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    Super plastic design for CHF pacemaker lead
    1.
    发明授权
    Super plastic design for CHF pacemaker lead 失效
    超级塑料设计为CHF起搏器主导

    公开(公告)号：US07403823B1

    公开(公告)日：2008-07-22

    申请号：US11205865

    申请日：2005-08-16

    申请人： Mark W. Kroll ,  John R. Helland ,  Yougandh Chitre ,  Michael Yang

    发明人： Mark W. Kroll ,  John R. Helland ,  Yougandh Chitre ,  Michael Yang

    IPC分类号： A61N1/05

    CPC分类号： A61N1/056 ,  A61N1/0563 ,  A61N2001/0585

    摘要： An implantable lead assembly for a body implantable medical system adapted to transmit electrical signals between a proximal end portion of the lead assembly and a distal end portion of the lead assembly to thereby stimulate selected body tissue includes an elongated insulative sheath of flexible resilient material having at least one longitudinally extending lumen, an electrical conductor received within the lumen of the insulative sheath and extending between a proximal end and a distal end, and at least one elongated super plastic element slidably received within the lumen of the insulative sheath, the super plastic element being bendable to configure the lead assembly to negotiate tortuous turns in the vasculature of the body. An electrical connector is coupled to the proximal end of the conductor for releasable attachment to a stimulating pulse generator and an electrode is coupled to the distal end of the conductor.

    摘要翻译： 一种用于身体可植入医疗系统的可植入引线组件，其适于在引线组件的近端部分和引线组件的远端部分之间传输电信号，从而刺激所选择的身体组织，包括柔性弹性材料的细长绝缘护套， 至少一个纵向延伸的内腔，电导体，其容纳在绝缘护套的内腔内并在近端和远端之间延伸;以及至少一个细长超塑料元件，其可滑动地容纳在绝缘护套的内腔内，超塑料元件 可以弯曲以配置导线组件来协商身体脉管系统中的曲折转弯。 电连接器耦合到导体的近端，用于可释放地附接到刺激脉冲发生器，并且电极耦合到导体的远端。

    Method of manufacturing a drug-eluting endocardial lead utilizing silicone elastomer as a drug carrier
    6.
    发明授权
    Method of manufacturing a drug-eluting endocardial lead utilizing silicone elastomer as a drug carrier 有权
    使用硅氧烷弹性体作为药物载体制造药物洗脱心内膜的方法

    公开(公告)号：US07174221B1

    公开(公告)日：2007-02-06

    申请号：US10736082

    申请日：2003-12-12

    申请人： Cole H. Chen ,  Phong D. Doan ,  Yougandh Chitre ,  John R. Helland

    发明人： Cole H. Chen ,  Phong D. Doan ,  Yougandh Chitre ,  John R. Helland

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0568

    摘要： A drug-eluting endocardial lead and method of manufacture. The silicone elastomer of the present invention is ideally suited to a manufacturing environment due to its extended pot life and decreased curing time. A preferred silicone elastomer is comprised of a multi-part mixture having at least a base portion and a curing portion. Additionally, since curing does not begin until the base and curing portions are combined, the mixing can be physically undertaken closer to the location of the endocardial lead and the curing “clock” does not start until the mixing occurs and external heat is applied. Since the silicone elastomer formed by base and curing components have improved the pot life and curing characteristics, the mixture is suitable for mixing with a steroid and then dispensing into an endocardial lead tip thus eliminating current design limitations imposed by current art while concomitantly minimizing manufacturing costs.

