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    Implantable marker with wireless signal transmitter
    1.
    发明申请
    Implantable marker with wireless signal transmitter 有权
    带无线信号发射器的可植入标记

    公开(公告)号：US20050154293A1

    公开(公告)日：2005-07-14

    申请号：US10746888

    申请日：2003-12-24

    申请人： Margo Gisselberg ,  Keith Seiler ,  Steven Dimmer

    发明人： Margo Gisselberg ,  Keith Seiler ,  Steven Dimmer

    IPC分类号： A61B5/055 ,  A61B5/06 ,  A61B6/12 ,  A61B19/00 ,  A61N5/10 ,  A61B5/05

    CPC分类号： A61B5/062 ,  A61B5/055 ,  A61B5/06 ,  A61B5/061 ,  A61B5/064 ,  A61B6/12 ,  A61B90/39 ,  A61B2034/2051 ,  A61B2090/3954 ,  A61B2090/3958 ,  A61N2005/1051

    摘要： A wireless marker for localizing a target of a patient comprises a casing and a magnetic transponder at least partially received in the casing. The magnetic transponder produces a wirelessly transmitted magnetic field in response to a wirelessly transmitted excitation energy. The magnetic transponder also has a magnetic centroid. The marker also comprises an imaging element carried by the casing and/or the magnetic transponder. The imaging element has a radiographic profile in a radiographic image such that the marker has a radiographic centroid at least approximately coincident with the magnetic centroid.

    摘要翻译： 用于定位患者目标的无线标记器包括至少部分地容纳在外壳中的壳体和磁性应答器。 磁应答器响应于无线传输的激发能产生无线传输的磁场。 磁转发器也具有磁性质心。 标记还包括由壳体和/或磁性应答器承载的成像元件。 该成像元件具有放射线照相图像中的放射照相轮廓，使得该标记具有至少与磁性质心近似一致的射线照相重心。

    Implantable marker with wireless signal transmitter
    2.
    发明授权
    Implantable marker with wireless signal transmitter 有权
    带无线信号发射器的可植入标记

    公开(公告)号：US08196589B2

    公开(公告)日：2012-06-12

    申请号：US10746888

    申请日：2003-12-24

    申请人： Margo Gisselberg ,  Keith Seiler ,  Steven C. Dimmer

    发明人： Margo Gisselberg ,  Keith Seiler ,  Steven C. Dimmer

    IPC分类号： A61B19/00

    CPC分类号： A61B5/062 ,  A61B5/055 ,  A61B5/06 ,  A61B5/061 ,  A61B5/064 ,  A61B6/12 ,  A61B90/39 ,  A61B2034/2051 ,  A61B2090/3954 ,  A61B2090/3958 ,  A61N2005/1051

    摘要： A wireless marker for localizing a target of a patient comprises a casing and a magnetic transponder at least partially received in the casing. The magnetic transponder produces a wirelessly transmitted magnetic field in response to a wirelessly transmitted excitation energy. The magnetic transponder also has a magnetic centroid. The marker also comprises an imaging element carried by the casing and/or the magnetic transponder. The imaging element has a radiographic profile in a radiographic image such that the marker has a radiographic centroid at least approximately coincident with the magnetic centroid.

    摘要翻译： 用于定位患者目标的无线标记器包括至少部分地容纳在外壳中的壳体和磁性应答器。 磁应答器响应于无线传输的激发能产生无线传输的磁场。 磁转发器也具有磁性质心。 标记还包括由壳体和/或磁性应答器承载的成像元件。 该成像元件具有放射线照相图像中的放射照相轮廓，使得该标记具有至少与磁性质心近似一致的射线照相重心。

    Apparatuses and methods for percutaneously implanting objects in patients
    3.
    发明申请
    Apparatuses and methods for percutaneously implanting objects in patients 审中-公开
    用于经皮植入物体的患者的装置和方法

    公开(公告)号：US20090209804A1

    公开(公告)日：2009-08-20

    申请号：US11658331

    申请日：2005-07-25

    申请人： Keith Seiler ,  Eric Hadford ,  Margo Gisselberg

    发明人： Keith Seiler ,  Eric Hadford ,  Margo Gisselberg

    IPC分类号： A61M36/12 ,  G08B1/08

    CPC分类号： A61M37/0069 ,  A61B17/3468 ,  A61B17/3478 ,  A61B2090/3987 ,  A61N5/1027 ,  A61N2005/1011

    摘要： Apparatuses and methods for percutaneously implanting objects, such as radioactive seeds or markers, in patients. In one embodiment, a device for percutaneously implanting an object in a patient includes a handle, a cannula projecting outwardly from the handle, and an actuator movably disposed relative to the handle. In one aspect of this embodiment, the cannula can be configured to releasably hold the object and percutaneously penetrate the patient. In another aspect of this embodiment, the actuator can be operably connected to the cannula and operable to move the cannula relative to the handle and release the object within the patient. In a further aspect of this embodiment, the cannula can include a tip portion having a restriction configured to releasably hold the object for implantation in the patient.

