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    Method for manufacturing alpha-glycosylisoquercitrin, intermediate product and by-product thereof
    1.
    发明申请
    Method for manufacturing alpha-glycosylisoquercitrin, intermediate product and by-product thereof 有权
    制备α-糖基异槲皮素的方法，其中间产物及其副产物

    公开(公告)号：US20080187622A1

    公开(公告)日：2008-08-07

    申请号：US10740607

    申请日：2003-12-22

    申请人： Masamitsu Moriwaki ,  Kazuhiro Emura ,  Hisashi Tanaka

    发明人： Masamitsu Moriwaki ,  Kazuhiro Emura ,  Hisashi Tanaka

    IPC分类号： C11B5/00

    CPC分类号： C12P19/60 ,  A23L5/41 ,  A23L33/105 ,  A61K31/352 ,  A61K31/7048 ,  C12P17/06

    摘要： The present invention provides a method for producing isoquercitrin, α-glycosylisoquercitrin, and rhamnose, the method comprising a step of naringin-degrading enzyme treatment during the isoquercitrin production from rutin in the presence of an edible component, such as gelatin, wheat gluten, chitosan, lecithin, a glycerol fatty acid ester, xanthan gum, carrageenan, sodium chondroitin sulfate, casein, enzymatically decomposed gelatin, sodium alginate, konjac extract, gellan gum, guar gum, soybean protein, agar, pectin, yeast extract, egg-white peptide, cluster dextrin, gum arabic, arginine, sodium metaphosphate, karaya gum, locust bean gum, sodium pyrophosphate, glucosamine, chitin, sodium glutamate, dextrin, trehalose, or a grain-based food ingredients. According to the present invention, isoquercitrin and α-glycosylisoquercitrin, which are of use as antioxidants, anti-fading agents, flavor change inhibitors, etc., can be produced in enhanced yields.

    摘要翻译： 本发明提供异槲皮素，α-糖基异槲皮苷和鼠李糖的制备方法，该方法包括在可食用成分如明胶，小麦面筋，壳聚糖存在下，从芦丁生产异槲皮苷期间柚苷降解酶处理的步骤 ，卵磷脂，甘油脂肪酸酯，黄原胶，角叉菜胶，硫酸软骨素钠，酪蛋白，酶分解明胶，藻酸钠，魔芋提取物，结冷胶，瓜尔胶，大豆蛋白，琼脂，果胶，酵母提取物，蛋白肽 ，糊精，阿拉伯树胶，精氨酸，偏磷酸钠，刺槐豆胶，刺槐豆胶，焦磷酸钠，葡糖胺，甲壳素，谷氨酸钠，糊精，海藻糖或谷物类食品成分。 根据本发明，可以以增加的产率制备用作抗氧化剂的异槲皮素和α-糖基异槲皮素，抗褪色剂，风味变化抑制剂等。

    Method for manufacturing α-glycosylisoquercitrin, intermediate product and by-product thereof
    2.
    发明授权
    Method for manufacturing α-glycosylisoquercitrin, intermediate product and by-product thereof 有权
    α-糖基异槲皮素的制备方法，其中间产物及其副产物

    公开(公告)号：US07691425B2

    公开(公告)日：2010-04-06

    申请号：US10740607

    申请日：2003-12-22

    申请人： Masamitsu Moriwaki ,  Kazuhiro Emura ,  Hisashi Tanaka

    发明人： Masamitsu Moriwaki ,  Kazuhiro Emura ,  Hisashi Tanaka

    IPC分类号： A23L1/00

    CPC分类号： C12P19/60 ,  A23L5/41 ,  A23L33/105 ,  A61K31/352 ,  A61K31/7048 ,  C12P17/06

    摘要： The present invention provides a method for producing isoquercitrin, α-glycosylisoquercitrin, and rhamnose, the method comprising a step of naringin-degrading enzyme treatment during the isoquercitrin production from rutin in the presence of an edible component, such as gelatin, wheat gluten, chitosan, lecithin, a glycerol fatty acid ester, xanthan gum, carrageenan, sodium chondroitin sulfate, casein, enzymatically decomposed gelatin, sodium alginate, konjac extract, gellan gum, guar gum, soybean protein, agar, pectin, yeast extract, egg-white peptide, cluster dextrin, gum arabic, arginine, sodium metaphosphate, karaya gum, locust bean gum, sodium pyrophosphate, glucosamine, chitin, sodium glutamate, dextrin, trehalose, or a grain-based food ingredients. According to the present invention, isoquercitrin and α-glycosylisoquercitrin, which are of use as antioxidants, anti-fading agents, flavor change inhibitors, etc., can be produced in enhanced yields.

