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    Inter-region thermal complementary system by distributed cryogenic and thermal devices
    1.
    发明授权
    Inter-region thermal complementary system by distributed cryogenic and thermal devices 失效
    分布式低温和热装置的区域间互补系统

    公开(公告)号：US06889520B2

    公开(公告)日：2005-05-10

    申请号：US10416487

    申请日：2001-12-12

    申请人： Makoto Sano ,  Kuniaki Kawamura ,  Junji Matsuda ,  Katsumi Fujima ,  Takanori Kudo ,  Youichi Kawazu ,  Choiku Yoshikawa ,  Syuji Fukano

    发明人： Makoto Sano ,  Kuniaki Kawamura ,  Junji Matsuda ,  Katsumi Fujima ,  Takanori Kudo ,  Youichi Kawazu ,  Choiku Yoshikawa ,  Syuji Fukano

    IPC分类号： F25D17/02 ,  F25B27/00 ,  F25D11/00

    CPC分类号： F25D17/02 ,  F24F2005/0039

    摘要： The object of the invention is to provide a thermal complementary (combination of heat supply and heat discharge) system which can complement heat without the restriction of area of a region to be supplied with heat. An endless multiplex helical loop is formed to complement the heat produced in a region such as plants and regional facilities on a reciprocal basis, and the water is not circulated forcibly but achieves heat transfer in the helical loop.Liquid or slurry-like water is sealed in the annular endless channel (endless loop) without forcibly circulated. Therefore, loop diameter of the annular endless channel, that means the area of the region, is not limited. The water forms temperature zones in the endless helical loop, the temperature being different per each component loop. Distributed cryogenic sources and thermal sources are thermally connected to said multiplex helical loop so that heat (i.e. water) can be taken in or discharged to or from said cryogenic or thermal sources. As the water needs not be forcibly circulated, the power for forcibly circulating the water is eliminated resulting in reduced running cost. Refrigerating apparatuses, heat source apparatuses, etc. distributed in the region are effectively utilized and also central control of energy supply through the multiplex helical loops is made possible.

    摘要翻译： 本发明的目的是提供一种热互补（组合的热供应和放热）系统，其可以补充热量，而不受限于供热区域的面积。 形成一个无休止的多路复用螺旋回路，以互补的方式补充在诸如工厂和区域设施之类的区域产生的热量，水不会被强制循环，而是在螺旋回路中实现热传递。 液体或浆状水被密封在环形环形通道（无限循环）中，而不会被强制循环。 因此，环形环形通道的环径，即区域的面积不受限制。 水在环形螺旋环中形成温度区，每个组分环的温度不同。 分布式低温源和热源热连接到所述多路螺旋回路，使得热（即水）可以被吸入或从所述低温或热源排出。 由于水不需要强制循环，所以强制循环水的功率被消除，导致运行成本降低。 有效利用分布在该区域的制冷装置，热源装置等，并且也可以通过多路复用螺旋回路进行能量供给的集中控制。

    Remedies for sepsis
    2.
    发明授权
    Remedies for sepsis 失效
    败血症的治疗方法

    公开(公告)号：US07652025B2

    公开(公告)日：2010-01-26

    申请号：US10477062

    申请日：2002-05-08

    申请人： Tomohiko Suzuki ,  Hideaki Inada ,  Yoshitaka Yoshizawa ,  Kuniaki Kawamura ,  Toshiaki Tanaka

    发明人： Tomohiko Suzuki ,  Hideaki Inada ,  Yoshitaka Yoshizawa ,  Kuniaki Kawamura ,  Toshiaki Tanaka

    IPC分类号： A01N43/42 ,  A61K31/44

    CPC分类号： A61K31/40 ,  A61K31/485 ,  A61K38/00 ,  C07D489/08 ,  C07K5/1016

    摘要： A therapeutic agent for sepsis and various symptoms accompanying sepsis (such as septic shock, disseminated intravascular coagulation syndrome, adult respiratory distress syndrome and multiple organ dysfunction) is disclosed. The therapeutic agent for sepsis according to the present invention comprises as an effective ingredient an opioid κ receptor agonist compound such as (−)-17-(cyclopropylmethyl)-3,14β-dihydroxy-4,5α-epoxy-6β[N-methyl-trans-3-(3-furyl)acrylamide] oxide derivative. The opioid κ receptor agonist compound may be administered as it is or in the form of a pharmaceutical composition prepared by mixing the compound with a known pharmaceutically acceptable acid, carrier or vehicle orally or parenterally.

