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公开(公告)号:US10603362B2
公开(公告)日:2020-03-31
申请号:US15640977
申请日:2017-07-03
发明人: Aiko Ohmachi , Hiroaki Matsuyama , Yoshikazu Morita , Yuko Ishida , Takayuki Nara , Ken Kato , Atsushi Serizawa , Hiroshi Ueno , Hiroshi Urazono
摘要: The invention relates to a drink includes angiogenin and/or angiogenin hydrolysate in an amount of more than 0.8 mg/100 ml and not more than 150 mg/100 ml, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.3 to 23.
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公开(公告)号:US20150086698A1
公开(公告)日:2015-03-26
申请号:US14552012
申请日:2014-11-24
发明人: Susumu Miura , Kenji Kojima , Taku Nakano , Ken Kato , Akira Tomizawa , Toshimitsu Yoshioka
CPC分类号: A23C9/1422 , A23C19/0455 , A23C21/00 , A23C2210/20 , A23C2240/05 , A23L33/115 , A23L33/40 , A61K35/20
摘要: Manufacture a powder with high milk-derived complex lipid content that contains milk-derived phospholipids and milk-derived ganglioside at high concentrations, which contains protein by 15 to 35 percent by dry weight and fat by 45 to 60 percent by dry weight, wherein the content of milk-derived complex lipids is 20 percent by dry weight or more, and which can be utilized as a material for functional food, mother's milk substitute or drug, by means of adjusting the pH value of a butter serum or butter serum powder reconstituted liquid to a range of 4.0 to 5.0, adding calcium chloride to promote coagulation of protein, removing the produced sediments, filtering the supernatant by means of ultrafiltration or microfiltration, and then drying the obtained concentrate.
摘要翻译: 以高浓度制造含有乳源性磷脂和乳源神经节苷脂的高乳衍生复合脂质含量的粉末,其含有15〜35%的干重和45〜60%的干重的蛋白质,其中, 乳源性复合脂质的含量为干重的20%以上,可以通过调整黄油血清或黄油血清粉末的pH值而重新配制,可用作功能性食品,母乳替代物或药物的材料。 液体至4.0〜5.0的范围,加入氯化钙促进蛋白质凝结,除去生成的沉淀物,通过超滤或微滤过滤上清液,然后干燥得到的浓缩物。
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公开(公告)号:US10376543B2
公开(公告)日:2019-08-13
申请号:US15450596
申请日:2017-03-06
发明人: Aiko Ohmachi , Hiroaki Matsuyama , Yoshikazu Morita , Yuko Ishida , Takayuki Nara , Ken Kato , Atsushi Serizawa , Hiroshi Ueno , Hiroshi Urazono
摘要: The invention relates to provide a fermented milk product includes angiogenin and/or angiogenin hydrolysate in an amount of 0.9 mg/100 g to 150 mg/100 g, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.3 to 23.
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公开(公告)号:US20150132276A1
公开(公告)日:2015-05-14
申请号:US14397707
申请日:2013-04-30
发明人: Yoshihiko Takano , Takayuki Nara , Ken Kato , Yoshikazu Morita
CPC分类号: A61K35/20 , A23K20/142 , A23K20/147 , A23K50/40 , A23L2/66 , A23L33/10 , A23L33/18 , A23L33/19 , A23V2002/00 , A61K38/018 , A61K38/30 , A61K38/40 , A61K38/44 , A61K38/482 , C12Y111/01007 , A23V2200/326 , A23V2250/54 , A23V2250/542 , A23V2250/5424
摘要: It is an object of the present invention to provide a chondrogenesis promoter that is safe and exhibits a chondrogenesis-promoting effect by daily ingestion. It is also an object of the invention to provide a proteoglycan synthesis promoter that exhibits a proteoglycan synthesis-promoting effect by ingestion. Provided are a chondrogenesis promoter and a proteoglycan synthesis promoter each containing a milk-derived basic protein fraction as an active ingredient. Synthesis of proteoglycan and formation of a cartilage can be promoted by oral ingestion of the milk-derived basic protein fraction. A hydrolysate of the milk-derived basic protein fraction also has a similar chondrogenesis-promoting effect.
