Novel RGS-containing molecules and uses thereof
    1.
    发明申请
    Novel RGS-containing molecules and uses thereof 审中-公开
    新型含RGS的分子及其用途

    公开(公告)号:US20050153414A1

    公开(公告)日:2005-07-14

    申请号:US10989054

    申请日:2004-11-15

    摘要: Novel RGS polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length RGS proteins, the invention further provides isolated RGS fusion proteins, antigenic peptides, and anti-RGS antibodies. The invention also provides RGS nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an RGS gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.

    摘要翻译: 公开了新的RGS多肽,蛋白质和核酸分子。 除了分离的全长RGS蛋白之外,本发明还提供了分离的RGS融合蛋白,抗原肽和抗RGS抗体。 本发明还提供了RGS核酸分子,含有本发明的核酸分子的重组表达载体,已经引入了表达载体的宿主细胞,以及RGS基因导入或破坏的非人类转基因动物。 还提供了利用本发明组合物的诊断,筛选和治疗方法。

    RGS-containing molecules and uses thereof
    2.
    发明授权
    RGS-containing molecules and uses thereof 失效
    含RGS的分子及其用途

    公开(公告)号:US06830914B2

    公开(公告)日:2004-12-14

    申请号:US09894749

    申请日:2001-06-27

    IPC分类号: C12N900

    摘要: Novel RGS polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length RGS proteins, the invention further provides isolated RGS fusion proteins, antigenic peptides, and anti-RGS antibodies. The invention also provides RGS nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an RGS gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.

    摘要翻译: 公开了新的RGS多肽,蛋白质和核酸分子。 除了分离的全长RGS蛋白之外,本发明还提供了分离的RGS融合蛋白,抗原肽和抗RGS抗体。 本发明还提供了RGS核酸分子,含有本发明的核酸分子的重组表达载体,已经引入了表达载体的宿主细胞,以及RGS基因导入或破坏的非人类转基因动物。 还提供了利用本发明组合物的诊断,筛选和治疗方法。

    RGS-containing molecules and uses thereof
    3.
    发明授权
    RGS-containing molecules and uses thereof 失效
    含RGS的分子及其用途

    公开(公告)号:US06274362B1

    公开(公告)日:2001-08-14

    申请号:US09244314

    申请日:1999-02-04

    IPC分类号: C12N916

    摘要: Novel RGS polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length RGS proteins, the invention further provides isolated RGS fusion proteins, antigenic peptides, and anti-RGS antibodies. The invention also provides RGS nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an RGS gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.

    摘要翻译: 公开了新的RGS多肽,蛋白质和核酸分子。 除了分离的全长RGS蛋白之外,本发明还提供了分离的RGS融合蛋白,抗原肽和抗RGS抗体。 本发明还提供了RGS核酸分子,含有本发明的核酸分子的重组表达载体,已经引入了表达载体的宿主细胞,以及RGS基因导入或破坏的非人类转基因动物。 还提供了利用本发明组合物的诊断,筛选和治疗方法。

    Molecules of the AIP-related protein family and uses thereof
    5.
    发明授权
    Molecules of the AIP-related protein family and uses thereof 失效
    AIP相关蛋白家族的分子及其用途

    公开(公告)号:US06326481B1

    公开(公告)日:2001-12-04

    申请号:US09324455

    申请日:1999-06-02

    申请人: David Yowe

    发明人: David Yowe

    IPC分类号: C07K100

    摘要: Novel AIP-6 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length AIP-6 proteins, the invention further provides isolated AIP-6 fusion proteins, antigenic peptides and anti-AIP-6 antibodies. The invention also provides AIP-6 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a AIP-6 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

    摘要翻译: 公开了新型的AIP-6多肽,蛋白质和核酸分子。 除了分离的全长AIP-6蛋白,本发明还提供分离的AIP-6融合蛋白,抗原肽和抗AIP-6抗体。 本发明还提供了AIP-6核酸分子,含有本发明的核酸分子的重组表达载体,已经引入了表达载体的宿主细胞和其中引入了AIP-6基因的非人转基因动物,或 中断了 还提供利用本发明组合物的诊断,筛选和治疗方法。

    RGS-containing molecules and uses thereof
    6.
    发明授权
    RGS-containing molecules and uses thereof 失效
    含RGS的分子及其用途

    公开(公告)号:US06410240B1

    公开(公告)日:2002-06-25

    申请号:US09498959

    申请日:2000-02-04

    IPC分类号: C12Q168

    摘要: Novel RGS polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length RGS proteins, the invention further provides isolated RGS fusion proteins, antigenic peptides, and anti-RGS antibodies. The invention also provides RGS nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an RGS gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.

    摘要翻译: 公开了新的RGS多肽,蛋白质和核酸分子。 除了分离的全长RGS蛋白之外,本发明还提供了分离的RGS融合蛋白,抗原肽和抗RGS抗体。 本发明还提供了RGS核酸分子,含有本发明的核酸分子的重组表达载体,已经引入了表达载体的宿主细胞,以及RGS基因导入或破坏的非人类转基因动物。 还提供了利用本发明组合物的诊断,筛选和治疗方法。