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    Automated laboratory system
    1.
    发明授权
    Automated laboratory system 有权
    自动化实验室系统

    公开(公告)号：US08865474B2

    公开(公告)日：2014-10-21

    申请号：US11429888

    申请日：2006-05-08

    申请人： Michael Paschetto ,  Peter Massaro ,  Jeff Boot ,  David Wilson

    发明人： Michael Paschetto ,  Peter Massaro ,  Jeff Boot ,  David Wilson

    IPC分类号： G01N33/559 ,  G01N35/00 ,  G01N27/447 ,  B01L3/02 ,  G01N35/04

    CPC分类号： G01N35/0099 ,  B01L3/0244 ,  B01L3/0275 ,  G01N27/44704 ,  G01N27/44743 ,  G01N27/44747 ,  G01N27/44782 ,  G01N35/04 ,  Y10T436/25375

    摘要： An automated laboratory system and method allow high-throughput and fully automated processing of materials, such as liquids including genetic materials. The invention includes a variety of aspects that may be combined into a single system. For example, processing may be performed by a plurality of robotic-equipped modular stations, where each modular station has its own unique environment in which processes are performed. Transport devices, such as conveyor belts, may move objects between modular stations, saving movement for robots in the modular stations. Gels used for gel electrophoresis may be extruded, thus decreasing the time needed to form such gels. Robotically-operated well forming tools allow wells to be formed in gels in a registered and accurate way.

    摘要翻译： 自动化实验室系统和方法允许对诸如包括遗传物质在内的液体进行高通量和全自动化处理。 本发明包括可以组合成单个系统的各种方面。 例如，处理可以由多个装有机器人的模块化站来执行，其中每个模块站具有其自己的执行过程的独特环境。 诸如传送带之类的运输设备可以在模块化站之间移动物体，从而节省模块化站中机器人的运动。 可以挤出用于凝胶电泳的凝胶，从而减少形成这种凝胶所需的时间。 机器人操作的成型工具允许以注册和准确的方式在凝胶中形成孔。

    Automated laboratory system
    2.
    发明申请
    Automated laboratory system 有权
    自动化实验室系统

    公开(公告)号：US20060201810A1

    公开(公告)日：2006-09-14

    申请号：US11429888

    申请日：2006-05-08

    申请人： Michael Paschetto ,  Peter Massaro ,  Jeff Boot ,  David Wilson

    发明人： Michael Paschetto ,  Peter Massaro ,  Jeff Boot ,  David Wilson

    IPC分类号： B29C47/00 ,  B01D57/02 ,  G01N27/447

    CPC分类号： G01N35/0099 ,  B01L3/0244 ,  B01L3/0275 ,  G01N27/44704 ,  G01N27/44743 ,  G01N27/44747 ,  G01N27/44782 ,  G01N35/04 ,  Y10T436/25375

    摘要： An automated laboratory system and method allow high-throughput and fully automated processing of materials, such as liquids including genetic materials. The invention includes a variety of aspects that may be combined into a single system. For example, processing may be performed by a plurality of robotic-equipped modular stations, where each modular station has its own unique environment in which processes are performed. Transport devices, such as conveyor belts, may move objects between modular stations, saving movement for robots in the modular stations. Gels used for gel electrophoresis may be extruded, thus decreasing the time needed to form such gels. Robotically-operated well forming tools allow wells to be formed in gels in a registered and accurate way.

    摘要翻译： 自动化实验室系统和方法允许对诸如包括遗传物质在内的液体进行高通量和全自动化处理。 本发明包括可以组合成单个系统的各种方面。 例如，处理可以由多个装有机器人的模块化站来执行，其中每个模块站具有其自己的执行过程的独特环境。 诸如传送带之类的运输设备可以在模块化站之间移动物体，从而节省模块化站中机器人的运动。 可以挤出用于凝胶电泳的凝胶，从而减少形成这种凝胶所需的时间。 机器人操作的成型工具允许以注册和准确的方式在凝胶中形成孔。

    SURGICAL TOOL
    4.
    发明申请
    SURGICAL TOOL 有权
    手术工具

    公开(公告)号：US20170014131A1

    公开(公告)日：2017-01-19

    申请号：US14934878

    申请日：2015-11-06

    申请人： Keith Edward Martin ,  Frank M. Fago ,  David Wilson

    发明人： Keith Edward Martin ,  Frank M. Fago ,  David Wilson

    IPC分类号： A61B17/10

    CPC分类号： A61B17/1285 ,  A61B17/00234 ,  A61B17/10 ,  A61B17/1227 ,  A61B34/71 ,  A61B2017/00243 ,  A61B2017/00323 ,  A61B2017/00584 ,  A61B2017/0069 ,  A61B2017/2902 ,  A61B2017/2927 ,  A61B2017/2937 ,  A61B2017/2939

    摘要： A medical instrument including a first joint including a first member and a second member, the first member configured to be repositionable with respect to the second member in a first degree of freedom, a second joint operatively coupled to the first joint, the second joint including a third member and a fourth member, the third member configured to be repositionable with respect to the fourth member in a second degree of freedom, a pair of repositionable jaws operatively coupled to the first joint and the second joint, an open-ended occlusion clip detachably mounted to the pair of repositionable jaws, and a controller operatively coupled to the first joint, the second joint, and the pair of repositionable jaws, the controller including a control with a line operatively coupled to the first and second jaws in at least a gun tackle pulley configuration.

    摘要翻译： 一种医疗器械，包括包括第一构件和第二构件的第一接头，所述第一构件被构造成在第一自由度中可相对于所述第二构件重新定位，第二接头可操作地联接到所述第一接头，所述第二接头包括 第三构件和第四构件，所述第三构件被构造成能够以第二自由度相对于所述第四构件重新定位，可操作地联接到所述第一接头和所述第二接头的一对可重定位爪，开口闭塞夹 可拆卸地安装到一对可重定位爪上，以及控制器，其可操作地联接到第一接头，第二接头和一对可重定位爪，控制器包括控制器，该控制器具有可操作地连接到第一和第二钳口的至少一个 枪滑轮配置。

    ANTI-PAMP THERAPEUTIC ANTIBODIES
    10.
    发明申请
    ANTI-PAMP THERAPEUTIC ANTIBODIES 审中-公开
    抗抑郁治疗抗体

    公开(公告)号：US20110301332A1

    公开(公告)日：2011-12-08

    申请号：US13001744

    申请日：2009-07-01

    申请人： David Wilson ,  Tetsuya Taura

    发明人： David Wilson ,  Tetsuya Taura

    IPC分类号： C07K16/18 ,  C12N5/18

    CPC分类号： C07K16/26 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/56 ,  C07K2317/76 ,  C07K2317/92

    摘要： The invention relates to antibodies and antigen-binding fragments thereof which bind to proadrenomedullin N-terminal peptide (“PAMP”). Furthermore, the invention comprises monoclonal antibody EGX-P-E9 as well as engineered variants thereof, including chimeric, humanized or de-immunized versions thereof. The antibodies of the invention are useful for inhibiting the physiological activities of PAMP as well as in diagnosis of PAMP-responsive conditions.

    摘要翻译： 本发明涉及与前肾上腺髓质素N-末端肽（“PAMP”）结合的抗体及其抗原结合片段。 此外，本发明包括单克隆抗体EGX-P-E9及其工程变体，包括其嵌合，人源化或去免疫的形式。 本发明的抗体可用于抑制PAMP的生理活性以及PAMP反应性病症的诊断。