公开(公告)号：US09061688B2

公开(公告)日：2015-06-23

申请号：US13884271

申请日：2012-07-27

申请人： Linghan Yue ,  Shuang Yang ,  Baichuan He ,  Lei Yu ,  Zhigang Li ,  Tianjun Zhao ,  Yong Fu ,  Shengkun Wang

发明人： Linghan Yue ,  Shuang Yang ,  Baichuan He ,  Lei Yu ,  Zhigang Li ,  Tianjun Zhao ,  Yong Fu ,  Shengkun Wang

IPC分类号： B61D7/00 ,  B61D7/22 ,  B61D7/02 ,  B61D7/18

CPC分类号： B61D7/22 ,  B61D7/02 ,  B61D7/18

摘要： The present application provides a bottom door device and a hopper car, the bottom door device includes a first bottom door and a second bottom door, the first bottom door includes a first door end plate and a first bottom door plate which are fixedly connected, the second bottom door includes a second door end plate and a second bottom door plate which are fixedly connected, and a labyrinth seal is formed between the first bottom door plate and the second bottom door plate. By using a labyrinth seal to replace the overlapping sealing in the prior art, the bottom door device and the hopper car provided by the present application can still meet the sealing requirement on the premise that the two bottom door plates can be closed without complying with any specific order, thereby optimizing the structure of the bottom door device in the prior art.

摘要翻译： 本申请提供了一种底门装置和料斗车，底门装置包括第一底门和第二底门，第一底门包括固定连接的第一门端板和第一底门板， 第二底门包括固定连接的第二门端板和第二底门板，并且在第一底门板和第二底门板之间形成迷宫式密封。 通过使用迷宫式密封件来替代现有技术中的重叠密封，本申请提供的底部门装置和料斗车厢可以在两个底部门板可以关闭而不符合任何方式的情况下仍能满足密封要求 从而优化现有技术中的底门装置的结构。

公开(公告)号：US08939088B2

公开(公告)日：2015-01-27

申请号：US13876842

申请日：2012-08-28

申请人： Linghan Yue ,  Tianjun Zhao ,  Baichuan He ,  Shuang Yang ,  Lei Yu

发明人： Linghan Yue ,  Tianjun Zhao ,  Baichuan He ,  Shuang Yang ,  Lei Yu

IPC分类号： B61D7/24 ,  B61D7/28 ,  B61D7/18 ,  F16H21/44 ,  B61D7/02 ,  E05F15/02

CPC分类号： F16H21/44 ,  B61D7/02 ,  B61D7/18 ,  B61D7/28 ,  E05F15/47 ,  Y10T74/1892

摘要： A bottom door opening-closing mechanism includes a first connecting rod, a second connecting rod, a swing rod, a bottom door opening-closing drive cylinder and a transmission shaft. The swing rod is hinged to the second connecting rod and the piston rod of the bottom door opening-closing drive cylinder. One end of the first connecting rod is hinged to the second connecting rod, and the transmission shaft is connected to the second connecting rod. The cylinder body of the bottom door opening-closing drive cylinder is fixedly connected with a first locking hook, and the swing rod is fixedly connected with a second locking hook which can be caught by the first locking hook. A bottom door device and a drop-bottom hopper car are further provided. In the present invention, the first locking hook and the second locking hook are caught with each other to achieve a secondary locking. Such an arrangement has some advantages such as a simple structure and low manufacture and maintenance costs. Further, a secondary locking may be achieved while closing the bottom door only by controlling the bottom door opening-closing drive cylinder, so that the complexity of the control system is reduced.

