公开(公告)号：US08710192B2

公开(公告)日：2014-04-29

申请号：US12965743

申请日：2010-12-10

申请人： Sarah Rue ,  Steve B. Cohen ,  Jun Li ,  David Yowe

发明人： Sarah Rue ,  Steve B. Cohen ,  Jun Li ,  David Yowe

IPC分类号： C07K16/40 ,  C07K16/00 ,  A61K39/395

CPC分类号： C07K16/40 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92

摘要： The present invention provides antibody antagonists against proprotein convertase subtilisin/kexin type 9a (“PCSK9”) and methods of using such antibodies.

摘要翻译： 本发明提供抗前体蛋白转化酶枯草杆菌蛋白酶/ kexin型9a（“PCSK9”）的抗体拮抗剂和使用这些抗体的方法。

公开(公告)号：USD944666S1

公开(公告)日：2022-03-01

申请号：US29777553

申请日：2021-04-07

申请人： Jun Li

设计人： Jun Li

公开(公告)号：US20200046880A1

公开(公告)日：2020-02-13

申请号：US16656311

申请日：2019-10-17

申请人： Iraklis Kourtis ,  Jun Li ,  Lampros Kourtis

发明人： Iraklis Kourtis ,  Jun Li ,  Lampros Kourtis

IPC分类号： A61L27/34 ,  A61F2/42 ,  A61F2/30 ,  A61F2/44 ,  A61F2/38 ,  A61L27/48 ,  A61L27/18 ,  A61F2/32 ,  A61F2/00 ,  A61F2/40 ,  A61L27/26

摘要： The present disclosure pertains to ionic polymer compositions, including semi- and fully interpenetrating polymer networks, methods of making such ionic polymer compositions, articles made from such ionic polymer compositions, and methods of making such articles and packaging for such articles.

公开(公告)号：US09917301B2

公开(公告)日：2018-03-13

申请号：US14419127

申请日：2012-08-01

申请人： Jun Li ,  Jinhua He ,  Zhenlian Chen ,  Xianhui Zhang ,  Yuanhao Tang ,  Deyu Wang

发明人： Jun Li ,  Jinhua He ,  Zhenlian Chen ,  Xianhui Zhang ,  Yuanhao Tang ,  Deyu Wang

IPC分类号： H01M4/36 ,  H01M4/62 ,  H01M4/485 ,  H01M4/525 ,  H01M4/505 ,  H01M10/0525 ,  H01M4/04 ,  H01M4/131 ,  H01M4/1391 ,  H01M4/58 ,  H01M4/02 ,  H01M10/052

CPC分类号： H01M4/364 ,  H01M4/0471 ,  H01M4/131 ,  H01M4/1391 ,  H01M4/485 ,  H01M4/505 ,  H01M4/525 ,  H01M4/5825 ,  H01M4/622 ,  H01M4/623 ,  H01M4/625 ,  H01M10/052 ,  H01M10/0525 ,  H01M2004/028 ,  Y10T29/49108

摘要： Described herein are solid solution composites that are used as cathode materials for lithium-ion batteries. The solid solution composite of α LiMVO4-βLiNi1-x-yCoxMnyO2, in which LiMVO4 has cubic close-packed structure, LiNi1-x-yCoxMnyO2 has hexagonal layered structure, and both share an oxygen lattice fully or partly. The new solid solution materials have advantage for lithium-ion batteries that the working voltage of the composite is adjustable by controlling the molar ratio of α and β and have higher working voltage than current secondary battery materials.Also described herein are methods of preparing such composite.

公开(公告)号：US09642361B2

公开(公告)日：2017-05-09

申请号：US13642310

申请日：2011-04-15

申请人： Miren Edurne Baroja Fernandez ,  Jun Li ,  Javier Pozueta Romero ,  Ignacio Ezquer Garin ,  Abdellatif Bahaji ,  Francisco Jose Munoz Perez ,  Miroslav Ovecka

发明人： Miren Edurne Baroja Fernandez ,  Jun Li ,  Javier Pozueta Romero ,  Ignacio Ezquer Garin ,  Abdellatif Bahaji ,  Francisco Jose Munoz Perez ,  Miroslav Ovecka

IPC分类号： A01N37/02 ,  A01N63/04 ,  A01N63/02 ,  A01N35/02 ,  C05F11/08 ,  A01N63/00

CPC分类号： A01N37/02 ,  A01N25/00 ,  A01N35/02 ,  A01N63/00 ,  A01N63/02 ,  A01N63/04 ,  A01N2300/00 ,  C05F11/08

摘要： The invention relates to a method for changing the development pattern, increasing the growth and starch accumulation, changing the structure of starch and increasing the resistance to water stress in plants. The method involves culturing plants in an atmosphere containing volatile elements emitted by a microorganism, without there being any physical contact between the microorganism and the plant. The method is based on the discovery that the volatile elements emitted by Gram-positive or Gram-negative bacteria, yeasts and microscopic fungi stimulate an increase in the growth of plants in general, with an increase in the height, the number of leaves and/or the number of branches of the plant, as well as an increase in the accumulated starch and structural change of this biopolymer, and modification of the development pattern, with an increase in floral buds. An increased resistance to water stress can also be observed, in addition to an increase in starch in leaves separated from whole plants.

