公开(公告)号：US4634706A

公开(公告)日：1987-01-06

申请号：US664866

申请日：1984-10-25

申请人： Masakatsu Kaneko ,  Misako Kimura ,  Yoshinobu Murofushi ,  Mitsuo Yamazaki ,  Nobuyoshi Iwata ,  Fumio Nakagawa

发明人： Masakatsu Kaneko ,  Misako Kimura ,  Yoshinobu Murofushi ,  Mitsuo Yamazaki ,  Nobuyoshi Iwata ,  Fumio Nakagawa

IPC分类号： C07H19/16 ,  A61K31/70 ,  A61K31/7042 ,  A61K31/7052 ,  A61K31/7076 ,  A61K31/708 ,  A61P5/12 ,  A61P7/02 ,  A61P25/28 ,  A61P35/00 ,  A61P43/00 ,  C07D307/77 ,  C07D405/06 ,  C07D473/00 ,  C07D473/30 ,  C07D493/04 ,  C07H19/02 ,  A61K31/52 ,  C07D473/34 ,  C07D473/38 ,  C07D473/40

CPC分类号： C07H19/02

摘要： Griseolic acid derivatives of formula (I): ##STR1## wherein A represents: ##STR2## have enzyme-inhibitory activity, especially against cAMP PDE and cGMP PDE. When formulated as compositions with appropriate carriers or diluents, they may be used for the treatment of a variety of organic disorders and show toxicities less than griseolic acid itself.

摘要翻译： 式（I）的格列酚酸衍生物：其中A表示：具有酶抑制活性，特别是针对cAMP PDE和cGMP PDE。 当配制成具有适当载体或稀释剂的组合物时，它们可用于治疗各种有机疾病，并且显示低于griseolic acid本身的毒性。

公开(公告)号：US4460765A

公开(公告)日：1984-07-17

申请号：US377435

申请日：1982-05-12

申请人： Atsushi Naito ,  Fumio Nakagawa ,  Takao Okazaki ,  Akira Terahara ,  Seigo Iwado ,  Mitsuo Yamazaki

发明人： Atsushi Naito ,  Fumio Nakagawa ,  Takao Okazaki ,  Akira Terahara ,  Seigo Iwado ,  Mitsuo Yamazaki

IPC分类号： A61K35/74 ,  A61K38/55 ,  A61P9/00 ,  A61P21/02 ,  A61P29/00 ,  A61P35/00 ,  C07G99/00 ,  C07H19/16 ,  C12N9/99 ,  C12P1/06 ,  C12P19/40 ,  C12R1/465 ,  C07H17/02 ,  C12P17/18

CPC分类号： A61K31/70 ,  A61K35/742 ,  C07H19/16 ,  C12N9/99 ,  C12P1/06 ,  C12P19/40 ,  C12R1/465 ,  Y10S435/886

摘要： A new compound, named "Griseolic acid", and its salts and can be prepared by the cultivation of Streptomyces griseoaurantiacus SANK 63479 (FERM-P 5223). Griseolic acid and its salts inhibit the activity of the enzyme cyclic adenosine monophosphate phosphodiesterase and, as a result of this, have variety of physiological activities and uses.

摘要翻译： 一种名为“Griseolic acid”的新化合物及其盐，可以通过培养Griseotoreiacus SANK 63479（FERM-P 5223）来制备。 绿藻酸及其盐抑制环状腺苷磷酸二酯酶的活性，其结果是具有多种生理活性和用途。

公开(公告)号：US4822879A

公开(公告)日：1989-04-18

申请号：US131438

申请日：1987-12-11

申请人： Fumio Nakagawa ,  Yoshio Tsujita ,  Mitsuo Yamazaki

发明人： Fumio Nakagawa ,  Yoshio Tsujita ,  Mitsuo Yamazaki

IPC分类号： C07H19/16 ,  A61K31/70 ,  A61K31/7042 ,  A61K31/7052 ,  A61K31/7076 ,  A61P3/08 ,  A61P9/00 ,  A61P9/08 ,  A61P9/10 ,  A61P11/00 ,  A61P25/02 ,  A61P25/18 ,  A61P25/28 ,  A61P29/00 ,  A61P35/00 ,  A61P43/00 ,  C07H19/02 ,  C12N9/99 ,  C12P19/40 ,  C12R1/465 ,  C07H17/02

