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公开(公告)号：US08922885B2
公开(公告)日：2014-12-30
申请号：US12032435
申请日：2008-02-15
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
CPC分类号： G02B21/16 , G02B21/06 , G02B27/1006
摘要： An arrangement for fluorescence microscopic examination of specimens includes: a fluorescence microscope; an illumination device that includes: a housing including an interface configured to optically couple the housing and the fluorescence microscope; a plurality of light-emitting diodes disposed in the housing; a respective collector disposed downstream of each of the light emitting diodes and configured to generate a directed light flux; and at least one dichroic splitter disposed in the housing, the at least one splitter and the light-emitting diodes being spatially disposed with respect to one another so that the directed light fluxes are combinable via the at least one splitter into a common illumination beam path directed onto the interface; and a logical control device common to the fluorescence microscope and the illumination device.
摘要翻译： 用于荧光显微镜检查的样品的布置包括：荧光显微镜; 一种照明装置，包括：壳体，包括被配置为光耦合所述壳体和所述荧光显微镜的接口; 设置在所述壳体中的多个发光二极管; 设置在每个所述发光二极管的下游并且被配置为产生有向光通量的相应集电极; 以及设置在所述壳体中的至少一个二向色分配器，所述至少一个分离器和所述发光二极管相对于彼此在空间上设置，使得所述定向光束可经由所述至少一个分离器组合成公共照明光束路径 指向界面; 以及荧光显微镜和照明装置通用的逻辑控制装置。
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公开(公告)号：US20090195646A1
公开(公告)日：2009-08-06
申请号：US12300108
申请日：2007-03-28
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
CPC分类号： G02B21/361
摘要： A microscope comprising a camera connection in a image beam path is suggested. A camera adapter and a camera can be adapted to the camera connection, and the microscope can be used to reproduce the image of a sample on a sensor of the camera. Imaging of the beam path in the camera adapter comprises an intermediate imaging with a pupil plane having reduced beam diameter next to the pupil plane, and at least one optical means can be inserted into the reproduction beam path in the region of the reduced beam cross-section. An optical means or an interchangeable device comprising a plurality of optical means, such as filters, plane-parallel plates or wedge plate, is integrated into the pupil plane in the camera adapter.
摘要翻译： 建议包括图像光束路径中的相机连接的显微镜。 相机适配器和相机可以适应相机连接，并且显微镜可用于在相机的传感器上再现样品的图像。 照相机适配器中的光束路径的成像包括具有瞳孔平面的光瞳面的中间成像，瞳平面的光束直径减小，并且至少一个光学装置可以在缩小光束横截面的区域插入到再现光束路径中， 部分。 包括多个光学装置（诸如滤光器，平面平行板或楔形板）的光学装置或可互换装置被集成到相机适配器中的光瞳平面中。
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公开(公告)号：US06545765B1
公开(公告)日：2003-04-08
申请号：US09708778
申请日：2000-11-08
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
IPC分类号： G01B1106
CPC分类号： G01B11/0616
摘要： A method and an apparatus for measuring thickness of transparent films is described in which an illumination beam is directed through an objective onto an object comprising a transparent film. A structured focusing aid is disposed in the illumination beam, a camera is disposed in an imaging beam. The focusing aid and the camera each are disposed in locations conjugated with the focal plane of the objective. The focal plane of the objective is displaced stepwise through the object. At each position, a camera image is recorded and its focus score is determined, the image of the focusing aid being used as the contrast indicator. The positions with maximal focus scores are assigned to the locations of the interfaces. The thickness of the transparent film is calculated from the difference between the positions of its interfaces.
