-
公开(公告)号：US06787301B2
公开(公告)日：2004-09-07
申请号：US09943093
申请日：2001-08-31
IPC分类号： C12Q100
CPC分类号： B23K26/0736 , B23K2103/32 , B23K2103/50 , G01N1/2813 , G01N2001/045 , G01N2001/2886 , Y10S435/808 , Y10T83/04
摘要： A method and an apparatus for laser microdissection of specimen regions (23) of interest of a specimen (4) are described. In a first step, an incomplete cut line (25) enclosing the specimen region (23) of interest is generated by means of a laser beam (7). At the incomplete point of the cut line (25), there remains a web (26) which joins the specimen region (23) of interest to the surrounding specimen (4). In a second step, the web (26) is severed with a single laser pulse directed onto it, thereby completing the cut line. The specimen region (23) of interest is in that context detached from the specimen (4) and falls by the action of gravity into a collection vessel (19).
摘要翻译： 描述了用于样本（4）的感兴趣的样本区域（23）的激光显微切割的方法和装置。 在第一步骤中，通过激光束（7）产生包围感兴趣的样本区域（23）的不完整切割线（25）。 在切割线（25）的不完整点处，存在将感兴趣的样品区域（23）连接到周围样品（4）的网（26）。 在第二步骤中，用指向其上的单个激光脉冲切断网（26），从而完成切割线。 感兴趣的样本区域（23）在该情况下与试样（4）分离，并且通过重力作用而落入收集容器（19）中。
-
公开(公告)号：US20130027770A1
公开(公告)日：2013-01-31
申请号：US13559778
申请日：2012-07-27
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
IPC分类号： G02B21/06
CPC分类号： G02B21/088 , G02B5/22 , G02B21/125 , G02B21/16
摘要： The invention relates to a microscope illumination method, to a microscope illumination set, comprising a white light LED (4) and a correction filter (6), and to a corresponding microscope system (1) for analysing a sample (10) alternately or simultaneously in transmitted light bright field illumination and in incident light fluorescence illumination, wherein a white light LED (4) is used for the transmitted light bright field illumination, and a correction filter (6) is activated at a location in the illumination beam path of the transmitted light bright field illumination both during transmitted light bright field illumination and during incident light fluorescence illumination, wherein the correction filter (6) has a spectral transmission profile which has a minimum in the wavelength range of at least one maximum of the spectrum of the white light LED (4).
摘要翻译： 本发明涉及一种显微照明方法，涉及一种包括白光LED（4）和校正滤光片（6）的显微照明组件，以及用于交替或同时分析样品（10）的相应显微系统（1） 在透射光明场照明和入射光荧光照明中，其中白光LED（4）用于透射光明场照明，校正滤光片（6）在照明光束路径中的位置被激活 在透射光明场照明期间和在入射光荧光照明期间的透射光明场照明，其中所述校正滤光片（6）具有光谱透射分布，所述光谱透射分布在白色光谱的至少一个最大值的波长范围内具有最小值 灯LED（4）。
-
公开(公告)号：US20080198448A1
公开(公告)日：2008-08-21
申请号：US12032435
申请日：2008-02-15
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
IPC分类号： G02B21/06
CPC分类号： G02B21/16 , G02B21/06 , G02B27/1006
摘要： An arrangement for fluorescence microscopic examination of specimens includes: a fluorescence microscope; an illumination device that includes: a housing including an interface configured to optically couple the housing and the fluorescence microscope; a plurality of light-emitting diodes disposed in the housing; a respective collector disposed downstream of each of the light emitting diodes and configured to generate a directed light flux; and at least one dichroic splitter disposed in the housing, the at least one splitter and the light-emitting diodes being spatially disposed with respect to one another so that the directed light fluxes are combinable via the at least one splitter into a common illumination beam path directed onto the interface; and a logical control device common to the fluorescence microscope and the illumination device.
