公开(公告)号：US06736978B1

公开(公告)日：2004-05-18

申请号：US10017467

申请日：2001-12-13

申请人： Marc D. Porter ,  Jing Ni ,  G. Brent Dawson ,  Ruth Shinar ,  Robert J. Lipert ,  Michael C. Granger ,  Mark Tondra

发明人： Marc D. Porter ,  Jing Ni ,  G. Brent Dawson ,  Ruth Shinar ,  Robert J. Lipert ,  Michael C. Granger ,  Mark Tondra

IPC分类号： G01N33553

CPC分类号： G01F1/708 ,  G01N33/54333 ,  Y10S436/806

摘要： Method and apparatus for manipulating and monitoring analyte flowing in fluid streams. A giant magnetoresistive sensor has an array of sensing elements that produce electrical output signals which vary in dependence on changes in the magnetic field proximate the sensing elements. The analyte is included in a stream, such that the stream has a magnetic property which is dependent on the concentration and distribution on the analyte therein. The stream is flowed past the giant magnetoresistive sensor and in sufficiently close proximity to cause the magnetic properties of the stream to produce electrical output signals. The electrical output signals are monitored as an indicator of analyte concentration or distribution in the stream flowing past the GMR sensor. Changes in the magnetic field produced by the background stream are introduced by analyte molecules, whose presence in the flow past the GMR will effect the output reading.

摘要翻译： 用于操纵和监测在流体流中流动的分析物的方法和装置。 巨磁阻传感器具有产生电输出信号的感测元件的阵列，该电输出信号根据感测元件附近的磁场的变化而变化。 分析物被包含在流中，使得流具有取决于其上的分析物的浓度和分布的磁性。 流流过巨磁电阻传感​​器并且足够靠近以使流的磁特性产生电输出信号。 监测电输出信号作为流过GMR传感器的流中分析物浓度或分布的指标。 由背景流产生的磁场的变化由分析物分子引入，其在流过GMR的流中的存在将影响输出读数。

公开(公告)号：US07179383B1

公开(公告)日：2007-02-20

申请号：US10793058

申请日：2004-03-04

申请人： Marc D Porter ,  Jing Ni ,  G Brent Dawson ,  Ruth Shinar ,  Robert J Lipert ,  Michael C Granger ,  Mark Tondra

发明人： Marc D Porter ,  Jing Ni ,  G Brent Dawson ,  Ruth Shinar ,  Robert J Lipert ,  Michael C Granger ,  Mark Tondra

IPC分类号： B03C1/00 ,  G01N33/553

CPC分类号： G01F1/708 ,  G01N33/54333 ,  Y10S436/806

摘要： Method and apparatus for manipulating and monitoring analyte flowing in fluid streams. A giant magnetoresistive sensor has an array of sensing elements that produce electrical output signals which vary in dependence on changes in the magnetic field proximate the sensing elements. The analyte is included in a stream, such that the stream has a magnetic property which is dependent on the concentration and distribution on the analyte therein. The stream is flowed past the giant magnetoresistive sensor and in sufficiently close proximity to cause the magnetic properties of the stream to produce electrical output signals. The electrical output signals are monitored as an indicator of analyte concentration or distribution in the stream flowing past the GMR sensor. Changes in the magnetic field produced by the background stream are introduced by analyte molecules, whose presence in the flow past the GMR will effect the output reading.

摘要翻译： 用于操纵和监测在流体流中流动的分析物的方法和装置。 巨磁阻传感器具有产生电输出信号的感测元件的阵列，该电输出信号根据感测元件附近的磁场的变化而变化。 分析物被包含在流中，使得流具有取决于其上的分析物的浓度和分布的磁性。 流流过巨磁电阻传感​​器并且足够靠近以使流的磁特性产生电输出信号。 监测电输出信号作为流过GMR传感器的流中分析物浓度或分布的指标。 由背景流产生的磁场的变化由分析物分子引入，其在流过GMR的流中的存在将影响输出读数。

公开(公告)号：US06237397B1

公开(公告)日：2001-05-29

申请号：US09413628

申请日：1999-10-06

申请人： Ruth Shinar ,  Guojun Liu ,  Marc D. Porter

发明人： Ruth Shinar ,  Guojun Liu ,  Marc D. Porter

IPC分类号： G01N2902

CPC分类号： G01N29/022 ,  G01N2291/014 ,  G01N2291/0256 ,  G01N2291/02863 ,  G01N2291/0423 ,  G01N2291/0426 ,  G01N2291/0427

摘要： An acoustic wave based-chemical sensor containing a crystal substrate and a coating of small particulate matter is disclosed. The small particulate matter can be graphite particles. Transducers are connected to the crystal substrate to generate an alternating potential across the crystal substrate, which in turn causes the crystal to resonate due to the converse piezoelectric effect. The coating absorbs the analyte, thus changing the mass of the sensor, and accordingly changing its resonant frequency. The transducers detect this change in resonant frequency to indicate that the analyte is present. The use of small particulate matter results in a coating having a large surface area which facilitates mass uptake of large amounts of VOCs, improved acoustic properties even with relatively thick coatings, and a high operational temperature range.