    摘要翻译： 公开了脓毒症和伴随脓毒症的各种症状的治疗剂（例如脓毒性休克，弥散性血管内凝血综合征，成人呼吸窘迫综合征和多器官功能障碍）。 根据本发明的败血症治疗剂包括作为有效成分的阿片样物质κ受体激动剂化合物，例如（ - ） - 17-（环丙基甲基）-3,14β-二羟基-4,5α-环氧-6β-[N-甲基 （3-呋喃基）丙烯酰胺]氧化物衍生物。 阿片样物质κ受体激动剂化合物可以原样或以通过将化合物与已知的药学上可接受的酸，载体或载体口服或胃肠外混合制备的药物组合物的形式进行给药。

    Coal energy utilization system having superconducting power transmission
    6.
    发明授权
    Coal energy utilization system having superconducting power transmission 失效
    具有超导功率传输的煤能利用系统

    公开(公告)号：US07602085B2

    公开(公告)日：2009-10-13

    申请号：US11195853

    申请日：2005-08-03

    申请人： Kuniaki Kawamura ,  Masamitsu Ikeuchi ,  Akito Machida

    发明人： Kuniaki Kawamura ,  Masamitsu Ikeuchi ,  Akito Machida

    IPC分类号： G05F3/06

    CPC分类号： H02J3/36 ,  H02G15/34 ,  H02J3/38 ,  H02J3/381 ,  Y02E40/60 ,  Y02E40/648 ,  Y02E60/60

    摘要： A system for utilizing coal energy includes a thermal power generator near a coal field area that converts coal energy of the coal field area located remotely from a demand end to electric energy. It also includes an alternating current load at a demand end side, an alternating current power distribution network, and an electric power transmission mechanism that transmit electric energy from the thermal power generator to the power distribution network. The electric power transmission mechanism is a combination of super conductive power transmitting system that transmit direct current electricity with small transmission loss utilizing super conductive power transmitting cables and a conventional power distribution network operating at ambient temperatures.

    摘要翻译： 利用煤能的系统包括靠近煤田区域的火力发电机，其将远离需求端的煤田区域的煤能转化为电能。 它还包括在需求端侧的交流负载，交流配电网络和将电能从火力发电机传输到配电网络的电力传输机构。 电力传输机构是超导电功率传输系统的组合，其使用超导电输电电缆和常规的在环境温度下工作的配电网络传输直流电和小传输损耗。

    Apparatus for producing slush nitrogen and method for producing the same
    7.
    发明授权
    Apparatus for producing slush nitrogen and method for producing the same 失效
    硫化氮生产装置及其制造方法

    公开(公告)号：US07155930B2

    公开(公告)日：2007-01-02

    申请号：US11165528

    申请日：2005-06-23

    申请人： Kuniaki Kawamura ,  Akito Machida ,  Masamitsu Ikeuchi ,  Kazuhiro Hattori ,  Kouichi Matsuo ,  Hideharu Yanagi

    发明人： Kuniaki Kawamura ,  Akito Machida ,  Masamitsu Ikeuchi ,  Kazuhiro Hattori ,  Kouichi Matsuo ,  Hideharu Yanagi

    IPC分类号： F25J1/00 ,  F17C5/00

    CPC分类号： F25J1/0015 ,  F25C1/00 ,  F25D3/10 ,  F25J1/0221 ,  F25J1/0251 ,  F25J1/0276 ,  F25J2205/20 ,  F25J2205/30 ,  F25J2205/90 ,  F25J2210/42 ,  F25J2240/60

    摘要： Liquid nitrogen is filled in a low temperature vessel; an ejector that sucks liquid nitrogen by blowing a cooling agent (liquid or gas) such as low temperature helium gas or liquid helium of pressure higher than in the space within the vessel is disposed in the vessel; the liquid nitrogen blown with the cooling agent is cooled by the cooling agent to become fine particles of solid nitrogen which fall down; and gas in a space of the vessel is discharged out of the vessel so as to maintain the pressure of the space higher than the atmospheric pressure.A gaseous phase of liquid nitrogen in an adiabatic vessel is depressurized to vaporize nitrogen in a liquid phase so that a temperature of the nitrogen is reached to the triple point of nitrogen by lowering temperature thereby and solid nitrogen is produced by keeping at the triple point, and that the produced solid nitrogen is transformed into slush by stirring the content of the adiabatic vessel.In a method for cooling a super conductive body in which a material showing a state of super conductance in the vicinity of the temperature of liquid nitrogen or of the temperature liquid nitrogen and solid nitrogen coexist is used, a method for cooling a super conductive body characterized in that the super conductive body is immersed in slush nitrogen held in an adiabatic vessel, and that the body is contacted with slush nitrogen to cool.