    摘要翻译： 本发明提供异槲皮素，α-糖基异槲皮素和鼠李糖的制造方法，其特征在于，在可食用成分如明胶，小麦面筋，壳聚糖等存在下，由芦丁生产异槲皮素期间柚皮苷降解酶处理步骤 ，卵磷脂，甘油脂肪酸酯，黄原胶，角叉菜胶，硫酸软骨素钠，酪蛋白，酶分解明胶，藻酸钠，魔芋提取物，结冷胶，瓜尔胶，大豆蛋白，琼脂，果胶，酵母提取物，蛋白肽 ，糊精，阿拉伯树胶，精氨酸，偏磷酸钠，刺槐豆胶，刺槐豆胶，焦磷酸钠，葡糖胺，甲壳素，谷氨酸钠，糊精，海藻糖或谷物类食品成分。 根据本发明，可以以增加的产率生产用作抗氧化剂的异槲皮素和α-糖基异槲皮素，抗褪色剂，风味变化抑制剂等。

    Quercetin Glycoside Composition and Method of Preparing the Same
    4.
    发明申请
    Quercetin Glycoside Composition and Method of Preparing the Same 审中-公开
    槲皮素糖苷组合物及其制备方法

    公开(公告)号：US20090143317A1

    公开(公告)日：2009-06-04

    申请号：US11794218

    申请日：2005-12-28

    申请人： Yoshiko Ono ,  Namino Tomimori ,  Norifumi Tateishi ,  Masamitsu Moriwaki ,  Kazuhiro Emura ,  Shuji Okuyama

    发明人： Yoshiko Ono ,  Namino Tomimori ,  Norifumi Tateishi ,  Masamitsu Moriwaki ,  Kazuhiro Emura ,  Shuji Okuyama

    IPC分类号： A61K31/7048 ,  C12P19/60

    CPC分类号： C12P19/22 ,  A23L3/3463 ,  A23L3/3562 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/7048 ,  C12P19/60 ,  A61K2300/00 ,  A23V2200/02 ,  A23V2250/21168

    摘要： The present invention provides an α-glycosyl isoquercitrin-containing novel composition which has a high in vivo absorbability, and hence exhibits a significant in vivo antioxidative activity. The present invention further provides preparation methods for such a composition. The composition contains a mixture of quercetin glycosides represented by the following formula: wherein Glc represents a glucose residue, and n is 0 or a positive integer of 1 or more,includes at least a quercetin glycoside wherein n is 3, and satisfies the following requirement (a):(a) the total proportion of quercetin glycosides in which n is 3, and in which other n values may be 1 or 2, or 1 and 2, is 50 mol % or more, and the total proportion of quercetin glycosides wherein n is 4 or more is 15 mol % or less, in the composition. The composition can be prepared by treating an enzymatically modified isoquercitrin with β-amylase.

    摘要翻译： 本发明提供了具有高体内吸收性的α-糖基异槲皮苷新化合物，因此具有显着的体内抗氧化活性。 本发明还提供了这种组合物的制备方法。 该组合物含有由下式表示的槲皮素糖苷的混合物：其中，Glc表示葡萄糖残基，n为0或1以上的正整数，至少包含槲皮素苷，n为3，满足以下要求 （a）：（a）其中n为3，其它n值可以为1或2，或1和2的槲皮素苷的总比例为50摩尔％以上，槲皮素苷的总比例 n为4以上15摩尔％以下。 可以通过用β-淀粉酶处理酶促修饰的异槲皮素来制备组合物。

    Method for suppressing fading of tar colorant, and fading-suppressed tar colorant-containing composition
    5.
    发明申请
    Method for suppressing fading of tar colorant, and fading-suppressed tar colorant-containing composition 审中-公开
    用于抑制焦油着色剂褪色的方法和含有褪色抑制焦油着色剂的组合物

