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公开(公告)号：US20080254092A1
公开(公告)日：2008-10-16
申请号：US12092863
申请日：2006-11-08
CPC分类号： A61K35/34 , A61K35/545
摘要： Compositions containing acellularized biomaterial derived from differentiating pluripotent cells, for example, embryonic stem cells are provided. The acellularized biomaterial can be used to promote wound healing, promote tissue regeneration, or inhibit scarring. Methods for using the acellularized biomaterial for treating degenerative diseases are also provided.
摘要翻译： 提供了含有来自分化多能细胞的非细胞生物材料的组合物，例如胚胎干细胞。 无细胞生物材料可用于促进伤口愈合，促进组织再生或抑制瘢痕形成。 还提供了使用无细胞生物材料治疗退行性疾病的方法。
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2.发明授权公开(公告)号：US10106780B2
公开(公告)日：2018-10-23
申请号：US14128547
申请日：2012-06-21
IPC分类号： C12N5/074 , C12N5/0797 , C12Q1/686 , G01N33/569
摘要： The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces.
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公开(公告)号：US20170014824A1
公开(公告)日：2017-01-19
申请号：US15211565
申请日：2016-07-15
IPC分类号： B01L3/00
CPC分类号： B01L3/502761 , B01L3/502715 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0652 , B01L2200/0689 , B01L2300/043 , B01L2300/0822 , B01L2300/0864 , B01L2300/0867 , B01L2300/0877 , B01L2300/123 , B01L2400/0478 , C12M47/04
摘要： A device for use in sorting cells comprises a first body member having a pair of longitudinally spaced through passages opening to a inner surface. A second body member has an inner surface and a portion defining an opening. The first body member is configured to be mounted to the second body member such that a gasket is disposed between the inner surface of the first body member. The substrate is disposed between the gasket and the inner surface of the second body member for overlying the opening in the second body member. The openings in the first body member open onto an inner surface of the substrate at opposite ends of a channel defined by the inner surface of the first body member, an elongated longitudinal opening in the gasket and the substrate.
摘要翻译： 用于分选细胞的装置包括第一主体构件，其具有通向内表面的一对纵向间隔开的通道。 第二主体构件具有内表面和限定开口的部分。 第一主体构件被构造成安装到第二主体构件，使得垫圈设置在第一主体构件的内表面之间。 基板设置在垫圈和第二主体构件的内表面之间，用于覆盖第二主体构件中的开口。 第一主体构件中的开口在由第一主体构件的内表面限定的通道的相对端处，衬垫的内表面上开口，衬垫中的细长纵向开口和衬底。
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公开(公告)号：US09211307B2
公开(公告)日：2015-12-15
申请号：US12092863
申请日：2006-11-08
IPC分类号： A61K35/34 , A61K35/54 , A61K35/545
CPC分类号： A61K35/34 , A61K35/545
摘要： Compositions containing acellularized biomaterial derived from differentiating pluripotent cells, for example, embryonic stem cells are provided. The acellularized biomaterial can be used to promote wound healing, promote tissue regeneration, or inhibit scarring. Methods for using the acellularized biomaterial for treating degenerative diseases are also provided.
摘要翻译： 提供了含有来自分化多能细胞的非细胞生物材料的组合物，例如胚胎干细胞。 无细胞生物材料可用于促进伤口愈合，促进组织再生或抑制瘢痕形成。 还提供了使用无细胞生物材料治疗退行性疾病的方法。
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5.发明申请ADHESIVE SIGNATURE-BASED METHODS FOR THE ISOLATION OF STEM CELLS AND CELLS DERIVED THEREFROM 审中-公开用于分离干细胞和分泌的细胞的基于签名的基于签名的方法公开(公告)号：US20140357506A1
公开(公告)日：2014-12-04
申请号：US14128547
申请日：2012-06-21
IPC分类号： C12N5/074 , C12Q1/68 , C12N5/0797 , G01N33/569
CPC分类号： C12N5/0696 , C12N5/0623 , C12N2506/45 , C12N2509/10 , C12N2527/00 , C12N2539/10 , C12Q1/686 , G01N33/56966
摘要： The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces.
摘要翻译： 本发明提供了从细胞混合物（例如培养物中粘附细胞的混合物）分离源自其的干细胞或细胞的方法。 通过应用选择性分离力来实现细胞分离。
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