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公开(公告)号:US20050218536A1
公开(公告)日:2005-10-06
申请号:US11093819
申请日:2005-03-30
申请人: Michael Quinn , Gregory Carlson , Barry Atkins
发明人: Michael Quinn , Gregory Carlson , Barry Atkins
CPC分类号: G02B1/10 , B29C41/003 , B29D11/00048 , B29D11/00317 , B29K2083/005 , B29K2105/0014 , B29K2105/0032 , B29K2105/0061 , B29L2009/00 , B29L2011/0041 , C09D11/107 , G02B1/043 , C08L83/04
摘要: The present invention provides a method for making colored silicone hydrogel contact lenses. The method of the invention comprises the steps of: (a) applying a color coat to at least a portion of at least one of molding surfaces of a lens mold with an ink, wherein the ink comprises at least one colorant, a binder polymer, an adhesion promoter, and optionally a diluent, wherein the binder polymer is a copolymerization product of a polymerizable mixture including (i) at least one hydrophilic vinylic monomer; (ii) at least one functionalizing vinylic monomer containing at least one functional group selected from the group consisting of hydroxyl group —OH, amino group —NHR (wherein R is hydrogen or C1 to C8 alkyl), carboxylic group —COOH, epoxy group, amide group —CONHR, and combinations thereof; (iii) at least one silicone-containing vinylic monomer or macromer, and (iv) optionally one or more components selected from the group consisting of a polymerization initiator, a chain transfer agent, and a solvent, wherein the mold has a lens-forming cavity between the molding surfaces, wherein the colored coat contains a first surface exposed to the interior of the lens-forming cavity and a second surface in contact with the molding surface; (b) curing the ink printed on the mold; (c) dispensing a silicone hydrogel lens-forming material into the lens-forming cavity of the mold; (d) curing the lens-forming material within the lens-forming cavity to form the contact lens, whereby the colored coat detaches from the molding surface and becomes integral with the body of the contact lens.
摘要翻译: 本发明提供一种制备有色硅酮水凝胶隐形眼镜的方法。 本发明的方法包括以下步骤:(a)将彩色涂层施加到具有油墨的透镜模具的至少一个模制表面的至少一部分上,其中所述油墨包括至少一种着色剂,粘合剂聚合物, 粘合促进剂和任选的稀释剂,其中粘合剂聚合物是可聚合混合物的共聚产物,其包含(i)至少一种亲水性乙烯基单体; (ii)至少一种官能化乙烯基单体,其含有至少一个选自羟基-OH,氨基-NHR(其中R是氢或C 1至C 1至C 1)的官能团, 烷基),羧基-COOH,环氧基,酰胺基-CONHR及其组合; (iii)至少一种含硅酮的乙烯基单体或大分子单体,和(iv)任选的一种或多种选自聚合引发剂,链转移剂和溶剂的组分,其中模具具有透镜形成 模制表面之间的空腔,其中着色涂层包含暴露于透镜形成腔的内部的第一表面和与模制表面接触的第二表面; (b)固化印在模具上的油墨; (c)将硅酮水凝胶透镜形成材料分配到模具的透镜形成腔中; (d)固化透镜形成腔内的透镜形成材料以形成隐形眼镜,由此着色涂层从模制表面脱离并与隐形眼镜的主体成一体。
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公开(公告)号:US20060077341A1
公开(公告)日:2006-04-13
申请号:US11226604
申请日:2005-09-14
申请人: Barry Atkins , Norbert Doerr , Alfred Fischer , Michael Quinn , Roland Schmieder , Robert Tucker
发明人: Barry Atkins , Norbert Doerr , Alfred Fischer , Michael Quinn , Roland Schmieder , Robert Tucker
IPC分类号: G02C7/04
CPC分类号: B29D11/00865 , B29D11/00903 , D06P5/003 , D06P5/007 , D06P5/2005 , G02B1/043
摘要: The invention provides a method for producing colored contact lenses with high quality color images. The method of the invention comprises the steps of (a) providing a water based ink in at least one cliche wherein a pattern to be printed on the contact lens has been created; (b) transferring the water based ink from the cliché to at least a surface of at least a contact lens forming mold by means of at least a transfer pad; (c) at least partially curing the ink transferred on the mold to form a colored film; (d) dispensing a hydrogel lens-forming material into a lens-forming cavity of the mold; and (e) curing the lens-forming material within the lens-forming cavity to form the contact lens, whereby the colored film detaches from the molding surface and becomes integral with the body of the contact lens; characterized in that the relative air humidity in the immediate vicinities of the transfer pad/s is kept higher than 50% at standard temperature and pressure conditions during ink transfer.
