公开(公告)号：US20250099741A1

公开(公告)日：2025-03-27

申请号：US18958196

申请日：2024-11-25

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M60/422 ,  A61B5/0215 ,  A61B5/283 ,  A61M60/13 ,  A61M60/135 ,  A61M60/148 ,  A61M60/174 ,  A61M60/237 ,  A61M60/40 ,  A61M60/414 ,  A61M60/419 ,  A61M60/50 ,  A61M60/531 ,  A61M60/538 ,  A61M60/554 ,  A61M60/806 ,  A61M60/818 ,  A61M60/824 ,  A61M60/825 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

Abstract: Apparatus and methods are described including deploying a pump head of a left-ventricular assist device in a subject's left ventricle. The pump head includes an axial shaft, and a radially-expandable impeller coupled to the axial shaft. A proximal radial bearing is disposed around the axial shaft proximally to the impeller, and a distal radial bearing is disposed around the axial shaft distally to the impeller. The interface between the axial shaft and the distal radial bearing is purged, by pumping purging fluid into a purging-fluid lumen defined by the left-ventricular assist device. Other applications are also described.

公开(公告)号：US20220088368A1

公开(公告)日：2022-03-24

申请号：US17528015

申请日：2021-11-16

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M60/422 ,  A61B5/0215 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00 ,  A61B5/283 ,  A61M60/40 ,  A61M60/50 ,  A61M60/135 ,  A61M60/148 ,  A61M60/205 ,  A61M60/414 ,  A61M60/419 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896

Abstract: Apparatus and methods are described including placing, into a subject's body, a blood-pump tube, with an impeller disposed within the blood-pump tube. At least one blood-pressure-measurement element extends to at least an outer surface of the blood-pump tube, such that the distal end of the blood-pressure-measurement element is in direct fluid communication with a bloodstream of the subject outside the blood-pump tube at a location that is proximal to blood-inlet opening(s) defined by the blood-pump tube. Blood is pumped through the blood-pump tube, using the impeller. Pressure of the bloodstream of the subject outside the blood-pump tube is measured by measuring blood pressure at the distal end of the left-ventricular blood-pressure-measurement element. Other applications are also described.

公开(公告)号：US20190209758A1

公开(公告)日：2019-07-11

申请号：US16281264

申请日：2019-02-21

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/12 ,  A61M1/10

CPC classification number: A61M1/122 ,  A61B5/0215 ,  A61B5/042 ,  A61M1/1008 ,  A61M1/1013 ,  A61M1/102 ,  A61M1/1031 ,  A61M1/1034 ,  A61M1/1036 ,  A61M1/1086 ,  A61M1/125 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/30 ,  F04D3/02 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042

Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject, the blood pump including an impeller that includes proximal and distal bushings, and a frame disposed around the impeller, the frame including proximal and distal bearings. An axial shaft passes through the proximal and distal bearings of the frame and the proximal and distal bushings of the impeller. The impeller defines a radially-constrained configuration in which the impeller is introduced into the subject's body and a non-radially-constrained configuration in which the impeller is configured to pump blood within the subject's body. The impeller changes from its radially-constrained configuration to its non-radially constrained configuration by the distal bushing sliding over the axial shaft.

公开(公告)号：US20190209751A1

公开(公告)日：2019-07-11

申请号：US16280566

申请日：2019-02-20

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10

CPC classification number: A61M1/122 ,  A61B5/0215 ,  A61B5/042 ,  A61M1/1008 ,  A61M1/1013 ,  A61M1/102 ,  A61M1/1031 ,  A61M1/1034 ,  A61M1/1036 ,  A61M1/1086 ,  A61M1/125 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/30 ,  F04D3/02 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042

Abstract: Apparatus and methods are described including a blood pump that includes an impeller that has proximal and distal bushings, and is configured to pump blood through a subject's body. A frame, which includes proximal and distal bearings, is disposed around the impeller. An axial shaft passes through the proximal and distal bearings of the frame and the proximal and distal bushings of the impeller. The axial shaft is coupled to at least one of the proximal and distal bushings of the impeller, such that the at least one bushing is held in an axially-fixed position with respect to the axial shaft, and is not held in an axially-fixed position with respect to the proximal and distal bearings. Other applications are also described.

公开(公告)号：US20250090833A1

公开(公告)日：2025-03-20

申请号：US18958181

申请日：2024-11-25

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M60/422 ,  A61B5/0215 ,  A61B5/283 ,  A61M60/13 ,  A61M60/135 ,  A61M60/148 ,  A61M60/174 ,  A61M60/237 ,  A61M60/40 ,  A61M60/414 ,  A61M60/419 ,  A61M60/50 ,  A61M60/531 ,  A61M60/538 ,  A61M60/554 ,  A61M60/806 ,  A61M60/818 ,  A61M60/824 ,  A61M60/825 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject. The blood pump includes an impeller that defines a lumen therethrough, and an axial shaft that passes through the lumen. The impeller is configured to assume a radially-constrained configuration by becoming axially elongated. Other applications are also described.

