公开(公告)号：US20170014824A1

公开(公告)日：2017-01-19

申请号：US15211565

申请日：2016-07-15

申请人： Lawrence M. Boyd ,  John J. Ratcliffe, JR. ,  Andres Jose Garcia ,  Todd Christopher McDevitt

发明人： Lawrence M. Boyd ,  John J. Ratcliffe, JR. ,  Andres Jose Garcia ,  Todd Christopher McDevitt

IPC分类号： B01L3/00

CPC分类号： B01L3/502761 ,  B01L3/502715 ,  B01L9/527 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/0652 ,  B01L2200/0689 ,  B01L2300/043 ,  B01L2300/0822 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/0877 ,  B01L2300/123 ,  B01L2400/0478 ,  C12M47/04

摘要： A device for use in sorting cells comprises a first body member having a pair of longitudinally spaced through passages opening to a inner surface. A second body member has an inner surface and a portion defining an opening. The first body member is configured to be mounted to the second body member such that a gasket is disposed between the inner surface of the first body member. The substrate is disposed between the gasket and the inner surface of the second body member for overlying the opening in the second body member. The openings in the first body member open onto an inner surface of the substrate at opposite ends of a channel defined by the inner surface of the first body member, an elongated longitudinal opening in the gasket and the substrate.

摘要翻译： 用于分选细胞的装置包括第一主体构件，其具有通向内表面的一对纵向间隔开的通道。 第二主体构件具有内表面和限定开口的部分。 第一主体构件被构造成安装到第二主体构件，使得垫圈设置在第一主体构件的内表面之间。 基板设置在垫圈和第二主体构件的内表面之间，用于覆盖第二主体构件中的开口。 第一主体构件中的开口在由第一主体构件的内表面限定的通道的相对端处，衬垫的内表面上开口，衬垫中的细长纵向开口和衬底。

公开(公告)号：US10106780B2

公开(公告)日：2018-10-23

申请号：US14128547

申请日：2012-06-21

申请人： Ankur Singh ,  Shalu Suri ,  Todd Christopher McDevitt ,  Hang Lu ,  Andres Jose Garcia

发明人： Ankur Singh ,  Shalu Suri ,  Todd Christopher McDevitt ,  Hang Lu ,  Andres Jose Garcia

IPC分类号： C12N5/074 ,  C12N5/0797 ,  C12Q1/686 ,  G01N33/569

摘要： The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces.

公开(公告)号：US20140357506A1

公开(公告)日：2014-12-04

申请号：US14128547

申请日：2012-06-21

申请人： Ankur Singh ,  Shalu Suri ,  Todd Christopher McDevitt ,  Hang Lu ,  Andres Jose Garcia

发明人： Ankur Singh ,  Shalu Suri ,  Todd Christopher McDevitt ,  Hang Lu ,  Andres Jose Garcia

IPC分类号： C12N5/074 ,  C12Q1/68 ,  C12N5/0797 ,  G01N33/569

CPC分类号： C12N5/0696 ,  C12N5/0623 ,  C12N2506/45 ,  C12N2509/10 ,  C12N2527/00 ,  C12N2539/10 ,  C12Q1/686 ,  G01N33/56966

摘要： The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces.

摘要翻译： 本发明提供了从细胞混合物（例如培养物中粘附细胞的混合物）分离源自其的干细胞或细胞的方法。 通过应用选择性分离力来实现细胞分离。