公开(公告)号：US5247013A

公开(公告)日：1993-09-21

申请号：US902794

申请日：1992-06-26

申请人： Hosei Shinoda ,  Masami Ohtaguro ,  Shigeru Iimuro

发明人： Hosei Shinoda ,  Masami Ohtaguro ,  Shigeru Iimuro

IPC分类号： C08G63/06 ,  C08G63/664

CPC分类号： C08G63/664 ,  C08G63/06

摘要： A biocompatible polyester which has improved hydrolyzability obtained by bonding saccharide to the structure of a polymer consisting of a glycolic acid unit and/or a lactic acid unit, and a process for Preparing the biocompatible polyester are disclosed.

摘要翻译： 公开了具有改善的水解性的生物相容性聚酯，其通过将糖键合到由乙醇酸单元和/或乳酸单元组成的聚合物的结构上而获得，并且制备生物相容性聚酯的方法。

公开(公告)号：US5223546A

公开(公告)日：1993-06-29

申请号：US870336

申请日：1992-04-17

申请人： Kenji Morita ,  Kohichi Uchiki ,  Hosei Shinoda

发明人： Kenji Morita ,  Kohichi Uchiki ,  Hosei Shinoda

IPC分类号： B29C44/56 ,  C08J9/06 ,  C08J9/12

CPC分类号： B29C44/5672 ,  B29C44/5627 ,  C08J9/06 ,  C08J9/103 ,  C08J9/12 ,  C08J2367/04

摘要： A degradable polymer network obtained by adding from 0.2 to 10 parts by weight of a foaming agent to 100 parts by weight of a polylactic acid-base resin composition comprising from 80 to 100% by weight of polylactic acid or a lactic acid-hydroxycarboxylic acid copolymer and from 0 to 20% by weight of a plasticizer, conducting melt-foaming extrusion of resulting mixture, and opening the foam cells in the extrudate. The high polymer network is characterized in suitable flexibility and hydrolyzability and thus useful as a material for absorbing oils and body fluids, screens for sunlight, heat-insulating materials, filter media and packaging materials; and does not accumulate as industrial wastes because of hydrolyzability in the natural environment, even though abandoned after use.

公开(公告)号：US4859763A

公开(公告)日：1989-08-22

申请号：US216371

申请日：1988-07-08

申请人： Hiroshi Takayanagi ,  Tadashi Kobayashi ,  Takayoshi Masuda ,  Hosei Shinoda

发明人： Hiroshi Takayanagi ,  Tadashi Kobayashi ,  Takayoshi Masuda ,  Hosei Shinoda

IPC分类号： C08G63/06 ,  A61K9/20 ,  A61K9/22 ,  C08G63/08 ,  C08G63/78 ,  C08G63/82 ,  C08G63/85

CPC分类号： A61K9/204 ,  C08G63/08 ,  C08G63/823

摘要： A process for copolymerizing lactide and glycolide by using a specific amount of stannous octoate as a catalyst in the presence of a polymerization regulator at temperature of 200.degree.-230.degree. C. to prepare dl-lactic acid-glycolic acid-copolymers which contain 50-60 mol % of a dl-lactic acid unit and 40-50 mol % of a glycolic acid unit and have inherent viscosity of 0.4-0.6 in chloroform.

公开(公告)号：US20070160861A1

公开(公告)日：2007-07-12

申请号：US10589431

申请日：2005-02-09

申请人： Hosei Shinoda ,  Takeshi Kashima ,  Masahiro Enna ,  Shinichi Kojoh ,  Hideyuki Kaneko ,  Shingo Matsuo ,  Nobuo Kawahara ,  Tomoaki Matsugi ,  Yuichi Matsuda ,  Takayuki Onogi ,  Fumio Kageyama

