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公开(公告)号：US09283327B2
公开(公告)日：2016-03-15
申请号：US13993531
申请日：2011-12-21
CPC分类号： A61M5/3245 , A61M5/2033 , A61M5/326 , A61M2005/206 , A61M2005/208
摘要： According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe; a syringe retainer slidably arranged with respect to the housing that mounts a pre-filled syringe with an injection needle, a plunger and a stopper for sealing a syringe barrel of the pre-filled syringe; a coupling shroud slidably arranged within the housing and releasably coupled to the plunger; and a single drive means. Upon release, the single drive means is capable of driving the coupling shroud in the proximal direction (P). The proximal translatory movement of the coupling shroud with respect to the housing, translates the syringe retainer in the proximal direction (P) to expose the injection needle of the pre-filled syringe, depresses the plunger connected to the stopper into the syringe barrel to expel the dose of medicament (M) and advances a needle shroud to a safe position (PS) to surround the injection needle after the medicament (M) has been at least partially delivered. The coupling shroud is decoupled from the plunger at a pre-determined second position (II) defined by an aperture formed into the housing.
摘要翻译： 根据本发明，用于给药液体药物（M）的自动注射器包括布置成容纳预填充注射器的基本上圆柱形的壳体; 相对于所述壳体可滑动地布置的注射器保持器，其用注射针，柱塞和用于密封所述预先填充的注射器的注射器筒的止动器安装预填充的注射器; 联接罩，其可滑动地布置在所述壳体内并且可释放地联接到所述柱塞; 和单个驱动装置。 在释放时，单个驱动装置能够沿近端方向（P）驱动联接罩。 耦合护罩相对于壳体的近侧平移运动使注射器保持器沿近端方向（P）平移以暴露预填充注射器的注射针，将连接到塞子的柱塞压入注射器筒以排出 药剂（M）的剂量并且在药物（M）已经被至少部分递送之后，将针罩延伸到安全位置（PS）以包围注射针。 耦合罩在由形成在壳体中的孔限定的预定的第二位置（II）处与柱塞分离。
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公开(公告)号：US08911410B2
公开(公告)日：2014-12-16
申请号：US13579450
申请日：2011-02-16
CPC分类号： A61M5/3221 , A61M5/2033 , A61M5/3204 , A61M5/326 , A61M2005/206 , A61M2005/2073
摘要： The invention relates to an auto-injector (1) with a delay mechanism (36) for slowing down motion of a retraction sleeve (10) in axial direction of the auto-injector (1), the delay mechanism (36) comprising a circumferential outer wall (37) with a back collar (38) attached to a housing (2) of the auto-injector (1) and a circumferential inner wall (39) with a front collar (40) attached to the retraction sleeve (10) wherein a cavity is defined between the outer wall (37) and inner wall (39), the cavity sealed by the back collar (38) against the inner wall (39) and by the front collar (40) against the outer wall (37), the cavity filled with a viscous fluid, wherein at least one orifice is arranged in the delay mechanism (36) for allowing the viscous fluid to be pushed out as the volume of the cavity decreases due to axial motion of the component with respect to the housing. The retraction sleeve (10) is axially movably arranged in the housing (2) and serves for retracting the syringe (3) with the needle (4) into the covered position after delivering the medicament (M).
摘要翻译： 本发明涉及一种具有延迟机构（36）的自动注射器（1），用于在自动注射器（1）的轴向方向上减慢收缩套筒（10）的运动，延迟机构（36）包括周向 外壁（37），其具有附接到自动注射器（1）的壳体（2）的后环（38）和具有附接到缩回套筒（10）的前轴环（40）的周向内壁（39） 其中在所述外壁（37）和所述内壁（39）之间限定空腔，所述空腔被所述后环（38）密封抵靠所述内壁（39），并且所述前轴环（40）抵靠所述外壁（37） ），所述空腔填充有粘性流体，其中在所述延迟机构（36）中布置有至少一个孔口，用于当所述部件的轴向运动相对于所述腔体的轴向运动减小时，允许粘性流体被推出 住房。 缩回套筒（10）可轴向移动地布置在壳体（2）中，用于在输送药物（M）之后将注射器（3）用针（4）缩回到覆盖位置。
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公开(公告)号：US09724472B2
公开(公告)日：2017-08-08
申请号：US13993528
申请日：2011-12-21
CPC分类号： A61M5/2033 , A61M5/326 , A61M5/50 , A61M2005/206 , A61M2005/208
摘要： According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud slibably arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).