    摘要翻译： 药物洗脱心内膜铅及其制造方法。 本发明的有机硅弹性体由于其使用寿命延长并且固化时间缩短而理想地适用于制造环境。 优选的有机硅弹性体由至少具有基部分和固化部分的多部分混合物组成。 此外，由于固化直到基部和固化部分组合才开始固化，所以混合可以在物理上更接近于心内膜的位置，并且固化“钟”不会开始，直到混合发生并且外部加热。 由于由碱和固化组分形成的硅氧烷弹性体已经改善了适用期和固化特性，所以该混合物适用于与类固醇混合，然后分配到心内膜引导末端，从而消除了当前技术所施加的当前设计限制，同时最小化制造成本 。

    Kink resistant introducer with mapping capabilities
    7.
    发明授权
    Kink resistant introducer with mapping capabilities 失效
    具有映射功能的抗扭结导引器

    公开(公告)号：US07229450B1

    公开(公告)日：2007-06-12

    申请号：US10365270

    申请日：2003-02-11

    申请人： Yougandh Chitre ,  Kevin L. Morgan ,  John R. Helland

    发明人： Yougandh Chitre ,  Kevin L. Morgan ,  John R. Helland

    IPC分类号： A61B5/042

    CPC分类号： A61B5/0422

    摘要： An introducer system for use with a pacemaker lead includes a plastic sheath compatible for insertion within a body, a first end configured for insertion into the body with a second end extending out of the body. A central lumen of the sheath is configured to permit introduction of the lead and includes a flexible, kink-resistant section smooth on its outer surface with a helical pleat defining a helical groove enabling a conductor extending from the mapping probe to the pacing system analyzer to be received in the helical groove of the sheath. A mapping probe at the first end of the sheath is connectable to a pacing system analyzer for seeking a location on the myocardial surface of the heart or an endocardial location at which optimal pacing parameters can be achieved prior to implantation of the lead.

    摘要翻译： 用于与起搏器引线一起使用的导引器系统包括与插入体内相容的塑料护套，第一端被构造成用延伸出身体的第二端插入身体。 护套的中心管被构造成允许引入引线并且在其外表面上包括柔性的抗扭结部分，其中螺旋形褶皱限定了使得能够从映射探针延伸到起搏系统分析器的导体， 被容纳在护套的螺旋槽中。 在鞘的第一端的映射探针可连接到起搏系统分析器，用于寻找心脏心肌表面上的位置或在植入引线之前可以实现最佳起搏参数的心内膜位置。

    Body implantable lead with improved tip electrode assembly
    8.
    发明授权
    Body implantable lead with improved tip electrode assembly 失效
    具有改进的尖端电极组件的主体可植入引线

    公开(公告)号：US06766203B2

    公开(公告)日：2004-07-20

    申请号：US09828353

    申请日：2001-04-05

    申请人： Phong D. Doan ,  John R. Helland ,  Yougandh Chitre

    发明人： Phong D. Doan ,  John R. Helland ,  Yougandh Chitre

    IPC分类号： A61N118

    CPC分类号： A61N1/0565 ,  A61N2001/0578

    摘要： A body implantable lead assembly adapted to transmit electrical tissue stimulating signals between a proximal end portion of the lead assembly and a distal end portion of the lead assembly includes an electrical conductor extending between the proximal and distal end portions of the lead assembly for transmitting the electrical signals. The conductor has an enlarged, preferably ball shaped distal extremity comprising a termination element. The lead assembly includes a tip electrode having a proximal portion, a proximal extremity, a distal portion and a distal extremity, the distal extremity comprising an active electrode surface. At least the proximal portion of the tip electrode comprises a tubular structure, the tubular proximal portion having an inside diameter slightly smaller than the termination element on the distal extremity of the conductor. The tubular proximal portion of the tip electrode has formed within the wall thereof at least one longitudinally oriented, keyhole-shaped opening. The opening comprises an aperture and a longitudinal slot connecting the aperture and the proximal extremity of the tip electrode, the aperture being smaller than the termination element. The termination element is seated in the aperture of the at least one opening and one or welds may be added between the periphery of the aperture and the termination element to enhance the electrical and mechanical integrity of the connection therebetween.

