公开(公告)号：US07403823B1

公开(公告)日：2008-07-22

申请号：US11205865

申请日：2005-08-16

申请人： Mark W. Kroll ,  John R. Helland ,  Yougandh Chitre ,  Michael Yang

发明人： Mark W. Kroll ,  John R. Helland ,  Yougandh Chitre ,  Michael Yang

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N1/0563 ,  A61N2001/0585

摘要： An implantable lead assembly for a body implantable medical system adapted to transmit electrical signals between a proximal end portion of the lead assembly and a distal end portion of the lead assembly to thereby stimulate selected body tissue includes an elongated insulative sheath of flexible resilient material having at least one longitudinally extending lumen, an electrical conductor received within the lumen of the insulative sheath and extending between a proximal end and a distal end, and at least one elongated super plastic element slidably received within the lumen of the insulative sheath, the super plastic element being bendable to configure the lead assembly to negotiate tortuous turns in the vasculature of the body. An electrical connector is coupled to the proximal end of the conductor for releasable attachment to a stimulating pulse generator and an electrode is coupled to the distal end of the conductor.

摘要翻译： 一种用于身体可植入医疗系统的可植入引线组件，其适于在引线组件的近端部分和引线组件的远端部分之间传输电信号，从而刺激所选择的身体组织，包括柔性弹性材料的细长绝缘护套， 至少一个纵向延伸的内腔，电导体，其容纳在绝缘护套的内腔内并在近端和远端之间延伸;以及至少一个细长超塑料元件，其可滑动地容纳在绝缘护套的内腔内，超塑料元件 可以弯曲以配置导线组件来协商身体脉管系统中的曲折转弯。 电连接器耦合到导体的近端，用于可释放地附接到刺激脉冲发生器，并且电极耦合到导体的远端。

公开(公告)号：US07894915B1

公开(公告)日：2011-02-22

申请号：US11553842

申请日：2006-10-27

申请人： Yougandh Chitre ,  Mark W. Kroll

发明人： Yougandh Chitre ,  Mark W. Kroll

IPC分类号： A61N1/05

CPC分类号： A61N1/372 ,  A61N1/05 ,  A61N1/37205 ,  A61N1/3756

摘要： Techniques related to implantable medical devices (IMDs) are described. One such IMD includes first and second electrodes and a continuous body joined with and extending between the electrodes. Processing electronics are located within the body and are coupled with the first and second electrodes.

摘要翻译： 描述与植入式医疗装置（IMD）相关的技术。 一个这样的IMD包括第一和第二电极以及与电极连接并在电极之间延伸的连续体。 处理电子器件位于主体内并且与第一和第二电极耦合。

公开(公告)号：US08123716B1

公开(公告)日：2012-02-28

申请号：US11768793

申请日：2007-06-26

申请人： Mark W. Kroll ,  Yougandh Chitre

发明人： Mark W. Kroll ,  Yougandh Chitre

IPC分类号： A61M31/00 ,  A61M25/00 ,  A61M37/00 ,  A61N1/30 ,  A61N1/00 ,  A61K9/22

CPC分类号： A61M37/00 ,  A61M37/0015 ,  A61M2205/04 ,  A61M2205/054 ,  A61N1/362 ,  A61N1/3962

摘要： An implantable cardiac therapeutic device having at least one implantable sensor arranged to sense at least one physiologic characteristic of a patient, an implantable therapeutic agent delivery assembly wherein the delivery assembly and a therapeutic agent to be delivered are configured for placement in a patient's pericardial space, and a controller in communication with the at least one implantable sensor and with the therapeutic agent delivery assembly wherein the controller evaluates the at least one physiologic characteristic for indications of a condition indicating administration of the therapeutic agent and wherein, upon detection of such indications, induces the therapeutic agent delivery assembly to deliver the agent. Also an implantable patient lead adapted for connection to a separable implantable therapy device, the lead including an implantable therapeutic agent delivery assembly wherein the delivery assembly and a therapeutic agent to be delivered are configured for placement in a patient's pericardial space.