摘要翻译： 用于荧光显微镜检查的样品的布置包括：荧光显微镜; 一种照明装置，包括：壳体，包括被配置为光耦合所述壳体和所述荧光显微镜的接口; 设置在所述壳体中的多个发光二极管; 设置在每个所述发光二极管的下游并且被配置为产生有向光通量的相应集电极; 以及设置在所述壳体中的至少一个二向色分配器，所述至少一个分离器和所述发光二极管相对于彼此在空间上设置，使得所述定向光束可经由所述至少一个分离器组合成公共照明光束路径 指向界面; 以及荧光显微镜和照明装置通用的逻辑控制装置。
-
公开(公告)号：US08395840B2
公开(公告)日：2013-03-12
申请号：US12844506
申请日：2010-07-27
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
IPC分类号： G02B21/00
CPC分类号： G02B21/248 , G02B7/005 , G02B7/16 , G02B7/1827
摘要： An apparatus for positioning optical components in an optical device and a microscope with such an apparatus are described, comprising a holding device having a plurality of receptacles on which the optical components can be fixed. A stepper motor comprises a motor shaft for rotating the holding device via a toothed belt and therefore positions the optical components. This allows to position optical components in the optical beam path with low noise and in a vibration-free manner.
摘要翻译： 描述了一种用于将光学部件定位在光学装置中的装置和具有这种装置的显微镜，其包括具有多个插座的保持装置，光学部件可以固定在该容器上。 步进电动机包括用于经由齿形带旋转保持装置并因此定位光学部件的电动机轴。 这允许以低噪声和无振动的方式将光学部件定位在光束路径中。
-
公开(公告)号：US07079316B2
公开(公告)日：2006-07-18
申请号：US10840133
申请日：2004-05-06
申请人： Albrecht Weiss , Michael Ganser
发明人： Albrecht Weiss , Michael Ganser
摘要： A microscope includes an interference contrast transmitted-light device having an analyzer disposed in the microscope imaging beam path, the analyzer causing a beam deflection. A fluorescence device is provided, the fluorescence device and the interference contrast transmitted-light device being selectably and alternatively insertable into the imaging beam path. A pair of glass wedge plates are arranged behind the analyzer in the imaging direction so as to compensate to zero for the beam deflection caused by the analyzer.
摘要翻译： 显微镜包括具有设置在显微镜成像光束路径中的分析器的干涉对比透射光装置，分析仪引起光束偏转。 提供荧光装置，荧光装置和干涉对比透射光装置可选地并可替换地插入到成像光束路径中。 一对玻璃楔板在成像方向后面设置在分析仪后面，以便由分析仪引起的光束偏转补偿为零。
-
公开(公告)号：US06907798B2
公开(公告)日：2005-06-21
申请号：US10257153
申请日：2001-03-21
申请人： Michael Ganser , Albrecht Weiss , Ruediger Stenzel
发明人： Michael Ganser , Albrecht Weiss , Ruediger Stenzel
摘要： The invention relates to a device for laser cutting preparations which comprises an XY table (2) that defines a table surface (4). A holding device (14) for accommodating an object support (6) with a preparation (8) is arranged above the table surface (4) and is joined to the XY table (2) in a manner that permits it to be displaced in the Y direction (20a) in the X direction (22a). An open working space (16) is defined between the holding device (14) and the table surface (4). A catching device (10), which has at least one receptacle (12) for catching a preparation part that has been cut out, can be introduced into said working space. The invention also relates to a microscope that is equipped with the aforementioned laser cutting device.
