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1.发明申请Systems and methods relating to associating a medical implant with a delivery device 失效将医用植入物与输送装置相关联的系统和方法公开(公告)号：US20050177022A1
公开(公告)日：2005-08-11
申请号：US10991906
申请日：2004-11-17
申请人： Michael Chu , Brian Hanley , Alfred Intoccia , Richard Tah
发明人： Michael Chu , Brian Hanley , Alfred Intoccia , Richard Tah
CPC分类号： A61F2/02 , A61B17/0469 , A61B17/06004 , A61B17/06109 , A61B2017/00349 , A61B2017/00805 , A61B2017/06019 , A61B2017/06042 , A61B2017/06076 , A61B2017/0608 , A61B2017/06085 , A61F2/0045
摘要： The present invention provides devices and methods for associating an implantable sling with a delivery device for delivering the sling to an anatomical location in a patient.
摘要翻译： 本发明提供了用于将可植入吊带与用于将吊索输送到患者中的解剖位置的输送装置相关联的装置和方法。
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公开(公告)号：US08425500B2
公开(公告)日：2013-04-23
申请号：US12468634
申请日：2009-05-19
IPC分类号： A61B18/22
CPC分类号： A61B18/22 , A61B18/24 , A61B2017/00274 , A61B2018/00547 , A61B2018/2272 , G02B6/264 , G02B6/32 , Y10T29/49817
摘要： A method and an apparatus according to an embodiment of the invention includes disposing a cover about a capillary used in a side-firing optical fiber. The cover can be used to protect the capillary when being inserted through an endoscope for medical treatment. In some embodiments, the cover can be a low-profile cover such as a coating made of a light-sensitive polymer or like material. At least a portion of the coating can be removed after insertion by exposing the light-sensitive material to laser energy transmitted from an optical-fiber-core end housed within the capillary. In other embodiments, the cover can be a slideable or moveable low-profile sleeve or metal cover. During insertion, the sleeve or metal cover is positioned over the capillary. After insertion, the sleeve or metal cover is retracted to expose the area to be treated to side-fired laser energy transmitted from the capillary.
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3.发明授权Apparatus and method of designing or optimizing a column for a separation process 有权设计或优化分离过程的色谱柱的设备和方法公开(公告)号：US08650013B2
公开(公告)日：2014-02-11
申请号：US13192192
申请日：2011-07-27
申请人： Brian Hanley
发明人： Brian Hanley
IPC分类号： G06F17/50
CPC分类号： B01D3/4211 , B01D53/1412 , B01D53/1475 , B01D53/18 , G06F17/5009 , G06F2217/16 , Y02C10/06
摘要： A method of designing or optimizing a column for a separation process includes the computer implemented steps of, in a digital processor, providing vapor-side and liquid-side mass transfer coefficient expressions and a mass transfer area expression relevant for a subject column, the vapor-side and liquid-side mass transfer coefficient expressions and the mass transfer area expression having been derived from defining a column average height equivalent to a theoretical plate HETP) as a mathematical relationship in which HETP is proportional to a vapor flow rate, is inversely proportional to effective packing area participating in mass transfer, has a first correction factor with respect to liquid-side mass transfer, and has a second correction factor with respect to vapor-side mass transfer. The expressions are further derived from reducing error of curve fitting HETP empirical data of various columns by using the defined HETP to obtain expressions for the vapor-side and liquid-side mass transfer coefficients and mass transfer area. The method also includes using the provided expressions to determine column height and column width configurations of the subject column, and outputting the determined column height and column width configurations of the subject column.
