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公开(公告)号:US20240358294A1
公开(公告)日:2024-10-31
申请号:US18763620
申请日:2024-07-03
Applicant: Medtronic MiniMed, Inc.
Inventor: Jia Yao , Daniel E. Pesantez , Anuradha Biswas Bhatia , Akhil Srinivasan , Guangping Zhang , Andrea Varsavsky , Raghavendhar Gautham
IPC: A61B5/1486 , A61B5/00 , A61B5/145 , A61L31/04 , A61L31/14 , C09D5/16 , C12Q1/00 , C12Q1/26 , C12Q1/54
CPC classification number: A61B5/14865 , A61B5/1451 , A61B5/14532 , A61L31/04 , A61L31/14 , C09D5/1681 , C12Q1/006 , C12Q1/26 , C12Q1/54 , A61B5/41 , A61L2400/18
Abstract: Embodiments of the invention provide optimized polymeric surfaces adapted for use with implantable medical devices as well as methods for making and using such polymeric surfaces. These polymer surfaces have a constellation of features that function to inhibit or avoid an inflammatory immune response generated by implantable medical devices. Typical embodiments of the invention include an implantable glucose sensor used in the management of diabetes having a polymer surface with the disclosed constellation of features.
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2.
公开(公告)号:US20240189508A1
公开(公告)日:2024-06-13
申请号:US18443207
申请日:2024-02-15
Applicant: Medtronic MiniMed, Inc.
Inventor: Steven C. Jacks , Peter Ajemba , Akhil Srinivasan , Jacob E. Pananen , Sarkis Aroyan , Pablo Vazquez , Tri T. Dang , Ashley N. Sullivan , Raghavendhar Gautham
CPC classification number: A61M5/1723 , A61B5/14532 , A61B5/1495 , A61M5/14244 , A61B5/4839 , A61B2560/0223 , A61B2560/0238 , A61M2005/14208 , G16H20/17
Abstract: Techniques disclosed herein relate to determining a calibrated measurement value indicative of a physiological condition of a patient using sensor calibration data determined based on fabrication measurements. In some embodiments, the techniques involve obtaining one or more electrical signals from a sensing element of a sensing arrangement, where the one or more electrical signals are influenced by a physiological condition in a body of a patient; obtaining calibration data associated with the sensing element, where the calibration data is based on fabrication process measurement data for the sensing element and a calibration model for a certain physiological condition; and determining, using the one or more electrical signals and the calibration data associated with the sensing element, a calibrated output value indicative of the physiological condition.
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公开(公告)号:US20230123613A1
公开(公告)日:2023-04-20
申请号:US17501292
申请日:2021-10-14
Applicant: Medtronic MiniMed, Inc.
Inventor: Ashwin K. Rao , Quyen B. Ong , Michael E. Miller , Sarnath Chattaraj , Guangping Zhang , Poonam Gulati , Ariel Reider , Mohsen Askarinya , Michael N. Missaghi , Chi-En Lin , Xin Heng , Inthirai Somasuntharam , Melissa Tsang , Carlos E. Maldonado , Akhil Srinivasan
IPC: G01N27/327 , C12N9/04 , C12Q1/00 , G01N33/49
Abstract: The invention provides amperometric analyte sensor systems comprising one or more electrodes designed to monitor in vivo levels of 3-hydroxybutyrate (and optionally glucose as well) in order to facilitate the management of diabetic ketoacidosis. The invention further includes compositions, elements and methods useful with such amperometric analyte sensor systems.
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公开(公告)号:US11565044B2
公开(公告)日:2023-01-31
申请号:US16569417
申请日:2019-09-12
Applicant: MEDTRONIC MINIMED, INC.
Inventor: Steven C. Jacks , Peter Ajemba , Akhil Srinivasan , Jacob E. Pananen , Sarkis Aroyan , Pablo Vazquez , Tri T. Dang , Ashley N. Sullivan , Raghavendhar Gautham
Abstract: Medical devices, systems and methods are provided. One method involves obtaining fabrication process measurement data for a plurality of instances of a sensing element, obtaining reference output measurement data from the plurality of instances in response to a reference stimulus, determining a predictive model for a measurement output of the sensing element as a function of fabrication process measurement variables based on the relationship between the fabrication process measurement data and the reference output measurement data, generating a simulated output measurement distribution across a range of the fabrication process measurement variables using the predictive model, identifying performance thresholds for the measurement output based on the simulated output measurement distribution, obtaining output measurement data from the instance of the sensing element in response to the reference stimulus, and verifying the output measurement data satisfies the performance threshold prior to calibrating a subsequent instance of the sensing element.
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5.
公开(公告)号:US20220081752A1
公开(公告)日:2022-03-17
申请号:US17537035
申请日:2021-11-29
Applicant: Medtronic MiniMed, Inc.
Inventor: Akhil Srinivasan , Yifei Wang
IPC: C23C14/00 , C23C14/54 , C23C14/30 , C23C14/34 , C23C14/02 , C23C14/18 , A61B5/145 , C23C14/20 , G01N27/327 , G01N27/411 , C23C14/14 , C23C14/06
Abstract: A method of depositing of a film on a substrate with controlled adhesion. The method comprises depositing the film including metal, wherein the metal is deposited on the substrate using physical vapor deposition at a pressure that achieves a pre-determined adhesion of the film to the substrate. The pre-determined adhesion allows processing of the film into a device while the film is adhered to the substrate but also allows removal of the device from the substrate.