摘要翻译： 一种植入式心脏治疗装置，其具有布置成感测患者的至少一种生理特征的至少一个可植入传感器，可植入的治疗剂递送组件，其中所述递送组件和待递送的治疗剂被配置用于放置在患者的心包空间中， 以及与所述至少一个可植入传感器和所述治疗剂递送组件通信的控制器，其中所述控制器评估所述至少一个生理特征，用于指示所述治疗剂的施用的状况的指示，并且其中，在检测到所述适应症时，诱导 治疗剂递送组件以递送药剂。 还有一种适于连接到可分离植入式治疗装置的可植入患者导线，所述导线包括可植入治疗剂递送组件，其中所述输送组件和待递送治疗剂被配置用于放置在患者的心包空间中。

公开(公告)号：US07899537B1

公开(公告)日：2011-03-01

申请号：US11553859

申请日：2006-10-27

申请人： Mark W. Kroll ,  Yougandh Chitre

发明人： Mark W. Kroll ,  Yougandh Chitre

IPC分类号： A61N1/39

CPC分类号： A61N1/375 ,  A61B5/0205 ,  A61B5/0422 ,  A61B5/0452 ,  A61N1/025 ,  A61N1/3621 ,  A61N1/3686 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/378 ,  A61N1/3962

摘要： An implantable pericardial device provides therapy to a heart of a patient. In one embodiment electronics, electrodes and other components are provided in a unitary assembly. These components may be implemented such that the unitary assembly has a sufficient degree of flexibility. The implantable pericardial device may be implanted into the pericardial space using a relatively low-invasive technique such as a sub-xiphoid approach.

摘要翻译： 可植入的心包装置为患者的心脏提供治疗。 在一个实施例中，电子器件，电极和其它部件以单一组件提供。 这些组件可以被实现为使得整体组件具有足够的灵活性。 可植入的心包装置可以使用相对低侵入性的技术（例如亚剑突方法）植入心包空间。

公开(公告)号：US06609027B2

公开(公告)日：2003-08-19

申请号：US09793640

申请日：2001-02-23

申请人： Mark W. Kroll ,  John R. Helland

发明人： Mark W. Kroll ,  John R. Helland

IPC分类号： A61N1368

CPC分类号： A61N1/3627 ,  A61N1/368

摘要： A cardiac stimulation device, a His Bundle lead, and an associated method for detecting a conduction signal from the His Bundle. Upon this detection, the stimulation device delivers ventricular stimulation to the right and/or left ventricles at an interval following the atrial depolarization. A sensing window is initiated following the sensing of the atrial depolarization. During the sensing windows, the His Bundle signal received through the His Bundle lead is sampled and a moving average is calculated to determine a signal peak. Detection of the His Bundle signal peak triggers ventricular stimulation, which may be delivered to the right ventricle, the left ventricle, or both ventricles.

摘要翻译： 心脏刺激装置，His束引线，以及用于检测来自His束的传导信号的相关方法。 在这种检测中，刺激装置在心房去极化之后的间隔向右心室和/或左心室递送心室刺激。 在感觉到心房去极化之后启动感测窗口。 在感测窗口期间，通过His Bundle引线接收的His Bundle信号被采样，并计算移动平均线以确定信号峰值。 His Bundle信号峰的检测触发心室刺激，可以将其传送到右心室，左心室或两个脑室。

公开(公告)号：US07010358B1

公开(公告)日：2006-03-07

申请号：US10640242

申请日：2003-08-12

申请人： Mark W. Kroll ,  John R. Helland

发明人： Mark W. Kroll ,  John R. Helland

IPC分类号： A61N1/05

CPC分类号： A61N1/0563

摘要： An implantable cardiac lead for use in the coronary sinus region of a heart for the treatment of congestive heart failure includes an elongated lead body having a plurality of terminals at its proximal end, an electrode assembly including a defibrillation electrode, for example, a metallic coil, and first and second pacing electrodes, the first pacing electrode being an electrode at or adjacent to the tip of the lead spaced from the defibrillation electrode and adjacent the apex of the left ventricle of the heart, the second pacing electrode including a ring electrode spaced proximally from the defibrillation electrode and adjacent the basal region of the left ventricle of the heart, and a plurality of conductors connecting each electrode to a respective one of the terminals at the proximal end of the lead body.

摘要翻译： 用于治疗充血性心力衰竭的心脏冠状窦区域的可植入心脏引线包括：在其近端具有多个端子的细长引线体，包括除颤电极的电极组件，例如金属线圈 以及第一和第二起搏电极，所述第一起搏电极是与所述除颤电极间隔开并且与所述心脏左心室的顶点相邻的所述引线的尖端处或邻近所述引线的电极，所述第二起搏电极包括间隔开的环形电极 从除颤电极向近侧并且靠近心脏左心室的基底区域，以及多个导体，其将每个电极连接到引线主体的近端处的相应的一个端子。

公开(公告)号：US07305270B1

公开(公告)日：2007-12-04

申请号：US11112508

申请日：2005-04-21

申请人： Mark W. Kroll ,  John R. Helland

发明人： Mark W. Kroll ,  John R. Helland

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N1/0573 ,  A61N1/3702 ,  A61N1/3704