摘要翻译： 底门开闭机构包括第一连杆，第二连杆，摆杆，底门开闭驱动气缸和传动轴。 摆杆铰接到底门开闭驱动气缸的第二连杆和活塞杆上。 第一连杆的一端铰接到第二连杆上，传动轴连接到第二连杆上。 底门开闭驱动气缸的缸体与第一锁定钩固定连接，摆杆与第一锁定钩卡住的第二锁定钩固定连接。 还提供了底部门装置和底部底部漏斗车。 在本发明中，第一锁定钩和第二锁定钩被彼此卡住以实现二次锁定。 这种布置具有结构简单，制造和维护成本低等优点。 此外，只有通过控制底门打开 - 关闭驱动气缸才可以在关闭底门的同时实现辅助锁定，从而降低了控制系统的复杂性。

公开(公告)号：US20140216299A1

公开(公告)日：2014-08-07

申请号：US13876842

申请日：2012-08-28

申请人： Linghan Yue ,  Tianjun Zhao ,  Baichuan He ,  Shuang Yang ,  Lei Yu

发明人： Linghan Yue ,  Tianjun Zhao ,  Baichuan He ,  Shuang Yang ,  Lei Yu

IPC分类号： F16H21/44 ,  B61D7/02 ,  E05F15/02

CPC分类号： F16H21/44 ,  B61D7/02 ,  B61D7/18 ,  B61D7/28 ,  E05F15/47 ,  Y10T74/1892

摘要： A bottom door opening-closing mechanism includes a first connecting rod, a second connecting rod, a swing rod, a bottom door opening-closing drive cylinder and a transmission shaft. The swing rod is hinged to the second connecting rod and the piston rod of the bottom door opening-closing drive cylinder. One end of the first connecting rod is hinged to the second connecting rod, and the transmission shaft is connected to the second connecting rod. The cylinder body of the bottom door opening-closing drive cylinder is fixedly connected with a first locking hook, and the swing rod is fixedly connected with a second locking hook which can be caught by the first locking hook. A bottom door device and a drop-bottom hopper car are further provided. In the present invention, the first locking hook and the second locking hook are caught with each other to achieve a secondary locking. Such an arrangement has some advantages such as a simple structure and low manufacture and maintenance costs. Further, a secondary locking may be achieved while closing the bottom door only by controlling the bottom door opening-closing drive cylinder, so that the complexity of the control system is reduced.

摘要翻译： 底门开闭机构包括第一连杆，第二连杆，摆杆，底门开闭驱动气缸和传动轴。 摆杆铰接到底门开闭驱动气缸的第二连杆和活塞杆上。 第一连杆的一端铰接到第二连杆上，传动轴连接到第二连杆上。 底门开闭驱动气缸的缸体与第一锁定钩固定连接，摆杆与第一锁定钩卡住的第二锁定钩固定连接。 还提供了底部门装置和底部底部漏斗车。 在本发明中，第一锁定钩和第二锁定钩被彼此卡住以实现二次锁定。 这种布置具有结构简单，制造和维护成本低等优点。 此外，只有通过控制底门打开 - 关闭驱动气缸才可以在关闭底门的同时实现辅助锁定，从而降低了控制系统的复杂性。

公开(公告)号：US08647278B2

公开(公告)日：2014-02-11

申请号：US13280778

申请日：2011-10-25

申请人： Zhong Ji ,  Li Yang ,  Shuang Yang ,  Mingxi Zhao

发明人： Zhong Ji ,  Li Yang ,  Shuang Yang ,  Mingxi Zhao

IPC分类号： A61B8/00

CPC分类号： A61B8/04 ,  A61B5/026 ,  A61B5/031 ,  A61B5/04842 ,  A61B5/7246 ,  A61B8/0816 ,  A61B8/488 ,  A61B8/5223 ,  A61B2562/0215

摘要： Disclosed embodiments include a system and a method for determining intracranial pressure (ICP) of a subject that comprises: (a) applying transcranial Doppler (TCD) to determine the middle cerebral artery (MCA) velocity of the subject and estimating changes in the ICP continuously based on a functional mapping that relates arterial blood pressure (ABP) and cerebral blood flow velocity (CBFV) to ICP, resulting in an estimated ICP trend; (b) generating a flash visual evoked potential (FVEP) on the subject, processing a detected FVEP signal and obtaining an estimated ICP; and (c) combining the estimated ICP trend from TCD CBFV and ABP with the estimated ICP obtained by signal processing of the detected FVEP signal to periodically correct the trend and obtain a non-invasive measure of ICP.