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4.发明授权Autoinjector having piston rod with non-circular axial bore slidably arranged on housing shaft to prevent relative rotation 有权自动注射器具有活动杆，其具有非圆形轴向孔，可滑动地布置在壳体轴上以防止相对旋转公开(公告)号：US09572937B2
公开(公告)日：2017-02-21
申请号：US13579339
申请日：2011-02-16
CPC分类号： A61M5/20 , A61M5/326 , A61M5/46 , A61M2005/206 , A61M2005/208 , A61M2005/3247 , A61M2205/581
摘要： The invention relates to a clutch mechanism for the transmission of a rotary movement from a gear arrangement comprising a first gear member and a second gear member. The first gear member is rotatable about a longitudinal axis but axially fixed wherein the first gear member, upon rotation, is arranged for translatively moving a second gear member which is prevented from rotating. The clutch mechanism comprises a circumferential shoulder arranged at the second gear member and at least one or a number of resilient clutch fingers with respective inclined inner surfaces arranged at the first gear member, the shoulder arranged for increasingly pressing against the inclined surfaces thereby flexing the clutch fingers outward when the shoulder reaches the clutch fingers in the course of its translation. The clutch mechanism further comprises tube arranged around the clutch fingers, the tube having a number of internal longitudinal splines for engaging the flexed-out clutch fingers.
摘要翻译： 本发明涉及一种用于从包括第一齿轮构件和第二齿轮构件的齿轮装置传递旋转运动的离合器机构。 第一齿轮构件可围绕纵向轴线旋转但是轴向固定，其中第一齿轮构件在旋转时被布置成平移地移动阻止旋转的第二齿轮构件。 离合器机构包括布置在第二齿轮构件处的周向肩部和至少一个或多个弹性离合器指状物，其具有布置在第一齿轮构件处的相应的倾斜内表面，肩部设置成越来越多地压靠倾斜表面，从而使离合器 当肩膀在其翻译过程中到达离合器手指时，手指向外。 离合器机构还包括围绕离合器指状物布置的管，管具有用于接合弯曲离合器指的多个内部纵向花键。
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公开(公告)号：US09248245B2
公开(公告)日：2016-02-02
申请号：US13579435
申请日：2011-02-16
CPC分类号： A61M5/2033 , A61M5/3204 , A61M5/3232 , A61M5/326 , A61M2005/206 , A61M2005/2073
摘要： An auto-injector for administering a dose of a liquid medicament comprising an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), operating the syringe to supply the dose of medicament (M), and retracing the syringe with the needle into the covered position. After delivering the medicament, an activator arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection.
摘要翻译： 一种用于给药剂量的自动注射器，所述自动注射器包括细长壳体，所述细长壳体布置成容纳具有中空针头的注射器和用于密封所述注射器并使所述药剂移位的止动件，所述壳体具有远端和近端， 旨在应用于注射部位。 注射器相对于壳体可滑动地布置。 一种弹簧，其能够在激活时将所述针从所述壳体内的覆盖位置推入所述孔的前进位置并经过所述近端（P），操作所述注射器以供应所述剂量的药物（M），并且使所述针 注射器与针头进入覆盖位置。 在输送药物之后，激活器被设置成在手动操作之前将弹簧锁定在加压状态，并且能够在手动操作时释放用于注射的弹簧。
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公开(公告)号：US09233215B2
公开(公告)日：2016-01-12
申请号：US13806965
申请日：2011-06-20
CPC分类号： A61M5/484 , A61M5/20 , A61M5/2033 , A61M5/3158 , A61M5/321 , A61M5/3234 , A61M5/3243 , A61M5/326 , A61M5/46 , A61M5/482 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/31508 , A61M2005/3151 , A61M2005/3152
摘要： An auto-injector comprising an elongate housing arranged to contain a syringe and displacing medicament, wherein the syringe is slidably arranged with respect to the housing, spring capable of: pushing a needle from a covered position inside the housing into an advanced position, operating the syringe to supply a dose of medicament, and retracting the syringe with the needle into the covered position. Activating means is arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection. The spring is a single drive spring arranged for advancing the needle and for injecting the dose of medicament via a plunger. A damper is arranged with the plunger by a spline so as to cause rotation of either the plunger or the damper at least during part of a translation of the plunger in proximal direction.
