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    SYSTEM AND METHOD FOR AUTOMATED BIOPARTICLE RECOGNITION
    1.
    发明申请
    SYSTEM AND METHOD FOR AUTOMATED BIOPARTICLE RECOGNITION 有权
    自动生物识别系统与方法

    公开(公告)号：US20110201511A1

    公开(公告)日：2011-08-18

    申请号：US12667944

    申请日：2008-07-07

    申请人： Mark A. Hayes ,  Thomas J. Taylor ,  Karl Booksh ,  Neal Woodbury ,  Pierre Herckes

    发明人： Mark A. Hayes ,  Thomas J. Taylor ,  Karl Booksh ,  Neal Woodbury ,  Pierre Herckes

    IPC分类号： C40B30/04 ,  C40B60/12 ,  G01N27/447

    CPC分类号： G01N27/44756 ,  B03C5/005 ,  B03C2201/26 ,  G01N21/553 ,  G01N2015/0088

    摘要： The invention relates to a method for identifying the source of shed bioparticles and an apparatus that implements the method. The method involves collecting a sample of bioparticles from the environment, selecting from that sample the bioparticles most effective in identifying their source, and gathering data from those bioparticles to form bioparticle signatures. The bioparticle signatures are then processed into a multi-dimensional vector which is then compared to the multi-dimensional vector derived from a standard using a pattern recognition strategy that identifies the source. The apparatus has a particle collection device to collect the sample, a transfer device that selects information-rich bioparticles and a detector that restricts the movement of the information-rich bioparticles. The restricted movement is then translated into a bioparticle signature.

    摘要翻译： 本发明涉及一种用于鉴定脱落生物颗粒的来源的方法和一种实现该方法的装置。 该方法包括从环境中收集生物颗粒样品，从该样品中选择生物颗粒最有效地鉴定其来源，并从这些生物颗粒收集数据以形成生物颗粒标记。 然后将生物粒子标记处理成多维向量，然后将其与使用识别源的模式识别策略从标准导出的多维向量进行比较。 该装置具有收集样品的颗粒收集装置，选择信息丰富的生物颗粒的转移装置和限制富含信息的生物颗粒的运动的检测器。 受限制的运动然后被转换成生物特征。

    System and method for automated bioparticle recognition
    2.
    发明授权
    System and method for automated bioparticle recognition 有权
    自动生物粒子识别的系统和方法

    公开(公告)号：US08821703B2

    公开(公告)日：2014-09-02

    申请号：US12667944

    申请日：2008-07-07

    申请人： Mark A. Hayes ,  Thomas J. Taylor ,  Karl Booksh ,  Neal Woodbury ,  Pierre Herckes

    发明人： Mark A. Hayes ,  Thomas J. Taylor ,  Karl Booksh ,  Neal Woodbury ,  Pierre Herckes

    IPC分类号： B03C5/02 ,  C40B30/04 ,  C40B60/12

    CPC分类号： G01N27/44756 ,  B03C5/005 ,  B03C2201/26 ,  G01N21/553 ,  G01N2015/0088

    摘要： The invention relates to a method for identifying the source of shed bioparticles and an apparatus that implements the method. The method involves collecting a sample of bioparticles from the environment, selecting from that sample the bioparticles most effective in identifying their source, and gathering data from those bioparticles to form bioparticle signatures. The bioparticle signatures are then processed into a multi-dimensional vector which is then compared to the multi-dimensional vector derived from a standard using a pattern recognition strategy that identifies the source. The apparatus has a particle collection device to collect the sample, a transfer device that selects information-rich bioparticles and a detector that restricts the movement of the information-rich bioparticles. The restricted movement is then translated into a bioparticle signature.