摘要翻译： 本发明涉及一种用于激光切割制品的装置，其包括限定台面（4）的XY工作台（2）。 用于用制备物（8）容纳物体支撑件（6）的保持装置（14）设置在工作台面（4）的上方，并以允许在XY工作台（2）内移动的方式与XY工作台 Y方向（20A）。 在保持装置（14）和台面（4）之间限定开放的工作空间（16）。 具有至少一个用于捕获被切除的准备部件的容器（12）的捕获装置（10）可以被引入到所述工作空间中。 本发明还涉及配备有上述激光切割装置的显微镜。
-
公开(公告)号：US08643711B2
公开(公告)日：2014-02-04
申请号：US12300108
申请日：2007-03-28
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
CPC分类号： G02B21/361
摘要： A microscope comprising a camera connection in a image beam path is suggested. A camera adapter and a camera can be adapted to the camera connection, and the microscope can be used to reproduce the image of a sample on a sensor of the camera. Imaging of the beam path in the camera adapter comprises an intermediate imaging with a pupil plane having reduced beam diameter next to the pupil plane, and at least one optical means can be inserted into the reproduction beam path in the region of the reduced beam cross-section. An optical means or an interchangeable device comprising a plurality of optical means, such as filters, plane-parallel plates or wedge plate, is integrated into the pupil plane in the camera adapter.
摘要翻译： 建议包括图像光束路径中的相机连接的显微镜。 相机适配器和相机可以适应相机连接，并且显微镜可用于在相机的传感器上再现样品的图像。 照相机适配器中的光束路径的成像包括具有瞳孔平面的光瞳面的中间成像，瞳平面的光束直径减小，并且至少一个光学装置可以在缩小光束横截面的区域插入到再现光束路径中， 部分。 包括多个光学装置（诸如滤光器，平面平行板或楔形板）的光学装置或可互换装置被集成到相机适配器中的光瞳平面中。
-
公开(公告)号：US20110026112A1
公开(公告)日：2011-02-03
申请号：US12844506
申请日：2010-07-27
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
IPC分类号： G02B21/00
CPC分类号： G02B21/248 , G02B7/005 , G02B7/16 , G02B7/1827
摘要： An apparatus for positioning optical components in an optical device and a microscope with such an apparatus are described, comprising a holding device having a plurality of receptacles on which the optical components can be fixed. A stepper motor comprises a motor shaft for rotating the holding device via a toothed belt and therefore positions the optical components. This allows to position optical components in the optical beam path with low noise and in a vibration-free manner.
摘要翻译： 描述了一种用于将光学部件定位在光学装置中的装置和具有这种装置的显微镜，其包括具有多个插座的保持装置，光学部件可以固定在该容器上。 步进电动机包括用于经由齿形带旋转保持装置并因此定位光学部件的电动机轴。 这允许以低噪声和无振动的方式将光学部件定位在光束路径中。
-
公开(公告)号：US07379238B2
公开(公告)日：2008-05-27
申请号：US10538522
申请日：2003-11-13
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
IPC分类号： G02B21/00
CPC分类号： G02B21/082
摘要： The invention relates to a reflected-light microscope comprising a light source for generating an illumination light beam, which can be directed through a lens along an illumination beam path onto a sample. Said microscope is provided with imaging optics, which generate a plane that optically corresponds to the pupil plane. At least one attenuation element, which acts in an essentially uniform manner over the entire cross-section of the illumination light beam, can be introduced into the illumination beam path on the optically corresponding plane.
摘要翻译： 本发明涉及一种包括用于产生照明光束的光源的反射光显微镜，其可以沿着照明光束路径被引导到透镜上。 所述显微镜具有成像光学元件，其产生光学对应于瞳孔平面的平面。 在照明光束的整个横截面上以基本上均匀的方式起作用的至少一个衰减元件可被引入光学相应平面上的照明光束路径中。
-
公开(公告)号：US20060209398A1
公开(公告)日：2006-09-21
申请号：US11363916
申请日：2006-02-28
申请人： Albrecht Weiss , Michael Ganser
发明人： Albrecht Weiss , Michael Ganser
IPC分类号： G02B21/06
摘要： An objective for total internal reflection microscopy includes a diaphragm disposed near to or in the plane of the objective pupil. The diaphragm includes a middle area impermeable to illumination light and permeable to detection light of a microscope, and includes an edge area permeable to the illumination light. The illumination light has a focus in the plane of the objective pupil.
-
-
-
-
-
-
-
-
-
搜索结果
75 条记录 (耗时 0.026 秒)
