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公开(公告)号:US06514438B1
公开(公告)日:2003-02-04
申请号:US09698418
申请日:2000-10-27
IPC分类号: B29D1100
CPC分类号: B29C71/0009 , B29C37/0003 , B29C71/009 , B29C2071/0027 , B29C2071/0054 , B29D11/00067 , B29D11/00125 , B29D11/023 , B29L2011/0016 , B29L2011/0041 , Y10S134/901
摘要: A method of extracting residual materials from a polymeric, ophthalmic biomedical device, such as a contact lens, by using a mixture comprised of a primary solvent, such as carbon dioxide, and a polar co-solvent, such as isopropanol. By exposing the device to the co-solvent, the device expands. By pulsing or varying the concentration of the polar co-solvent in the mixture, the lens dimensions vary accordingly. When the lens is extracted while retained in a mold, the changes in lens dimensions causes the lens to be released from the mold.
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2.
公开(公告)号:US06423820B1
公开(公告)日:2002-07-23
申请号:US09667902
申请日:2000-09-22
申请人: Madhu Ayyagari , Erik M. Indra , Mahendra P. Nandu
发明人: Madhu Ayyagari , Erik M. Indra , Mahendra P. Nandu
IPC分类号: C08J300
CPC分类号: C11D3/046 , A61L12/141 , B01D15/00 , B01J20/08 , B01J20/103 , B01J20/20 , C08J7/02 , C08J11/02 , C11D1/44 , C11D3/0078 , C11D3/221 , C11D3/222 , C11D3/48 , G02B1/043
摘要: A process for treating biomedical devices, especially contact lenses, involves contacting polymeric devices containing extractables with a solvent that dissolves and thereby removes the extractables from the device, treating the solvent to remove extractables from the solvent, thereby purifying the solvent, and using the purified solvent to remove additional extractables from polymeric devices.
摘要翻译: 用于治疗生物医学装置,特别是隐形眼镜的方法包括将含有可萃取物的聚合物装置与溶解的溶剂接触,所述溶剂溶解并从而从装置中除去可提取物,处理溶剂以除去溶剂中的可萃取物,从而纯化溶剂,并使用纯化 溶剂以从聚合物装置中除去附加的可萃取物。
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公开(公告)号:US06998073B2
公开(公告)日:2006-02-14
申请号:US10321951
申请日:2002-12-17
IPC分类号: B29D11/00
CPC分类号: B29C71/0009 , B29C37/0003 , B29C71/009 , B29C2071/0027 , B29C2071/0054 , B29D11/00067 , B29D11/00125 , B29D11/023 , B29L2011/0016 , B29L2011/0041 , Y10S134/901
摘要: A method of extracting residual materials from a polymeric, ophthalmic biomedical device, such as a contact lens, by using a mixture comprised of a primary solvent, such as carbon dioxide, and a polar co-solvent, such as isopropanol. By exposing the device to the co-solvent, the device expands. By pulsing or varying the concentration of the polar co-solvent in the mixture, the lens dimensions vary accordingly. When the lens is extracted while retained in a mold, the changes in lens dimensions causes the lens to be released from the mold.
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公开(公告)号:US07022813B2
公开(公告)日:2006-04-04
申请号:US10145286
申请日:2002-05-13
申请人: Madhu Ayyagari , Erik M. Indra , Mahendra P. Nandu
发明人: Madhu Ayyagari , Erik M. Indra , Mahendra P. Nandu
IPC分类号: C08J3/00
CPC分类号: C11D3/046 , A61L12/141 , B01D15/00 , B01J20/08 , B01J20/103 , B01J20/20 , C08J7/02 , C08J11/02 , C11D1/44 , C11D3/0078 , C11D3/221 , C11D3/222 , C11D3/48 , G02B1/043
摘要: A process for treating biomedical devices, especially contact lenses, involves contacting polymeric devices containing extractables with a solvent that dissolves and thereby removes the extractables from the device, treating the solvent to remove extractables from the solvent, thereby purifying the solvent, and using the purified solvent to remove additional extractables from polymeric devices.
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公开(公告)号:US06634931B2
公开(公告)日:2003-10-21
申请号:US09734439
申请日:2000-12-11
申请人: Madhu Ayyagari , Mahendra P. Nandu
发明人: Madhu Ayyagari , Mahendra P. Nandu
IPC分类号: B24B100
CPC分类号: B24B13/0006 , B24B31/003
摘要: A process of dry polishing molded or lathe cut intraocular lenses to removing flash, sharp edges and/or surface irregularities therefrom. The process includes rotational tumbling of partially protected intraocular lenses in a dry polishing media. The process is suitable for single piece and multipiece intraocular lenses of varying composition.