    摘要翻译： 液氮填充在低温容器中; 喷射器通过吹送诸如低温氦气或低于容器内的空间的压力的液氦的冷却剂（液体或气体）而吸入液氮; 用冷却剂吹入的液氮被冷却剂冷却，成为脱落的固体氮的细小颗粒; 并且将容器的空间中的气体排出容器，以保持空间的压力高于大气压力。 将绝热容器中的氮气气相减压以使液相中的氮气蒸发，由此通过降低温度将氮气的温度达到氮的三分之一，由此通过保持三相点产生固体氮， 并且通过搅拌绝热容器的内容物将所产生的固体氮转变成泥浆。 在使用在液氮温度或液氮附近存在超导状态的材料和固体氮共存的超导电体的冷却方法中，使用超导电体的冷却方法， 因为超导体被浸入保持在绝热容器中的冰冷的氮气中，并且使主体与冷却氮气接触以冷却。

    Coal energy utilization system having superconducting power transmission
    8.
    发明申请
    Coal energy utilization system having superconducting power transmission 失效
    具有超导功率传输的煤能利用系统

    公开(公告)号：US20060056120A1

    公开(公告)日：2006-03-16

    申请号：US11195853

    申请日：2005-08-03

    申请人： Kuniaki Kawamura ,  Masamitsu Ikeuchi ,  Akito Machida

    发明人： Kuniaki Kawamura ,  Masamitsu Ikeuchi ,  Akito Machida

    IPC分类号： H02H7/00

    CPC分类号： H02J3/36 ,  H02G15/34 ,  H02J3/38 ,  H02J3/381 ,  Y02E40/60 ,  Y02E40/648 ,  Y02E60/60

    摘要： A system for utilizing coal energy includes a thermal power generator near a coal field area that converts coal energy of the coal field area located remotely from a demand end to electric energy. It also includes an alternating current load at a demand end side, an alternating current power distribution network, and an electric power transmission mechanism that transmit electric energy from the thermal power generator to the power distribution network. The electric power transmission mechanism is a combination of super conductive power transmitting system that transmit direct current electricity with small transmission loss utilizing super conductive power transmitting cables and a conventional power distribution network operating at ambient temperatures. Electricity is transmitted to the demand end through the alternating current power distribution network by converting alternating current at a feeding point of the power distribution network where the current is fed with an alternating current converting mechanism provided at the connecting end.

    摘要翻译： 利用煤能的系统包括靠近煤田区域的火力发电机，其将远离需求端的煤田区域的煤能转化为电能。 它还包括在需求端侧的交流负载，交流配电网络和将电能从火力发电机传输到配电网络的电力传输机构。 电力传输机构是超导电功率传输系统的组合，其使用超导电输电电缆和常规的在环境温度下工作的配电网络传输直流电和小传输损耗。 通过交流配电网络将电流传送到需求端，通过在配电网的馈电点处转换交流电，其中电流被馈送在设置在连接端的交流电转换机构。

    Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group
    9.
    发明申请
    Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group 有权
    尿频或尿失禁的补救措施或预防措施以及含有氮杂环基的吗啡喃衍生物

    公开(公告)号：US20060040970A1

    公开(公告)日：2006-02-23

    申请号：US10530664

    申请日：2003-10-08

    申请人： Naoki Izumimoto ,  Koji Kawai ,  Kuniaki Kawamura ,  Morihiro Fujimura ,  Toshikazu Komagata

    发明人： Naoki Izumimoto ,  Koji Kawai ,  Kuniaki Kawamura ,  Morihiro Fujimura ,  Toshikazu Komagata

    IPC分类号： A61K31/473

    CPC分类号： C07D489/08

    摘要： The invention provides a morphinan derivative of the Formula (I): (wherein R1 is methyl, cyclopropylmethyl or the like; R2 and R3 are hydroxy, methoxy, acetoxy or the like; both Y and Z are valence bonds, —C(═O)— or the like; X is C2-C5 carbon chain (one of the carbon atoms may be substituted by oxygen, sulfur or nitrogen) constituting a part of the ring structure, or the like; (R4)k is substituted or non-substituted benzene fused ring, carbonyl group or the like; R9 is hydrogen or the like; R10 and R11 are bound to represent —O—, or the like, and R6 is hydrogen or the like) or a pharmaceutically acceptable acid addition salt thereof. The invention also provides a therapeutic or prophylactic agent for urinary frequency or urinary incontinence, comprising as an effective ingredient the morphinan derivative or the pharmaceutically acceptable acid addition salt thereof; a method for therapy or prophylaxis of the diseases.

    摘要翻译： 本发明提供式（I）的吗啡喃衍生物：其中R 1是甲基，环丙基甲基等; R 2和R 3 O >是羟基，甲氧基，乙酰氧基等; Y和Z都是价键，-C（-O） - 等; X是C 2 -C 5 构成环结构的一部分的碳链（其中一个碳原子可以被氧，硫或氮取代）等;（R 4） 是取代或未取代的苯稠环，羰基等; R 9是氢等; R 10和R 11， 必须代表-O-等，R 6是氢等）或其药学上可接受的酸加成盐。 本发明还提供了用于尿频或尿失禁的治疗或预防剂，其包含吗啡喃衍生物或其药学上可接受的酸加成盐作为有效成分; 一种治疗或预​​防疾病的方法。