发明人： Hosei Shinoda ,  Takeshi Kashima ,  Masahiro Enna ,  Shinichi Kojoh ,  Hideyuki Kaneko ,  Shingo Matsuo ,  Nobuo Kawahara ,  Tomoaki Matsugi ,  Yuichi Matsuda ,  Takayuki Onogi ,  Fumio Kageyama

IPC分类号： B32B27/30

CPC分类号： C08L51/06 ,  C08L23/00 ,  C08L23/02 ,  C08L67/02 ,  C08L69/00 ,  Y10T428/31786 ,  Y10T428/31855 ,  Y10T428/31935 ,  Y10T428/31938 ,  C08L2666/24 ,  C08L2666/18 ,  C08L2666/14 ,  C08L2666/02

摘要： A modified polyolefin resin comprising a copolymer having a structure that a propylene-based polyolefin segment (a) and a segment (b) containing a lactic acid as a constituent are bonded in a block state and/or a graft state through a vinyl monomer having a hydroxyl group, wherein a number average molecular weight of the propylene-based polyolefin segment (a) is from 1,000 to 100,000, a number average molecular weight of the segment (b) containing lactic acid as a constituent is from 1,000 to 200,000, and a weight composition of the propylene-based polyolefin segment (a) and the segment (b) containing lactic acid as a constituent is from 10/90 to 90/10. The modified polyolefin resin can be used in a resin composition containing an aliphatic polyester resin (A), a polyolefin resin (B) and the modified polyolefin resin (C). The composition can exhibit excellent heat resistance and impact resistance and can be used for molding various parts.

摘要翻译： 包含具有丙烯类聚烯烃链段（a）和含有乳酸作为组分的链段（b）的结构的共聚物的改性聚烯烃树脂以嵌段状态和/或接枝状态通过具有 羟基，其中丙烯类聚烯烃链段（a）的数均分子量为1,000〜100,000，以乳酸为成分的链段（b）的数均分子量为1,000〜200,000，以及 丙烯类聚烯烃链段（a）和含有乳酸作为成分的链段（b）的重量组成为10/90〜90/10。 改性聚烯烃树脂可用于含有脂族聚酯树脂（A），聚烯烃树脂（B）和改性聚烯烃树脂（C）的树脂组合物中。 该组合物可以表现出优异的耐热性和抗冲击性，并且可用于各种部件的成型。

公开(公告)号：US06372880B1

公开(公告)日：2002-04-16

申请号：US09219452

申请日：1998-12-23

申请人： Hosei Shinoda ,  Yukiko Asou ,  Hiroaki Tamatani

发明人： Hosei Shinoda ,  Yukiko Asou ,  Hiroaki Tamatani

IPC分类号： C08G6344

CPC分类号： C08G73/1092 ,  A61K9/1641 ,  C08G73/16

摘要： A copolymer having a weight-average molecular weight of 1,000 to 100,000 which comprises, as repeating structure units, both of a succinimide unit represented by the structural formula (1) and a hydroxycarboxylic acid unit represented by the structural formula (2) wherein R is a methyl group or a hydrogen atom, and a process for preparing a copolymer which comprises a polymerization step of heating a mixture of aspartic acid and a cyclic ester compound.

摘要翻译： 一种重均分子量为1,000〜100,000的共聚物，其包含由结构式（1）表示的琥珀酰亚胺单元和由结构式（2）表示的羟基羧酸单元作为重复结构单元，其中R为 甲基或氢原子，以及制备共聚物的方法，其包括加热天冬氨酸和环状酯化合物的混合物的聚合步骤。

公开(公告)号：US06342241B1

公开(公告)日：2002-01-29

申请号：US09488707

申请日：2000-01-21

申请人： Yukiko Asou ,  Hosei Shinoda ,  Hiroaki Tamatani

发明人： Yukiko Asou ,  Hosei Shinoda ,  Hiroaki Tamatani

IPC分类号： A61F1300

CPC分类号： A61K47/34 ,  A61K9/0024

摘要： A medical composition is here disclosed which comprises a hydroxy acid-based oligomer (A) and a drug (B), wherein the hydroxy acid-based oligomer (A) is an oligomer in which the carboxylic acid-terminals are at least partially esterified, and the oligomer (A) has a function of becoming pH 5 to 8 when administered into an organism, and the oligomer (A) shows fluidity at 25° C. This composition sustainedly releases the drug (B) to deliver it into an organism by a syringe or the like, and scarcely gives rise to irritation, inflammation or the like.