CPC分类号： C07H19/02 ,  C12P19/40

摘要： Dihydrodesoxygriseolic acid, which has the formula ##STR1## and salts and esters thereof may be prepared by cultivating a suitable strain of Streptomyces, e.g. Streptomyces griseoaurantiacus No. 43894, and, if necessary, salifying or esterifying the free acid. These compounds inhibit the activity of various cyclic nucleotide phosphodiesterases, particularly cAMP PDE, and, as a result of this, have a variety of physiological activities and uses.

摘要翻译： 具有式（I）的二氢脱氧山梨糖醇酸及其盐和酯可以通过培养合适的链霉菌株，例如， 链霉菌Griseoaurantiacus No. 43894，如果需要，将游离酸成盐或酯化。 这些化合物抑制各种环状核苷酸磷酸二酯酶，特别是cAMP PDE的活性，作为其结果，具有多种生理活性和用途。

公开(公告)号：US5340623A

公开(公告)日：1994-08-23

申请号：US727522

申请日：1991-07-09

申请人： Yoshihiro Menjo ,  Fumio Nakagawa ,  Takuji Nagata ,  Hiroshi Kuriyama

发明人： Yoshihiro Menjo ,  Fumio Nakagawa ,  Takuji Nagata ,  Hiroshi Kuriyama

IPC分类号： B60R13/04 ,  B60R13/00 ,  F21S8/10

CPC分类号： B60R13/00 ,  Y10T428/24628 ,  Y10T428/24736 ,  Y10T428/24752 ,  Y10T428/24942

摘要： An ornamental panel for automobiles has a synthetic resin cover. An attaching base is molded separately from the cover and disposed opposite a rear surface of the cover. The cover is molded of a translucent material. The cover has its outer surface made smooth and its inner surface formed with a fine rugged pattern such as crimps. The base has a surface with a rugged pattern of a dimension larger than a dimension of the crimps of the cover. The pattern of the base may be hemispheric concave fisheyes which are two-dimensionally arranged side by side, for example. A metallic film is coated on the pattern of the base.

摘要翻译： 用于汽车的装饰板具有合成树脂盖。 安装底座与盖分开模制，并且与盖的后表面相对地设置。 盖由半透明材料模制。 盖子的外表面光滑，其内表面形成一个细小的凹凸图案，如卷边。 底座具有表面，该表面具有尺寸大于盖的卷曲尺寸的尺寸的凹凸图案。 基底的图案可以是例如二维排列的半球形凹形鱼眼。 金属膜涂覆在基底的图案上。

公开(公告)号：US20100222372A1

公开(公告)日：2010-09-02

申请号：US12682599

申请日：2008-10-10

申请人： Kazuki Sakamoto ,  Fumio Nakagawa

发明人： Kazuki Sakamoto ,  Fumio Nakagawa

IPC分类号： A61K31/505 ,  C07D239/46 ,  C07D403/06 ,  A61P1/00

CPC分类号： A61K31/513

摘要： To provide a therapeutic agent for inflammatory bowel disease.The therapeutic agent for inflammatory bowel disease contains, as an active ingredient, a uracil derivative or a pharmaceutically acceptable salt thereof, represented by formula (1).

摘要翻译： 提供炎症性肠病的治疗剂。 炎症性肠病治疗剂含有式（1）所示的尿嘧啶衍生物或其药学上可接受的盐作为活性成分。

公开(公告)号：US4421362A

公开(公告)日：1983-12-20

申请号：US316276

申请日：1981-10-29

申请人： Kenji Shirai ,  Fumio Nakagawa

发明人： Kenji Shirai ,  Fumio Nakagawa

IPC分类号： B60T8/46 ,  B60T8/26 ,  B60T8/34 ,  B60T8/02

CPC分类号： B60T8/344 ,  B60T8/266

摘要： In an anti-skid brake control system incorporated with dual hydraulic braking circuits for independently controlling respective braking fluids supplied to the right and left rear-wheel brake cylinders from a tandem master cylinder, an electronic anti-skid brake control apparatus is incorporated with one of the hydraulic braking circuits for decreasing the pressure applied to one of the rear-wheel brake cylinders from the master cylinder in response to an electric signal indicative of a predetermined wheel locking condition, and a modulator valve assembly is incorporated with the other hydraulic braking circuit to cooperate with the anti-skid brake control apparatus so as to control the pressure applied to the other rear-wheel brake cylinder in response to activation of the anti-skid brake control apparatus.

