公开(公告)号：US20110194117A1

公开(公告)日：2011-08-11

申请号：US13123683

申请日：2010-01-11

申请人： Huikai Xie ,  Andrea Pais ,  Lei Wu ,  Sean Robert Samuelson ,  Shuguang Guo

发明人： Huikai Xie ,  Andrea Pais ,  Lei Wu ,  Sean Robert Samuelson ,  Shuguang Guo

IPC分类号： G01J3/45 ,  G01J3/08

CPC分类号： G01J3/4532 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0256 ,  G01J3/0291 ,  G01J3/45

摘要： Methods and designs for providing reduced sensitivity to mirror tilt in Fourier transform spectrometers are disclosed. According to an embodiment for two-directional tilt compensation, the FT spectrometer can include a beam splitter positioned to receive an incoming beam from a light source and split the incoming beam into a first sub-beam and a second sub-beam, a corner-cube retroreflector positioned to receive the first sub-beam from the beam splitter, a dual reflective mirror positioned to receive the first sub-beam from the corner-cube retroreflector at one surface and the second sub-beam at the other surface. An optical path delay can be created using a set of mirrors, tilting the beam splitter and/or a glass cube.

摘要翻译： 公开了在傅里叶变换光谱仪中提供对镜面倾斜的灵敏度降低的方法和设计。 根据用于双向倾斜补偿的实施例，FT光谱仪可以包括分束器，其被定位成接收来自光源的入射光束，并将入射光束分成第一子光束和第二子光束， 立方体后向反射器被定位成从分束器接收第一子光束;双反射镜，定位成在一个表面处接收来自角立方后视反射器的第一子光束，而在另一个表面处接收第二子光束。 可以使用一组反射镜，倾斜分束器和/或玻璃立方体来产生光路延迟。

公开(公告)号：US20110139990A1

公开(公告)日：2011-06-16

申请号：US12989871

申请日：2009-08-04

申请人： Huikai Xie ,  Lei Wu ,  Andrea Pais ,  Sean Robert Samuelson

发明人： Huikai Xie ,  Lei Wu ,  Andrea Pais ,  Sean Robert Samuelson

IPC分类号： G01N21/35 ,  G01J3/45

CPC分类号： G01J3/4535 ,  G01J5/08 ,  G01J5/0853 ,  G01J5/38 ,  G01N2021/3595 ,  G02B26/0866

摘要： A MEMS-based Fourier Transform (FT) spectrometer is provided. According to an embodiment, the MEMS-based FT spectrometer is an FT infrared (FTIR) spectrometer. The FT spectrometer can include a beam splitter positioned to receive an incoming beam from a light source and split the incoming beam into a first sub-beam and a second sub-beam, a fixed mirror positioned to receive the first sub-beam from the beam splitter, a scanning MEMS mirror positioned to receive the second sub-beam from the beam splitter, and a photodetector, wherein a reflected first sub-beam from the fixed mirror and a reflected second sub-beam from the scanning MEMS mirror recombine at the beam splitter and become directed to the photodetector. According to one embodiment, the photodetector is a MEMS-based IR detector. In addition, the MEMS-based IR detector can be an un-cooled IR detector having a capacitive sensing structure.

摘要翻译： 提供了基于MEMS的傅里叶变换（FT）光谱仪。 根据实施例，基于MEMS的FT光谱仪是FT红外（FTIR）光谱仪。 FT分光计可以包括分束器，其被定位成接收来自光源的入射光束，并将入射光束分成第一子光束和第二子光束，固定镜定位成从光束接收第一子光束 分离器，定位成从分束器接收第二子光束的扫描MEMS镜和光电检测器，其中来自固定镜的反射的第一子光束和来自扫描MEMS镜的反射的第二子光束在光束处复合 分离器并且被引导到光电检测器。 根据一个实施例，光电检测器是基于MEMS的IR检测器。 此外，基于MEMS的IR检测器可以是具有电容感测结构的未冷却的IR检测器。

公开(公告)号：US20100033788A1

公开(公告)日：2010-02-11

申请号：US12534514

申请日：2009-08-03

申请人： Huikai Xie ,  Sarah Maley ,  Paul McManamon ,  Thomas Nelson ,  Lei Wu ,  Andrea Pais ,  Kemiao Jia

发明人： Huikai Xie ,  Sarah Maley ,  Paul McManamon ,  Thomas Nelson ,  Lei Wu ,  Andrea Pais ,  Kemiao Jia

IPC分类号： G02B26/10 ,  G02B26/08 ,  H01L21/50

CPC分类号： G06Q10/06 ,  G06Q10/06313 ,  G06Q30/0601 ,  G06Q40/12

摘要： A high-fill-factor and large-aperture tip-tilt micromirror array is disclosed. Electrothermal actuation can be used to obtain a large scan range, and the actuation engine can be hidden underneath the mirror plate for high fill factor. In one embodiment, inverted-series-connected (ISC) bimorph actuators can be used to achieve tilt and piston scanning. Embodiments can be used to implement optical phased array technology for steering active and passive electro-optical systems based on MEMS mirrors.