    摘要翻译： 用于经皮植入物体（如放射性种子或标记物）的患者的装置和方法。 在一个实施例中，用于经皮植入患者物体的装置包括手柄，从手柄向外突出的套管以及相对于手柄可移动地设置的致动器。 在该实施例的一个方面中，插管可被配置为可释放地保持物体并经皮穿透患者。 在该实施例的另一方面，致动器可以可操作地连接到套管并且可操作以相对于手柄移动插管并释放患者体内的物体。 在该实施例的另一方面，套管可以包括具有限制件的末端部分，其被配置为可释放地将物体保持在患者体内。

    Systems and methods for treating a lung of a patient using guided radiation therapy or surgery
    4.
    发明申请
    Systems and methods for treating a lung of a patient using guided radiation therapy or surgery 审中-公开
    使用引导放射治疗或手术治疗患者肺部的系统和方法

    公开(公告)号：US20060093089A1

    公开(公告)日：2006-05-04

    申请号：US11165843

    申请日：2005-06-24

    申请人： Edward Vertatschitsch ,  Steven Dimmer ,  Timothy Mate ,  Eric Meier ,  Keith Seiler ,  J. Wright

    发明人： Edward Vertatschitsch ,  Steven Dimmer ,  Timothy Mate ,  Eric Meier ,  Keith Seiler ,  J. Wright

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1049 ,  A61B34/25 ,  A61B34/30 ,  A61B2034/301 ,  A61B2090/3958 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1051

    摘要： Systems and methods for treating a lung of a patient. One embodiment of a method comprises positioning a leadless marker in the lung of the patient relative to the target, and collecting position data of the marker. This method further comprises determining the location of the marker in an external reference frame outside of the patient based on the collected position data, and providing an objective output in the external reference frame that is responsive to movement of the marker. The objective output is provided at a frequency (i.e., periodicity) that results in a clinically acceptable tracking error. In addition, the objective output can also be provided at least substantially contemporaneously with collecting the position data used to determine the location of the marker.

    摘要翻译： 用于治疗患者肺部的系统和方法。 一种方法的一个实施例包括将无引线标记物相对于靶标定位在患者的肺中，以及收集标记物的位置数据。 该方法还包括基于所收集的位置数据确定标记在患者外部的外部参考框架中的位置，以及响应于标记的移动而在外部参考框架中提供客观输出。 以导致临床上可接受的跟踪误差的频率（即，周期性）提供目标输出。 此外，目标输出还可以至少基本同时提供，收集用于确定标记位置的位置数据。

    Packaged systems for implanting markers in a patient and methods for manufacturing and using such systems
    5.
    发明授权
    Packaged systems for implanting markers in a patient and methods for manufacturing and using such systems 有权
    用于在患者中植入标记的包装系统以及用于制造和使用这种系统的方法

    公开(公告)号：US07407054B2

    公开(公告)日：2008-08-05

    申请号：US11125533

    申请日：2005-05-10

    申请人： Keith Seiler ,  Eric Hadford

    发明人： Keith Seiler ,  Eric Hadford

    IPC分类号： B65D83/10 ,  A61M5/00 ,  A61B17/34

    CPC分类号： A61M37/0069 ,  A61B5/06 ,  A61B50/30 ,  A61B50/3001 ,  A61B50/33 ,  A61B90/39 ,  A61B2090/3975 ,  A61B2090/3987 ,  A61N2005/1011 ,  A61N2005/1051

    摘要： Packaged systems for implanting a marker in a patient and methods for manufacturing and using such systems. In one embodiment, a packaged system comprises an introducer having a cannula and a stylet configured to be received in the cannula, a marker in the cannula, and a package having a sterile compartment. The marker can have a casing configured to be implanted in a patient and a resonating circuit in the casing. The resonating circuit can comprise a coil configured to wirelessly transmit a target signal in response to a wirelessly transmitted excitation signal. The introducer is contained within the sterile compartment. In another embodiment, the marker is not loaded in the introducer within the compartment of the package.

