公开(公告)号：US11261481B2

公开(公告)日：2022-03-01

申请号：US16804060

申请日：2020-02-28

Applicant: LUMINEX CORPORATION

Inventor： Doug Whitman ,  Nicolas Arab ,  Chuck Collins

IPC: C12Q1/68 ,  C07H21/00 ,  C12Q1/6818

Abstract: Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of primers or probes that comprise a non-natural nucleotide linked to a reporter. Target nucleic acids are detected by the polymerization of a complementary probe or primer that incorporated a cognate non-natural nucleotide linked to a quencher.

公开(公告)号：US20150044680A1

公开(公告)日：2015-02-12

申请号：US14456239

申请日：2014-08-11

Applicant: LUMINEX CORPORATION

Inventor： Doug WHITMAN ,  Nicolas Arab ,  Chuck Collins

IPC: C12Q1/68

CPC classification number: C12Q1/6818 ,  C12Q2525/186 ,  C12Q2527/107 ,  C12Q2561/109 ,  C12Q2525/161 ,  C12Q2525/301 ,  C12Q2533/101 ,  C12Q2537/143

Abstract: Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of primers or probes that comprise a non-natural nucleotide linked to a reporter. Target nucleic acids are detected by the polymerization of a complementary probe or primer that incorporated a cognate non-natural nucleotide linked to a quencher.

Abstract translation: 提供了用于检测和定量核酸的方法和组合物。 在某些实施方案中，方法涉及使用包含与报告基团连接的非天然核苷酸的引物或探针。 通过掺入与猝灭剂连接的同源非天然核苷酸的互补探针或引物的聚合来检测靶核酸。

公开(公告)号：US20140220702A1

公开(公告)日：2014-08-07

申请号：US14169284

申请日：2014-01-31

Applicant: LUMINEX CORPORATION

Inventor： Ross JOHNSON ,  Chuck Collins

IPC: G01N1/38

CPC classification number: B01L3/502715 ,  B01L3/502792 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/0672 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/0427 ,  B01L2400/0478 ,  B01L2400/0481 ,  B01L2400/0683 ,  Y10T436/2575

Abstract: Fluid storage containers and analysis cartridges for use in assay processes are presented. In addition, systems comprising such storage containers and analysis cartridges and methods of using such containers and cartridges are presented as well. In specific embodiments, fluid storage containers are configured to be coupled to analysis cartridges in a first stage and a second stage.

Abstract translation: 介绍了用于测定过程的流体储存容器和分析盒。 此外，还提供了包括这种存储容器和分析盒的系统以及使用这种容器和盒的方法。 在具体实施例中，流体存储容器被配置为在第一阶段和第二阶段中耦合到分析盒。

公开(公告)号：US10688489B2

公开(公告)日：2020-06-23

申请号：US15427432

申请日：2017-02-08

Applicant: LUMINEX CORPORATION

Inventor： Ross Johnson ,  Chuck Collins

IPC: B01L3/00

Abstract: Fluid storage containers and analysis cartridges for use in assay processes are presented. In addition, systems comprising such storage containers and analysis cartridges and methods of using such containers and cartridges are presented as well. In specific embodiments, fluid storage containers are configured to be coupled to analysis cartridges in a first stage and a second stage.

公开(公告)号：US09657332B2

公开(公告)日：2017-05-23

申请号：US14456239

申请日：2014-08-11

Applicant: LUMINEX CORPORATION

Inventor： Doug Whitman ,  Nicolas Arab ,  Chuck Collins

IPC: C12Q1/68 ,  C07H21/00

CPC classification number: C12Q1/6818 ,  C12Q2525/186 ,  C12Q2527/107 ,  C12Q2561/109 ,  C12Q2525/161 ,  C12Q2525/301 ,  C12Q2533/101 ,  C12Q2537/143

Abstract: Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of primers or probes that comprise a non-natural nucleotide linked to a reporter. Target nucleic acids are detected by the polymerization of a complementary probe or primer that incorporated a cognate non-natural nucleotide linked to a quencher.

公开(公告)号：US11517898B2

公开(公告)日：2022-12-06

申请号：US15931695

申请日：2020-05-14

Applicant: LUMINEX CORPORATION

Inventor： Ross Johnson ,  Chuck Collins

IPC: B01L3/00

Abstract: Fluid storage containers and analysis cartridges for use in assay processes are presented. In addition, systems comprising such storage containers and analysis cartridges and methods of using such containers and cartridges are presented as well. In specific embodiments, fluid storage containers are configured to be coupled to analysis cartridges in a first stage and a second stage.

公开(公告)号：US09597685B2

公开(公告)日：2017-03-21

申请号：US14169284

申请日：2014-01-31

Applicant: LUMINEX CORPORATION

Inventor： Ross Johnson ,  Chuck Collins

IPC: B01L3/00

CPC classification number: B01L3/502715 ,  B01L3/502792 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/0672 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/0427 ,  B01L2400/0478 ,  B01L2400/0481 ,  B01L2400/0683 ,  Y10T436/2575

Abstract: Fluid storage containers and analysis cartridges for use in assay processes are presented. In addition, systems comprising such storage containers and analysis cartridges and methods of using such containers and cartridges are presented as well. In specific embodiments, fluid storage containers are configured to be coupled to analysis cartridges in a first stage and a second stage.