利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

62 条记录 (耗时 0.026 秒)

    Polyhydroxycarboxylic acid and preparation process thereof
    4.
    发明授权
    Polyhydroxycarboxylic acid and preparation process thereof 失效
    聚羟基羧酸及其制备方法

    公开(公告)号：US5310865A

    公开(公告)日：1994-05-10

    申请号：US992696

    申请日：1992-12-18

    申请人： Katashi Enomoto ,  Masanobu Ajioka ,  Akihiro Yamaguchi

    发明人： Katashi Enomoto ,  Masanobu Ajioka ,  Akihiro Yamaguchi

    IPC分类号： C08G63/06

    CPC分类号： C08G63/06

    摘要： A process for preparing polyhydroxycarboxylic acid by conducting a dehydration condensation of a hydroxycarboxylic acid or an oligomer thereof in a reaction mixture containing an organic solvent substantially in the absence of water and the polyhydroxycarboxylic acid thus obtained. The process provides polyhydroxycarboxylic acid having excellent properties and processability.

    摘要翻译： 通过在含有基本上不存在水的有机溶剂和由此得到的聚羟基羧酸的反应混合物中进行羟基羧酸或其低聚物的脱水缩合制备聚羟基羧酸的方法。 该方法提供具有优异性能和加工性能的聚羟基羧酸。

    Preparation process of .alpha.-aspartyl-L-phenylalanine methyl ester
    7.
    发明授权
    Preparation process of .alpha.-aspartyl-L-phenylalanine methyl ester 失效
    α-天门冬酰基-L-苯丙氨酸甲酯的制备方法

    公开(公告)号：US5424477A

    公开(公告)日：1995-06-13

    申请号：US128739

    申请日：1993-09-30

    申请人： Chojiro Higuchi ,  Ikumi Kitada ,  Akinori Nagatomo ,  Katashi Enomoto ,  Masanobu Ajioka ,  Akihiro Yamaguchi

    发明人： Chojiro Higuchi ,  Ikumi Kitada ,  Akinori Nagatomo ,  Katashi Enomoto ,  Masanobu Ajioka ,  Akihiro Yamaguchi

    IPC分类号： A23L27/30 ,  C07K5/075 ,  C07C209/06

    CPC分类号： C07K5/0613

    摘要： .alpha.-L-Aspartyl-L-phenylalanine methyl ester (.alpha.-APM) is prepared by catalytic hydrogenation of N-benzyloxycarbonyl-.alpha.-L-aspartyl-L-phenylalanine methyl ester (Z-.alpha.-APM). The catalytic hydrogenation is conducted in an aqueous suspension containing the Z-.alpha.-APM in the form of particles whose average particle size is not greater than 800 .mu.m. The starting Z-.alpha.-APM may contain up to 30 wt. % of its .beta.-isomer provided that the process additionally includes recrystallization of the .alpha.-APM, collection of the .alpha.-APM by filtration and recycling of the filtrate for use in the aqueous suspension of Z-.alpha.-APM.

    摘要翻译： 通过N-苄氧羰基-α-L-天冬氨酰-L-苯丙氨酸甲酯（Z-α-APM）的催化氢化制备α-L-天冬氨酰-L-苯丙氨酸甲酯（α-APM）。 催化氢化在含有平均粒径不大于800μm的颗粒形式的Z-α-APM的水性悬浮液中进行。 起始的Z-α-APM可含有至多30wt。 ％的β-异构体，条件是该方法另外包括α-APM的重结晶，通过过滤收集α-APM并再循环用于Z-α-APM的水悬浮液中的滤液。

    Degradable monofilament and preparation process thereof
    8.
    发明授权
    Degradable monofilament and preparation process thereof 失效
    可降解单丝及其制备方法

    公开(公告)号：US6090910A

    公开(公告)日：2000-07-18

    申请号：US984538

    申请日：1997-12-03

    申请人： Hosei Shinoda ,  Masanobu Ajioka

    发明人： Hosei Shinoda ,  Masanobu Ajioka

    IPC分类号： A61L17/12 ,  D01F6/84 ,  C08G63/08 ,  A61L17/00 ,  C08G63/88 ,  D02J1/22

    CPC分类号： D01F6/84 ,  A61L17/12

    摘要： A degradable copolymer filament comprising an internal structure having the following separate phases: (a) a matrix phase comprised as a primary component of a polymer segment which exhibits a tensile Young's modulus of 2 GPa or less and a strength retention of 50% or more after two weeks in water at 37.degree. C., pH 7.3, and (b) a micro-dispersed phase comprised as a primary component of a polymer segment which exhibits a tensile strength of 200 MPa or more and a strength reduction greater than the matrix phase in water at 37.degree. C., pH 7.3. The weight ratio of each component in the matrix phase and dispersed phase is 50:50 to 95:5, respectively, and the dispersed phase a needle structure oriented by stretching in the fiber direction. A degradable monofilament having an excellent mechanical strength and flexibility, moderate hydrolyzability, high ligature stability and being suitable as a material of surgical absorbable suture can be obtained. A preparation process is also provided.

    摘要翻译： 一种可降解共聚物长丝，其包含具有以下分离相的内部结构：（a）基质相，其包含作为聚合物链段的主要组分，其显示出2GPa或更小的拉伸杨氏模量和50％以上的强度保持率 在37℃，pH7.3的水中两周，和（b）包含作为聚合物链段的主要组分的微分散相，其表现出200MPa或更大的拉伸强度，并且强度降低大于基体相 在37℃，pH 7.3的水中。 基体相和分散相中各成分的重量比分别为50:50〜95:5，分散相为沿纤维方向拉伸取向的针状结构。 可以获得具有优异的机械强度和柔韧性，适度的水解性，高韧带稳定性并且适合作为手术可吸收缝合材料的可降解单丝。 还提供了一个准备过程。

    Bioabsorbable polymer and process for preparing the same
    9.
    发明授权
    Bioabsorbable polymer and process for preparing the same 失效
    生物可吸收聚合物及其制备方法

    公开(公告)号：US5747637A

    公开(公告)日：1998-05-05

    申请号：US697571

    申请日：1996-08-28

    申请人： Hosei Shinoda ,  Masanobu Ajioka ,  Kimitaka Chida

    发明人： Hosei Shinoda ,  Masanobu Ajioka ,  Kimitaka Chida

    IPC分类号： A61L17/12 ,  C08G63/08

    CPC分类号： C08G63/08 ,  A61L17/12

    摘要： A bioabsorbable, ternary block copolymer consisting essentially of (A) polylactic acid segment, (B) poly(.epsilon.-caprolactone) segment and (C) polyglycolic acid segment, preparation process of the block copolymer, and medical molded articles prepared from said block copolymer. The bioabsorbable block copolymer is excellent in mechanical strength and flexibility and has moderate hydrolyzability and is especially utilized for a surgical monofilament suture.

    摘要翻译： 主要由（A）聚乳酸链段，（B）聚（ε-己内酯）链段和（C）聚乙醇酸链段组成的生物可吸收的三元嵌段共聚物，嵌段共聚物的制备方法和由所述嵌段共聚物 。 生物可吸收嵌段共聚物的机械强度和柔韧性优异，具有适度的水解性，特别适用于手术单丝缝合。