利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

22 条记录 (耗时 0.036 秒)

    EFFICIENT LIGNOCELLULOSE HYDROLYSIS WITH INTEGRATED ENZYME PRODUCTION
    1.
    发明申请
    EFFICIENT LIGNOCELLULOSE HYDROLYSIS WITH INTEGRATED ENZYME PRODUCTION 审中-公开
    具有综合酶生产的高效液体纤维素水解

    公开(公告)号：US20140045227A1

    公开(公告)日：2014-02-13

    申请号：US13977428

    申请日：2012-01-02

    申请人： Markus Rarbach ,  Zdravko Dragovic ,  Andreas Kohl ,  Jochen Gerlach ,  Jörg Bartuch ,  Thomas Brück

    发明人： Markus Rarbach ,  Zdravko Dragovic ,  Andreas Kohl ,  Jochen Gerlach ,  Jörg Bartuch ,  Thomas Brück

    IPC分类号： C12P19/14

    CPC分类号： C12P19/14 ,  C12N9/2434 ,  C12P7/10 ,  Y02E50/16 ,  Y02E50/17

    摘要： The present invention provides a process for degradation of lignocellulosic biomass, which has optionally been pre-treated. It is based on the finding that hydrolysis efficiency of the biomass is enhanced in the presence of a mechanically or chemically treated microorganism capable of producing the respective hydrolytic enzymes. The invention therefore provides a process for degradation of lignocellulosic biomass with integrated produced enzyme cocktails. The invention also provides a process wherein the part of the optionally pre-treated lignocellulosic biomass is incorporated into the final growth medium of the fungus.

    摘要翻译： 本发明提供了一种木质纤维素生物质的降解方法，其中任选地已经预处理过。 基于这样的发现，即在存在能够产生相应的水解酶的机械或化学处理的微生物的情况下，生物质的水解效率得到提高。 因此，本发明提供了一种用综合生产的酶混合物降解木质纤维素生物质的方法。 本发明还提供了一种方法，其中任选预处理的木质纤维素生物质的一部分并入真菌的最终生长培养基中。

    Methods
    8.
    发明申请
    Methods 审中-公开
    方法

    公开(公告)号：US20100216113A1

    公开(公告)日：2010-08-26

    申请号：US12451394

    申请日：2008-05-07

    申请人： Andreas Kohl ,  Said Eshaghi ,  Daniel Martinez Molina ,  Par Nordlund ,  Anders Wetterholm ,  Jesper Z. Haeggstrom

    发明人： Andreas Kohl ,  Said Eshaghi ,  Daniel Martinez Molina ,  Par Nordlund ,  Anders Wetterholm ,  Jesper Z. Haeggstrom

    IPC分类号： C12Q1/00 ,  G06G7/48 ,  C12N9/00

    CPC分类号： C12Q1/25 ,  C07K2299/00 ,  C12N9/1085 ,  C12Y404/0102 ,  G01N33/92 ,  G01N2500/04 ,  G16B15/00

    摘要： A method for selecting or designing a compound expected to modulate the activity of Leukotriene C4 synthase (LTC4S), the method comprising the step of using molecular modelling means to select or design a compound that is predicted to interact with the catalytic site or a substrate binding region of LTC4S, wherein a three-dimensional structure of at least a part of the catalytic site or a substrate binding region of LTC4S is compared with a three-dimensional structure of a compound, and a compound that is predicted to interact with the said catalytic site or substrate binding region is selected. The selected compound may be predicted to bind to at least a part of a region of the structure termed the “GSH substrate binding cavity” (formed by residues including residues Arg51, Arg30, Arg104, Gln53, Asn55, Glu58, Tyr59, Tyr93, Tyr97, Ile27, Pro37, Leu108 of full length human LTC4S, or equivalent residues); the “lipophilic substrate binding crevice” (formed by residues including Ala20, Leu24, Ile27, Tyr59, Trp116, Ala112, Leu115, Leu108, Tyr109, Leu62, Val119, Thr66, Vall6 and Leu17, or equivalent residues); or the “catalytic site” (formed by residues including Arg104 or Arg31, or equivalent residues).

