Substituted thieno [2,3-d] pyrimidines as HIV inhibitors
    10.
    发明授权
    Substituted thieno [2,3-d] pyrimidines as HIV inhibitors 失效
    取代噻吩并[2,3-d]嘧啶作为HIV抑制剂

    公开(公告)号:US08324223B2

    公开(公告)日:2012-12-04

    申请号:US13470119

    申请日:2012-05-11

    CPC分类号: C07D495/04

    摘要: This application concerns certain 4-cyanophenylamino-substituted bicyclic heterocycles of formula I where the dashed line represents a double bond that may be located either between A and C(V) or between C(V) and D, where A is S or C(Z); D is S or C(W); provided that one and only one of A and D is S; where T is NH, O, or S; and where other substituents are defined herein. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.

    摘要翻译: 本申请涉及式I的某些4-氰基苯基氨基取代的双环杂环,其中虚线表示可以位于A和C(V)之间或C(V)和D之间的双键,其中A是S或C( Z); D为S或C(W); A和D中只有一个是S; 其中T是NH,O或S; 并且其中其它取代基在本文中定义。 这些化合物是非核苷逆转录酶抑制剂,具有抗HIV治疗的潜力。