摘要翻译: 本发明的目的是提供一种安全的软骨形成促进剂,其通过日摄取显示软骨形成促进作用。 本发明的另一个目的是提供通过摄取显示蛋白多糖合成促进作用的蛋白聚糖合成促进剂。 提供了各自含有来自乳的碱性蛋白质级分作为活性成分的软骨形成促进剂和蛋白多糖合成促进剂。 可以通过口服摄取乳源性碱性蛋白质级分来促进蛋白聚糖的合成和软骨的形成。 乳衍生的碱性蛋白质级分的水解产物也具有类似的软骨形成促进作用。
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公开(公告)号:US09861687B2
公开(公告)日:2018-01-09
申请号:US15684175
申请日:2017-08-23
发明人: Aiko Ohmachi , Hiroaki Matsuyama , Yoshikazu Morita , Yuko Ishida , Takayuki Nara , Ken Kato , Atsushi Serizawa
IPC分类号: A61K38/54 , A61K38/46 , A23L33/18 , A23L33/17 , A23K50/40 , A23K20/189 , A23K20/142 , A23K20/147 , A23L2/66 , A61K38/44 , A61K38/18
CPC分类号: A61K38/54 , A23K20/142 , A23K20/147 , A23K20/189 , A23K50/40 , A23L2/66 , A23L33/17 , A23L33/18 , A23V2002/00 , A23V2200/00 , A61K38/1891 , A61K38/44 , A61K38/465 , C12Y111/01007 , C12Y301/27 , A61K2300/00 , A23V2200/306
摘要: The invention relates to a protein material includes angiogenin and/or angiogenin hydrolysate in an amount of 2 to 15 mg/100 mg, and lactoperoxidase and/or lactoperoxidase hydrolysate, in the mass ratio to angiogenin and/or angiogenin hydrolysate of 0.3 to 20.
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公开(公告)号:US09186366B2
公开(公告)日:2015-11-17
申请号:US13862718
申请日:2013-04-15
发明人: Ken Kato , Susumu Miura , Leo Tanaka , Hiroshi Ueno , Noriko Ueda , Yuko Haruta , Toshimitsu Yoshioka
IPC分类号: A61K31/688 , A23K1/16 , A23K1/18 , A23L1/30 , A23L2/52 , A61K8/68 , A61Q7/00 , A61Q19/02 , C07F9/10
CPC分类号: A61K31/688 , A23K20/158 , A23K50/40 , A23K50/48 , A23L2/52 , A23L33/10 , A23L33/12 , A23V2002/00 , A61K8/68 , A61Q7/00 , A61Q19/02 , C07F9/10 , A23V2250/21 , A23V2200/304 , A23V2200/32
摘要: It is intended to find novel pharmaceutical use of sphingomyelin and to provide preventive or therapeutic agents for various diseases as well as a food and drink product and feed comprising any of these agents. The present invention provides a pharmaceutical agent which contains sphingomyelin as an active ingredient and is any of the following agents: 1) a sialomucin secretion promoter, 2) an agent for preventing drunken sickness (hangover), 3) an antiallergic agent, 4) an antioxidant, 5) an agent for defending against infection, 6) a hair growth agent, 7) a therapeutic agent for demyelinating disease, 8) an anti-pigmentation agent, 9) an anti-inflammatory agent, and 10) an agent for improving learning ability. The present invention also provides a food and drink product or feed, characterized by comprising the agent. It is preferred that the sphingomyelin should be derived from milk.
摘要翻译: 旨在找到鞘磷脂的新药用途,并提供各种疾病的预防或治疗剂,以及包含任何这些药剂的食品和饮料产品和饲料。 本发明提供含有鞘磷脂作为活性成分的药剂,其为以下药剂:1)唾液酸粘蛋白分泌促进剂,2)防酒醉药(宿醉)3,抗过敏剂4) 抗氧化剂,5)防止感染的药剂,6)毛发生长剂,7)脱髓鞘疾病的治疗剂,8)抗色素沉着剂,9)抗炎剂,和10)改善剂 学习能力 本发明还提供一种食品和饮料产品或饲料,其特征在于包含该试剂。 鞘磷脂优选来源于牛奶。
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公开(公告)号:US08486916B2
公开(公告)日:2013-07-16
申请号:US13676430
申请日:2012-11-14
发明人: Ken Kato , Susumu Miura , Leo Tanaka , Hiroshi Ueno , Noriko Ueda , Yuko Haruta , Toshimitsu Yoshioka
IPC分类号: A61K31/685 , A23J7/00
CPC分类号: A61K31/688 , A23K20/158 , A23K50/40 , A23K50/48 , A23L2/52 , A23L33/10 , A23L33/12 , A23V2002/00 , A61K8/68 , A61Q7/00 , A61Q19/02 , C07F9/10 , A23V2250/21 , A23V2200/304 , A23V2200/32
摘要: It is intended to find novel pharmaceutical use of sphingomyelin and to provide preventive or therapeutic agents for various diseases as well as a food and drink product and feed comprising any of these agents. The present invention provides a pharmaceutical agent which contains sphingomyelin as an active ingredient and is any of the following agents: 1) a sialomucin secretion promoter, 2) an agent for preventing drunken sickness (hangover), 3) an antiallergic agent, 4) an antioxidant, 5) an agent for defending against infection, 6) a hair growth agent, 7) a therapeutic agent for demyelinating disease, 8) an anti-pigmentation agent, 9) an anti-inflammatory agent, and 10) an agent for improving learning ability. The present invention also provides a food and drink product or feed, characterized by comprising the agent. It is preferred that the sphingomyelin should be derived from milk.
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