摘要翻译： 这里公开了包含羟基酸类低聚物（A）和药物（B）的医药组合物，其中羟基酸类低聚物（A）是其中羧酸末端至少部分酯化的低聚物， 并且低聚物（A）在施用于生物体时具有变为pH5〜8的功能，低聚物（A）在25℃下显示出流动性。该组合物持续释放药物（B），以通过 注射器等，几乎不引起刺激，炎症等。

公开(公告)号：US5437918A

公开(公告)日：1995-08-01

申请号：US145621

申请日：1993-11-04

申请人： Keiko Taniguchi ,  Masahiro Washino ,  Shinobu Moriya ,  Hosei Shinoda ,  Masami Ohtaguro ,  Akihiro Funae ,  Shigeru Iimuro

发明人： Keiko Taniguchi ,  Masahiro Washino ,  Shinobu Moriya ,  Hosei Shinoda ,  Masami Ohtaguro ,  Akihiro Funae ,  Shigeru Iimuro

IPC分类号： C08G63/08 ,  D04H1/42 ,  D04H3/02 ,  D04H3/14 ,  B32B1/02 ,  B32B1/08 ,  B32B1/10 ,  B32B27/02

CPC分类号： D04H3/02 ,  C08G63/08 ,  D04H1/435 ,  D04H1/4382 ,  D04H3/14 ,  Y10T428/31786 ,  Y10T442/697

摘要： A degradable non-woven fabric obtained from an web formed of lactic acid-based polymer filaments comprising of one or more lactic acid-based polymers selected from a poly (DL-lactic acid) having more than 80 mol % of L-lactic acid units, poly (DL-lactic acid) having more than 80 mol % of D-lactic acid units, L-lactic acid/hydroxycarboxylic acid copolymer having 70 mol % or more of L-lactic acid units, and D-lactic acid/hydroxycarboxylic acid copolymer having 70 mol % or more of D-lactic acid units, and a preparation process of the degradable non-woven fabric which has good dimensional stability and can be degraded and disappeared under natural environment when abandoned.

摘要翻译： 从由乳酸类聚合物长丝形成的纤维网得到的可降解无纺布，其包含一种或多种乳酸基聚合物，所述乳酸基聚合物选自具有大于80mol％的L-乳酸单元的聚（DL-乳酸） ，D-乳酸单元多于80摩尔％的聚（DL-乳酸），L-乳酸单元70摩尔％以上的L-乳酸/羟基羧酸共聚物，D-乳酸/羟基羧酸 具有70摩尔％以上的D-乳酸单元的共聚物和可降解无纺布的制备方法，其具有良好的尺寸稳定性，并且在废弃时可以在自然环境下降解和消失。

公开(公告)号：US5434004A

公开(公告)日：1995-07-18

申请号：US338791

申请日：1994-11-08

申请人： Masanobu Ajioka ,  Katashi Enomoto ,  Akihiro Yamaguchi ,  Hosei Shinoda

发明人： Masanobu Ajioka ,  Katashi Enomoto ,  Akihiro Yamaguchi ,  Hosei Shinoda

IPC分类号： B32B27/06 ,  B32B3/10 ,  A61K31/74 ,  B32B3/26

CPC分类号： B32B27/06 ,  Y10S428/913 ,  Y10T428/2969 ,  Y10T428/31504 ,  Y10T428/31993 ,  Y10T442/3854

摘要： A laminate comprising a thermoplastic polymer essentially consisting of polylactic acid, a copolymer of lactic acid and hydroxycarboxylic acid or a mixture of polylactic acid with a copolymer of lactic acid and hydroxycarboxylic acid, and a regenerated cellulose film, paper, leather, cloth, or fiber. The laminate undergoes degradability in the natural environment, is excellent in transparency, gloss and moisture-proofness, has high strength and can be used for various packaging materials.

