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公开(公告)号：US11578158B2
公开(公告)日：2023-02-14
申请号：US16960098
申请日：2018-01-31
申请人： MENICON CO., LTD.
发明人： Yuya Suganuma , Hiroko Nomura , Tatsuya Ojio , Keishi Tsukamoto
IPC分类号： C08F220/12 , C08F220/30 , A61L27/16 , C08F220/28 , C08F220/16 , C08F220/18
摘要： The present invention provides a material for intraocular lens which has improved hydrolysis resistance. The material for intraocular lens according to the present invention is obtained by polymerizing a monomer composition comprising: a base monomer, a hydrophilic monomer, and a cross-likable monomer, wherein the base monomer comprises an aromatic ring-containing acrylate monomer and an alkoxyalkyl methacrylate monomer having an alkoxyalkyl group having four or less carbon atoms. A blending ratio on a molar basis of the methacrylate monomer with respect to the acrylate monomer in all the monomer components contained in the monomer composition is 0.25 to 1.00.
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公开(公告)号：US10716875B2
公开(公告)日：2020-07-21
申请号：US16084717
申请日：2018-01-31
申请人： MENICON CO., LTD.
发明人： Yuya Suganuma , Hiroko Nomura , Tatsuya Ojio , Keishi Tsukamoto
IPC分类号： A61L27/16 , C08F220/18 , C08F220/28 , C08F220/30
摘要： An intraocular lens includes a polymeric lens material formed from a polymerizable composition. The polymerizable composition includes: (a) a single aromatic acrylate monomer which is an aromatic-ring containing acrylate; (b) an alkoxyalkyl methacrylate monomer having an alkoxyalkyl group with 4 or less carbon atoms; (c) an alkyl acrylate monomer having an alkyl group with 1 to 20 carbon atoms; (d) a hydrophilic monomer; and (e) a crosslinkable monomer.
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公开(公告)号：US10117965B1
公开(公告)日：2018-11-06
申请号：US15772273
申请日：2017-07-27
申请人： MENICON CO., LTD
发明人： Yuya Suganuma , Hiroko Nomura , Tatsuya Ojio
IPC分类号： A61L27/16 , A61L27/50 , C08F222/14 , C08F220/30 , C08F220/28
CPC分类号： A61L27/16 , A61L27/50 , A61L2430/16 , C08F220/30 , C08F222/14 , C08F2220/286 , C08F2220/301
摘要： An intraocular lens material disclosed in the present description includes an aromatic ring-containing acrylate structural unit, an alkoxyalkyl methacrylate structural unit including an alkoxy group having 4 or less carbon atoms, a hydrophilic structural unit based on a hydrophilic monomer, and a cross-linking structural unit based on a cross-linkable monomer.
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公开(公告)号：US10702606B2
公开(公告)日：2020-07-07
申请号：US15780686
申请日：2015-12-10
申请人： MENICON CO., LTD.
发明人： Yuya Suganuma , Tatsuya Ojio , Hidenori Yokoi
摘要： The present invention provides a peptide composition that can achieve both excellent storage stability and transparency. The peptide composition of the present invention includes: a self-assembling peptide; a buffering agent having a pKa of 3.5 or more and less than 7.5 and containing one or more nitrogen atoms; and water, and has a pH of from 4.5 to 6.6.
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公开(公告)号：US10632204B2
公开(公告)日：2020-04-28
申请号：US15780686
申请日：2015-12-10
申请人： MENICON CO., LTD.
发明人： Yuya Suganuma , Tatsuya Ojio , Hidenori Yokoi
摘要： The present invention provides a peptide composition that can achieve both excellent storage stability and transparency. The peptide composition of the present invention includes: a self-assembling peptide; a buffering agent having a pKa of 3.5 or more and less than 7.5 and containing one or more nitrogen atoms; and water, and has a pH of from 4.5 to 6.6.
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