摘要翻译： 公开了高填充因子和大孔径尖端倾斜微镜阵列。 可以使用电热驱动来获得大的扫描范围，并且致动引擎可以隐藏在镜板的下面用于高填充因子。 在一个实施例中，可以使用反向串联连接（ISC）双压电晶片致动器来实现倾斜和活塞扫描。 可以使用实施例来实现用于转向基于MEMS镜的主动和无源电光系统的光相控阵技术。

公开(公告)号：US08776514B2

公开(公告)日：2014-07-15

申请号：US12743499

申请日：2008-12-15

申请人： Lei Wu ,  Huikai Xie

发明人： Lei Wu ,  Huikai Xie

IPC分类号： F01B29/10 ,  G02B26/00

CPC分类号： B81B3/0024 ,  B81B2201/032 ,  B81B2201/047 ,  B81B2203/053

摘要： A microactuator for displacing a platform vertically with respect to a substrate includes a first rigid frame, a first flexible bimorph beam connecting the first frame to the substrate, a second rigid frame, a second flexible bimorph beam connecting the second frame to the first frame, and a third flexible bimorph beam connecting a platform to the second frame. Activation of the first, second, and third flexible bimorph beams allows vertical displacement of the platform with respect to the substrate, with negligible lateral shift. A microactuator assembly includes a substrate, a plurality of first rigid frames, a plurality of first flexible bimorph beams, a plurality of second rigid frames, a plurality of second flexible bimorph beams, a platform, and a plurality of third flexible bimorph beams. Activation of the first, second, and third bimorph beams allows vertical displacement of the platform with respect to the substrate, with negligible lateral shift. A further embodiment with four identical such microactuators oriented at four sides of the platform, can achieve 1D or 2D angular scanning of the mirror plate by the activation of 1 or 2 adjacent microactuators.

摘要翻译： 用于使平台相对于衬底垂直移位的微致动器包括第一刚性框架，将第一框架连接到衬底的第一柔性双压电晶片梁，第二刚性框架，将第二框架连接到第一框架的第二柔性双压电晶片梁， 以及将平台连接到第二框架的第三柔性双压电晶片。 第一，第二和第三柔性双晶片束的激活允许平台相对于衬底的垂直位移，具有可忽略的横向偏移。 微致动器组件包括基板，多个第一刚性框架，多个第一柔性双压电晶片梁，多个第二刚性框架，多个第二柔性双压电晶片梁，平台和多个第三柔性双压电晶片。 第一，第二和第三双晶片束的激活允许平台相对于衬底的垂直位移，具有可忽略的横向偏移。 具有四个相同的这样的微致动器的另一实施例在平台的四个侧面定向，可以通过激活1或2个相邻微致动器来实现镜板的1D或2D角扫描。

公开(公告)号：US20100307150A1

公开(公告)日：2010-12-09

申请号：US12743499

申请日：2008-12-15

申请人： Lei Wu ,  Huikai Xie

发明人： Lei Wu ,  Huikai Xie

IPC分类号： F03G7/06

CPC分类号： B81B3/0024 ,  B81B2201/032 ,  B81B2201/047 ,  B81B2203/053

摘要： A microactuator for displacing a platform vertically with respect to a substrate includes a first rigid frame, a first flexible bimorph beam connecting the first frame to the substrate, a second rigid frame, a second flexible bimorph beam connecting the second frame to the first frame, and a third flexible bimorph beam connecting a platform to the second frame. Activation of the first, second, and third flexible bimorph beams allows vertical displacement of the platform with respect to the substrate, with negligible lateral shift. A microactuator assembly includes a substrate, a plurality of first rigid frames, a plurality of first flexible bimorph beams, a plurality of second rigid frames, a plurality of second flexible bimorph beams, a platform, and a plurality of third flexible bimorph beams. Activation of the first, second, and third bimorph beams allows vertical displacement of the platform with respect to the substrate, with negligible lateral shift. A further embodiment with four identical such microactuators oriented at four sides of the platform, can achieve 1D or 2D angular scanning of the mirror plate by the activation of 1 or 2 adjacent microactuators.

