公开(公告)号：US12042284B2

公开(公告)日：2024-07-23

申请号：US15878313

申请日：2018-01-23

申请人： MEDTRONIC MINIMED, INC.

发明人： Jia Yao ,  Daniel E. Pesantez ,  Anuradha Biswas Bhatia ,  Akhil Srinivasan ,  Guangping Zhang ,  Andrea Varsavsky ,  Raghavendhar Gautham

IPC分类号： A61B5/1486 ,  A61B5/145 ,  A61L31/04 ,  A61L31/14 ,  C09D5/16 ,  C12Q1/00 ,  C12Q1/26 ,  C12Q1/54 ,  A61B5/00

CPC分类号： A61B5/14865 ,  A61B5/1451 ,  A61B5/14532 ,  A61L31/04 ,  A61L31/14 ,  C09D5/1681 ,  C12Q1/006 ,  C12Q1/26 ,  C12Q1/54 ,  A61B5/41 ,  A61L2400/18

摘要： Embodiments of the invention provide optimized polymeric surfaces adapted for use with implantable medical devices as well as methods for making and using such polymeric surfaces. These polymer surfaces have a constellation of features that function to inhibit or avoid an inflammatory immune response generated by implantable medical devices. Typical embodiments of the invention include an implantable glucose sensor used in the management of diabetes having a polymer surface with the disclosed constellation of features.

公开(公告)号：US20240358294A1

公开(公告)日：2024-10-31

申请号：US18763620

申请日：2024-07-03

申请人： Medtronic MiniMed, Inc.

发明人： Jia Yao ,  Daniel E. Pesantez ,  Anuradha Biswas Bhatia ,  Akhil Srinivasan ,  Guangping Zhang ,  Andrea Varsavsky ,  Raghavendhar Gautham

IPC分类号： A61B5/1486 ,  A61B5/00 ,  A61B5/145 ,  A61L31/04 ,  A61L31/14 ,  C09D5/16 ,  C12Q1/00 ,  C12Q1/26 ,  C12Q1/54

CPC分类号： A61B5/14865 ,  A61B5/1451 ,  A61B5/14532 ,  A61L31/04 ,  A61L31/14 ,  C09D5/1681 ,  C12Q1/006 ,  C12Q1/26 ,  C12Q1/54 ,  A61B5/41 ,  A61L2400/18

摘要： Embodiments of the invention provide optimized polymeric surfaces adapted for use with implantable medical devices as well as methods for making and using such polymeric surfaces. These polymer surfaces have a constellation of features that function to inhibit or avoid an inflammatory immune response generated by implantable medical devices. Typical embodiments of the invention include an implantable glucose sensor used in the management of diabetes having a polymer surface with the disclosed constellation of features.

公开(公告)号：US20190223771A1

公开(公告)日：2019-07-25

申请号：US15878313

申请日：2018-01-23

申请人： MEDTRONIC MINIMED, INC.

发明人： Jia Yao ,  Daniel E. Pesantez ,  Anuradha Biswas Bhatia ,  Akhil Srinivasan ,  Guangping Zhang ,  Andrea Varsavsky ,  Raghavendhar Gautham

IPC分类号： A61B5/1486 ,  A61L31/04 ,  A61L31/14 ,  C12Q1/00 ,  C12Q1/54 ,  C12Q1/26 ,  A61B5/145

摘要： Embodiments of the invention provide optimized polymeric surfaces adapted for use with implantable medical devices as well as methods for making and using such polymeric surfaces. These polymer surfaces have a constellation of features that function to inhibit or avoid an inflammatory immune response generated by implantable medical devices. Typical embodiments of the invention include an implantable glucose sensor used in the management of diabetes having a polymer surface with the disclosed constellation of features.

公开(公告)号：US20160249840A1

公开(公告)日：2016-09-01

申请号：US14632731

申请日：2015-02-26

申请人： Medtronic MiniMed, Inc.

发明人： Daniel E. Pesantez ,  Jia Yao ,  Bradley C. Liang ,  Rajiv Shah

IPC分类号： A61B5/1486 ,  C12Q1/00 ,  A61B5/145 ,  G01N27/327

CPC分类号： A61B5/14865 ,  A61B5/14532 ,  A61B5/14539 ,  C12Q1/005 ,  C12Q1/006 ,  G01N27/3272

摘要： Embodiments of the invention provide amperometric analyte sensor systems comprising a plurality of electrodes including one or more electrodes designed to monitor pH in order to facilitate the sensing of analytes at different pH levels within a sensor environment. Typical embodiments of the invention include glucose oxidase based amperometric sensors used in the management of diabetes.

摘要翻译： 本发明的实施方案提供电流分析物传感器系统，其包括多个电极，包括设计成监测pH的一个或多个电极，以便于感测在传感器环境内的不同pH值下的分析物。 本发明的典型实施方案包括用于治疗糖尿病的基于葡萄糖氧化酶的电流传感器。