公开(公告)号：US12127820B2

公开(公告)日：2024-10-29

申请号：US16952327

申请日：2020-11-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

CPC classification number: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/181 ,  F04D29/247 ,  A61M2205/0266 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/30

Abstract: Apparatus and methods are described including a left ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject and to pump blood from the left ventricle to an aorta of the subject, by rotating. A frame is disposed around the impeller. A tube is configured to traverse an aortic valve of the subject, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube extends to a distal end of the frame and defines one or more lateral blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. Other applications are also described.

公开(公告)号：US20240341943A1

公开(公告)日：2024-10-17

申请号：US18388383

申请日：2023-11-09

Applicant: Magenta Medical Ltd

Inventor： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman

IPC: A61F2/07 ,  A61B5/0205 ,  A61M60/13 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/33 ,  A61M60/411 ,  A61M60/414 ,  A61M60/422 ,  A61M60/523 ,  A61M60/808 ,  A61M60/81 ,  A61M60/825 ,  A61M60/833 ,  A61M60/861 ,  A61M60/896

CPC classification number: A61F2/07 ,  A61B5/02055 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/33 ,  A61M60/411 ,  A61M60/422 ,  A61M60/523 ,  A61M60/808 ,  A61M60/81 ,  A61M60/825 ,  A61M60/833 ,  A61M60/861 ,  A61M60/148 ,  A61M60/414 ,  A61M60/896 ,  A61M2207/00 ,  A61M2210/1082 ,  A61M2210/12

Abstract: Apparatus and methods are described including an impeller for use in a blood pump. An impeller frame includes proximal and distal end portions and at least one helical elongate element that winds from the proximal end portion to the distal end portion. A material is coupled to the helical elongate element, such that the helical elongate element with the material coupled thereto defines a blade of the impeller. A mediator is coupled to the helical elongate element. The helical elongate element has a first stiffness, the material has a lower stiffness than the first stiffness, and the mediator is configured to enhance bonding between the helical elongate element and the material. Other applications are also described.

公开(公告)号：US20240090780A1

公开(公告)日：2024-03-21

申请号：US18511532

申请日：2023-11-16

Applicant: Magenta Medical Ltd

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

CPC classification number: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/181 ,  F04D29/247 ,  A61M2205/0266 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/30

Abstract: Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject, and a frame configured to be disposed around the impeller. The frame is shaped such that, in a non-radially constrained configuration of the frame, the frame defines a cylindrical central portion, and a distal conical portion that is disposed distally with respect to the cylindrical central portion and that widens from a distal end of the frame to a distal end of the cylindrical central portion. The frame defines struts that define openings therebetween, and all openings that are defined at least partially within the distal conical portion of the frame extend into the cylindrical central portion of the frame. Other applications are also described.

公开(公告)号：US11703064B2

公开(公告)日：2023-07-18

申请号：US17672077

申请日：2022-02-15

Applicant: ECP ENTWICKLUNGSGESELLSCHAFT MBH

Inventor： Lars Bredenbreuker ,  Joerg Schumacher

IPC: F04D29/18 ,  F04D15/00 ,  F04D29/02 ,  F04D29/24 ,  F04D29/52 ,  A61M60/896 ,  A61M60/13 ,  A61M60/237 ,  A61M60/81 ,  A61M60/205 ,  A61M60/148 ,  A61M60/414 ,  A61M60/135

CPC classification number: F04D29/18 ,  A61M60/13 ,  A61M60/205 ,  A61M60/237 ,  A61M60/81 ,  A61M60/896 ,  F04D15/0005 ,  F04D29/026 ,  F04D29/181 ,  F04D29/247 ,  F04D29/528 ,  A61M60/135 ,  A61M60/148 ,  A61M60/414 ,  A61M2205/04 ,  A61M2210/125 ,  F05D2300/174 ,  F05D2300/505 ,  F05D2300/603 ,  F05D2300/6034

Abstract: In a pump housing having an interior for accommodating a pump rotor, which may be transferred from a radially compressed state into a radially expanded state, and comprises a housing skin revolving in circumferential direction, as well as at least one reinforcement element, a stretch-resistant element revolving in circumferential direction is provided, which is stretched less than 5% in the expanded state as opposed to the force-free state in circumferential direction, and which limits any further expansion of the pump housing in radial direction.

公开(公告)号：US20240358980A1

公开(公告)日：2024-10-31

申请号：US18660326

申请日：2024-05-10

Applicant: Abiomed Europe GmbH

Inventor： Thorsten Siess ,  Christoph Nix ,  Walid Aboulhosn

IPC: A61M25/10 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/833 ,  A61M60/861 ,  A61M60/896

CPC classification number: A61M25/1002 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/833 ,  A61M60/861 ,  A61M60/896 ,  A61M2025/1052 ,  A61M2025/1061 ,  A61M2025/1084 ,  A61M2205/0266

Abstract: An intravascular blood pump (1) comprises a ring seal (10) that is configured to assume a collapsed configuration and an expanded configuration and configured to contact and seal against an inner wall of the patient's blood vessel when inserted therein in the expanded configuration. A support member (12; 13) is disposed inside the ring seal (10) in order to support the ring seal (10) from the inside, wherein the support member (12; 13) is configured to collapse at least partially when a predetermined pressure difference between a proximal area and a distal area of the blood vessel acting on the ring seal (10) is exceeded.