    公开(公告)号：US20060051472A1

    公开(公告)日：2006-03-09

    申请号：US11123048

    申请日：2005-05-06

    申请人： Takatoshi Koda ,  Masamitsu Moriwaki ,  Hisashi Tanaka ,  Kouji Utida

    发明人： Takatoshi Koda ,  Masamitsu Moriwaki ,  Hisashi Tanaka ,  Kouji Utida

    IPC分类号： A23B7/157

    CPC分类号： A23L3/26 ,  A23L3/3463 ,  A23L3/3472

    摘要： The present invention provides a method of suppressing fading of a tar colorant. More specifically, the present invention provides a method of suppressing a tar colorant fading phenomenon that occurs specifically in compositions containing (a) the tar colorant, and (b) at least one of reducing sugars, ascorbic acid compounds, or metals. This method can be attained by mixing (c) at least one selected from the group consisting of isoquercitrin, enzymatically modified isoquercitrin, rutin, enzymatically modified rutin, Chinese bayberry extract, and rosemary extract into such a composition, thus making the component (a), the component (b) and the component (c) coexist. The present invention further provides a composition for which fading of a tar colorant is suppressed using the above method, more specifically a composition containing at least one of reducing sugars, ascorbic acid compounds, or metals in addition to the tar colorant.

    摘要翻译： 本发明提供抑制焦油着色剂褪色的方法。 更具体地说，本发明提供一种抑制在含有（a）焦油着色剂的组合物中具体发生的焦油着色剂褪色现象的方法，和（b）还原糖，抗坏血酸化合物或金属中的至少一种。 该方法可以通过将（c）选自异槲皮素，酶促改性的异槲皮苷，芦丁，酶促改性芦丁，中国杨梅提取物和迷迭香提取物中的至少一种混合到这样的组合物中，从而使组分（a） ，组分（b）和组分（c）共存。 本发明还提供一种组合物，其中使用上述方法抑制焦油着色剂的褪色，更具体地说，除了焦油着色剂之外还包含含有还原糖，抗坏血酸化合物或金属中的至少一种的组合物。

    Method of manufacturing sugars by trehalase
    6.
    发明授权
    Method of manufacturing sugars by trehalase 失效
    通过海藻糖酶制造糖的方法

    公开(公告)号：US5593869A

    公开(公告)日：1997-01-14

    申请号：US474703

    申请日：1995-06-07

    申请人： Sumio Kitahata ,  Hirofumi Nakano ,  Tsutomu Washino ,  Masamitsu Moriwaki

    发明人： Sumio Kitahata ,  Hirofumi Nakano ,  Tsutomu Washino ,  Masamitsu Moriwaki

    IPC分类号： C12N1/12 ,  C12N9/24 ,  C12P19/12 ,  C12R1/89

    CPC分类号： C12P19/12 ,  C12N9/2402 ,  C12Y302/01028 ,  Y10S435/946

    摘要： Novel trehalase having the properties that it hydrolyzes .alpha.,.alpha.'-trehalose, 2,2'-dideoxy-.alpha.,.alpha.'-trehalose and 2-deoxy-.alpha.,.alpha.'-trehalose into the respective constituting sugars while it does not act on neotrehalose, lactose, maltose, celobiose and sucrose; its optimum pH is 5 to 6; its optimum temperature is 65.degree. C.; it is stable against heating up to 65.degree. C.; its molecular weight as measured by a gel filtration is 400,000 to 500,000 while the molecular weight of the subunit as measured by a sodium dodecylsulfate--polyacrylamide gel electrophoresis is 180,000 to 250,000; its isoelectric point as measured by an isoelectricfocusing is 2.7; and it is a glycoprotein.

    摘要翻译： 具有将α，α'-海藻糖，2,2'-二脱氧-α，α'-海藻糖和2-脱氧-α，α'-海藻糖水解成各自组成糖的性质的新型海藻糖酶，同时不起作用 新海藻糖，乳糖，麦芽糖，头孢噻吩和蔗糖; 其最适pH为5〜6; 其最适温度为65℃。 对于加热至65℃是稳定的; 其通过凝胶过滤测量的分子量为40万至500,000，而通过十二烷基硫酸钠 - 聚丙烯酰胺凝胶电泳测量的亚基的分子量为18万至25万; 通过等电聚焦测量的等电点为2.7; 它是糖蛋白。