专利检索 ap:("Mesoblast International Sárl") AND inv:"Alicia Mildred Tyrell" 第 1 页

1.

发明授权
Mesenchymal stem cells expressing TNF-α receptors 有权

公开(公告)号：US11821004B2

公开(公告)日：2023-11-21

申请号：US17087124

申请日：2020-11-02

申请人： Mesoblast International Sárl

发明人： Alla Danilkovitch , Diane Carter , Alicia Mildred Tyrell , Simon Bubnic , Michelle Marcelino , Rodney Monroy

IPC分类号： A01N63/00 , G01N33/53 , C12N5/00 , C12N5/0775 , A61K35/28 , A01K67/00 , A61K35/12

CPC分类号： C12N5/0662 , A61K35/28 , C12N5/0663 , A61K2035/122 , C12N2501/25 , G01N2333/525

摘要： Mesenchymal stem cells which express TNF-α receptor Type I in an amount of at least 13 pg/106 cells. Such mesenchymal stem cells inhibit the proliferation of lymphocytes and may be employed, in particular, in the treatment of graft-versus-host disease.