摘要翻译： 用于使平台相对于衬底垂直移位的微致动器包括第一刚性框架，将第一框架连接到衬底的第一柔性双压电晶片梁，第二刚性框架，将第二框架连接到第一框架的第二柔性双压电晶片梁， 以及将平台连接到第二框架的第三柔性双压电晶片。 第一，第二和第三柔性双晶片束的激活允许平台相对于衬底的垂直位移，具有可忽略的横向偏移。 微致动器组件包括基板，多个第一刚性框架，多个第一柔性双压电晶片梁，多个第二刚性框架，多个第二柔性双压电晶片梁，平台和多个第三柔性双压电晶片。 第一，第二和第三双晶片束的激活允许平台相对于衬底的垂直位移，具有可忽略的横向偏移。 具有四个相同的这样的微致动器的另一实施例在平台的四个侧面定向，可以通过激活1或2个相邻微致动器来实现镜板的1D或2D角扫描。

公开(公告)号：US08569009B2

公开(公告)日：2013-10-29

申请号：US11841972

申请日：2007-08-20

申请人： Ping Lin ,  Andrea Ghetti ,  Wenge Shi ,  Mengjia Tang ,  Gioulnar I. Harvie ,  Huimin Tao ,  Guoliang Tao ,  Lei Wu ,  David Cerny ,  Jia Xu

发明人： Ping Lin ,  Andrea Ghetti ,  Wenge Shi ,  Mengjia Tang ,  Gioulnar I. Harvie ,  Huimin Tao ,  Guoliang Tao ,  Lei Wu ,  David Cerny ,  Jia Xu

IPC分类号： C12Q1/24

摘要： Provided are methods and compositions for isolating and detecting rare cells from a biological sample containing other types of cells, particularly including debulking that uses a microfabricated filter for filtering samples. The enriched rare cells can be used in a downstream process such as identification, characterization or growth in culture, or in other ways. Also included is a method of determining tumor aggressiveness or the number or proportion of cancer cells in the enriched sample by detecting telomerase activity, nucleic acid or expression after enrichment of rare cells. Also provided is an efficient, rapid method to specifically remove red and white blood cells from a biological sample containing at least one of the cell types, leading to enrichment of rare target cells including circulating tumor (CTC), stromal, mesenchymal, endothelial, fetal, stem, or non-hematopoietic cells et cetera from a blood sample.

公开(公告)号：US08126274B2

公开(公告)日：2012-02-28

申请号：US11847959

申请日：2007-08-30

申请人： Mingjing Li ,  Wei-Ying Ma ,  Zhiwei Li ,  Lei Wu

发明人： Mingjing Li ,  Wei-Ying Ma ,  Zhiwei Li ,  Lei Wu

IPC分类号： G06K9/62

CPC分类号： G06K9/4685 ,  G06K9/4642 ,  G06K9/6278

摘要： Systems and methods for visual language modeling for image classification are described. In one aspect the systems and methods model training images corresponding to multiple image categories as matrices of visual words. Visual language models are generated from the matrices. In view of a given image, for example, provided by a user or from the Web, the systems and methods determine an image category corresponding to the given image. This image categorization is accomplished by maximizing the posterior probability of visual words associated with the given image over the visual language models. The image category, or a result corresponding to the image category, is presented to the user.

摘要翻译： 描述了用于图像分类的视觉语言建模的系统和方法。 在一个方面，系统和方法将对应于多个图像类别的训练图像建模为视觉词的矩阵。 视觉语言模型是从矩阵生成的。 考虑到例如由用户或从Web提供的给定图像，系统和方法确定对应于给定图像的图像类别。 这种图像分类是通过在视觉语言模型上最大化与给定图像相关联的视觉词的后验概率来实现的。 图像类别或与图像类别对应的结果被呈现给用户。

公开(公告)号：US07835425B1

公开(公告)日：2010-11-16

申请号：US12330218

申请日：2008-12-08

申请人： Pantas Sutardja ,  Lei Wu ,  Hongying Sheng

发明人： Pantas Sutardja ,  Lei Wu ,  Hongying Sheng

IPC分类号： H03K11/00 ,  H04L25/60 ,  H04L25/64

CPC分类号： G06F13/405

摘要： Circuits, architectures, systems and methods for facilitating data communications and/or reducing latency in data communications. The architecture includes a clock recovery loop receiving data from a host device and providing a recovered clock signal, a filter circuit receiving recovered clock signal information and providing a control signal that adjusts the transmitter clock in response to recovered clock signal information and the two clock signals, and a transmitter receiving the control signal and transmitting data to a destination device in accordance with the transmitter clock. The circuitry generally includes a clock alignment block receiving first and second periodic signals and providing a control signal in response thereto, a filter for first periodic signal information, and a logic circuit configured to combine the control signal and the filtered information, thereby providing an adjustment signal for the second periodic signal. The systems generally relate to those that include the present architecture and/or circuit. The method generally includes determining a phase difference between first and second periodic signals, one of the periodic signals being recovered from a data stream; adjusting the other periodic signal in response to the phase difference and filtered information from the recovered periodic signal; and transmitting the data stream in accordance with said adjusted periodic signal. The present invention advantageously eliminates a FIFO memory in the data path, thereby reducing transceiver latency and improving system performance.