公开(公告)号：US09438876B2

公开(公告)日：2016-09-06

申请号：US13824344

申请日：2010-09-17

申请人： Jun Li ,  Xiaojun Ma ,  Jun Xu

发明人： Jun Li ,  Xiaojun Ma ,  Jun Xu

IPC分类号： H04N9/80 ,  G11B27/00 ,  G11B27/28 ,  H04N5/783

CPC分类号： H04N9/80 ,  G11B27/005 ,  G11B27/28 ,  H04N5/783

摘要： Trick mode play for controlling video content playback can be realized using a semantic based criterion in order to achieve a more uniform playback experience for the viewer, when that viewer wishes to observe the video content presented according to a selected semantic. In one embodiment of the method, semantics associated with shorter time intervals in the video content are replayed in trick mode play proportionally slower than semantics associated with longer time intervals, wherein the proportionally is determined, at least in part, to the time interval associated with each semantic. In various embodiments, semantics can include scenes, audio, metadata, tags, and the like. The semantics based trick mode play approach allows for a more uniform viewing experience, on a time duration basis, from one semantic to the next.

摘要翻译： 可以使用基于语义的标准来实现用于控制视频内容回放的模式播放，以便当观众希望观察根据所选语义呈现的视频内容时，为观众提供更均匀的播放体验。 在该方法的一个实施例中，与特征模式播放相关联的与视频内容中较短时间间隔相关联的语义比与较长时间间隔相关联的语义成比例地慢，其中，至少部分地至少部分地确定与 每个语义。 在各种实施例中，语义可以包括场景，音频，元数据，标签等。 基于语义的特技模式播放方法允许在时间基础上从一个语义到另一个语义的更均匀的观看体验。

公开(公告)号：US09428568B2

公开(公告)日：2016-08-30

申请号：US13128290

申请日：2009-11-10

申请人： Jun Li ,  Agnès Vignery

发明人： Jun Li ,  Agnès Vignery

IPC分类号： G01N33/53 ,  C07K14/705

CPC分类号： C07K14/705

摘要： Compositions and methods are provided for modulating cell-cell fusion by using agents that modulate expression, activity, or function of intermediate-conductance calcium-activated potassium (SK4) channel. In some embodiments, the compositions and methods of the invention provide for inhibition of multi-nucleated osteoclastogenesis and cell-cell fusion, especially cell fusion involving macrophages. In such embodiments, the compositions can comprise inhibitory nucleic acids, monoclonal antibodies or small molecule inhibitors of the SK4 channels and find use in preventing and/or treating various diseases or disorders including bone loss, autoimmune and inflammatory diseases or disorders, implant and transplant rejection, and cancer metastasis. In other embodiments, the compositions and methods of the invention provide for activation of cell-cell fusion. Also provided are methods to screen for SK4 channel modulators (inhibitors or activators) that modulate cell-cell fusion, particularly macrophage cell fusion.

摘要翻译： 提供了通过使用调节中间电导钙激活钾（SK4）通道的表达，活性或功能的试剂来调节细胞 - 细胞融合的组合物和方法。 在一些实施方案中，本发明的组合物和方法提供了抑制多核破骨细胞发生和细胞 - 细胞融合，特别是涉及巨噬细胞的细胞融合。 在这样的实施方案中，组合物可以包含SK4通道的抑制性核酸，单克隆抗体或小分子抑制剂，并且可用于预防和/或治疗各种疾病或病症，包括骨丢失，自身免疫和炎性疾病或病症，植入物和移植排斥 ，和癌转移。 在其它实施方案中，本发明的组合物和方法提供细胞 - 细胞融合的活化。 还提供了筛选调节细胞融合，特别是巨噬细胞融合的SK4通道调节剂（抑制剂或活化剂）的方法。

公开(公告)号：US09419740B2

公开(公告)日：2016-08-16

申请号：US13289695

申请日：2011-11-04

申请人： Changhoi Koo ,  Jun Li ,  Zhijun Cai

发明人： Changhoi Koo ,  Jun Li ,  Zhijun Cai

IPC分类号： H04W4/00 ,  H04J11/00 ,  H04W88/06 ,  H04W74/00

CPC分类号： H04J11/0023 ,  H04W74/004 ,  H04W88/06

摘要： A method, system and device are provided for avoiding in-device coexistence interference between different radio technologies by allocating random access channel preambles to include one or more dedicated access preambles to be sued for sending IDC interference indication messages over a random access channel (RACH) to a radio access network. In response, the radio network provides control parameters and/or instructions for avoiding interference in a random access response message corresponding to the IDC interference indication message using one or more fields in the MAC subheader and payload fields of a designated IDC MAC PDU message.