    摘要翻译： 本发明涉及一种用于鉴定脱落生物颗粒的来源的方法和一种实现该方法的装置。 该方法包括从环境中收集生物颗粒样品，从该样品中选择生物颗粒最有效地鉴定其来源，并从这些生物颗粒收集数据以形成生物颗粒标记。 然后将生物粒子标记处理成多维向量，然后将其与使用识别源的模式识别策略从标准导出的多维向量进行比较。 该装置具有收集样品的颗粒收集装置，选择信息丰富的生物颗粒的转移装置和限制富含信息的生物颗粒的运动的检测器。 受限制的运动然后被转换成生物特征。

    SYSTEM AND METHOD FOR AUTOMATED BIOPARTICLE RECOGNITION
    3.
    发明申请
    SYSTEM AND METHOD FOR AUTOMATED BIOPARTICLE RECOGNITION 审中-公开
    自动生物识别系统与方法

    公开(公告)号：US20140371102A1

    公开(公告)日：2014-12-18

    申请号：US14474267

    申请日：2014-09-01

    申请人： Mark A. Hayes ,  Thomas J. Taylor

    发明人： Mark A. Hayes ,  Thomas J. Taylor ,  Karl Booksh ,  Neal Woodbury ,  Pierre Herckes

    IPC分类号： G01N27/447

    CPC分类号： G01N27/44756 ,  B03C5/005 ,  B03C2201/26 ,  G01N21/553 ,  G01N2015/0088

    摘要： Disclosed are embodiments of methods, apparatus, systems, compositions, and articles of manufacture relating to identifying the source of bioparticles, such as bioparticles shed by an organism. In embodiments, a method may include collecting a sample of bioparticles from the environment, selecting from that sample the bioparticles most informative for identifying their source, and gathering data from those bioparticles to form bioparticle signatures; the bioparticle signatures may be processed into a multi-dimensional vector which may be compared to a multi-dimensional vector derived from a standard using a pattern recognition strategy. In embodiments, an apparatus may include a particle collection device to collect a sample, a transfer device to select bioparticles, and a detector that restricts the movement of the bioparticles; the restricted movement may be used to produce a bioparticle signature.

    摘要翻译： 公开了与识别生物颗粒源如生物体脱落的生物颗粒有关的方法，装置，系统，组合物和制品的实施方案。 在实施方案中，方法可以包括从环境中收集生物颗粒的样品，从该样品中选择生物颗粒最有用的资料来识别其来源，以及从这些生物颗粒收集数据以形成生物颗粒标记; 生物粒子标记可以被处理成多维向量，其可以使用模式识别策略与从标准衍生的多维向量进行比较。 在实施例中，装置可以包括用于收集样品的颗粒收集装置，选择生物颗粒的转移装置和限制生物颗粒运动的检测器; 受限运动可用于产生生物粒子标记。

    MICROSTRUCTURE AND MICRODOMAIN MICROARRAYS, METHODS OF MAKING SAME AND USES THEREOF
    10.
    发明申请
    MICROSTRUCTURE AND MICRODOMAIN MICROARRAYS, METHODS OF MAKING SAME AND USES THEREOF 审中-公开
    微结构和微结构微阵列，其制备方法及其用途

    公开(公告)号：US20100056392A1

    公开(公告)日：2010-03-04

    申请号：US11917406

    申请日：2006-06-15

    申请人： Matthew Greving ,  Neal Woodbury ,  Trent R. Northen

    发明人： Matthew Greving ,  Neal Woodbury ,  Trent R. Northen

    IPC分类号： C40B30/10 ,  C40B40/00 ,  C40B50/00 ,  C40B30/00 ,  C40B50/18 ,  C08F118/02

    CPC分类号： G01N33/6851 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00722 ,  B01J2219/00725 ,  G01N33/6845

    摘要： Disclosed are methods for direct characterization of microdomains and/or three-dimensional microstructure arrays bearing high densities of reactive sites using Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometery (MALDI-MS) and other analytical techniques. The high site density of the arrays can provide sufficient sample of each array element and/or materials bound to each element to obtain directly using common analytical techniques such as MALDI-MS. Spatially directed synthesis of heteropolymers is done through the use of pliotolabile, electrically labile, and chemically labile protecting group(s).

    摘要翻译： 公开了使用矩阵辅助激光解吸电离飞行时间质谱（MALDI-MS）和其他分析技术直接表征具有高密度反应位点的微畴和/或三维微结构阵列的方法。 阵列的高位点密度可以提供每个阵列元素和/或与每个元件结合的材料的足够的样品，以直接使用常见的分析技术如MALDI-MS。 异源聚合物的空间定向合成是通过使用不溶性的，电不稳定的和化学上不稳定的保护基进行的。