摘要翻译： 设计或优化用于分离过程的色谱柱的方法包括计算机实现的步骤，在数字处理器中，提供蒸气侧和液体传质系数表达式以及与主题列相关的传质面积表达式，蒸气 侧面和液体质量传递系数表达式以及从定义与理论塔HETP相当的列平均高度得出的传质面积表达式）作为HETP与蒸气流速成比例的数学关系成反比 参与质量传递的有效包装区域具有关于液体传质的第一校正因子，并且具有关于蒸气侧传质的第二校正因子。 通过使用定义的HETP获得各种色谱柱的曲线拟合HETP经验数据的误差，得到蒸气侧和液体传质系数和传质面积的表达式。 该方法还包括使用所提供的表达式来确定主题列的列高度和列宽度配置，并输出所确定的主题列的列高度和列宽度配置。
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公开(公告)号：US20110100794A1
公开(公告)日：2011-05-05
申请号：US12765611
申请日：2010-04-22
申请人： Brian Hanley
发明人： Brian Hanley
IPC分类号： B01D3/42
CPC分类号： B01D3/4211 , B01J19/0033 , B01J19/30 , B01J19/32 , B01J2219/319 , B01J2219/326 , B01J2219/3325
摘要： A flood point for a packed column is determined by providing a data set of gas pressure drop values as a function of gas flow rate values at several liquid flow rates through a packed column, known flood point value for one liquid flow rate, setting flood point values for higher liquid flow rates at values lower than the known flood point value, and setting flood point values for lower liquid flow rates at values higher than the known flood point value, followed by expressing gas flow rates for liquid flow rates as fractions of the flood point value for each respective liquid flow rate. At a constant gas pressure drop, the method then includes calculating an average fractional flood point value for the liquid flow rates and minimizing the standard deviation between the fractional flood point value at different liquid flow rates and the calculated average fractional flood point value by iteratively resetting fractional flood point values and recalculating the average fractional flood point value for the liquid flow rates, thus resulting in determining a flood point for the packed column at any liquid flow rate, and thereby producing a plot of pressure drop as a function of fraction of flood point at any liquid flow rate, or a mathematical expression thereof that can be used in a computer-implemented column design and process modeling.
摘要翻译： 通过提供气体压降值的数据集作为气体流速值的数据集，通过填充柱的几种液体流速，已知的一种液体流量的洪水点值，设定洪水点来确定填充塔的洪水点 在低于已知洪水点值的值下提高液体流速的值，以及在高于已知洪水点值的值下设定较低液体流速的洪峰值，然后将液体流速的气体流速表示为 每个液体流量的泛洪点值。 在恒定的气体压降下，该方法包括计算液体流速的平均分数泛洪点值，并通过迭代重置来最小化不同液体流量下的分数泛洪点值与计算的平均分数洪峰值之间的标准偏差 重新计算液体流量的平均分数泛点值，从而确定任何液体流速下填充塔的洪水点，从而产生作为洪水分数的函数的压降图 指向任何液体流速，或其数学表达式，可用于计算机实现的列设计和过程建模。
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5.发明申请APPARATUS AND METHOD OF DESIGNING OR OPTIMIZING A COLUMN FOR A SEPARATION PROCESS 有权设计或优化分离过程的色谱柱的设备和方法公开(公告)号：US20120029890A1
公开(公告)日：2012-02-02
申请号：US13192192
申请日：2011-07-27
申请人： Brian Hanley
发明人： Brian Hanley
CPC分类号： B01D3/4211 , B01D53/1412 , B01D53/1475 , B01D53/18 , G06F17/5009 , G06F2217/16 , Y02C10/06
摘要： A method of designing or optimizing a column for a separation process includes the computer implemented steps of, in a digital processor, providing vapor-side and liquid-side mass transfer coefficient expressions and a mass transfer area expression relevant for a subject column, the vapor-side and liquid-side mass transfer coefficient expressions and the mass transfer area expression having been derived from defining a column average height equivalent to a theoretical plate HETP) as a mathematical relationship in which HETP is proportional to a vapor flow rate, is inversely proportional to effective packing area participating in mass transfer, has a first correction factor with respect to liquid-side mass transfer, and has a second correction factor with respect to vapor-side mass transfer. The expressions are further derived from reducing error of curve fitting HETP empirical data of various columns by using the defined HETP to obtain expressions for the vapor-side and liquid-side mass transfer coefficients and mass transfer area. The method also includes using the provided expressions to determine column height and column width configurations of the subject column, and outputting the determined column height and column width configurations of the subject column.