    摘要翻译： 选择或设计预期调节白三烯C4合酶（LTC4S）的活性的化合物的方法，所述方法包括使用分子建模手段来选择或设计预测与催化位点相互作用的化合物或底物结合 LTC4S的区域，其中将LTC4S的至少一部分催化位点或底物结合区域的三维结构与化合物的三维结构进行比较，以及预测与所述催化剂相互作用的化合物 选择位点或底物结合区。 可以预期所选择的化合物可结合称为“GSH底物结合腔”的结构的至少一部分（由残基Arg51，Arg30，Arg104，Gln53，Asn55，Glu58，Tyr59，Tyr93，Tyr97 ，全长人LTC4S的Ile27，Pro37，Leu108或相当的残基）; （由Ala20，Leu24，Ile27，Tyr59，Trp116，Ala112，Leu115，Leu108，Tyr109，Leu62，Val119，Thr66，Vall6和Leu17等残基组成的“亲脂性底物结合缝隙”）。 或“催化位点”（由包含Arg104或Arg31的残基或等同残基形成）。

    Motor Vehicle Brake System Having A Low Pressure Accumulator
    9.
    发明申请
    Motor Vehicle Brake System Having A Low Pressure Accumulator 有权
    具有低压蓄能器的汽车制动系统

    公开(公告)号：US20100045099A1

    公开(公告)日：2010-02-25

    申请号：US12307797

    申请日：2007-07-11

    申请人： Dieter Burkhard ,  Andreas Kohl ,  Jochen Müller ,  Faouzi Attallah

    发明人： Dieter Burkhard ,  Andreas Kohl ,  Jochen Müller ,  Faouzi Attallah

    IPC分类号： B60T8/40

    CPC分类号： B60T8/4059

    摘要： A motor vehicle brake system having a hydraulic cable, via which a wheel brake module can be pressurized by a brake medium using brake pressure from a brake cylinder and to which a low pressure accumulator is connected for temporarily receiving excess brake medium, wherein the low pressure accumulator is connected to the hydraulic cable via a backflow line and a return pump interposed in the return line in order to return temporarily stored brake medium, the return pump being cyclically actuated for adjusting the pump capacity such that an activation occurs within each braking cycle during a portion of pump cycles that corresponds to the pump capacity, is intended to provide particularly high operational safety while also providing a comfortable pedal sensation.

    摘要翻译： 一种具有液压电缆的机动车辆制动系统，通过该液压电缆可以利用来自制动缸的制动压力由制动介质对车轮制动模块进行加压，并且连接有低压蓄能器以临时容纳多余的制动介质，其中低压 蓄能器通过回流管路和回流泵连接到液压电缆，以便返回临时存储的制动介质，回流泵循环地致动以调节泵的容量，使得在每个制动循环期间发生激活 与泵容量相对应的泵循环的一部分旨在提供特别高的操作安全性，同时还提供舒适的踏板感觉。

    Brake pressure control devices
    10.
    发明授权
    Brake pressure control devices 失效
    制动压力控制装置

    公开(公告)号：US6126249A

    公开(公告)日：2000-10-03

    申请号：US117191

    申请日：1999-04-19

    申请人： Andreas Kohl

    发明人： Andreas Kohl

    IPC分类号： B60T8/48 ,  B60T8/40 ,  B60T8/42 ,  B60T13/14 ,  B60T17/00 ,  F04B49/02 ,  B60T13/66

    CPC分类号： F04B49/02 ,  B60T8/404 ,  B60T8/4275 ,  F04B2203/0202 ,  Y10S303/03 ,  Y10S303/11

    摘要： A brake pressure control system is proposed which operates on the fluid-return principle. This system includes a low pressure accumulator which must be emptied upon termination of a braking operation with brake pressure control. In this way, the emptying period is kept as short as possible. To this end, the pump is driven for a defined period. In this emptying period, the motor is controlled by pulse-width modulation, and the electromotive counterforce is measured in the phases of the control signal in which no voltage is applied to the motor. This counterforce is a standard of the rotational speed of the motor or the rotational speed of the connected pump. When the rotational speed or the rotational speed variation exceeds a given value, this can be considered as an indication that the low pressure accumulator is empty. As soon as such a signal appears, the emptying period is terminated by deactivation of the motor.

    摘要翻译： PCT No.PCT / EP97 / 00179 Sec。 371 1999年4月19日第 102（e）1999年4月19日PCT 1997年1月16日PCT PCT。 出版物WO97 / 27093 日期1997年7月31日提出了一种基于流体回流原理运行的制动压力控制系统。 该系统包括低压蓄能器，在制动压力控制结束时必须清空。 这样，排空时间尽可能短。 为此，泵被驱动一段规定的时间。 在这个排空期间，通过脉冲宽度调制来控制电动机，并且在不向电动机施加电压的控制信号的相位中测量电动反作用力。 该反作用力是电动机的转速或连接的泵的转速的标准。 当转速或转速变化超过给定值时，可以将其视为低压蓄能器为空的指示。 一旦出现这种信号，则通过停用电机来终止排空期。