摘要翻译： 在具有双重液压制动回路的防滑制动控制系统中，用于独立地控制从串联主缸向左右后轮制动缸提供的各个制动液，将电子防滑制动控制装置与 用于响应于表示预定的车轮锁定状态的电信号而降低从主汽缸向一个后轮制动缸施加的压力的液压制动回路和调节阀组件与另一个液压制动回路结合 与防滑制动控制装置配合，以响应于防滑制动控制装置的启动而控制施加到另一后轮制动缸的压力。

公开(公告)号：US4343892A

公开(公告)日：1982-08-10

申请号：US148608

申请日：1980-05-12

申请人： Kazushige Uenaka ,  Shinichi Kashiwagi ,  Toshiro Tahara ,  Kazuo Shirasu ,  Yoshio Usui ,  Akira Abe ,  Fumio Nakagawa ,  Tetsuya Masuda

发明人： Kazushige Uenaka ,  Shinichi Kashiwagi ,  Toshiro Tahara ,  Kazuo Shirasu ,  Yoshio Usui ,  Akira Abe ,  Fumio Nakagawa ,  Tetsuya Masuda

IPC分类号： G03C5/38 ,  C22B11/00 ,  G03C5/00 ,  G03D3/06 ,  G03D13/00 ,  G03C5/26

CPC分类号： G03D3/065

摘要： The efficiency of silver recovery from photographic processing solutions is improved by the installation of a silver recovery water tank between the fix or blix tank and the wash water tank, which is provided with a mechanism for maintaining the silver concentration of said recovery tank at a substantially constant value, said mechanism comprising a detecting means for measuring the amount of the photographic material treated by the processing line involved and a means to supply water thereto operatable by signal from said detecting means.

摘要翻译： 通过在固定或混合罐与洗涤水箱之间安装银回收水箱来提高从照相处理溶液中回收银的效率，其中设置有用于将所述回收罐的银浓度保持在基本上 所述机构包括用于测量由所述处理线处理的照相材料的量的检测装置，以及可由来自所述检测装置的信号供应水的装置。

公开(公告)号：US4880282A

公开(公告)日：1989-11-14

申请号：US344480

申请日：1989-04-12

申请人： Nobuhiko Makino ,  Kimio Tamura ,  Hiroharu Miyazaki ,  Tomohiko Hosoda ,  Fumio Nakagawa

发明人： Nobuhiko Makino ,  Kimio Tamura ,  Hiroharu Miyazaki ,  Tomohiko Hosoda ,  Fumio Nakagawa

IPC分类号： B60T17/00 ,  B60T8/175 ,  B60T8/40 ,  B60T8/44 ,  B60T8/48 ,  B60T13/14 ,  B60T17/02 ,  B60T17/18

CPC分类号： B60T8/489 ,  B60T13/148 ,  B60T8/175 ,  B60T8/4045 ,  B60T8/44 ,  B60T8/4809 ,  B60T2270/203 ,  Y10S303/03 ,  Y10S303/04

摘要： A braking system of a motor vehicle including an accumulator, being coupled to a to motor-driven pump, for accumulating a hydraulic pressure which is supplied to a braking device to brake a wheel of the motor vehicle and a control valve provided between the accumulator and the braking device for regulating the hydraulic pressure to be applied from the accumulator to the braking device. Also included in the braking system is a control unit for controlling the control valve in accordance with the condition of the wheel. The control unit controls the motor-driven pump on the basis of the control time of the control valve.

