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1.发明授权Hand held micro PCR device including microcontroller for exchanging information with a communications interface 有权手持式微PCR装置，包括用于与通信接口交换信息的微控制器公开(公告)号：US09370774B2
公开(公告)日：2016-06-21
申请号：US12682555
申请日：2008-10-13
申请人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah , Sudip Mondal , Venkatakrishnan Venkataraman
发明人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah , Sudip Mondal , Venkatakrishnan Venkataraman
CPC分类号： B01L7/52 , B01L3/5027 , B01L2300/0627 , B01L2300/0851 , B01L2300/0887 , B01L2300/16 , B01L2300/1805
摘要： Instant invention is about a hand held micro PCR device comprising a LTCC micro PCR chip comprising a heater, a reaction chamber to load a sample. It also comprises a heater control to regulate the heater on basis of input received from a temperature sensor. It further has an optical system having an optical fiber to detect a fluorescence signal from the sample, and at least one communication interface to interact with other device(s).
摘要翻译： 本发明涉及一种手持式微PCR装置，其包含LTCC微PCR芯片，其包括加热器，负载样品的反应室。 它还包括加热器控制，以根据从温度传感器接收的输入来调节加热器。 它还具有光学系统，其具有用于检测来自样品的荧光信号的光纤，以及至少一个通信接口以与其他设备相互作用。
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公开(公告)号：US09044754B2
公开(公告)日：2015-06-02
申请号：US12682581
申请日：2008-10-13
申请人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah
发明人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah
CPC分类号： B01L7/52 , B01L3/5027 , B01L2300/0627 , B01L2300/0851 , B01L2300/0887 , B01L2300/16 , B01L2300/1805
摘要： Instant invention is about a micro chip comprising plurality of layers of LTCC wherein a reaction chamber is formed in plurality of top layers to load samples. A heater embedded in at least one of the layers below the reaction chamber and a temperature sensor is embedded in at least one of the layers between the heater and the reaction chamber for analyzing the sample. The temperature sensor can be placed outside the chip to measure the chip temperature.
摘要翻译： 即时发明是关于包括多层LTCC的微芯片，其中反应室形成在多个顶层中以加载样品。 嵌入在反应室下面的至少一个层的加热器和温度传感器被嵌入在加热器和反应室之间的至少一个层中，用于分析样品。 温度传感器可以放置在芯片外部以测量芯片温度。
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公开(公告)号：US20120045761A1
公开(公告)日：2012-02-23
申请号：US13203286
申请日：2010-02-23
IPC分类号： C12Q1/68
CPC分类号： C12Q1/701 , C12Q2561/101 , C12Q2561/113 , Y02A50/51
摘要： The present disclosure gives a detailed description of methods for determining the presence of Chikungunya viral nucleic acids in blood/serum/plasma samples by employing “Oligonucleotide” probes. The designed “Oligonucleotide” probes can be used for qualitative or quantitative detection of Chikungunya virus in an infected sample by employing Real time PCR.
摘要翻译： 本公开详细描述了通过使用“寡核苷酸”探针来测定血液/血清/血浆样品中基孔肯雅病毒核酸的存在的方法。 设计的“寡核苷酸”探针可用于通过采用实时PCR定性或定量检测感染样品中基孔肯雅病毒。
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公开(公告)号：US20130130235A1
公开(公告)日：2013-05-23
申请号：US13812863
申请日：2011-07-15
申请人： Manjula Jagannath , Manoj Mulakkapurath Narayanan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao
发明人： Manjula Jagannath , Manoj Mulakkapurath Narayanan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao
IPC分类号： C12Q1/70
CPC分类号： C12Q1/701
摘要： The present disclosure gives description of a method used for the detection and quantification of dengue viral infection caused by dengue virus using nucleic acids isolated from blood, plasma or serum samples by employing Oligonucleotide probes. The method employed here for detection is by Real time PCR. The instant disclosure also provides for primers, probes, PCR Reaction mixture and kit thereof.
摘要翻译： 本公开描述了使用通过使用寡核苷酸探针从血液，血浆或血清样品分离的核酸来检测和定量由登革热病毒引起的登革热病毒感染的方法的描述。 这里用于检测的方法是通过实时PCR。 本公开还提供了引物，探针，PCR反应混合物及其试剂盒。
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公开(公告)号：US20100240044A1
公开(公告)日：2010-09-23
申请号：US12682581
申请日：2008-10-13
申请人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah
发明人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah
CPC分类号： B01L7/52 , B01L3/5027 , B01L2300/0627 , B01L2300/0851 , B01L2300/0887 , B01L2300/16 , B01L2300/1805
摘要： Instant invention is about a micro chip comprising plurality of layers of LTCC wherein a reaction chamber is formed in plurality of top layers to load samples. A heater embedded in at least one of the layers below the reaction chamber and a temperature sensor is embedded in at least one of the layers between the heater and the reaction chamber for analyzing the sample. The temperature sensor can be placed outside the chip to measure the chip temperature.
摘要翻译： 即时发明是关于包括多层LTCC的微芯片，其中反应室形成在多个顶层中以加载样品。 嵌入在反应室下面的至少一个层的加热器和温度传感器被嵌入在加热器和反应室之间的至少一个层中，用于分析样品。 温度传感器可以放置在芯片外部以测量芯片温度。
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公开(公告)号：US20110306046A1
公开(公告)日：2011-12-15
申请号：US13202842
申请日：2010-01-27
申请人： Manjula Jagannath , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Mulakkapurath Narayanan Manoj , Shamamandri Markandaiah Shashirekha
发明人： Manjula Jagannath , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Mulakkapurath Narayanan Manoj , Shamamandri Markandaiah Shashirekha
CPC分类号： C12Q1/6893 , Y02A50/58
摘要： The present disclosure gives description of a method used for the detection and quantification of malarial infection caused either by Plasmodium falciparum or Plasmodium vivax using nucleic acids isolated from blood samples by employing Oligonucleotide probes. The method employed here for detection is by Real time PCR.
摘要翻译： 本公开描述了使用通过使用寡核苷酸探针从血液样品分离的核酸来检测和定量由恶性疟原虫或间日疟原虫引起的疟疾感染的方法的描述。 这里用于检测的方法是通过实时PCR。
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公开(公告)号：US20100297640A1
公开(公告)日：2010-11-25
申请号：US12682555
申请日：2008-10-13
申请人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanaihan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah , Sudip Mondal , Venkatakrishnan Venkataraman
发明人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanaihan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah , Sudip Mondal , Venkatakrishnan Venkataraman
CPC分类号： B01L7/52 , B01L3/5027 , B01L2300/0627 , B01L2300/0851 , B01L2300/0887 , B01L2300/16 , B01L2300/1805
摘要： Instant invention is about a hand held micro PCR device comprising a LTCC micro PCR chip comprising a heater, a reaction chamber to load a sample. It also comprises a heater control to regulate the heater on basis of input received from a temperature sensor. It further has an optical system having an optical fiber to detect a fluorescence signal from the sample, and at least one communication interface to interact with other device(s).
摘要翻译： 本发明涉及一种手持式微PCR装置，其包含LTCC微PCR芯片，其包括加热器，负载样品的反应室。 它还包括加热器控制，以根据从温度传感器接收的输入来调节加热器。 它还具有光学系统，其具有用于检测来自样品的荧光信号的光纤，以及至少一个通信接口以与其他设备相互作用。
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