-
公开(公告)号:US20110165632A1
公开(公告)日:2011-07-07
申请号:US12993341
申请日:2009-05-18
申请人: Louis-Charles Campeau , John Y. Chung , Danny Gauvreau , Melina Girardin-Rondeau , Gregory Hughes , Kevin M. Maloney , Christophe Mellon , Jeffrey C. Moore , Paul O'Shea , Stephane Quellet
发明人: Louis-Charles Campeau , John Y. Chung , Danny Gauvreau , Melina Girardin-Rondeau , Gregory Hughes , Kevin M. Maloney , Christophe Mellon , Jeffrey C. Moore , Paul O'Shea , Stephane Quellet
IPC分类号: C12P17/16 , C07D401/14
CPC分类号: C07D401/14 , C07D233/96 , C07D401/12
摘要: The present invention is directed to processes for preparing a pyridyl piperidine compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved.
摘要翻译: 本发明涉及制备食欲肽受体拮抗剂的吡啶基哌啶化合物的方法,其可用于治疗或预防涉及食欲肽受体的神经和精神疾病及疾病。
-
公开(公告)号:US08674093B2
公开(公告)日:2014-03-18
申请号:US12993341
申请日:2009-05-18
申请人: Louis-Charles Campeau , John Y. Chung , Danny Gauvreau , Melina Girardin-Rondeau , Gregory Hughes , Kevin M. Maloney , Christophe Mellon , Jeffrey C. Moore , Paul O'Shea , Stephane Ouellet
发明人: Louis-Charles Campeau , John Y. Chung , Danny Gauvreau , Melina Girardin-Rondeau , Gregory Hughes , Kevin M. Maloney , Christophe Mellon , Jeffrey C. Moore , Paul O'Shea , Stephane Ouellet
IPC分类号: C07D401/12 , C07D401/14 , C07D403/14 , C07D239/24
CPC分类号: C07D401/14 , C07D233/96 , C07D401/12
摘要: The present invention is directed to processes for preparing a pyridyl piperidine compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved.
摘要翻译: 本发明涉及制备食欲肽受体拮抗剂的吡啶基哌啶化合物的方法,其可用于治疗或预防涉及食欲肽受体的神经和精神疾病及疾病。
-
公开(公告)号:US5821937A
公开(公告)日:1998-10-13
申请号:US695608
申请日:1996-08-12
CPC分类号: H04L41/145 , H04L41/22 , H04L41/12
摘要: A method for designing networks including auditing a network to discover a present network configuration, creating a network design sheet from the discovered network configuration, placing device icons representing intelligent device objects on the network design sheet, selecting a media type representing an intelligent media object, and connecting the media type to a first one of the device icons. The method further includes validating the connection to the first one of the device icons.
摘要翻译: 一种用于设计网络的方法,包括审核网络以发现当前网络配置,从所发现的网络配置创建网络设计表,将表示智能设备对象的设备图标放置在网络设计表上,选择表示智能媒体对象的媒体类型, 并将媒体类型连接到第一个设备图标。 该方法还包括验证与第一个设备图标的连接。
-
公开(公告)号:US5831610A
公开(公告)日:1998-11-03
申请号:US606327
申请日:1996-02-23
CPC分类号: H04L41/12 , H04L41/145 , H04L41/22
摘要: A method for designing networks including placing device icons representing intelligent device objects on a network design sheet, selecting a media type representing an intelligent media object, and connecting the media type to a first one of the device icons. The method further includes validating the connection to the first one of the device icons.
摘要翻译: 一种用于设计网络的方法,包括将表示智能设备对象的设备图标放置在网络设计表上,选择表示智能媒体对象的媒体类型,以及将媒体类型连接到设备图标中的第一个。 该方法还包括验证与第一个设备图标的连接。
-
公开(公告)号:US20140242645A1
公开(公告)日:2014-08-28
申请号:US14354161
申请日:2012-10-22
申请人: John Y.L. Chung , Kevin Campos , Edward Cleator , Robert F. Dunn , Andrew Gibson , R Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
发明人: John Y.L. Chung , Kevin Campos , Edward Cleator , Robert F. Dunn , Andrew Gibson , R Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
IPC分类号: C07D207/09 , C12P17/10
CPC分类号: C07D207/09 , C07D207/08 , C12P17/10
摘要: The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions.