摘要翻译： 提供了一种方法，系统和设备，用于通过分配随机接入信道前导码来包括一个或多个专用接入前导码，用于通过随机接入信道（RACH）发送IDC干扰指示消息来避免不同无线电技术之间的设备间共存干扰， 到无线电接入网络。 作为响应，无线电网络提供用于使用指定的IDC MAC PDU消息的MAC子头和有效载荷字段中的一个或多个字段来避免对与IDC干扰指示消息相对应的随机接入响应消息中的干扰的控制参数和/或指令。

公开(公告)号：US09365672B2

公开(公告)日：2016-06-14

申请号：US13990541

申请日：2011-11-29

申请人： Jian Zhou ,  Peng Chen ,  Qun Gu ,  Jun Li ,  Wentao Shi ,  Zongbao Wang ,  Zhiqiang Jiang ,  Xuedong Wu

发明人： Jian Zhou ,  Peng Chen ,  Qun Gu ,  Jun Li ,  Wentao Shi ,  Zongbao Wang ,  Zhiqiang Jiang ,  Xuedong Wu

IPC分类号： C08G63/08 ,  C08G63/60

CPC分类号： C08G63/08 ,  C08G63/60

摘要： A polylactic acid triblock copolymer and a preparation method thereof are described. The polylactic acid triblock copolymer comprises an aromatic polyester oligomer block and a polylactic acid block. The polylactic acid triblock copolymer is obtained by reacting an aromatic polyester oligomer with a monomer lactide at a desired temperature. The polylactic acid block copolymer has a regular structure indicated by peak melting temperatures (Tm) corresponding to the aromatic polyester oligomer block and the polylactic acid block, respectively. Examples of the aromatic polyester oligomer block include polyethylene terephthalate, polybutylene terephthalate, and polyethylene 1,4-naphthalate. Examples of the monomer lactide include L-lactide and D-lactide.

摘要翻译： 描述了聚乳酸三嵌段共聚物及其制备方法。 聚乳酸三嵌段共聚物包含芳族聚酯低聚物嵌段和聚乳酸嵌段。 聚乳酸三嵌段共聚物通过使芳族聚酯低聚物与单体丙交酯在所需温度下反应而获得。 聚乳酸嵌段共聚物具有分别对应于芳族聚酯低聚物嵌段和聚乳酸嵌段的峰值熔融温度（Tm）表示的规则结构。 芳族聚酯低聚物嵌段的实例包括聚对苯二甲酸乙二醇酯， 单体丙交酯的实例包括L-丙交酯和D-丙交酯。

公开(公告)号：US09203559B2

公开(公告)日：2015-12-01

申请号：US13360625

申请日：2012-01-27

申请人： Yiping Wang ,  Jun Li ,  Youn Hyoung Heo

发明人： Yiping Wang ,  Jun Li ,  Youn Hyoung Heo

IPC分类号： H04J3/00 ,  H04L1/18 ,  H04L1/16 ,  H04W72/04 ,  H04J3/16 ,  H04L5/00 ,  H04B7/14 ,  H04J1/10 ,  H04J3/08

CPC分类号： H04W72/1289 ,  H04J3/16 ,  H04L1/1671 ,  H04L1/1854 ,  H04L1/1861 ,  H04L5/001 ,  H04L5/0055 ,  H04L5/1469 ,  H04W72/04

摘要： In some implementations, a method of wireless communications between a wireless communications network and wireless user equipment includes receiving, using a primary Time Division Duplex (TDD) configuration, data on a primary component carrier in a first frequency band. Using a secondary TDD configuration, data on a secondary component carrier is received in a second frequency band different from the first frequency band. A Hybrid Automatic Repeat Request (HARQ) for data received on the secondary component carrier is transmitted using a supplemental TDD configuration. A transmission or retransmission on the secondary component carrier uses a supplemental TDD configuration as well. The supplemental TDD configuration is different from the secondary TDD configuration. Furthermore, an uplink supplemental configuration may be different from a downlink supplemental configuration.

摘要翻译： 在一些实现中，无线通信网络和无线用户设备之间的无线通信的方法包括：使用主时分双工（TDD）配置来接收第一频带中的主分量载波上的数据。 使用辅助TDD配置，在与第一频带不同的第二频带中接收辅助分量载波上的数据。 对辅助分量载波上接收到的数据的混合自动重传请求（HARQ）进行HARQ补充配置。 次要分量载波上的传输或重传也使用补充TDD配置。 辅助TDD配置与辅助TDD配置不同。 此外，上行链路补充配置可以不同于下行链路补充配置。