Dilatation catheter having a random copolymer balloon
    1.
    发明授权
    Dilatation catheter having a random copolymer balloon 失效
    具有无规共聚球囊的扩张导管

    公开(公告)号:US5330428A

    公开(公告)日:1994-07-19

    申请号:US699926

    申请日:1991-05-14

    IPC分类号: A61F2/958 A61M25/00

    CPC分类号: A61M25/1029 A61M25/10

    摘要: The present invention provides a dilatation catheter which includes a balloon having at least one layer of a thermoplastic material consisting essentially of a random copolymer made from dimethyl terephthalate dimethyl isophthalate and ethylene glycol. These balloons are particular suited for use on dilatation catheters used for percutaneous transluminal coronary angioplasty.

    摘要翻译: 本发明提供了一种扩张导管,其包括具有至少一层热塑性材料的气囊,所述热塑性材料主要由由对苯二甲酸二甲酯和间苯二甲酸二甲酯形成的无规共聚物组成。 这些气球特别适用于用于经皮腔内冠状动脉血管成形术的扩张导管。

    RENAL ABLATION ELECTRODE WITH FORCE-ACTIVATABLE CONDUCTION APPARATUS
    2.
    发明申请
    RENAL ABLATION ELECTRODE WITH FORCE-ACTIVATABLE CONDUCTION APPARATUS 有权
    具有强力导联装置的RENAL ABLATION ELECTRODE

    公开(公告)号:US20120172870A1

    公开(公告)日:2012-07-05

    申请号:US13303130

    申请日:2011-11-22

    IPC分类号: A61B18/18

    摘要: An electrode is provided at a distal end of a catheter and dimensioned for deployment within a renal artery. A deformable cover of the electrode incorporates a force-activatable conduction apparatus. The cover is configured to conduct electrical energy only through a region or regions of the cover subject to deformation due to contact with a wall of the target vessel. The electrical energy is sufficient to ablate perivascular renal nerves proximate the deformed region or regions of the electrode cover. The cover is configured to prevent conduction of electrical energy through the cover in the absence of a deformation force applied to the cover.

    摘要翻译: 在导管的远端设置电极,其尺寸适于在肾动脉内展开。 电极的可变形的外壳包含一个力可激活的传导装置。 盖被配置成仅通过与目标容器的壁接触而受到变形的区域或区域传导电能。 电能足以消除靠近变形区域或电极盖的区域的血管周围肾神经。 盖被配置成在没有施加到盖的变形力的情况下防止电能通过盖的传导。

    Minimally Invasive Access for Renal Nerve Ablation
    4.
    发明申请
    Minimally Invasive Access for Renal Nerve Ablation 有权
    微创获取肾神经消融

    公开(公告)号:US20120123303A1

    公开(公告)日:2012-05-17

    申请号:US13243134

    申请日:2011-09-23

    摘要: An elongated flexible medical device is inserted into a patient's body via a natural orifice, and advanced through the natural orifice to a location proximate innervated tissue that influences renal sympathetic nerve activity. The medical device can be advanced into a body organ and to a location within the organ proximate the innervated tissue. The organ may comprise an organ of the gastrointestinal tract or urinary tract. The medical device may be advanced through and beyond an access hole in a wall of the organ, and situated at a location proximate the innervated tissue. One or both of imaging and ablation energy is delivered from a distal end of the medical device to the innervated tissue. Innervated renal tissue can be ablated using various forms of energy, including RF energy, ultrasound energy, optical energy, and thermal energy.

    摘要翻译: 细长的柔性医疗装置通过自然孔插入患者体内,并通过自然孔推进到影响肾交感神经活动的靠近神经组织的位置。 医疗装置可以进入身体器官和靠近神经组织的器官内的位置。 器官可以包括胃肠道或泌尿道的器官。 医疗装置可以前进穿过器官壁中的进入孔并且位于邻近神经组织的位置处。 成像和消融能量中的一个或两个从医疗装置的远端传送到神经组织。 可以使用各种形式的能量消融内源性肾组织,包括射频能量,超声能量,光能和热能。

    Support structure/membrane composite medical device
    7.
    发明授权
    Support structure/membrane composite medical device 失效
    支撑结构/膜复合医疗器械

    公开(公告)号:US06699276B2

    公开(公告)日:2004-03-02

    申请号:US09505158

    申请日:2000-02-16

    IPC分类号: A61F206

    摘要: The present invention relates to a support structure/membrane composite device which includes a support structure, such as a radially expandable stent, a porous non-textile polymeric membrane adjacent to said stent and a thermoplastic anchor means attaching said stent to said porous non-textile polymeric membrane. The porous non-textile polymeric membrane is preferably made from expandable fluoropolymer materials. The anchoring means is a thermoplastic material which is dissolvable at the interface between the support structure and membrane by a suitable solvent which wets the membrane surface and deposits the thermoplastic material within the pores of the membrane. Methods of preparing the device are also disclosed.