摘要翻译： 公开了一种包含晶体衬底和小颗粒物质涂层的基于声波的化学传感器。 小颗粒物可以是石墨颗粒。 传感器连接到晶体衬底以在晶体衬底之间产生交替电位，这又导致晶体由于相反的压电效应而谐振。 涂层吸收分析物，从而改变传感器的质量，从而改变其共振频率。 传感器检测谐振频率的这种变化，以表明分析物存在。 使用小的颗粒物质可形成具有大表面积的涂层，其有利于大量挥发性有机物的吸收，甚至在相对较厚的涂层和较高的操作温度范围内也改善了声学性能。

公开(公告)号：US06432362B1

公开(公告)日：2002-08-13

申请号：US09413401

申请日：1999-10-06

申请人： Ruth Shinar ,  Guojun Liu ,  Marc D. Porter

发明人： Ruth Shinar ,  Guojun Liu ,  Marc D. Porter

IPC分类号： G01N2700

CPC分类号： G01N29/022 ,  G01N2291/014 ,  G01N2291/0212 ,  G01N2291/0222 ,  G01N2291/0256 ,  G01N2291/0423 ,  G01N2291/0426 ,  G01N2291/0427

摘要： An acoustic wave based-chemical sensor utilizing a crystal substrate and a coating of at least two blended materials is disclosed. The blended materials comprise a combination of (a) a high glass transition temperature polymer or a material of high melting point, and (b) a low glass transition temperature polymer or a material having a low melting point. Transducers are connected to the crystal substrate to generate an alternating potential across the crystal substrate, which in turn causes the crystal to resonate due to the converse piezoelectric effect. The blended coating absorbs the analyte, thus changing the mass of the chemical sensor, and accordingly changing its resonant frequency. The transducers detect this change in resonant frequency to indicate that the analyte is present. The use of blended materials results in a thicker coating combining the preferred properties of the blend constituents, such as improved detection sensitivities, faster response times, less acoustic wave damping, and higher operational temperature ranges.

摘要翻译： 公开了一种使用晶体基底的基于声波的化学传感器和至少两种混合材料的涂层。 混合材料包括（a）高玻璃化转变温度聚合物或高熔点材料的组合，和（b）低玻璃化转变温度聚合物或具有低熔点的材料。 传感器连接到晶体衬底以在晶体衬底之间产生交替电位，这又导致晶体由于相反的压电效应而谐振。 混合涂层吸收分析物，从而改变化学传感器的质量，从而改变其共振频率。 传感器检测谐振频率的这种变化，以表明分析物存在。 混合材料的使用导致较厚的涂层结合混合物组分的优选性能，例如改进的检测灵敏度，更快的响应时间，更少的声波阻尼和更高的操作温度范围。

公开(公告)号：US07718130B1

公开(公告)日：2010-05-18

申请号：US11401274

申请日：2006-04-11

申请人： Ruth Shinar ,  Joseph Shinar ,  Vikram L. Dalal

发明人： Ruth Shinar ,  Joseph Shinar ,  Vikram L. Dalal

IPC分类号： G01N21/64 ,  G01N21/00 ,  F21V9/16 ,  G01N21/76 ,  G02B6/00

CPC分类号： G01N21/6454 ,  B01L3/5027 ,  G01N2201/0628

摘要： Integrated photoluminescence (PL)-based chemical and biological sensors are provided comprising a photodetector (PD), a long-pass filter, an excitation source, and a sensing element, all based on thin films or structures. In one embodiment the light source is an organic light emitting device (OLED) and the sensing element is based on thin films or solutions in microfluidic channels or wells. The PD and optical filters are based on thin film amorphous or nanocrystalline silicon and related materials. In another embodiment, sensor components are fabricated on transparent substrates, which are attached back-to-back to generate a compact, integrated structure.

摘要翻译： 提供基于集成光致发光（PL）的化学和生物传感器，其包括基于薄膜或结构的光电检测器（PD），长通滤波器，激发源和感测元件。 在一个实施例中，光源是有机发光器件（OLED），并且感测元件基于微流体通道或孔中的薄膜或溶液。 PD和滤光器基于薄膜非晶或纳米晶硅及相关材料。 在另一个实施例中，传感器部件制造在透明基板上，背板背对背连接以产生紧凑的集成结构。

公开(公告)号：US08742406B1

公开(公告)日：2014-06-03

申请号：US13397749

申请日：2012-02-16

申请人： Wai Y. Leung ,  Joong-Mok Park ,  Zhengqing Gan ,  Kristen P. Constant ,  Joseph Shinar ,  Ruth Shinar ,  Kai-Ming Ho

发明人： Wai Y. Leung ,  Joong-Mok Park ,  Zhengqing Gan ,  Kristen P. Constant ,  Joseph Shinar ,  Ruth Shinar ,  Kai-Ming Ho

IPC分类号： H01L51/54

CPC分类号： H01L51/5275 ,  H01L27/14627

摘要： Provided are microlens arrays for use on the substrate of OLEDs to extract more light that is trapped in waveguided modes inside the devices and methods of manufacturing same. Light extraction with microlens arrays is not limited to the light emitting area, but is also efficient in extracting light from the whole microlens patterned area where waveguiding occurs. Large microlens array, compared to the size of the light emitting area, extract more light and result in over 100% enhancement. Such a microlens array is not limited to (O)LEDs of specific emission, configuration, pixel size, or pixel shape. It is suitable for all colors, including white, for microcavity OLEDs, and OLEDs fabricated directly on the (modified) microlens array.

摘要翻译： 提供了用于OLED的衬底上的微透镜阵列，以提取被捕获在器件内的波导模式中的更多光和制造其的方法。 用微透镜阵列进行光提取不限于发光区域，而且也可以在从发生波导的整个微透镜图案区域提取光线方面有效。 大型微透镜阵列，与发光面积相比，提取更多的光，并导致超过100％的增强。 这种微透镜阵列不限于特定发射，配置，像素尺寸或像素形状的（O）LED。 它适用于所有颜色，包括白色，用于微腔OLED，以及直接在（修改的）微透镜阵列上制造的OLED。