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公开(公告)号：US06998073B2
公开(公告)日：2006-02-14
申请号：US10321951
申请日：2002-12-17
IPC分类号： B29D11/00
CPC分类号： B29C71/0009 , B29C37/0003 , B29C71/009 , B29C2071/0027 , B29C2071/0054 , B29D11/00067 , B29D11/00125 , B29D11/023 , B29L2011/0016 , B29L2011/0041 , Y10S134/901
摘要： A method of extracting residual materials from a polymeric, ophthalmic biomedical device, such as a contact lens, by using a mixture comprised of a primary solvent, such as carbon dioxide, and a polar co-solvent, such as isopropanol. By exposing the device to the co-solvent, the device expands. By pulsing or varying the concentration of the polar co-solvent in the mixture, the lens dimensions vary accordingly. When the lens is extracted while retained in a mold, the changes in lens dimensions causes the lens to be released from the mold.
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公开(公告)号：US06514438B1
公开(公告)日：2003-02-04
申请号：US09698418
申请日：2000-10-27
IPC分类号： B29D1100
CPC分类号： B29C71/0009 , B29C37/0003 , B29C71/009 , B29C2071/0027 , B29C2071/0054 , B29D11/00067 , B29D11/00125 , B29D11/023 , B29L2011/0016 , B29L2011/0041 , Y10S134/901
摘要： A method of extracting residual materials from a polymeric, ophthalmic biomedical device, such as a contact lens, by using a mixture comprised of a primary solvent, such as carbon dioxide, and a polar co-solvent, such as isopropanol. By exposing the device to the co-solvent, the device expands. By pulsing or varying the concentration of the polar co-solvent in the mixture, the lens dimensions vary accordingly. When the lens is extracted while retained in a mold, the changes in lens dimensions causes the lens to be released from the mold.
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公开(公告)号：US07022813B2
公开(公告)日：2006-04-04
申请号：US10145286
申请日：2002-05-13
申请人： Madhu Ayyagari , Erik M. Indra , Mahendra P. Nandu
发明人： Madhu Ayyagari , Erik M. Indra , Mahendra P. Nandu
IPC分类号： C08J3/00
CPC分类号： C11D3/046 , A61L12/141 , B01D15/00 , B01J20/08 , B01J20/103 , B01J20/20 , C08J7/02 , C08J11/02 , C11D1/44 , C11D3/0078 , C11D3/221 , C11D3/222 , C11D3/48 , G02B1/043
摘要： A process for treating biomedical devices, especially contact lenses, involves contacting polymeric devices containing extractables with a solvent that dissolves and thereby removes the extractables from the device, treating the solvent to remove extractables from the solvent, thereby purifying the solvent, and using the purified solvent to remove additional extractables from polymeric devices.
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4.发明授权公开(公告)号：US06423820B1
公开(公告)日：2002-07-23
申请号：US09667902
申请日：2000-09-22
申请人： Madhu Ayyagari , Erik M. Indra , Mahendra P. Nandu
发明人： Madhu Ayyagari , Erik M. Indra , Mahendra P. Nandu
IPC分类号： C08J300
CPC分类号： C11D3/046 , A61L12/141 , B01D15/00 , B01J20/08 , B01J20/103 , B01J20/20 , C08J7/02 , C08J11/02 , C11D1/44 , C11D3/0078 , C11D3/221 , C11D3/222 , C11D3/48 , G02B1/043
摘要： A process for treating biomedical devices, especially contact lenses, involves contacting polymeric devices containing extractables with a solvent that dissolves and thereby removes the extractables from the device, treating the solvent to remove extractables from the solvent, thereby purifying the solvent, and using the purified solvent to remove additional extractables from polymeric devices.
摘要翻译： 用于治疗生物医学装置，特别是隐形眼镜的方法包括将含有可萃取物的聚合物装置与溶解的溶剂接触，所述溶剂溶解并从而从装置中除去可提取物，处理溶剂以除去溶剂中的可萃取物，从而纯化溶剂，并使用纯化 溶剂以从聚合物装置中除去附加的可萃取物。
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5.发明授权公开(公告)号：US07276619B2
公开(公告)日：2007-10-02
申请号：US10801741
申请日：2004-03-16
IPC分类号： C07F7/02
CPC分类号： A61K31/80 , A61K31/695 , C07F7/089 , C07F7/20 , C08G77/34 , Y02P20/544
摘要： A process for the purification of a silicone oil or fluid using neat supercritical carbon dioxide or a supercritical carbon dioxide mixture extraction to produce vitreoretinal silicone tamponades. The subject process is an economical, highly effective, reproducible, contaminant-free method by which unreacted relatively low molecular weight cyclic siloxanes and oligomers are removed from relatively high molecular weight silicone oil or fluid.
摘要翻译： 使用纯超临界二氧化碳或超临界二氧化碳混合物萃取来纯化硅油或流体以产生玻璃体视丝素硅酮填塞物的方法。 本发明方法是经济的，高效的，可重复的，无污染的方法，通过该方法从相对高分子量的硅油或流体中除去未反应的相对低分子量的环状硅氧烷和低聚物。
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