公开(公告)号：US20120185010A1

公开(公告)日：2012-07-19

申请号：US13353891

申请日：2012-01-19

申请人： Xiaohong Zhou ,  Lilian Kornet ,  Richard N.M. Cornelussen ,  Paul D. Ziegler ,  Robert Stadler ,  Eduardo Warman ,  Karen J. Kleckner ,  Lucy Nichols ,  Alberto Della Scala

发明人： Xiaohong Zhou ,  Lilian Kornet ,  Richard N.M. Cornelussen ,  Paul D. Ziegler ,  Robert Stadler ,  Eduardo Warman ,  Karen J. Kleckner ,  Lucy Nichols ,  Alberto Della Scala

IPC分类号： A61N1/365

CPC分类号： A61N1/36139 ,  A61N1/36053 ,  A61N1/36114 ,  A61N1/368 ,  A61N1/37235

摘要： The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.

公开(公告)号：US20120185009A1

公开(公告)日：2012-07-19

申请号：US13353861

申请日：2012-01-19

申请人： Lilian Kornet ,  Richard N.M. Cornelussen ,  Paul D. Ziegler ,  Xiaohong Zhou ,  Eduardo Warman ,  Karen J. Kleckner ,  Lucy Nichols ,  Alberto Della Scala

发明人： Lilian Kornet ,  Richard N.M. Cornelussen ,  Paul D. Ziegler ,  Xiaohong Zhou ,  Eduardo Warman ,  Karen J. Kleckner ,  Lucy Nichols ,  Alberto Della Scala

IPC分类号： A61N1/365

CPC分类号： A61N1/36114

摘要： The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.

公开(公告)号：US08706223B2

公开(公告)日：2014-04-22

申请号：US13353891

申请日：2012-01-19

申请人： Xiaohong Zhou ,  Lilian Kornet ,  Richard N. M. Cornelussen ,  Paul D. Ziegler ,  Robert Stadler ,  Eduardo Warman ,  Karen J. Kleckner ,  Lucy Nichols ,  Alberto Della Scala

发明人： Xiaohong Zhou ,  Lilian Kornet ,  Richard N. M. Cornelussen ,  Paul D. Ziegler ,  Robert Stadler ,  Eduardo Warman ,  Karen J. Kleckner ,  Lucy Nichols ,  Alberto Della Scala

IPC分类号： A61N1/04

CPC分类号： A61N1/36139 ,  A61N1/36053 ,  A61N1/36114 ,  A61N1/368 ,  A61N1/37235

摘要： The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.

摘要翻译： 本文的公开内容一般涉及使用迷走神经刺激治疗心脏病症的方法，还涉及用于进行这种治疗的系统和装置。 这样的方法可以包括监测患者的生理参数，检测心脏状况，以及向患者输送迷走神经刺激（例如，对迷走神经或具有副交感神经功能的神经元的电刺激）以治疗检测到的心脏状况。

公开(公告)号：US08725259B2

公开(公告)日：2014-05-13

申请号：US13353861

申请日：2012-01-19

申请人： Lilian Kornet ,  Richard N. M. Cornelussen ,  Paul D. Ziegler ,  Xiaohong Zhou ,  Eduardo Warman ,  Karen J. Kleckner ,  Lucy Nichols ,  Alberto Della Scala

发明人： Lilian Kornet ,  Richard N. M. Cornelussen ,  Paul D. Ziegler ,  Xiaohong Zhou ,  Eduardo Warman ,  Karen J. Kleckner ,  Lucy Nichols ,  Alberto Della Scala

IPC分类号： A61N1/365

CPC分类号： A61N1/36114

摘要： The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.

公开(公告)号：US08781582B2

公开(公告)日：2014-07-15

申请号：US13353802

申请日：2012-01-19

申请人： Paul D. Ziegler ,  Lilian Kornet ,  Xiaohong Zhou ,  Richard N. M. Cornelussen ,  Robert Stadler ,  Eduardo Warman ,  Karen J. Kleckner ,  Alberto Della Scala

发明人： Paul D. Ziegler ,  Lilian Kornet ,  Xiaohong Zhou ,  Richard N. M. Cornelussen ,  Robert Stadler ,  Eduardo Warman ,  Karen J. Kleckner ,  Alberto Della Scala

IPC分类号： A61N1/37

CPC分类号： A61N1/36139 ,  A61N1/36053 ,  A61N1/36114 ,  A61N1/3621 ,  A61N1/3627 ,  A61N1/36564 ,  A61N1/3682 ,  A61N1/3702 ,  A61N1/37235 ,  A61N1/3962

摘要： The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.