    摘要翻译： 用于在患者中植入标记物的包装系统以及用于制造和使用这种系统的方法。 在一个实施例中，包装系统包括导引器，该导引器具有套管和探针，其被配置为容纳在套管中，套管中的标记物以及具有无菌隔间的包装。 标记物可以具有被配置为植入患者体内的壳体和壳体中的谐振电路。 谐振电路可以包括被配置为响应于无线发送的激励信号而无线地发送目标信号的线圈。 导引器包含在无菌隔间内。 在另一个实施例中，标记物不被装载在包装的隔室内的导入器中。

    Methods for manufacturing packaged systems for implanting markers in a patient
    6.
    发明授权
    Methods for manufacturing packaged systems for implanting markers in a patient 有权
    用于制造用于在患者体内植入标记物的包装系统的方法

    公开(公告)号：US08297030B2

    公开(公告)日：2012-10-30

    申请号：US13196119

    申请日：2011-08-02

    申请人： Keith Seiler ,  Eric Hadford

    发明人： Keith Seiler ,  Eric Hadford

    IPC分类号： B65B5/00 ,  A61B19/00

    CPC分类号： A61M37/0069 ,  A61B5/06 ,  A61B50/30 ,  A61B50/3001 ,  A61B50/33 ,  A61B90/39 ,  A61B2090/3975 ,  A61B2090/3987 ,  A61N2005/1011 ,  A61N2005/1051

    摘要： Packaged systems for implanting a marker in a patient and methods for manufacturing and using such systems. In one embodiment, a packaged system comprises an introducer having a cannula and a stylet configured to be received in the cannula, a marker in the cannula, and a package having a sterile compartment. The marker can have a casing configured to be implanted in a patient and a resonating circuit in the casing. The resonating circuit can comprise a coil configured to wirelessly transmit a target signal in response to a wirelessly transmitted excitation signal. The introducer is contained within the sterile compartment. In another embodiment, the marker is not loaded in the introducer within the compartment of the package.

    摘要翻译： 用于在患者中植入标记物的包装系统以及用于制造和使用这种系统的方法。 在一个实施例中，包装系统包括导引器，该导引器具有套管和探针，其被配置为容纳在套管中，插管中的标记物以及具有无菌隔间的包装。 标记物可以具有被配置为植入患者体内的壳体和壳体中的谐振电路。 谐振电路可以包括被配置为响应于无线发送的激励信号而无线地发送目标信号的线圈。 导引器包含在无菌隔间内。 在另一个实施例中，标记物不被装载在包装的隔室内的导入器中。

    Packaged systems for implanting markers in a patient and methods for manufacturing and using such systems
    7.
    发明授权
    Packaged systems for implanting markers in a patient and methods for manufacturing and using such systems 有权
    用于在患者中植入标记的包装系统以及用于制造和使用这种系统的方法

    公开(公告)号：US06889833B2

    公开(公告)日：2005-05-10

    申请号：US10335067

    申请日：2002-12-30

    申请人： Keith Seiler ,  Eric Hadford

    发明人： Keith Seiler ,  Eric Hadford

    IPC分类号： A61B5/06 ,  A61B19/00 ,  A61B19/02 ,  A61M25/00 ,  A61N5/10 ,  B65D83/10

    CPC分类号： A61M37/0069 ,  A61B5/06 ,  A61B50/30 ,  A61B50/3001 ,  A61B50/33 ,  A61B90/39 ,  A61B2090/3975 ,  A61B2090/3987 ,  A61N2005/1011 ,  A61N2005/1051

    摘要： Packaged systems for implanting a marker in a patient and methods for manufacturing and using such systems. In one embodiment, a packaged system comprises an introducer having a cannula and a stylet configured to be received in the cannula, a marker in the cannula, and a package having a sterile compartment. The marker can have a casing configured to be implanted in a patient and a resonating circuit in the casing. The resonating circuit can comprise a coil configured to wirelessly transmit a target signal in response to a wirelessly transmitted excitation signal. The introducer is contained within the sterile compartment. In another embodiment, the marker is not loaded in the introducer within the compartment of the package.

    摘要翻译： 用于在患者中植入标记物的包装系统以及用于制造和使用这种系统的方法。 在一个实施例中，包装系统包括导引器，该导引器具有套管和探针，其被配置为容纳在套管中，插管中的标记物以及具有无菌隔间的包装。 标记物可以具有被配置为植入患者体内的壳体和壳体中的谐振电路。 谐振电路可以包括被配置为响应于无线发送的激励信号而无线地发送目标信号的线圈。 导引器包含在无菌隔间内。 在另一个实施例中，标记物不被装载在包装的隔室内的导入器中。