    摘要翻译: 本发明涉及一种支撑结构/膜复合装置,其包括诸如径向可扩张的支架的支撑结构,与所述支架相邻的多孔非纺织聚合物膜和将所述支架附接到所述多孔非纺织物的热塑性锚定装置 聚合物膜。 多孔非纺织聚合物膜优选由可膨胀的含氟聚合物材料制成。 锚定装置是一种热塑性材料,其可通过润湿膜表面并将热塑性材料沉积在膜的孔内的合适溶剂在溶液在支撑结构和膜之间的界面处被溶解。 还公开了制备该装置的方法。

    Covered stent
    8.
    发明授权
    Covered stent 失效
    覆盖支架

    公开(公告)号:US5824046A

    公开(公告)日:1998-10-20

    申请号:US720091

    申请日:1996-09-27

    IPC分类号: A61F2/92 A61F2/06 A61F2/04

    摘要: A composite intraluminal device is deployable within a body vessel. The composite device includes an elongate radially expandable tubular stent having an interior luminal surface and an opposed exterior surface extending along a longitudinal stent axis. A stent cover is formed of unsintered ePTFE which is expandable. The stent cover is positioned about the stent so as to permit expansion of the cover upon the radial expansion of the stent.

    摘要翻译: 复合腔内装置可在体内容器内部署。 复合装置包括细长的可径向扩张的管状支架,其具有内部管腔表面和沿纵向支架轴线延伸的相对的外表面。 支架盖由可膨胀的未烧结的ePTFE形成。 支架盖围绕支架定位,以便允许在支架的径向膨胀时膨胀盖。

    Renal ablation electrode with force-activatable conduction apparatus
    9.
    发明授权
    Renal ablation electrode with force-activatable conduction apparatus 有权
    具有力激活传导装置的肾消融电极

    公开(公告)号:US09023034B2

    公开(公告)日:2015-05-05

    申请号:US13303130

    申请日:2011-11-22

    摘要: An electrode is provided at a distal end of a catheter and dimensioned for deployment within a renal artery. A deformable cover of the electrode incorporates a force-activatable conduction apparatus. The cover is configured to conduct electrical energy only through a region or regions of the cover subject to deformation due to contact with a wall of the target vessel. The electrical energy is sufficient to ablate perivascular renal nerves proximate the deformed region or regions of the electrode cover. The cover is configured to prevent conduction of electrical energy through the cover in the absence of a deformation force applied to the cover.

    摘要翻译: 在导管的远端设置电极,其尺寸适于在肾动脉内展开。 电极的可变形的外壳包含一个力可激活的传导装置。 盖被配置成仅通过与目标容器的壁接触而受到变形的区域或区域传导电能。 电能足以消除靠近变形区域或电极盖的区域的血管周围肾神经。 盖被配置成在没有施加到盖的变形力的情况下防止电能通过盖的传导。

    MAGNETIC PARTICLES FOR DELIVERING THERAPEUTIC AGENT TO A TARGET LOCATION
    10.
    发明申请
    MAGNETIC PARTICLES FOR DELIVERING THERAPEUTIC AGENT TO A TARGET LOCATION 有权
    用于将治疗药物递送至目标位置的磁性颗粒

    公开(公告)号:US20100269838A1

    公开(公告)日:2010-10-28

    申请号:US12765369

    申请日:2010-04-22

    IPC分类号: A61B19/00

    摘要: A system for delivering therapeutic agent to a target location in a body in accordance with one embodiment is provided comprising a plurality of magnetic particles, each magnetic particle carrying a therapeutic agent, and a magnetic device for attracting the magnetic particles to a target location. The magnetic particles may be delivered by a catheter into a blood vessel upstream from the target location so that they travel toward the target location. A method for delivering therapeutic agent to a target location in a body in accordance with another embodiment comprises providing a plurality of magnetic particles, each magnetic particle carrying a therapeutic agent, placing a magnetic device in a position to attract the magnetic particles to a target location, and allowing the magnetic particles to infuse the target location by the attraction of the magnetic particles to the magnetic device. The therapeutic agent may comprises a therapeutic agent for preventing or treating reperfusion injury, and the step of providing the plurality of magnetic particles may comprise delivering the plurality of magnetic particles through a blood vessel.

    摘要翻译: 提供了根据一个实施例的用于将治疗剂递送到身体中的目标位置的系统,其包括多个磁性颗粒,每个携带治疗剂的磁性颗粒和用于将磁性颗粒吸引到目标位置的磁性装置。 磁性颗粒可以通过导管输送到目标位置上游的血管中,使得它们朝向目标位置行进。 根据另一实施例的用于将治疗剂递送到身体中的目标位置的方法包括提供多个磁性颗粒,每个磁性颗粒携带治疗剂,将磁性装置放置在将磁性颗粒吸引到目标位置的位置 ,并且允许磁性颗粒通过磁性颗粒吸引到磁性装置来注入目标位置。 治疗剂可以包括用于预防或治疗再灌注损伤的治疗剂,并且提供多个磁性颗粒的步骤可以包括通过血管递送多个磁性颗粒。