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公开(公告)号：US20240138734A1
公开(公告)日：2024-05-02
申请号：US18407010
申请日：2024-01-08
CPC分类号： A61B5/150946 , A61B5/15003 , A61B5/150099 , A61B5/150213 , A61B5/150221 , A61B5/150251 , A61B5/150992 , B01L3/502 , B01L2200/026 , B01L2200/027 , B01L2200/0684 , B01L2200/0689 , B01L2200/141 , B01L2300/0681 , B01L2300/14 , B01L2400/0478 , B01L2400/0487
摘要： A fluid control device includes an inlet configured to be placed directly or indirectly in fluid communication with a bodily fluid source and an outlet configured to be placed in fluid communication with a fluid collection device. The fluid control device has a first state in which a negative pressure differential produced from an external source such as the fluid collection device is applied to the fluid control device to draw an initial volume of bodily fluid from the bodily fluid source, through the inlet, and into a sequestration portion of the fluid control device. The fluid control device has a second state in which (1) the sequestration portion sequesters the initial volume, and (2) the negative pressure differential draws a subsequent volume of bodily fluid, being substantially free of contaminants, from the bodily fluid source, through the fluid control device, and into the fluid collection device.
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公开(公告)号：US20230248281A1
公开(公告)日：2023-08-10
申请号：US18299680
申请日：2023-04-12
IPC分类号： A61B5/15
CPC分类号： A61B5/150946 , A61B5/150099 , A61B5/150251 , A61B5/15003 , A61B5/150221 , A61B5/150213 , B01L3/502 , A61B5/150992 , B01L2400/0478 , B01L2300/14 , B01L2400/0487 , B01L2200/141 , B01L2200/0689 , B01L2200/026 , B01L2200/027 , B01L2200/0684 , B01L2300/0681
摘要： A fluid control device includes an inlet configured to be placed directly or indirectly in fluid communication with a bodily fluid source and an outlet configured to be placed in fluid communication with a fluid collection device. The fluid control device has a first state in which a negative pressure differential produced from an external source such as the fluid collection device is applied to the fluid control device to draw an initial volume of bodily fluid from the bodily fluid source, through the inlet, and into a sequestration portion of the fluid control device. The fluid control device has a second state in which (1) the sequestration portion sequesters the initial volume, and (2) the negative pressure differential draws a subsequent volume of bodily fluid, being substantially free of contaminants, from the bodily fluid source, through the fluid control device, and into the fluid collection device.
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公开(公告)号：US20230063558A1
公开(公告)日：2023-03-02
申请号：US17902207
申请日：2022-09-02
摘要： A fluid transfer device for parenterally transferring fluid to and/or from a patient includes a housing, a needle, and an occlusion mechanism. The housing defines a fluid flow path and is couplable to a fluid reservoir. The needle has a distal end portion that is configured to be inserted into the patient and a proximal end portion that is configured to be fluidically coupled to the fluid flow path of the housing, and defines a lumen therebetween. The occlusion mechanism selectively controls a fluid flow between the needle and the fluid flow path. The occlusion mechanism includes an occlusion member that is movable between a first configuration where the lumen of the needle is obstructed during insertion into the patient and a second configuration where the lumen of the needle is unobstructed after the needle has been inserted into the patient allowing fluid transfer to or from the patient.
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公开(公告)号：US20220369971A1
公开(公告)日：2022-11-24
申请号：US17583791
申请日：2022-01-25
摘要： An apparatus includes a pre-sample reservoir, a diversion mechanism, and a flow metering mechanism. The diversion mechanism has an inlet port couplable to a lumen-defining device to receive bodily-fluids from a patient, a first outlet port fluidically couplable to the pre-sample reservoir, and a second outlet port fluidically couplable to a sample reservoir. The diversion mechanism defines a first fluid flow path and a second flow path that are configured to place the first outlet port and the second outlet port, respectively, in fluid communication with the inlet port. The flow metering mechanism is configured to meter a flow of a predetermined volume of bodily-fluid through the first fluid flow path into the pre-sample reservoir, to meter a flow of a second volume of bodily-fluid through the second fluid flow path into the sample reservoir, and to display a volumetric indicator associated with the predetermined volume and the second volume.
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公开(公告)号：US20220218250A1
公开(公告)日：2022-07-14
申请号：US17710411
申请日：2022-03-31
摘要： A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.
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公开(公告)号：US20220151525A1
公开(公告)日：2022-05-19
申请号：US17403500
申请日：2021-08-16
摘要： An apparatus includes an inlet configured to be placed in fluid communication with a bodily fluid source and an outlet configured to be placed in fluid communication with a fluid collection device. A sequestration portion can be configured to receive an initial volume of bodily fluid. A flow controller disposed in the sequestration portion can be configured to transition from a first state to a second state in response to contact with the initial volume of bodily fluid. As the flow controller transitions, a negative pressure differential can be defined that is operable to draw the initial volume of bodily fluid into the sequestration portion. When the flow controller is in the second state, the negative pressure differential can be substantially equalized such that (1) the sequestration portion sequesters the initial volume and (2) a subsequent volume of bodily fluid can be transferred from the inlet to the outlet.
