(公告)号：US20180214354A1
公开(公告)日：2018-08-02
申请号：US15762989
申请日：2016-09-23
发明人： Ju Hee Shin , Ji Seon Jeong , Sung Hwan Bang , Ju Young Jung
CPC分类号： A61K8/0212 , A61K8/042 , A61K8/20 , A61K8/73 , A61K8/731 , A61L15/225 , A61L15/28 , A61L15/425 , A61Q19/00 , C08L5/12 , C08L1/26
摘要： The present invention relates to a composition for a hydrogel sheet including a cellulose ether, a gelling agent, and a gelling promoter, a hydrogel sheet prepared therefrom, and a method of preparing the hydrogel sheet. According to the present invention, the composition for a hydrogel sheet can be used to prepare a hydrogel sheet capable of maintaining the shape thereof without a support by limiting a type of the gelling agent and/or a viscosity of the cellulose ether included in the composition.
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公开(公告)号：US10562983B2
公开(公告)日：2020-02-18
申请号：US15104561
申请日：2014-12-15
发明人： Sung Hwan Bang , Ju Hee Shin , Jin Ryul Son , Kyung Yeol Park , Jeong Hee Chun , Ji Seon Jeong , Sang Youb Lee
摘要： Disclosed are a method for preparing hydroxypropyl methylcellulose acetate succinate (HPMCAS) grains and HPMCAS grains. The disclosed method for preparing HPMCAS grains comprises: a step of esterifying hydroxypropyl methylcellulose (HPMC), acetic anhydride, and succinic anhydride in a reaction medium in the presence of a catalyst so as to obtain a reaction solution containing HPMCAS (esterification step); and a step of continuously or intermittently putting the reaction solution into water so as to form grains (granulating step).
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公开(公告)号：US10765194B2
公开(公告)日：2020-09-08
申请号：US15773761
申请日：2016-10-27
发明人： Ji Seon Jeong , Ju Hee Shin , Sung Hwan Bang , Ju Young Jung , Kil Seuk Byun , Kyong Min Lee
IPC分类号： A45D44/00 , A45D44/22 , A61K8/02 , A61K9/70 , C08J3/075 , C08J5/18 , A45D37/00 , A61Q19/00 , A61K9/00 , A61L15/60 , A61L15/28 , A61K8/73 , A61L26/00
摘要： The present invention relates to a method of preparing a dry hydrogel sheet including the steps of: preparing a cellulose ether dispersion solution; transferring the dispersion solution to a coater while maintaining the temperature of the dispersion solution in the range of a gelation temperature of the dispersion solution to a boiling point of a dispersion medium; applying the dispersion solution transferred to the coater as a sheet; preparing a hydrogel sheet by cooling the applied dispersion solution to induce gelation; and drying the hydrogel sheet. Since the dry hydrogel sheet prepared by the method has a low moisture content, it is possible to ensure the stability of active ingredients, quantify functional components to be applied to the dry hydrogel sheet, and ensure the uniformity of the surface appearance and thickness of the dry hydrogel sheet, which results in the improvement of the quality of a final product.
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5.发明申请公开(公告)号：US20200253841A1
公开(公告)日：2020-08-13
申请号：US16807583
申请日：2020-03-03
发明人： Ju Hee Shin , Ji Seon Jeong , Sung Hwan Bang , Ju Young Jung
摘要： A composition for a hydrogel sheet may include a cellulose ether, a gelling agent, and a gelling promoter, where an aqueous 2 wt % solution of the cellulose either may have a viscosity of 3 cps to 300 cps, as measured under a condition of 20 ° C. using an Ubbelohde viscometer. The gelling agent may include one or more selected from the group consisting of carrageenan, locust bean gum, mannose, and water chestnut flour.
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