Bidirectional promoters and methods related thereto
    5.
    发明授权
    Bidirectional promoters and methods related thereto 失效
    双向启动子及其相关方法

    公开(公告)号:US06388170B1

    公开(公告)日:2002-05-14

    申请号:US09545244

    申请日:2000-04-07

    IPC分类号: C12Q168

    摘要: The present invention comprises artificial nucleic acid constructs comprising a bidirectional promoter having minimal promoter and a common promoter, wherein said minimal promoters is operably linked to said common promoter, in opposite orientation to said common promoter, and 5′ to said common promoter. Those artificial nucleic acid constructs, wherein said bidirectional promoter further comprises at least one gene operably linked to said minimal promoter and said common promoter are preferred.

    摘要翻译: 本发明包括人造核酸构建体,其包含具有最小启动子和共同启动子的双向启动子,其中所述最小启动子以与所述共同启动子相反的方向与所述共同启动子可操作地连接,5'与所述共同启动子有效连接。 那些人造核酸构建体,其中所述双向启动子还包含与所述最小启动子可操作地连接的至少一个基因,所述共同启动子是优选的。