摘要翻译： 公开的实施例包括用于确定受试者的颅内压（ICP）的系统和方法，其包括：（a）施加经颅多普勒（TCD）以确定受试者的中脑动脉（MCA）速度并连续估计ICP的变化 基于将动脉血压（ABP）和脑血流速度（CBFV）与ICP相关的功能映射，导致估计的ICP趋势; （b）在对象上产生闪光视觉诱发电位（FVEP），处理检测到的FVEP信号并获得估计的ICP; 和（c）将来自TCD CBFV和ABP的估计ICP趋势与通过检测到的FVEP信号的信号处理获得的估计的ICP结合，以周期性地校正趋势并获得ICP的非侵入性测量。

公开(公告)号：US20110296052A1

公开(公告)日：2011-12-01

申请号：US12790433

申请日：2010-05-28

申请人： Chuanxiong Guo ,  Guohan Lv ,  Shuang Yang ,  Jiahe Helen Wang

发明人： Chuanxiong Guo ,  Guohan Lv ,  Shuang Yang ,  Jiahe Helen Wang

IPC分类号： G06F15/16 ,  G06F9/455

CPC分类号： H04L45/34 ,  G06F9/5077 ,  H04L45/00

摘要： A virtual data center allocation architecture with bandwidth guarantees that provides for the creation of multiple virtual data centers from a single physical infrastructure. The virtual data center allocation is accomplished in three steps. First, clusters are created from the servers in the physical infrastructure. Second, a bipartite graph is built to map the virtual machines to the servers located in a particular cluster and finally a path is calculated between two virtual machines. The virtual data centers may be dynamically expanded or contracted based on changing bandwidth guarantees.

摘要翻译： 具有带宽的虚拟数据中心分配架构保证了从单一物理基础设施创建多个虚拟数据中心。 虚拟数据中心分配通过三个步骤完成。 首先，集群是从物理基础架构中的服务器创建的。 第二，构建了一个二分图，将虚拟机映射到位于特定集群中的服务器，最后在两个虚拟机之间计算路径。 可以基于不断变化的带宽保证来动态扩展或缩小虚拟数据中心。

公开(公告)号：US08667171B2

公开(公告)日：2014-03-04

申请号：US12790433

申请日：2010-05-28

申请人： Chuanxiong Guo ,  Guohan Lv ,  Shuang Yang ,  Jiahe Helen Wang

发明人： Chuanxiong Guo ,  Guohan Lv ,  Shuang Yang ,  Jiahe Helen Wang

IPC分类号： G06F15/16 ,  G06F12/00

CPC分类号： H04L45/34 ,  G06F9/5077 ,  H04L45/00

摘要： A virtual data center allocation architecture with bandwidth guarantees that provides for the creation of multiple virtual data centers from a single physical infrastructure. The virtual data center allocation is accomplished in three steps. First, clusters are created from the servers in the physical infrastructure. Second, a bipartite graph is built to map the virtual machines to the servers located in a particular cluster and finally a path is calculated between two virtual machines. The virtual data centers may be dynamically expanded or contracted based on changing bandwidth guarantees.