摘要翻译： 包含基本由聚乳酸，乳酸和羟基羧酸的共聚物或聚乳酸与乳酸和羟基羧酸的共聚物的混合物的热塑性聚合物和再生纤维素膜，纸，皮革，布或纤维组成的层压体 。 层压体在自然环境中经历降解性，透明性，光泽和防湿性优异，强度高，可用于各种包装材料。

公开(公告)号：US5340646A

公开(公告)日：1994-08-23

申请号：US871651

申请日：1992-04-21

申请人： Kenji Morita ,  Kohichi Uchiki ,  Hosei Shinoda

发明人： Kenji Morita ,  Kohichi Uchiki ,  Hosei Shinoda

IPC分类号： C08J5/18 ,  B32B3/06 ,  C08G63/08

CPC分类号： C08J5/18 ,  C08J2367/04 ,  Y10S428/91 ,  Y10T428/249956 ,  Y10T428/25 ,  Y10T428/258

摘要： A breathable, hydrolyzable, porous film which is obtained by the process comprising adding from 40 to 250 parts by weight of a finely-powdered filler having an average particle size of from 0.3 to 4 .mu.m to 100 parts by weight of a polylactic acid-based resin composition comprising from 80 to 100% by weight of polylactic acid or a lactic acid-hydroxycarboxylic acid copolymer and from 0 to 20% by weight of a plasticizer, melting and film-forming the resultant mixture, and successively stretching the thus-obtained film 1.1 times or more at least in the direction of the axis; and which is consequently useful as a material for leakproof films of sanitary materials such as a paper diaper and packaging materials, and does not accumulate as wastes because of hydrolyzability in the natural environment in the case of being abandoned after use.

摘要翻译： 一种透气的，可水解的多孔膜，其通过该方法获得，包括将40至250重量份的平均粒度为0.3至4μm的细粉末填料加入到100重量份的聚乳酸 - 包含80-100重量％的聚乳酸或乳酸 - 羟基羧酸共聚物和0-20重量％的增塑剂，熔融和成膜所得混合物，并依次拉伸由此获得的 至少在轴的方向上为1.1倍以上的膜; 因此可用作纸尿布和包装材料等卫生材料的防漏膜的材料，并且由于在使用后放弃的情况下由于自然环境中的水解性而不会作为废物积聚。

公开(公告)号：US06372844B1

公开(公告)日：2002-04-16

申请号：US09536677

申请日：2000-03-28

申请人： Hosei Shinoda ,  Yukiko Asou ,  Hiroaki Tamatani

发明人： Hosei Shinoda ,  Yukiko Asou ,  Hiroaki Tamatani

IPC分类号： C08L5108

CPC分类号： C08L67/02 ,  C08L69/00 ,  C08L101/00 ,  C08L2666/20

摘要： There are here disclosed a resin composition comprising a block or a graft copolymer (A) having a polyamino acid as a hydrophilic segment (a-1), and a degradable polymer as a hydrophobic segment (a-2), and a resin (B); and a method of accelerating the hydrolysis of a resin and inhibiting the heat deterioration thereof by mixing this copolymer (A) with the resin (B).

摘要翻译： 这里公开了包含具有聚氨基酸作为亲水性链段（a-1）的嵌段或接枝共聚物（A）和作为疏水链段（a-2）的可降解聚合物和树脂（B）的树脂组合物 ）; 和通过将该共聚物（A）与树脂（B）混合来加速树脂的水解并抑制其热劣化的方法。