摘要翻译： 用于促进数据通信和/或减少数据通信中的延迟的电路，架构，系统和方法。 该架构包括时钟恢复环路，其接收来自主机设备的数据并提供恢复的时钟信号，滤波器电路接收恢复的时钟信号信息，并提供响应于恢复的时钟信号信息和两个时钟信号调整发射机时钟的控制信号 以及接收控制信号并根据发射机时钟向目的地设备发送数据的发射机。 电路通常包括时钟对准块，其接收第一和第二周期信号并响应于此提供控制信号，用于第一周期性信号信息的滤波器以及被配置为组合控制信号和滤波信息的逻辑电路，由此提供调整 信号用于第二周期信号。 系统通常涉及包括本架构和/或电路的系统。 该方法通常包括确定第一和第二周期信号之间的相位差，从数据流中恢复一个周期信号; 响应于来自恢复的周期信号的相位差和滤波信息调整另一周期信号; 以及根据所述调整的周期信号发送数据流。 本发明有利地消除数据路径中的FIFO存储器，从而减少收发机等待时间并提高系统性能。

公开(公告)号：US07813536B2

公开(公告)日：2010-10-12

申请号：US11636475

申请日：2006-12-11

申请人： Hongfeng Ma ,  Qiang Di ,  Lei Wu ,  Honglei Fu ,  Longwei Mei ,  Liang Tian ,  Songmin Quan ,  Jun Zhang ,  Yan Kang

发明人： Hongfeng Ma ,  Qiang Di ,  Lei Wu ,  Honglei Fu ,  Longwei Mei ,  Liang Tian ,  Songmin Quan ,  Jun Zhang ,  Yan Kang

IPC分类号： G06K9/00

CPC分类号： G06K9/34 ,  A61B6/50 ,  G06K2209/05 ,  G06T7/0012 ,  G06T7/11 ,  G06T2207/10081 ,  G06T2207/30084

摘要： The present invention discloses an abdominal CT image measuring apparatus and method. The abdominal CT image measuring apparatus includes: an interface unit; a part recognizing unit and a characteristic data computing unit. The present invention can determine the specific region of the part under test with a little amount of computation, by registration and subtraction operation on the two-phase scan images. This is easy to be carried out in computers, thus the computing speed of the characteristic data can be guaranteed and the efficiency can be improved. By the recognizing of the kidney regions and the abdominal aorta region in the present invention, the glomerular filtration rates obtained by applying the key concept of the present invention to the image measuring of glomerular filtration rate can meet the clinical application requirements in both precision and speed.

摘要翻译： 本发明公开了一种腹部CT图像测量装置及方法。 腹部CT图像测量装置包括：接口单元; 部件识别单元和特征数据计算单元。 本发明可以通过对两相扫描图像进行配准和减法操作，通过少量的计算来确定待测零件的特定区域。 这在计算机中很容易实现，因此可以保证特征数据的计算速度并提高效率。 通过本发明的肾脏区域和腹主动脉区域的识别，通过将本发明的关键概念应用于肾小球滤过率的图像测定而获得的肾小球滤过率可以满足临床应用的精度和速度要求 。

公开(公告)号：US20100106486A1

公开(公告)日：2010-04-29

申请号：US12340632

申请日：2008-12-19

申请人： Xian-Sheng Hua ,  Lei Wu ,  Shipeng Li

发明人： Xian-Sheng Hua ,  Lei Wu ,  Shipeng Li

IPC分类号： G06F17/27 ,  G06K9/00

CPC分类号： G06K9/723 ,  G06K9/6226

摘要： Image-based semantic distance technique embodiments are presented that involve establishing a measure of an image-based semantic distance between semantic concepts. Generally, this entails respectively computing a semantic concept representation for each concept based on a collection of images associated with the concept. A degree of difference is then computed between two semantic concept representations to produce the aforementioned semantic distance measure for the pair of corresponding concepts.

摘要翻译： 提出了基于图像的语义距离技术实施例，其涉及建立语义概念之间基于图像的语义距离的度量。 通常，这需要基于与该概念相关联的图像的集合来分别计算每个概念的语义概念表示。 然后在两个语义概念表示之间计算差异程度，以产生用于该对相应概念的上述语义距离度量。