摘要翻译： 一种自动注射器，包括布置成容纳注射器和置换药剂的细长壳体，其中所述注射器相对于所述壳体可滑动地布置，弹簧能够：将针从所述壳体内的覆盖位置推入到前进位置， 注射器以供应一定剂量的药物，并将注射器用针收回到覆盖位置。 激活装置被布置成在手动操作之前将弹簧锁定在加压状态，并且能够在手动操作时释放用于注射的弹簧。 弹簧是布置成用于推进针头并且用于经由柱塞注射剂量的药物的单个驱动弹簧。 至少在柱塞在近端方向平移的部分期间，阻尼器通过花键与柱塞一起布置成使柱塞或阻尼器的旋转。
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公开(公告)号：US20130190694A1
公开(公告)日：2013-07-25
申请号：US13876786
申请日：2011-10-06
CPC分类号： A61M5/31513 , A61M5/2033 , A61M5/3129 , A61M5/31511 , A61M5/3204 , A61M5/3232 , A61M2005/206 , A61M2005/2073 , A61M2005/3107
摘要： The invention refers to an arrangement for coupling a plunger (9) to either a syringe (3) or a stopper (6) arranged in the syringe (3), the arrangement comprising a syringe holder (22) which is slidably arranged in a housing (2), wherein the syringe holder (22) is provided with at least one resilient syringe holder arm (23) arranged distally, the syringe holder arm (23) having an inclined surface for bearing against a shoulder (24), which is arranged at the plunger (9), wherein the syringe holder arm (23) is supportable by an inner surface of the housing (2) in order to prevent it from being flexed outward in a first position and wherein a widened portion (2.1) is provided in the housing (2) for allowing the syringe holder arm (23) to flex outwards and disconnect from the plunger (9) when in a more proximal position so as to switch load of the plunger (9) from the syringe (3) to the stopper (6).
摘要翻译： 本发明涉及一种用于将柱塞（9）连接到设置在注射器（3）中的注射器（3）或止动件（6）的装置，该装置包括注射器保持器（22），其可滑动地布置在壳体 （2），其中所述注射器保持器（22）设置有至少一个向远侧布置的弹性注射器保持器臂（23），所述注射器保持器臂（23）具有用于抵靠肩部（24）的倾斜表面，所述倾斜表面布置 在所述柱塞（9）处，其中所述注射器保持器臂（23）可由所述壳体（2）的内表面支撑，以防止其在第一位置向外弯曲，并且其中提供加宽部分（2.1） 在用于允许注射器保持器臂（23）在更靠近的位置向外弯曲并与柱塞（9）断开的壳体（2）中，以便将柱塞（9）从注射器（3）的负载切换到 止动器（6）。
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公开(公告)号：US20130190693A1
公开(公告)日：2013-07-25
申请号：US13578997
申请日：2011-02-16
IPC分类号： A61M5/32
CPC分类号： A61M5/3245 , A61M5/2033 , A61M5/3146 , A61M5/31575 , A61M5/3202 , A61M5/3204 , A61M5/321 , A61M5/326 , A61M5/422 , A61M5/46 , A61M2005/206 , A61M2005/2073 , A61M2005/31516 , A61M2005/325
摘要： The invention relates to a finger guard (7) for an injection device for administering a dose of a liquid medicament (M), the finger guard (7) comprising two inwardly biased spring arms (8) arranged for bearing against a protective needle shield (5) arrangeable at a hollow needle (4), the finger guard (7) further having a respective locking arm (9) assigned to each spring arm (8) biased in a distal direction (D) thus bearing against the respective spring arm (8) when the protective needle shield (5) is in place, wherein the spring arms (8) are arranged to move inwards when the protective needle shield (5) is removed thus allowing the locking arms (9) to move distally into a position where they prevent the spring arms (8) from being pushed outward again.