公开(公告)号：US12023481B2

公开(公告)日：2024-07-02

申请号：US18182738

申请日：2023-03-13

Applicant: Constantinos Anagnostopoulos

Inventor： Constantinos Anagnostopoulos

IPC: A61M60/497 ,  A61M60/13 ,  A61M60/139 ,  A61M60/295 ,  A61M60/843 ,  A61M60/865 ,  A61M60/896 ,  A61M60/148 ,  A61M60/274

CPC classification number: A61M60/896 ,  A61M60/13 ,  A61M60/139 ,  A61M60/295 ,  A61M60/497 ,  A61M60/843 ,  A61M60/865 ,  A61M60/148 ,  A61M60/274

Abstract: A circulatory assist apparatus comprises an inflatable pumping balloon having a proximal end joined to an elongated balloon catheter, the catheter having a distal end joined to the pumping balloon and a proximal end, separated from the distal end by a length sufficient to extend from within the circulatory lumen to the outside of a patient's body, for receiving positive and negative pressure pulses from a pump to inflate and deflate the pumping balloon; a proximal expandable frame comprising a distal portion of an elongated shaft surrounding the catheter; and a distal expandable frame. The distal end of the elongated shaft is abuttable against a stopping element surrounding the catheter as the shaft is advanced towards the inflatable pumping balloon, or is joined to the catheter in which case the proximal expandable frame is heat set to deploy spontaneously to a predetermined diameter upon release of the elongated shaft.

公开(公告)号：US12005208B2

公开(公告)日：2024-06-11

申请号：US17979015

申请日：2022-11-02

Applicant: Abiomed Europe GMBH

Inventor： Thorsten Siess ,  Christoph Nix ,  Walid Aboulhosn

IPC: A61M25/10 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/833 ,  A61M60/861 ,  A61M60/896

CPC classification number: A61M25/1002 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/833 ,  A61M60/861 ,  A61M60/896 ,  A61M2025/1052 ,  A61M2025/1061 ,  A61M2025/1084 ,  A61M2205/0266

Abstract: An intravascular blood pump (1) comprises a ring seal (10) that is configured to assume a collapsed configuration and an expanded configuration and configured to contact and seal against an inner wall of the patient's blood vessel when inserted therein in the expanded configuration. A support member (12; 13) is disposed inside the ring seal (10) in order to support the ring seal (10) from the inside, wherein the support member (12; 13) is configured to collapse at least partially when a predetermined pressure difference between a proximal area and a distal area of the blood vessel acting on the ring seal (10) is exceeded.

公开(公告)号：US11964143B2

公开(公告)日：2024-04-23

申请号：US17078439

申请日：2020-10-23

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M1/00 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/148 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804

CPC classification number: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

Abstract: Apparatus and methods are described, including a left-ventricular assist device that includes an impeller, and a frame disposed around the impeller, the frame having a length of more than 25 mm when disposed in a non-radially constrained configuration. A rigid axial shaft extends from a proximal end of the frame to a distal end of the frame. A motor is disposed outside a body of a subject, and drives the impeller to pump blood within the subject's body, by rotating. A drive cable extends from outside the subject's body to the axial shaft. The drive cable imparts rotational motion from the motor to the impeller by rotating. The drive cable is a flexible cable comprising a plurality of coiled wires. Other applications are also described.

公开(公告)号：US11950889B2

公开(公告)日：2024-04-09

申请号：US16952444

申请日：2020-11-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

CPC classification number: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/181 ,  F04D29/247 ,  A61M2205/0266 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/30

Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A braided element is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.

公开(公告)号：US20240225814A1

公开(公告)日：2024-07-11

申请号：US18510983

申请日：2023-11-16

Applicant: Magenta Medical Ltd

Inventor： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman

IPC: A61F2/07 ,  A61B5/0205 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/33 ,  A61M60/411 ,  A61M60/422 ,  A61M60/523 ,  A61M60/808 ,  A61M60/81 ,  A61M60/825 ,  A61M60/833 ,  A61M60/861 ,  A61M60/148 ,  A61M60/414 ,  A61M60/896

CPC classification number: A61F2/07 ,  A61B5/02055 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/33 ,  A61M60/411 ,  A61M60/422 ,  A61M60/523 ,  A61M60/808 ,  A61M60/81 ,  A61M60/825 ,  A61M60/833 ,  A61M60/861 ,  A61M60/148 ,  A61M60/414 ,  A61M60/896 ,  A61M2207/00 ,  A61M2210/1082 ,  A61M2210/12

Abstract: Apparatus and methods are described including an impeller configured, in a radially-expanded configuration thereof, to pump a fluid by rotating. A radially expandable cage is disposed around the impeller, such that, in radially-expanded configurations of the impeller and the cage, the impeller is separated from an inner surface of the cage. The impeller is disposed within the cage such that, in response to the cage becoming radially contracted and axially elongated, the impeller radially contracts and axially elongates. Other applications are also described.