摘要： A proximal end of a lead body carries a connector assembly. A first electrical conductor within the lead body electrically connects a tip electrode to a first electrical contact on the connector assembly. A collar electrode is carried by a distal end portion of the lead body. A second electrical conductor within the lead body electrically connects the collar electrode to a second electrical contact on the connector assembly. A ring electrode, carried by the distal end portion of the lead body, is disposed proximally of the collar electrode in spaced-apart relationship thereto and is connected through a switching device to a node point along the first conductor. The switching device has a first state permitting an electrical current to be conducted between the ring electrode and the node point and a second state in which the ring electrode is electrically isolated from the node point. Preferably, the switching device comprises a diode.

摘要翻译： 引线体的近端承载连接器组件。 引线体内的第一电导体将尖端电极与连接器组件上的第一电触点电连接。 凸缘电极由引线体的远端部分承载。 引线体内的第二电导体将接头电极电连接到连接器组件上的第二电触头。 由引线体的远端部分承载的环形电极以与其成间隔开的关系设置在套环电极的近侧，并且通过开关装置连接到沿着第一导体的节点。 开关器件具有允许电流在环形电极和节点之间传导的第一状态和环形电极与节点电气隔离的第二状态。 优选地，开关装置包括二极管。

公开(公告)号：US20130123871A1

公开(公告)日：2013-05-16

申请号：US13735599

申请日：2013-01-07

申请人： Mark W. Kroll

发明人： Mark W. Kroll

IPC分类号： A61N1/39

CPC分类号： A61N1/3937 ,  A61N1/3931 ,  A61N1/3956 ,  A61N2001/083

摘要： Methods and apparatus for accurately and painlessly measuring the impedance between defibrillation electrodes implanted in a patient utilize a high current test pulse delivered with a sufficiently high current to produce an accurate measurement of the defibrillation electrode impedance while limiting the duration of the test pulse such that the pain sensing cells in the patient do not perceive the test pulse. In one embodiment, the test pulse is generated from the high voltage transformer without storing energy in the high voltage capacitors and is delivered to the defibrillation electrodes in the patient utilizing the high voltage switching circuitry.

公开(公告)号：US08340731B2

公开(公告)日：2012-12-25

申请号：US13312023

申请日：2011-12-06

申请人： Braden Kroll ,  Mark W. Kroll

发明人： Braden Kroll ,  Mark W. Kroll

IPC分类号： H04M1/00 ,  H04B1/38

CPC分类号： H04M1/6066 ,  H02J7/025 ,  H02J50/00 ,  H02J50/20 ,  H02J50/40 ,  H04M1/05 ,  H04M2250/02

摘要： A wireless headset has a body, an ear clip, and at least two devices for converting at least two different sources of energy into electrical power. The body includes an RF integrated circuit in electrical communication with an antenna and a baseband circuit, the baseband circuit being in electrical communication with a microphone and a speaker. The at least two devices for converting at least two different sources of energy into electrical power are in electrical communication with the RF integrated circuit and the baseband circuit. The ear clip is engaged to the body. The at least two sources of energy are selected from the group consisting of solar energy, thermoelectric energy, piezoelectric energy, and vibration energy.

摘要翻译： 无线耳机具有主体，耳夹和至少两个用于将至少两个不同的能量源转换成电力的装置。 身体包括与天线和基带电路电通信的RF集成电路，基带电路与麦克风和扬声器电通信。 用于将至少两个不同的能量源转换成电力的至少两个装置与RF集成电路和基带电路电连通。 耳夹与身体接合。 至少两个能量源选自太阳能，热电能，压电能和振动能。

公开(公告)号：US20120255504A1

公开(公告)日：2012-10-11

申请号：US13527073

申请日：2012-06-19

申请人： Mark W. Kroll

发明人： Mark W. Kroll

IPC分类号： A01K29/00

CPC分类号： A01K15/025 ,  A01K15/021

摘要： A phone for pets and pet owners is taught which allows the owner to call the house and “talk” to the pet. The owner can then see a video image of the pet in front of the pet phone to verify presence and happiness. The device can also present the owner's scent to the pet and deliver treats on remote command. In some embodiments, the pet can initiate the phone call.

摘要翻译： 教导宠物和宠物主人的电话，允许业主打电话给房子并与宠物交谈。 然后，所有者可以在宠物电话前看到宠物的视频图像，以验证存在和幸福。 该设备还可以将所有者的香味呈现给宠物，并通过远程命令提供食物。 在一些实施例中，宠物可以启动电话呼叫。