公开(公告)号：US20250000376A1

公开(公告)日：2025-01-02

申请号：US18882984

申请日：2024-09-12

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

Abstract: Apparatus and methods are described including a left ventricular assist device that includes an axial flow impeller configured to be disposed within a subject's left ventricle and to pump blood axially from the subject's left ventricle to the subject's aorta. A frame is disposed around the impeller, the frame being shaped such that, in a non-radially-constrained configuration of the frame, the frame defines a central cylindrical portion, and a distal conical portion. The frame is at least partially covered with one or more tube portions, the tube portions defining one or more blood-inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube portions, wherein at least some of the one or more blood-inlet openings are at least partially disposed over the distal conical portion of the frame. Other applications are also described.

公开(公告)号：US20210038791A1

公开(公告)日：2021-02-11

申请号：US17069321

申请日：2020-10-13

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus and methods are described including a blood pump that is placed inside a body of subject. The blood pump includes an impeller that includes proximal and distal bushings, and that defines an axial lumen that extends from the proximal bushing to the distal bushing, a frame disposed around the impeller, and an axial shaft that passes through the proximal and distal bushings of the impeller. A distal end of a delivery catheter, and the frame and the impeller, are configured to be moved with respect to one another, to thereby cause the frame to assume a radially-constrained configuration by the frame becoming axially elongated, and cause the impeller to assume a radially-constrained configuration by the impeller becoming axially elongated. Other applications are also described.

公开(公告)号：US20190209757A1

公开(公告)日：2019-07-11

申请号：US16279352

申请日：2019-02-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/12 ,  A61M1/10

CPC classification number: A61M1/122 ,  A61B5/0215 ,  A61B5/042 ,  A61M1/1008 ,  A61M1/1013 ,  A61M1/102 ,  A61M1/1031 ,  A61M1/1034 ,  A61M1/1036 ,  A61M1/1086 ,  A61M1/125 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/30 ,  F04D3/02 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042

Abstract: Apparatus and methods are described including placing, into a subject's body, a blood-pump tube, with a blood pump disposed within the blood-pump tube. At least one blood-pressure-measurement tube, which defines an opening at a distal end thereof, extends to at least an outer surface of the blood-pump tube, such that the opening at the distal end of the blood-pressure-measurement tube is in direct fluid communication with a bloodstream of the subject outside the blood-pump tube. Blood is pumped through the blood-pump tube, using the blood pump. Pressure of the bloodstream of the subject outside the blood-pump tube is measured by measuring pressure of blood within the blood-pressure-measurement tube. Other applications are also described.

公开(公告)号：US20210023286A1

公开(公告)日：2021-01-28

申请号：US17069570

申请日：2020-10-13

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/10 ,  A61B5/0215 ,  A61M1/12 ,  F04D3/02 ,  F04D15/00 ,  F04D29/041 ,  F04D29/042 ,  F04D25/02 ,  A61B5/042 ,  F04D29/18 ,  F04D29/24 ,  F04D7/00

Abstract: Apparatus and methods are described including a blood pump catheter that includes an axial shaft, and an impeller disposed on the axial shaft. A motor drives the impeller to pump blood, by rotating the impeller. A drive cable extends from the motor to the axial shaft, the drive cable being configured to impart rotational motion from the motor to the impeller by rotating. A distal tip portion is disposed at a distal end of the blood pump catheter. The drive cable, the axial shaft, and the distal tip portion define a continuous lumen therethrough from outside the subject's body to the distal end of the blood pump catheter. The continuous lumen facilitates insertion of the blood pump catheter into the subject's body over a guidewire, and, subsequently, provides a channel through which the purging fluid flows. Other applications are also described.

公开(公告)号：US20190209756A1

公开(公告)日：2019-07-11

申请号：US16278482

申请日：2019-02-18

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61M1/12 ,  A61M1/10

CPC classification number: A61M1/122 ,  A61B5/0215 ,  A61B5/042 ,  A61M1/1008 ,  A61M1/1013 ,  A61M1/102 ,  A61M1/1031 ,  A61M1/1034 ,  A61M1/1036 ,  A61M1/1086 ,  A61M1/125 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/30 ,  F04D3/02 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042

Abstract: Apparatus and methods are described including placing a blood pump into a subject's body, the blood pump including an axial shaft, an impeller disposed on the axial shaft, and a drive cable extending from outside the subject's body to the axial shaft. The impeller is driven to pump blood from a distal end of the impeller to a proximal end of the impeller by imparting rotational motion to the impeller via the drive cable, in a given direction of rotation. At least a portion of the drive cable includes a plurality of wires disposed in a coiled configuration that is such that, in response to the drive cable rotating in the given direction of rotation, the plurality of wires disposed in the coiled configuration at least partially unwind, such that the portion of the drive cable shortens axially. Other applications are also described.