摘要翻译： 具有带宽的虚拟数据中心分配架构保证了从单一物理基础设施创建多个虚拟数据中心。 虚拟数据中心分配通过三个步骤完成。 首先，集群是从物理基础架构中的服务器创建的。 第二，构建了一个二分图，将虚拟机映射到位于特定集群中的服务器，最后在两个虚拟机之间计算路径。 可以基于不断变化的带宽保证来动态扩展或缩小虚拟数据中心。

公开(公告)号：US20140135235A1

公开(公告)日：2014-05-15

申请号：US14124288

申请日：2012-06-06

申请人： Hui Zhang ,  Shuang Yang

发明人： Hui Zhang ,  Shuang Yang

IPC分类号： G01N33/68

CPC分类号： G01N33/6842 ,  C07B2200/11 ,  C07K1/22 ,  C07K9/00 ,  C07K14/4725 ,  C08B37/00 ,  C08B37/0003 ,  C08H1/00 ,  C40B40/12 ,  C40B50/18 ,  G01N2400/10 ,  Y10T436/143333

摘要： Highly specific and novel methods for reversible hydrazone solid-phase extraction (rHSPE) are provided for glycan or glycopeptide isolation from proteins, peptides, and other contaminants for glycan and glycopeptide analysis. Glycans or glycopeptides in complex mixtures can be conjugated onto solid support or affinity or chemical tags via reversible hydrazone bond. The conjugation methods of the present invention are chemically specific and provide unique means for the removal of other non-glycan containing molecules in the complex sample before the glycans or glycopeptides are hydrolyzed and recovered for analysis. The hydrazone formation and hydrolysis of the novel methods allows for the analysis of glycans and glycopeptides. The hydrazide coating on the solid-phase surfaces are useful for surface glycan capture and on target glycan analysis. Uses of the information generated by the inventive methods for diagnosis and treatment are also disclosed.

摘要翻译： 提供用于可逆腙固相萃取（rHSPE）的高度特异性和新颖的方法，用于从聚糖和糖肽分析的蛋白质，肽和其他污染物中分离聚糖或糖肽。 复合混合物中的糖或糖肽可以通过可逆的腙键缀合到固体支持物或亲和力或化学标签上。 本发明的缀合方法是化学特异性的，并且在聚糖或糖肽被水解和回收用于分析之前提供用于去除复合物样品中其它非聚糖聚合分子的独特手段。 腙的形成和水解的新方法允许分析聚糖和糖肽。 固相表面上的酰肼涂层可用于表面聚糖捕获和目标聚糖分析。 还公开了通过本发明的诊断和治疗方法产生的信息的使用。

公开(公告)号：US20110029516A1

公开(公告)日：2011-02-03

申请号：US12512859

申请日：2009-07-30

申请人： Qing Chang ,  Keiichiro Suzuki ,  Harini Sridharan ,  Prashant Kamani ,  Aleksandr Lyamtsev ,  Mingyang Zhao ,  Aditee Kumthekar ,  Ashutosh Galande ,  Charles Ainslie ,  Staya Priya Hotani ,  Reshma Mehta ,  Tho Van Nguyen ,  Yuan Gao ,  Li Yang ,  Jin Wu ,  Shuang Yang ,  Smridh Thapar

发明人： Qing Chang ,  Keiichiro Suzuki ,  Harini Sridharan ,  Prashant Kamani ,  Aleksandr Lyamtsev ,  Mingyang Zhao ,  Aditee Kumthekar ,  Ashutosh Galande ,  Charles Ainslie ,  Staya Priya Hotani ,  Reshma Mehta ,  Tho Van Nguyen ,  Yuan Gao ,  Li Yang ,  Jin Wu ,  Shuang Yang ,  Smridh Thapar

IPC分类号： G06F17/30

CPC分类号： G06F16/957

摘要： A web site usage pattern insight platform may be provided. User behaviors associated with web page requests, including search queries, may be captured and analyzed to provide usage pattern insights. The pattern insights may be aggregated across a plurality of users and may be used to provide recommendations for improving a system that hosts the web pages.

摘要翻译： 可以提供网站使用模式洞察平台。 可以捕获和分析与网页请求（包括搜索查询）相关联的用户行为，以提供使用模式洞察。 模式洞察可以在多个用户之间聚合，并且可以用于提供用于改进托管网页的系统的建议。