    摘要翻译： 适于在导线组件的近端部分和引线组件的远端部分之间传输电组织刺激信号的主体可植入导线组件包括在导线组件的近端部分和远端部分之间延伸的电导体，用于传导电 信号。 导体具有包括终端元件的放大的，优选球形的远端。 引线组件包括具有近端部分，近端末端，远侧部分和远端末端的尖端电极，远侧末端包括有源电极表面。 至少尖端电极的近端部分包括管状结构，管状近端部分的内径略小于导体的远端上的终端元件。 尖端电极的管状近端部分在其壁内形成有至少一个纵向取向的锁眼形开口。 所述开口包括孔和连接所述孔和所述末端电极的近端的纵向槽，所述孔小于所述端接元件。 终端元件位于至少一个开口的孔中，并且可以在孔的周边和端接元件之间添加一个或焊缝，以增强其间的连接的电气和机械完整性。

    Medical catheter/lead body design and means of manufacture thereof
    9.
    发明授权
    Medical catheter/lead body design and means of manufacture thereof 有权
    医疗导管/引线体设计及其制造方法

    公开(公告)号：US06748277B1

    公开(公告)日：2004-06-08

    申请号：US09977882

    申请日：2001-10-11

    申请人： Yougandh Chitre ,  John R. Helland

    发明人： Yougandh Chitre ,  John R. Helland

    IPC分类号： A61N100

    CPC分类号： A61N1/056

    摘要： An implantable endocardial lead includes a first elongated tubular component of flexible resilient material with a first face and a first longitudinally extending channel forming a partial lumen in the first face, a similar second elongated tubular component with a second face opposite the first face and a second longitudinally extending channel forming a partial lumen in the second face, the first and second tubular components being integrated by contiguously uniting the first and second faces with the first and second partial lumina being in mutually overlying relationship forming a full lumen within the elongated lead body. Elastic or inelastic rings received in longitudinally spaced annular grooves provided in the outer peripheral surface of the elongated lead body bias together the first and second elongated tubular components. An elongated electrical conductor is received in the full lumen and an overlying sheath is in contiguous engagement with the peripheral outer surface.

    摘要翻译： 可植入心内膜包括柔性弹性材料的第一细长管状部件，其具有第一面和形成第一面中的部分内腔的第一纵向延伸通道，具有与第一面相对的第二面的相似的第二细长管状部件， 纵向延伸的通道在第二面中形成部分内腔，第一和第二管状部件通过将第一和第二表面与第一和第二部分腔相接合地结合在一起，所述第一和第二部分光管处于相互重叠的关系中，形成细长引线体内的完整管腔。 容纳在设置在细长引线体的外周表面中的纵向隔开的环形槽中的弹性或非弹性环将第一和第二细长管状部件偏置在一起。 细长电导体被容纳在整个内腔中，并且上覆护套与周边外表面相邻地接合。

    Implantable cardiac lead having terminating connector strain relief and method of manufacture
    10.
    发明授权
    Implantable cardiac lead having terminating connector strain relief and method of manufacture 有权
    具有端接连接器应变消除和制造方法的可植入心脏引线

    公开(公告)号：US06671553B1

    公开(公告)日：2003-12-30

    申请号：US09864542

    申请日：2001-05-23

    申请人： John R. Helland ,  Phong D. Doan ,  Yougandh Chitre

    发明人： John R. Helland ,  Phong D. Doan ,  Yougandh Chitre

    IPC分类号： H61N1372

    CPC分类号： A61N1/056

    摘要： An implantable cardiac lead includes a connector having strain relief to protect the connector from damage during removal of the connector from an associated implantable cardiac stimulation device. The lead is elongated and has a distal end, a proximal end, an electrode, and a conductor coupled to the electrode and extending to the lead proximal end. A connector on the lead proximal end connects the conductor to a mating implantable device connector. The lead connector includes a body, a terminal carried by the body which is coupled to the conductor, an anchor longitudinally fixed on the lead and to the conductor distal to the terminal, and a strain relief member connected between the anchor and the terminal.

    摘要翻译： 可植入心脏引线包括具有应变消除的连接器，以在连接器从相关联的可植入心脏刺激装置移除期间保护连接器免于损坏。 引线是细长的并且具有远端，近端，电极和耦合到电极并延伸到引线近端的导体。 引线近端上的连接器将导体连接到可配合的可植入装置连接器。 引线连接器包括主体，由主体承载的端子，其被连接到导体，纵向固定在引线上的锚固件和远离端子的导体以及连接在锚固件和端子之间的应变消除构件。