摘要翻译： 设计或优化用于分离过程的色谱柱的方法包括计算机实现的步骤，在数字处理器中，提供蒸气侧和液体传质系数表达式以及与主题列相关的传质面积表达式，蒸气 侧面和液体质量传递系数表达式以及从定义与理论塔HETP相当的列平均高度得出的传质面积表达式）作为HETP与蒸气流速成比例的数学关系成反比 参与质量传递的有效包装区域具有关于液体传质的第一校正因子，并且具有关于蒸气侧传质的第二校正因子。 通过使用定义的HETP获得各种色谱柱的曲线拟合HETP经验数据的误差，得到蒸气侧和液体传质系数和传质面积的表达式。 该方法还包括使用所提供的表达式来确定主题列的列高度和列宽度配置，并输出所确定的主题列的列高度和列宽度配置。
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公开(公告)号：US20100198214A1
公开(公告)日：2010-08-05
申请号：US12696930
申请日：2010-01-29
CPC分类号： A61B17/42 , A61B2017/3419 , A61B2017/4216 , A61B2017/4225 , A61B2090/064
摘要： A device for sealing a cervical opening includes a support structure, and a seal coupled to the support structure, the seal having a surface for abutting against tissue next to the cervical opening, wherein the seal is tiltable relative to the support structure. A device for sealing a cervical opening includes a support structure, and a member coupled to the support structure, wherein the member is inflatable to create a seal for abutting against cervical tissue. A device for sealing a cervical opening includes a seal having a surface for contacting tissue next to the cervical opening, an opening formed on the surface of the seal, and a vacuum port, wherein the opening is in fluid communication with the vacuum port.
摘要翻译： 用于密封颈部开口的装置包括支撑结构和联接到支撑结构的密封件，密封件具有用于邻接颈部开口的组织抵靠的表面，其中密封件可相对于支撑结构倾斜。 用于密封颈部开口的装置包括支撑结构和联接到支撑结构的构件，其中构件可充气以产生用于抵靠颈部组织的密封。 用于密封颈部开口的装置包括具有用于接触颈部开口旁边的组织的表面的密封件，形成在密封件的表面上的开口和真空口，其中开口与真空口流体连通。
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公开(公告)号：US20170333104A1
公开(公告)日：2017-11-23
申请号：US15158698
申请日：2016-05-19
申请人： Sean Forde , Sean Arthur McDermott , Brian Hanley
发明人： Sean Forde , Sean Arthur McDermott , Brian Hanley
CPC分类号： A61B18/02 , A61B2017/00469 , A61B2017/00477 , A61B2018/00166 , A61B2018/00172 , A61B2018/00196 , A61B2018/00541 , A61B2018/00738 , A61B2018/00982 , A61B2018/0212 , A61B2090/034 , A61B2090/062 , A61B2090/0811
摘要： The present disclosure pertains to devices and methods for diagnosis and treatment of biological tissue in which the tissue is accessed by a catheter through a working channel of an endoscope and in which the degree of extension of a distal tip of the catheter beyond a distal tip of the endoscope is controlled.
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公开(公告)号：US08597289B2
公开(公告)日：2013-12-03
申请号：US12696930
申请日：2010-01-29
CPC分类号： A61B17/42 , A61B2017/3419 , A61B2017/4216 , A61B2017/4225 , A61B2090/064
摘要： A device for sealing a cervical opening includes a support structure, and a seal coupled to the support structure, the seal having a surface for abutting against tissue next to the cervical opening, wherein the seal is tiltable relative to the support structure. A device for sealing a cervical opening includes a support structure, and a member coupled to the support structure, wherein the member is inflatable to create a seal for abutting against cervical tissue. A device for sealing a cervical opening includes a seal having a surface for contacting tissue next to the cervical opening, an opening formed on the surface of the seal, and a vacuum port, wherein the opening is in fluid communication with the vacuum port.