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公开(公告)号:US20190239778A1
公开(公告)日:2019-08-08
申请号:US15892162
申请日:2018-02-08
Applicant: MEDTRONIC MINIMED, INC.
Inventor: Akhil Srinivasan , Barry P. Pham , Robert C. Mucic , Tyler R. Wong
IPC: A61B5/1486 , A61B5/145
CPC classification number: A61B5/1486 , A61B5/0031 , A61B5/14503 , A61B5/14532 , A61B5/1468 , A61B5/14865 , A61B2562/0209 , A61B2562/125 , G01N33/66
Abstract: A single flex double-sided electrode useful in a continuous glucose monitoring sensor. In one example, a counter electrode is placed on the back-side of the flex and a work electrode is placed on the top-side of the sensor flex. The electrode is fabricated on physical vapor deposited metal deposited on a base substrate. Adhesion of the electrode to the base substrate is carefully controlled so that the electrode can be processed on the substrate and subsequently removed from the substrate after processing.
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公开(公告)号:US20240023894A9
公开(公告)日:2024-01-25
申请号:US16579022
申请日:2019-09-23
Applicant: Medtronic MiniMed, Inc.
Inventor: David C. Antonio , Eric Allan Larson , Jose J. Ruelas , Akhil Srinivasan
CPC classification number: A61B5/6833 , A61B5/14503 , A61M5/158 , A61M5/1723 , A61B5/14532 , A61B5/6832 , A61B5/150732 , A61B5/150633 , A61B5/150236 , A61B5/1486 , A61B5/0022 , A61B2562/227 , A61B2560/045 , A61B5/1473
Abstract: This disclosure generally relates to medical devices that include a sensor transmitter assembly that includes a sensor assembly including a sensor module where a first sensor including a first sensor head having at least one first sensor contact pad is combined with a second sensor including a second sensor head having at least one second sensor contact pad. The sensor transmitter assembly also includes a transmitter assembly positioned on a top of the sensor assembly to form a single unit, the transmitter assembly having at least one transmitter contact disposed on a base of the transmitter assembly, where the first sensor contact pad(s) and the second sensor form a connection path with the transmitter contact(s).
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公开(公告)号:US20230240569A1
公开(公告)日:2023-08-03
申请号:US18296198
申请日:2023-04-05
Applicant: Medtronic MiniMed, Inc.
Inventor: Akhil Srinivasan , Tyler R. Wong , Inthirai Somasuntharam
IPC: A61B5/1473 , A61B5/145 , C23C14/14 , C23C14/35
CPC classification number: A61B5/1473 , A61B5/1451 , C23C14/14 , C23C14/35 , A61B5/14532 , A61B2562/125
Abstract: Embodiments of the invention provide optimized sputtered metallic surfaces adapted for use with implantable medical devices as well as methods for making and using such polymeric surfaces. These sputtered metallic surfaces have features that function to inhibit or avoid an inflammatory immune response generated by implantable medical devices. Typical embodiments of the invention include an implantable glucose sensor used in the management of diabetes having a sputtered metallic surface adapted to contact an in vivo environment.
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公开(公告)号:US11654235B2
公开(公告)日:2023-05-23
申请号:US16569401
申请日:2019-09-12
Applicant: MEDTRONIC MINIMED, INC.
Inventor: Akhil Srinivasan , Peter Ajemba , Steven C. Jacks , Robert C. Mucic , Tyler R. Wong , Melissa Tsang , Chi-En Lin , Mohsen Askarinya , David Probst
CPC classification number: A61M5/1723 , A61B5/1495 , A61B5/14532 , A61M5/14244 , A61B5/145 , A61B5/4839 , A61B2560/0223 , A61B2560/0228 , A61B2560/0238 , A61M2005/14208 , G16H20/17
Abstract: Medical devices and related systems and methods are provided. A method of calibrating an instance of a sensing element involves obtaining fabrication process measurement data from a substrate having the instance of the sensing element fabricated thereon, obtaining a calibration model associated with the sensing element, determining calibration data associated with the instance of the sensing element for converting the electrical signals into a calibrated measurement parameter based on the fabrication process measurement data using the calibration model, and storing the calibration data in a data storage element associated with the instance of the sensing element.
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公开(公告)号:US11583213B2
公开(公告)日:2023-02-21
申请号:US15892162
申请日:2018-02-08
Applicant: MEDTRONIC MINIMED, INC.
Inventor: Akhil Srinivasan , Barry P. Pham , Robert C. Mucic , Tyler R. Wong
IPC: A61B5/1486 , A61B5/145 , G01N33/66 , A61B5/00 , A61B5/1468
Abstract: A single flex double-sided electrode useful in a continuous glucose monitoring sensor. In one example, a counter electrode is placed on the back-side of the flex and a work electrode is placed on the top-side of the sensor flex. The electrode is fabricated on physical vapor deposited metal deposited on a base substrate. Adhesion of the electrode to the base substrate is carefully controlled so that the electrode can be processed on the substrate and subsequently removed from the substrate after processing.
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