摘要翻译： 描述了一种用于测量透明膜的厚度的方法和装置，其中将照明光束通过物镜引导到包括透明膜的物体上。 结构化聚焦辅助设置在照明光束中，照相机设置在成像光束中。 聚焦辅助器和照相机各自设置在与物镜的焦平面共轭的位置。 物镜的焦平面通过物体逐步移位。 在每个位置，记录摄像机图像并确定其对焦分数，聚焦辅助图像被用作对比度指示器。 具有最大聚焦分数的位置被分配给接口的位置。 透明膜的厚度根据其界面的位置之间的差异来计算。
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公开(公告)号：US06369939B1
公开(公告)日：2002-04-09
申请号：US09555844
申请日：2000-06-05
申请人： Albrecht Weiss , Michael Ganser , Helmut Rühl , Manfred Gilbert
发明人： Albrecht Weiss , Michael Ganser , Helmut Rühl , Manfred Gilbert
IPC分类号： G02B2112
CPC分类号： G02B21/086
摘要： An illumination system (1) for a microscope, in which a first light source (2), a collector lens (3), an aperture diaphragm (4), and a condenser lens ((5) are arranged in the illumination beam path (6), is described. The illumination light is directed through the aperture diaphragm (4) via the condenser lens (5) into the object plane (9). Arranged in the illumination beam path (6) on the optical axis (20) is a second light source (8) that is imaged at infinity by the condenser lens (5).
摘要翻译： 一种用于显微镜的照明系统（1），其中第一光源（2），集光透镜（3），孔径光阑（4）和聚光透镜（（5））布置在照明光束路径 照明光通过聚光透镜（5）通过孔径光阑（4）引导到物平面（9）中，在光轴（20）上的照明光束路径（6）中排列为 由聚光透镜（5）在无限远处成像的第二光源（8）。
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公开(公告)号：US08395840B2
公开(公告)日：2013-03-12
申请号：US12844506
申请日：2010-07-27
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
IPC分类号： G02B21/00
CPC分类号： G02B21/248 , G02B7/005 , G02B7/16 , G02B7/1827
摘要： An apparatus for positioning optical components in an optical device and a microscope with such an apparatus are described, comprising a holding device having a plurality of receptacles on which the optical components can be fixed. A stepper motor comprises a motor shaft for rotating the holding device via a toothed belt and therefore positions the optical components. This allows to position optical components in the optical beam path with low noise and in a vibration-free manner.
摘要翻译： 描述了一种用于将光学部件定位在光学装置中的装置和具有这种装置的显微镜，其包括具有多个插座的保持装置，光学部件可以固定在该容器上。 步进电动机包括用于经由齿形带旋转保持装置并因此定位光学部件的电动机轴。 这允许以低噪声和无振动的方式将光学部件定位在光束路径中。
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公开(公告)号：US08164829B2
公开(公告)日：2012-04-24
申请号：US11569651
申请日：2005-04-07
申请人： Michael Ganser
发明人： Michael Ganser
CPC分类号： G02B21/18
摘要： A system for acquiring and displaying images of preparations is provided. The system includes a first and second illumination device, each including an illumination source defining a respective illumination beam path amid configured to emit light to illuminate the preparation. A camera and a display for displaying a portion of the preparation are further provided. The preparation can be placed on a stage that is movable in x and y coordinate directions. The frame is also provided with a combining device configured to combine the first imaging beam path and the second imaging beam path, and direct them to the camera.
摘要翻译： 提供了一种获取和显示准备图像的系统。 该系统包括第一和第二照明装置，每个照明装置包括照明源，该照明源限定相应的照明光束路径，配置为发射光以照亮准备物。 还提供了一种用于显示制剂的一部分的照相机和显示器。 该制剂可以放置在可在x和y坐标方向上移动的台上。 框架还设置有组合装置，其被配置为组合第一成像光束路径和第二成像光束路径，并将其引导到相机。
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7.发明授权公开(公告)号：US07091990B2
公开(公告)日：2006-08-15
申请号：US10496344
申请日：2002-11-28
申请人： Michael Ganser , Joachim Wesner
发明人： Michael Ganser , Joachim Wesner
IPC分类号： G06T15/00
CPC分类号： B82Y15/00 , G06T5/003 , G06T2207/10056
摘要： A method for blind deconvolution of microscopic images in which only a single parameter is varied for the estimation of the PSF. The single parameter takes account of the optical properties of the environment of the object (40) between the objective (20) of the microscope (1) and the region above the object. The single parameter represents a functional relationship among the parameters of the individual layers.