摘要翻译： 用于密封颈部开口的装置包括支撑结构和联接到支撑结构的密封件，密封件具有用于邻接颈部开口的组织抵靠的表面，其中密封件可相对于支撑结构倾斜。 用于密封颈部开口的装置包括支撑结构和联接到支撑结构的构件，其中构件可充气以产生用于抵靠颈部组织的密封。 用于密封颈部开口的装置包括具有用于接触颈部开口旁边的组织的表面的密封件，形成在密封件的表面上的开口和真空口，其中开口与真空口流体连通。
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公开(公告)号：US08449727B2
公开(公告)日：2013-05-28
申请号：US12765611
申请日：2010-04-22
申请人： Brian Hanley
发明人： Brian Hanley
IPC分类号： B01D3/42
CPC分类号： B01D3/4211 , B01J19/0033 , B01J19/30 , B01J19/32 , B01J2219/319 , B01J2219/326 , B01J2219/3325
摘要： A flood point for a packed column is determined by providing a data set of gas pressure drop values as a function of gas flow rate values at several liquid flow rates through a packed column, known flood point value for one liquid flow rate, setting flood point values for higher liquid flow rates at values lower than the known flood point value, and setting flood point values for lower liquid flow rates at values higher than the known flood point value, followed by expressing gas flow rates for liquid flow rates as fractions of the flood point value for each respective liquid flow rate. At a constant gas pressure drop, the method then includes calculating an average fractional flood point value for the liquid flow rates and minimizing the standard deviation between the fractional flood point value at different liquid flow rates and the calculated average fractional flood point value by iteratively resetting fractional flood point values and recalculating the average fractional flood point value for the liquid flow rates, thus resulting in determining a flood point for the packed column at any liquid flow rate, and thereby producing a plot of pressure drop as a function of fraction of flood point at any liquid flow rate, or a mathematical expression thereof that can be used in a computer-implemented column design and process modeling.
摘要翻译： 通过提供气体压降值的数据集作为气体流速值的数据集，通过填充柱的几种液体流速，已知的一种液体流量的洪水点值，设定洪水点来确定填充塔的洪水点 在低于已知洪水点值的值下提高液体流速的值，以及在高于已知洪水点值的值下设定较低液体流速的洪峰值，然后将液体流速的气体流速表示为 每个液体流量的泛洪点值。 在恒定的气体压降下，该方法包括计算液体流速的平均分数泛洪点值，并通过迭代重置来最小化不同液体流量下的分数泛洪点值与计算的平均分数洪峰值之间的标准偏差 重新计算液体流量的平均分数泛点值，从而确定任何液体流速下填充塔的洪水点，从而产生作为洪水分数的函数的压降图 指向任何液体流速，或其数学表达式，可用于计算机实现的列设计和过程建模。
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公开(公告)号：US07720511B1
公开(公告)日：2010-05-18
申请号：US11748630
申请日：2007-05-15
申请人： Brian Hanley , Choong K Oh
发明人： Brian Hanley , Choong K Oh
CPC分类号： G01S7/02 , H01Q3/04 , H01Q3/2605
摘要： The present invention determines optimal positions of a variable antenna using an artificial intelligence-based genetic algorithm (GA). The GA acquires a fitness value for an individual of a genetic algorithm population by updating positions of the antenna. The population improves through an evolutionary computational process using a fitness measure based on the signal strength. At the end of the process, the system positions the antenna to the best position found by the GA. Therefore, the final position gives exceptionally clear reception for a chosen received frequency.
摘要翻译： 本发明使用基于人工智能的遗传算法（GA）来确定可变天线的最佳位置。 GA通过更新天线的位置来获取遗传算法群体个体的适应度值。 通过使用基于信号强度的适应度测量的进化计算过程改善人口。 在该过程结束时，系统将天线定位在GA发现的最佳位置。 因此，最终位置给出了所选接收频率的非常清晰的接收。
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