公开(公告)号：US4690638A

公开(公告)日：1987-09-01

申请号：US892012

申请日：1986-08-01

申请人： Fumio Nakagawa ,  Kazuyoshi Nakamura ,  Hitoshi Shibao ,  Hiroshi Yoshimura ,  Koichi Taki ,  Makoto Inoue ,  Eiji Hayashi ,  Fusao Dejima ,  Yuritoshi Kohara

发明人： Fumio Nakagawa ,  Kazuyoshi Nakamura ,  Hitoshi Shibao ,  Hiroshi Yoshimura ,  Koichi Taki ,  Makoto Inoue ,  Eiji Hayashi ,  Fusao Dejima ,  Yuritoshi Kohara

IPC分类号： C21C5/52 ,  F27D3/00 ,  F27D3/06 ,  F27D9/00 ,  F27D13/00 ,  F27D15/02

CPC分类号： F27D13/002 ,  C21C5/527 ,  F27D3/06 ,  F27D2009/0013 ,  F27D3/0028 ,  Y02P10/216 ,  Y10S266/901

摘要： A bucket cooled by circulating water and scrap preheating apparatus incorporating the bucket are disclosed. The bucket comprises a bucket-shaped container which contains scrap to be preheated and through which an exhaust gas from an electric furnace is passed to preheat the scrap contained therein, a cooling water passageway which surrounds the periphery of said container, and water supply and exhaust ports which are connected to said cooling water passageway, cooling water being supplied to and exhausted from the bucket during preheating of the scrap contained therein.

摘要翻译： 公开了一种通过循环水和装有铲斗的废料预热装置冷却的水桶。 铲斗包括一个桶形容器，其中包含待预热的废料，并且来自电炉的废气通过该桶形容器预热其中所含的废料，围绕所述容器周围的冷却水通道，以及供水和排气 连接到所述冷却水通道的端口，在预热包含在其中的废料时，冷却水被供应到和从桶中排出。

公开(公告)号：US4624508A

公开(公告)日：1986-11-25

申请号：US637719

申请日：1984-08-06

申请人： Yoshiharu Adachi ,  Asao Kozakai ,  Shingo Watanabe ,  Nobuyasu Nakanishi ,  Hiroyuki Oka ,  Fumio Nakagawa

发明人： Yoshiharu Adachi ,  Asao Kozakai ,  Shingo Watanabe ,  Nobuyasu Nakanishi ,  Hiroyuki Oka ,  Fumio Nakagawa

IPC分类号： B60T8/32 ,  B60T8/34 ,  B60T8/40 ,  B60T8/42 ,  B62D5/07 ,  B60T8/02

CPC分类号： B60T8/341 ,  B60T8/328 ,  B60T8/4054 ,  B60T8/4225

摘要： A regulator valve for a hydraulic anti-skid apparatus and which includes a housing provided with a first inlet port for connection to a fluid pump and the anti-skid apparatus, a second inlet port for connection to a master cylinder, and an outlet port for connection to a fluid reservoir, a regulator piston reciprocably disposed within the housing to form a first fluid chamber in open communication with the first inlet and outlet ports and a second fluid chamber in open communication with the second inlet port, and a spring loaded annular valve seat member arranged within the first fluid chamber to cooperate with a valve part of the piston so as to control the fluid flow from the first inlet port to the outlet port in response to the difference in pressure between the fluid chambers. A support member is arranged within the first fluid chamber formed therein with an axial bore in which a large diameter portion of the piston is slidably disposed to form a third annular fluid chamber. The support member is further formed with an orifice for effecting the fluid flow between the first and third fluid chambers in response to axial movement of the piston.

摘要翻译： 一种用于液压防滑装置的调节阀，其包括壳体，其具有用于连接到流体泵的第一入口端口和防滑装置，用于连接到主缸的第二入口端口和用于 连接到流体储存器，调节器活塞可往复地设置在壳体内以形成与第一入口和出口开口连通的第一流体室和与第二入口端开口连通的第二流体室，以及弹簧加载的环形阀 座部件布置在第一流体室内以与活塞的阀部分配合，以响应于流体室之间的压力差来控制从第一入口到出口的流体流动。 支撑构件布置在其中形成有第一流体室中的轴向孔中，活塞的大直径部分可滑动地布置在其中，以形成第三环形流体室。 支撑构件还形成有孔，用于响应于活塞的轴向运动而实现第一和第三流体室之间的流体流动。