公开(公告)号：US20230295635A1

公开(公告)日：2023-09-21

申请号：US17966575

申请日：2022-10-14

申请人： McMaster University

发明人： John D. Brennan ,  Monsur Ali ,  Michael Wolfe ,  Dawn White ,  Manali Mukherjee ,  Parameswaran Nair ,  Alfredo Capretta

IPC分类号： C12N15/115 ,  C12Q1/28

CPC分类号： C12N15/115 ,  C12Q1/28 ,  C12N2310/16

摘要： This disclosure relates to DNA aptamers that bind eosinophil peroxidase, including uses thereof, such as in eosinophil peroxidase detection assays. Also provided is a method for detecting the presence of eosinophil peroxidase in a sample, using the DNA aptamers that bind eosinophil peroxidase. Further provided is a kit for detecting the presence of eosinophil peroxidase in a sample, using the DNA aptamers that bind eosinophil peroxidase.

公开(公告)号：US20230257802A1

公开(公告)日：2023-08-17

申请号：US17990445

申请日：2022-11-18

申请人： McMaster University

发明人： Monsur Ali ,  Dawn White ,  Saeed Mohammadi ,  John D. Brennan ,  Yingfu Li ,  Alfredo Capretta

IPC分类号： C12Q1/6837 ,  C12Q1/689

CPC分类号： C12Q1/6837 ,  C12Q1/689

摘要： This disclosure relates to catalytic nucleic acid probes, biosensors and lateral flow biosensor systems and methods and kits of using the probes, biosensors and lateral flow biosensor systems for detecting microorganisms such as Staphylococcus aureus.