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公开(公告)号：US09770502B2
公开(公告)日：2017-09-26
申请号：US14682798
申请日：2015-04-09
Applicant: Merial, Inc.
Inventor： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz
IPC: A61K39/17 , C12N7/00 , A61K39/12 , A61K39/245 , A61K39/00 , A61K39/295
CPC classification number: A61K39/17 , A61K39/12 , A61K39/295 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/55 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N2710/16043 , C12N2710/16334 , C12N2710/16343 , C12N2710/20034 , C12N2720/10034 , C12N2720/10071 , C12N2760/18134 , C12N2760/18171
Abstract: The present invention provides recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain and express antigens of avian pathogens, recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain a mutated gC gene, compositions comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors, polyvalent vaccines comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant Gallid herpesvirus 3 (MDV-2) vectors.
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Patent Agency Ranking
2.发明申请RECOMBINANT HVT VECTORS EXPRESSING ANTIGENS OF AVIAN PATHOGENS AND USES THEREOF 有权表达AVIAN病原体抗原的重组HVT载体及其用途公开(公告)号：US20150283225A1
公开(公告)日：2015-10-08
申请号：US14747419
申请日：2015-06-23
Applicant: MERIAL INC.
Inventor： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz
CPC classification number: A61K39/17 , A61K39/12 , A61K2039/5256 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N15/86 , C12N2710/16334 , C12N2710/16343 , C12N2720/10034 , C12N2720/10071 , C12N2760/18134 , C12N2760/18171 , C12N2800/22
Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors, polyvalent vaccines comprising the recombinant HVT vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
Abstract translation: 本发明提供含有和表达禽类病原体抗原的火鸡（HVT）载体的重组疱疹病毒，包含重组HVT载体的组合物，包含重组HVT载体和一种或多种野生型病毒或重组载体的多价疫苗。 本发明进一步提供针对各种禽类病原体的疫苗接种方法和生产重组HVT载体的方法。
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公开(公告)号：US20170224807A1
公开(公告)日：2017-08-10
申请号：US15434353
申请日：2017-02-16
Applicant: Merial Inc.
Inventor： Michel Bublot , Frederic REYNARD , François-Xavier LE GROS
IPC: A61K39/145 , C12N15/86 , A61K39/275 , A61K39/17 , C12N7/00
CPC classification number: A61K39/145 , A61K39/12 , A61K39/17 , A61K39/275 , A61K2039/5256 , A61K2039/541 , A61K2039/543 , A61K2039/545 , A61K2039/552 , C07K14/005 , C12N7/00 , C12N15/86 , C12N2710/24034 , C12N2760/16034 , C12N2760/16122 , C12N2760/16134 , C12N2760/16171 , C12N2760/18034 , C12N2760/18134 , C12N2760/18143 , C12N2760/18171
Abstract: The present invention encompasses engineered Newcastle Disease Virus (NDV) vaccines or compositions. The vaccine or composition may be a recombinant vaccine. The invention also encompasses recombinant vectors encoding and expressing avian pathogen antigens, more specifically avian influenza proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals, in particular avian, against disease.
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4.发明申请公开(公告)号：US20180163230A1
公开(公告)日：2018-06-14
申请号：US15840764
申请日：2017-12-13
Applicant: MERIAL, INC.
Inventor： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz , Aemro Kassa
IPC: C12N15/869
CPC classification number: C12N15/869 , A61K39/12 , A61K39/155 , A61K39/245 , A61K39/295 , C07K14/03 , C07K14/08 , C12N7/00 , C12N2710/16311 , C12N2710/16334 , C12N2710/16343 , C12N2710/16363 , C12N2720/10034 , C12N2760/16163 , C12N2760/18134 , C12N2760/18163 , C12N2830/20 , C12N2830/50 , C12N2840/203
Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
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5.发明申请RECOMBINANT GALLID HERPESVIRUS 3 (MDV SEROTYPE 2) VECTORS EXPRESSING ANTIGENS OF AVIAN PATHOGENS AND USES THEREOF 有权重组GALLID HERPESVIRUS 3（MDV SEROTYPE 2）向量表达AVIAN病原体的抗原及其用途公开(公告)号：US20160015801A1
公开(公告)日：2016-01-21
申请号：US14682798
申请日：2015-04-09
Applicant: Merial, Inc.
Inventor： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz
CPC classification number: A61K39/17 , A61K39/12 , A61K39/295 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/55 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N2710/16043 , C12N2710/16334 , C12N2710/16343 , C12N2710/20034 , C12N2720/10034 , C12N2720/10071 , C12N2760/18134 , C12N2760/18171
Abstract: The present invention provides recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain and express antigens of avian pathogens, recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain a mutated gC gene, compositions comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors, polyvalent vaccines comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant Gallid herpesvirus 3 (MDV-2) vectors.
Abstract translation: 本发明提供含有禽类病原体抗原的重组Gallid疱疹病毒3（MDV-2）载体，含有突变gC基因的重组Galid疱疹病毒3（MDV-2）载体，包含重组Gallid疱疹病毒3（MDV- 2）载体，包含重组Gallid疱疹病毒3（MDV-2）载体和一种或多种野生型病毒或重组载体的多价疫苗。 本发明进一步提供针对各种禽类病原体的疫苗接种方法和生产重组Gallid疱疹病毒3（MDV-2）载体的方法。
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6.发明授权Recombinant HVT vectors expressing antigens of avian pathogens and uses thereof 有权表达禽类病原体抗原的重组HVT载体及其用途公开(公告)号：US09555096B2
公开(公告)日：2017-01-31
申请号：US14747419
申请日：2015-06-23
Applicant: Merial Inc.
Inventor： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz
CPC classification number: A61K39/17 , A61K39/12 , A61K2039/5256 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N15/86 , C12N2710/16334 , C12N2710/16343 , C12N2720/10034 , C12N2720/10071 , C12N2760/18134 , C12N2760/18171 , C12N2800/22
Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors, polyvalent vaccines comprising the recombinant HVT vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
Abstract translation: 本发明提供含有和表达禽类病原体抗原的火鸡（HVT）载体的重组疱疹病毒，包含重组HVT载体的组合物，包含重组HVT载体和一种或多种野生型病毒或重组载体的多价疫苗。 本发明进一步提供针对各种禽类病原体的疫苗接种方法和生产重组HVT载体的方法。
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