摘要翻译： 本文的公开内容一般涉及使用迷走神经刺激治疗心脏病症的方法，还涉及用于进行这种治疗的系统和装置。 这样的方法可以包括监测患者的生理参数，检测心脏状况，以及向患者输送迷走神经刺激（例如，对迷走神经或具有副交感神经功能的神经元的电刺激）以治疗检测到的心脏状况。

公开(公告)号：US08718763B2

公开(公告)日：2014-05-06

申请号：US13353824

申请日：2012-01-19

申请人： Xiaohong Zhou ,  Robert Stadler ,  Richard N. M. Cornelussen ,  Lilian Kornet ,  Paul D. Ziegler ,  Karen J. Kleckner ,  Alberto Della Scala

发明人： Xiaohong Zhou ,  Robert Stadler ,  Richard N. M. Cornelussen ,  Lilian Kornet ,  Paul D. Ziegler ,  Karen J. Kleckner ,  Alberto Della Scala

IPC分类号： A61N1/365

CPC分类号： A61N1/36114

摘要： The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.

公开(公告)号：US20120185007A1

公开(公告)日：2012-07-19

申请号：US13353802

申请日：2012-01-19

申请人： Paul D. Ziegler ,  Lillian Kornet ,  Xiaohong Zhou ,  Richard Cornelussen ,  Robert Stadler ,  Eduardo Warman ,  Karen J. Kleckner ,  Alberto Della Scala

发明人： Paul D. Ziegler ,  Lillian Kornet ,  Xiaohong Zhou ,  Richard Cornelussen ,  Robert Stadler ,  Eduardo Warman ,  Karen J. Kleckner ,  Alberto Della Scala

IPC分类号： A61N1/365

CPC分类号： A61N1/36139 ,  A61N1/36053 ,  A61N1/36114 ,  A61N1/3621 ,  A61N1/3627 ,  A61N1/36564 ,  A61N1/3682 ,  A61N1/3702 ,  A61N1/37235 ,  A61N1/3962

摘要： The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.

摘要翻译： 本文的公开内容一般涉及使用迷走神经刺激治疗心脏病症的方法，还涉及用于进行这种治疗的系统和装置。 这样的方法可以包括监测患者的生理参数，检测心脏状况，以及向患者输送迷走神经刺激（例如，对迷走神经或具有副交感神经功能的神经元的电刺激）以治疗检测到的心脏状况。

公开(公告)号：US20120185008A1

公开(公告)日：2012-07-19

申请号：US13353824

申请日：2012-01-19

申请人： Xiaohong Zhou ,  Robert Stadler ,  Richard Cornelussen ,  Lillian Kornet ,  Paul D. Ziegler ,  Karen J. Kleckner ,  Alberto Della Scala

发明人： Xiaohong Zhou ,  Robert Stadler ,  Richard Cornelussen ,  Lillian Kornet ,  Paul D. Ziegler ,  Karen J. Kleckner ,  Alberto Della Scala

IPC分类号： A61N1/365

CPC分类号： A61N1/36114

摘要： The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.

公开(公告)号：US08578118B2

公开(公告)日：2013-11-05

申请号：US11740362

申请日：2007-04-26

申请人： Karen J. Kleckner ,  Paul G. Krause ,  Traci K. Washburn ,  Melinda A. Kolstad

发明人： Karen J. Kleckner ,  Paul G. Krause ,  Traci K. Washburn ,  Melinda A. Kolstad

IPC分类号： G06F12/00

CPC分类号： G06F19/3418 ,  A61B5/0031 ,  A61B5/0422 ,  A61N1/3702 ,  G06F19/00 ,  G16H10/65

摘要： An implantable medical device and associated method store physiological data in response to detecting a physiological event. The medical device includes multiple first memory locations allocated to each of a number of physiological event types and a second single memory location allocated for storing entries of physiological signal data corresponding to each of the plurality of physiological event types.

摘要翻译： 可植入医疗装置和相关方法响应于检测到生理事件存储生理数据。 医疗设备包括分配给多个生理事件类型中的每一个的多个第一存储器位置和被分配用于存储对应于多个生理事件类型中的每一个的生理信号数据的条目的第二单个存储器位置。

公开(公告)号：US08521281B2

公开(公告)日：2013-08-27

申请号：US13273962

申请日：2011-10-14

申请人： Amisha S. Patel ,  Jian Cao ,  Karen J. Kleckner

发明人： Amisha S. Patel ,  Jian Cao ,  Karen J. Kleckner

IPC分类号： A61N1/362

CPC分类号： A61B5/046 ,  A61B5/0031 ,  A61B5/0464 ,  A61B5/0468 ,  A61N1/37 ,  A61N1/3962

摘要： The present disclosure is directed to the classification of cardiac episodes using an algorithm. In various examples, an episode classification algorithm evaluates electrogram signal data using a probabilistic ventricular oversensing algorithm. The algorithm may look at a plurality of factors weighing for and against a determination of ventricular oversensing. In some examples, the algorithm may also determine whether the cardiac episode includes atrial sensing issues.

摘要翻译： 本公开涉及使用算法对心脏发作的分类。 在各种示例中，发作分类算法使用概率性心室过敏算法来评估电描记图信号数据。 该算法可以考虑多个因素来衡量和抵抗心室过敏的确定。 在一些示例中，算法还可以确定心脏发作是否包括心房感测问题。