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公开(公告)号：US20200289039A1
公开(公告)日：2020-09-17
申请号：US16815526
申请日：2020-03-11
摘要： An apparatus for procuring bodily fluid samples with reduced contamination includes a housing having a sequestration chamber, an inlet, and an outlet. A flow controller defines a portion of the sequestration chamber and can transition—in response to a suction force exerted by a fluid collection device fluidically coupled to the outlet—from a first state in which the sequestration chamber has a first volume to a second state in which the sequestration chamber has a second volume greater than the first volume, to draw an initial volume of bodily fluid into the sequestration chamber. An actuator is coupled to the housing and is in fluid communication with the inlet and the sequestration chamber in a first configuration, and is transitioned to a second configuration to sequester the sequestration chamber from the inlet, and allow a subsequent volume of bodily fluid to flow from the inlet to the outlet.
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公开(公告)号：US20190175085A1
公开(公告)日：2019-06-13
申请号：US16274835
申请日：2019-02-13
摘要： An apparatus includes a pre-sample reservoir, a diversion mechanism, and a flow metering mechanism. The diversion mechanism has an inlet port couplable to a lumen-defining device to receive bodily-fluids from a patient, a first outlet port fluidically couplable to the pre-sample reservoir, and a second outlet port fluidically couplable to a sample reservoir. The diversion mechanism defines a first fluid flow path and a second flow path that are configured to place the first outlet port and the second outlet port, respectively, in fluid communication with the inlet port. The flow metering mechanism is configured to meter a flow of a predetermined volume of bodily-fluid through the first fluid flow path into the pre-sample reservoir, to meter a flow of a second volume of bodily-fluid through the second fluid flow path into the sample reservoir, and to display a volumetric indicator associated with the predetermined volume and the second volume.
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公开(公告)号：US20160113560A1
公开(公告)日：2016-04-28
申请号：US14926784
申请日：2015-10-29
CPC分类号： A61B5/150221 , A61B5/150099 , A61B5/150236 , A61B5/150244 , A61B5/150916 , A61B5/153 , A61B5/154 , A61B10/0045 , A61B10/0096
摘要： A device includes a pre-sample reservoir, an actuator mechanism, and a diverter. The pre-sample reservoir can be fluidically coupled to a delivery member to receive and isolate a predetermined volume of bodily-fluid withdrawn from a patient. The actuator mechanism is operably coupled to the pre-sample reservoir such that, when actuated, a negative pressure is formed in the pre-sample reservoir that urges the bodily-fluid to flow into the pre-sample reservoir. The diverter can selectively control fluid flow between the delivery member and the pre-sample reservoir. The diverter includes a flow control mechanism that defines a first fluid flow path and a second fluid flow path. The diverter is movable between a first configuration in which the bodily-fluid flows through the first fluid flow path to the pre-sample reservoir, and a second configuration in which the bodily-fluid flows through the second fluid flow path to a sample reservoir coupled to the diverter.
摘要翻译： 一种装置包括一个预样品贮存器，一个致动器机构和一个转向器。 预样品储存器可以流体耦合到递送构件以接收和隔离从患者抽出的预定体积的体液。 致动器机构可操作地联接到预样品储存器，使得当致动时，在样品前储存器中形成负压，其促使体液流入预样品储存器。 分流器可以选择性地控制输送构件和预样品储存器之间的流体流动。 分流器包括限定第一流体流动路径和第二流体流动路径的流量控制机构。 所述分流器可在其中所述体液流过所述第一流体流动路径与所述预采样容器之间的第一构型和第二构造中移动，其中所述体液流过所述第二流体流动路径， 到分流器
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公开(公告)号：US20240306963A1
公开(公告)日：2024-09-19
申请号：US18675824
申请日：2024-05-28
CPC分类号： A61B5/150221 , A61B5/1405 , A61B5/150099 , A61B5/150229 , A61B5/150236 , A61B5/150251 , A61B5/150946 , A61B5/150992 , A61B5/153 , A61B5/15003
摘要： An apparatus includes a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing defines an inner volume and has an inlet port that can be fluidically coupled to a patient and an outlet port. The fluid reservoir is disposed in the inner volume to receive and isolate a first volume of a bodily-fluid. The flow control mechanism is rotatable in the housing from a first configuration, in which a first lumen places the inlet port is in fluid communication with the fluid reservoir, and a second configuration, in which a second lumen places the inlet port in fluid communication with the outlet port. The actuator is configured to create a negative pressure in the fluid reservoir and is configured to rotate the flow control mechanism from the first configuration to the second configuration after the first volume of bodily-fluid is received in the fluid reservoir.
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