摘要翻译: 本发明涉及通过多步反应制备式I-11化合物的方法。
-
公开(公告)号:US20100234604A1
公开(公告)日:2010-09-16
申请号:US12722711
申请日:2010-03-12
申请人: Xin Linghu , Kathleen Linn , Kevin M. Maloney , Mark McLaughlin , Gang Qian
发明人: Xin Linghu , Kathleen Linn , Kevin M. Maloney , Mark McLaughlin , Gang Qian
IPC分类号: C07D211/20 , C07D213/62
CPC分类号: C07D213/79 , C07D211/24
摘要: The present invention relates to novel substituted aryl sulfone intermediates and processes for preparing the same. An aspect of this invention relates to a process for making substituted aryl sulfone intermediates utilizing a one-pot deacylation-carbon/sulfur bond formation step. The invention also relates to a process for preparing intermediates that are used to make the compounds of formula I. Some of the advantages of the present invention include manufacturing flexibility and efficiency, high yield synthesis using a one pot deacylation and carbon-sulfur bond formation step of a thioester intermediate and the like. This and other aspects of the invention will be realized upon review of the specification as a whole.
-
公开(公告)号:US20100234603A1
公开(公告)日:2010-09-16
申请号:US12722779
申请日:2010-03-12
申请人: Xin Linghu , Kathleen Linn , Kevin M. Maloney , Mark McLaughlin , Gang Qian
发明人: Xin Linghu , Kathleen Linn , Kevin M. Maloney , Mark McLaughlin , Gang Qian
IPC分类号: C07D211/14
CPC分类号: C07D401/04 , C07D211/24 , C07D213/79
摘要: The present invention relates to novel substituted aryl sulfone intermediates and processes for preparing the same. An aspect of this invention relates to a process for making substituted aryl sulfone intermediates utilizing a one-pot deacylation-carbon/sulfur bond formation step. The invention also relates to a process for preparing intermediates that are used to make the compounds of formula I. Some of the advantages of the present invention include manufacturing flexibility and efficiency, high yield synthesis using a one pot deacylation and carbon-sulfur bond formation step of a thioester intermediate and the like. This and other aspects of the invention will be realized upon review of the specification as a whole.
摘要翻译: 本发明涉及新型取代的芳基砜中间体及其制备方法。 本发明的一个方面涉及利用一锅脱酰基 - 碳/硫键形成步骤制备取代的芳基砜中间体的方法。 本发明还涉及用于制备式I化合物的中间体的方法。本发明的一些优点包括使用一锅脱酰和碳 - 硫键形成步骤制备柔性和效率,高产率合成 的硫酯中间体等。 本发明的这个和其它方面将在整个规范审查之后实现。
-
公开(公告)号:US06229540B1
公开(公告)日:2001-05-08
申请号:US09170838
申请日:1998-10-13
IPC分类号: G66F1300
CPC分类号: H04L41/145 , H04L41/12 , H04L41/22
摘要: A method for designing networks including auditing a network to discover a present network configuration, creating a network design sheet from the discovered network configuration, placing device icons representing intelligent device objects on the network design sheet, selecting a media type representing an intelligent media object, and connecting the media type to a first one of the device icons. The method further includes validating the connection to the first one of the device icons.
摘要翻译: 一种用于设计网络的方法,包括审核网络以发现当前网络配置,从所发现的网络配置创建网络设计表,将表示智能设备对象的设备图标放置在网络设计表上,选择表示智能媒体对象的媒体类型, 并将媒体类型连接到第一个设备图标。 该方法还包括验证与第一个设备图标的连接。
-
-
-
-
-
-
-