摘要翻译： 一种用于微观图像的盲解卷积方法，其中仅改变单个参数以用于PSF的估计。 单个参数考虑了显微镜（1）的物镜（20）和物体上方的区域（40）之间的物体（40）的环境的光学性质。 单个参数表示各层参数之间的函数关系。
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公开(公告)号：US07079316B2
公开(公告)日：2006-07-18
申请号：US10840133
申请日：2004-05-06
申请人： Albrecht Weiss , Michael Ganser
发明人： Albrecht Weiss , Michael Ganser
摘要： A microscope includes an interference contrast transmitted-light device having an analyzer disposed in the microscope imaging beam path, the analyzer causing a beam deflection. A fluorescence device is provided, the fluorescence device and the interference contrast transmitted-light device being selectably and alternatively insertable into the imaging beam path. A pair of glass wedge plates are arranged behind the analyzer in the imaging direction so as to compensate to zero for the beam deflection caused by the analyzer.
摘要翻译： 显微镜包括具有设置在显微镜成像光束路径中的分析器的干涉对比透射光装置，分析仪引起光束偏转。 提供荧光装置，荧光装置和干涉对比透射光装置可选地并可替换地插入到成像光束路径中。 一对玻璃楔板在成像方向后面设置在分析仪后面，以便由分析仪引起的光束偏转补偿为零。
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公开(公告)号：US20060056013A1
公开(公告)日：2006-03-16
申请号：US10538522
申请日：2003-11-13
申请人： Michael Ganser , Albecht Weiss
发明人： Michael Ganser , Albecht Weiss
IPC分类号： G02B21/00
CPC分类号： G02B21/082
摘要： The invention relates to a reflected-light microscope comprising a light source for generating an illumination light beam, which can be directed through a lens along an illumination beam path onto a sample. Said microscope is provided with imaging optics, which generate a plane that optically corresponds to the pupil plane. At least one attenuation element, which acts in an essentially uniform manner over the entire cross-section of the illumination light beam, can be introduced into the illumination beam path on the optically corresponding plane.
摘要翻译： 本发明涉及一种包括用于产生照明光束的光源的反射光显微镜，其可以沿着照明光束路径被引导到透镜上。 所述显微镜具有成像光学元件，其产生光学对应于瞳孔平面的平面。 在照明光束的整个横截面上以基本上均匀的方式起作用的至少一个衰减元件可被引入光学相应平面上的照明光束路径中。
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公开(公告)号：US06907798B2
公开(公告)日：2005-06-21
申请号：US10257153
申请日：2001-03-21
申请人： Michael Ganser , Albrecht Weiss , Ruediger Stenzel
发明人： Michael Ganser , Albrecht Weiss , Ruediger Stenzel
摘要： The invention relates to a device for laser cutting preparations which comprises an XY table (2) that defines a table surface (4). A holding device (14) for accommodating an object support (6) with a preparation (8) is arranged above the table surface (4) and is joined to the XY table (2) in a manner that permits it to be displaced in the Y direction (20a) in the X direction (22a). An open working space (16) is defined between the holding device (14) and the table surface (4). A catching device (10), which has at least one receptacle (12) for catching a preparation part that has been cut out, can be introduced into said working space. The invention also relates to a microscope that is equipped with the aforementioned laser cutting device.
摘要翻译： 本发明涉及一种用于激光切割制品的装置，其包括限定台面（4）的XY工作台（2）。 用于用制备物（8）容纳物体支撑件（6）的保持装置（14）设置在工作台面（4）的上方，并以允许在XY工作台（2）内移动的方式与XY工作台 Y方向（20A）。 在保持装置（14）和台面（4）之间限定开放的工作空间（16）。 具有至少一个用于捕获被切除的准备部件的容器（12）的捕获装置（10）可以被引入到所述工作空间中。 本发明还涉及配备有上述激光切割装置的显微镜。
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