摘要翻译： 本发明涉及一种用于给药液体药物（M）的注射装置的手指护罩（7），手指护罩（7）包括两个向内偏置的弹簧臂（8），该弹簧臂布置成抵靠保护性针头护罩 5）可布置在空心针（4）上，手指护罩（7）还具有分配给沿远端方向（D）偏压的每个弹簧臂（8）的相应锁定臂（9），从而抵靠相应的弹簧臂 如图8所示，当保护针护罩（5）处于适当位置时，其中弹簧臂（8）布置成当保护针护罩（5）被移除时向内移动，从而允许锁定臂（9）向远侧移动到位置 在那里它们防止弹簧臂（8）再次向外推。
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公开(公告)号：US09352089B2
公开(公告)日：2016-05-31
申请号：US13807140
申请日：2011-06-27
CPC分类号： A61M5/2033 , A61M5/31511 , A61M5/326 , A61M5/46 , A61M2005/206 , A61M2005/208
摘要： An auto-injector comprising a housing arranged to contain a syringe. The syringe is slidably arranged with respect to the housing, a spring capable of pushing a needle from a covered position into an advanced position, operating the syringe to supply a dose of medicament, and retracting the syringe into a covered position and an activator. The spring is arranged to be grounded in the housing for advancing the needle and for injecting the dose of medicament. The drive spring grounded in the housing switched to its proximal end for retracting the syringe. An interlock sleeve telescoped within the housing. The activator comprises a trigger, wherein the trigger button is locked, thereby preventing actuation when the interlock sleeve is in its proximal position in an as delivered state and wherein translation of the interlock sleeve unlocks the trigger button so as to allow actuation.
摘要翻译： 一种自动注射器，包括布置成容纳注射器的壳体。 注射器相对于壳体可滑动地布置，弹簧能够将针从覆盖位置推入前进位置，操作注射器以供应一定剂量的药物，并将注射器缩回到覆盖位置和活化剂。 弹簧布置成在壳体中接地以推进针头并注射剂量的药物。 接地在壳体中的驱动弹簧切换到其近端以缩回注射器。 在壳体内伸缩的互锁套筒。 激活器包括触发器，其中触发器按钮被锁定，从而当互锁套筒处于处于其传送状态的近端位置时防止致动，并且其中互锁套筒的平移解除触发按钮以允许致动。
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公开(公告)号：US20130317446A1
公开(公告)日：2013-11-28
申请号：US13807140
申请日：2011-06-27
IPC分类号： A61M5/20
CPC分类号： A61M5/2033 , A61M5/31511 , A61M5/326 , A61M5/46 , A61M2005/206 , A61M2005/208
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and retracting the syringe with the needle into the covered position after delivering the medicament, activating means. The spring means is a single drive spring arranged to be grounded at a distal end in the housing for advancing the needle and for injecting the dose of medicament via a plunger. The drive spring has its ground in the housing switched to its proximal end for retracting the syringe. An interlock sleeve is telescoped in the proximal end of the housing. The activating means comprises a trigger button arranged at the distal end of the auto-injector, wherein the trigger button is locked, thereby preventing actuation when the interlock sleeve is in its proximal position in an as delivered state and wherein translation of the interlock sleeve unlocks the trigger button so as to allow actuation.
摘要翻译： 本发明涉及一种用于给药液体药物的自动注射器，其包括：细长壳体，布置成容纳具有中空针头的注射器和用于密封注射器和移位药剂的塞子，其中注射器可滑动地布置有 相对于壳体，弹簧装置能够在启动时：将针从壳体内的覆盖位置推入通过孔口的前进位置并经过近端，操作注射器以供应剂量的药物，并且缩回注射器 在输送药物，激活装置之后，针头进入覆盖位置。 弹簧装置是单个驱动弹簧，其布置成在壳体中的远端处接地，用于推进针头并且用于经由柱塞喷射剂量的药剂。 驱动弹簧在壳体中的地面切换到其近端以缩回注射器。 联锁套筒可伸缩在壳体的近端。 激活装置包括布置在自动注射器的远端处的触发按钮，其中触发按钮被锁定，从而当互锁套筒处于其接近位置处于交付状态时防止致动，并且互锁套筒的平移解锁 触发按钮以允许致动。
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