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公开(公告)号:US06575814B1
公开(公告)日:2003-06-10
申请号:US09642349
申请日:2000-08-21
申请人: Madhu Ayyagari , Mahendra P. Nandu
发明人: Madhu Ayyagari , Mahendra P. Nandu
IPC分类号: B25B100
CPC分类号: B24B13/0006 , B24B31/10
摘要: A process of dry polishing molded or lathe cut intraocular lenses or like medical devices to removing flash, sharp edges and/or surface irregularities therefrom. The process includes gas and/or rotational tumbling of the intraocular lenses or like medical devices in a dry polishing media. The process is suitable for single piece and multipiece intraocular lenses of varying composition.
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公开(公告)号:US06612907B2
公开(公告)日:2003-09-02
申请号:US10217245
申请日:2002-08-09
申请人: Madhu Ayyagari , Mahendra P. Nandu
发明人: Madhu Ayyagari , Mahendra P. Nandu
IPC分类号: B24B500
CPC分类号: B24B13/0006 , B24B31/10
摘要: A process of dry polishing molded or lathe cut intraocular lenses or like medical devices to removing flash, sharp edges and/or surface irregularities therefrom. The process includes gas and/or rotational tumbling of the intraocular lenses or like medical devices in a dry polishing media. The process is suitable for single piece and multipiece intraocular lenses of varying composition.
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公开(公告)号:US20050285288A1
公开(公告)日:2005-12-29
申请号:US11210392
申请日:2005-08-24
申请人: Madhu Ayyagari , Mahendra Nandu , Erik Indra , Alan Braun
发明人: Madhu Ayyagari , Mahendra Nandu , Erik Indra , Alan Braun
CPC分类号: B29C71/0009 , B29C37/0003 , B29C71/009 , B29C2071/0027 , B29C2071/0054 , B29D11/00067 , B29D11/00125 , B29D11/023 , B29L2011/0016 , B29L2011/0041 , Y10S134/901
摘要: A method of extracting residual materials from a polymeric, ophthalmic biomedical device, such as a contact lens, by using a mixture comprised of a primary solvent, such as carbon dioxide, and a polar co-solvent, such as isopropanol: By exposing the device to the co-solvent, the device expands. By pulsing or varying the concentration of the polar co-solvent in the mixture, the lens dimensions vary accordingly. When the lens is extracted while retained in a mold, the changes in lens dimensions causes the lens to be released from the mold.
摘要翻译: 通过使用由主要溶剂如二氧化碳和极性助溶剂如异丙醇组成的混合物从聚合物眼科生物医学装置(例如隐形眼镜)中提取残留物质的方法:通过使装置曝光 对共溶剂,器件扩大。 通过脉冲或改变混合物中极性助溶剂的浓度,透镜尺寸相应地变化。 当保持在模具中时提取透镜时,透镜尺寸的变化导致透镜从模具中释放出来。
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公开(公告)号:US06362314B1
公开(公告)日:2002-03-26
申请号:US09244005
申请日:1999-02-04
IPC分类号: C08G6538
摘要: A process of controlling the molecular weight and dispersity of poly(p-ethylphenol) and poly(m-cresol) synthesized enzymatically by varying the composition of the reaction medium. Polymers with low dispersities and molecular weights from 1000 to 3000 are synthesized in reversed micelles and biphasic systems. In comparison, reactions in bulk solvents resulted in a narrow range of molecular weights (281 to 675 with poly(p-ethylphenol) in a DMF/water system and 1,400 to 25,000 with poly(m-cresol) in an ethanol/water system). Poly(p-ethylphenol) was functionalized at hydroxyl positions with palmitoyl, cinnamoyl, and biotin groups.
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公开(公告)号:US6096859A
公开(公告)日:2000-08-01
申请号:US598737
申请日:1996-01-16
CPC分类号: C08G61/10
摘要: A process of controlling the molecular weight and dispersity of poly(p-ethylphenol) and poly(m-cresol) synthesized enzymatically by varying the composition of the reaction medium. Polymers with low dispersities and molecular weights from 1000 to 3000 are synthesized in reversed micelles and biphasic systems. In comparison, reactions in bulk solvents resulted in a narrow range of molecular weights (281 to 675 with poly(p-ethylphenol) in a DMF/water system and 1,400 to 25,000 with poly(m-cresol) in an ethanol/water system). Poly(p-ethylphenol) was functionalized at hydroxyl positions with palmitoyl, cinnamoyl, and biotin groups.
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