摘要翻译: 本发明提供一种生产具有高质量彩色图像的彩色隐形眼镜的方法。 本发明的方法包括以下步骤:(a)在至少一个刻薄中提供水性油墨,其中已经形成要被印刷在隐形眼镜上的图案; (b)借助于至少一个转印垫将水基油墨从陈年代转移到至少一个隐形眼镜成型模的表面; (c)至少部分地固化在模具上转印的油墨以形成着色膜; (d)将水凝胶透镜形成材料分配到模具的透镜形成腔中; 和(e)固化透镜形成腔内的透镜形成材料以形成隐形眼镜,由此着色膜从模制表面脱离并与隐形眼镜的主体成一体; 其特征在于,在墨水转印期间,在标准温度和压力条件下,传送垫的紧邻附近的相对空气湿度保持高于50%。
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公开(公告)号:US07278736B2
公开(公告)日:2007-10-09
申请号:US11065145
申请日:2005-02-23
申请人: Gerardo Ocampo , Michael Quinn , Barry Atkins
发明人: Gerardo Ocampo , Michael Quinn , Barry Atkins
IPC分类号: G02C7/04
CPC分类号: B29D11/00317 , G02C7/046
摘要: The invention is directed to a colored contact lens designed for modifying or enhancing a wearer's eye color while giving the wearer's eyes an improved lively appearance (or more lively or vivacious appearance). In particular, a colored contact lens of the invention may impart to a wearer's eye color both a natural appearance with an emotional dimension such as sophistication, depth, well-being, honesty with intimacy, or combinations thereof. The invention also provides methods and kits for making a colored contact lens of the invention.
摘要翻译: 本发明涉及一种设计用于改善或增强佩戴者眼睛颜色的彩色隐形眼镜,同时给予佩戴者眼睛改善的活泼外观(或更活泼或活泼的外观)。 特别地,本发明的有色隐形眼镜可以赋予佩戴者眼睛颜色既具有复杂性,深度,幸福感,亲密感的情感维度的自然外观或其组合。 本发明还提供了用于制造本发明的有色隐形眼镜的方法和试剂盒。
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公开(公告)号:US20060065138A1
公开(公告)日:2006-03-30
申请号:US11226725
申请日:2005-09-14
申请人: Robert Tucker , Sandra Corti , Michael Quinn , Barry Atkins
发明人: Robert Tucker , Sandra Corti , Michael Quinn , Barry Atkins
IPC分类号: B41F17/00
CPC分类号: C09D11/101 , B41F17/001
摘要: The invention provides a method for producing colored contact lenses with relatively high quality color images. The method of the invention comprises the steps of: (a) obtaining a water based ink having a viscosity of greater than about 100 centipoise (cps) and comprising at least one colorant, a water-soluble binder polymer having ethylenically unsaturated groups, an initiator, and a surfactant, wherein the surfactant is present in an amount sufficient to provide the ink a dynamic surface tension of less than about 40 dyne/cm at surface age of about 1 second, and wherein the initiator is present in an amount sufficient to allow the ink to be cured with an energy exposure which is comparable with an energy exposure required for curing the lens-forming material; (b) applying the ink, by using pad transfer printing technique, to at least a portion of at least one of molding surfaces of a lens mold to form a colored coat; (c) actinically curing the ink printed on the mold to form a colored film, wherein the printed ink is cured to an extent so that no noticeable color smearing is observed by examination with naked eyes; (d) dispensing a lens-forming material into the lens-forming cavity of the mold; and (e) actinically or thermally curing the lens-forming material within the lens-forming cavity to form the contact lens, whereby the colored film detaches from the molding surface and becomes integral with the body of the contact lens, wherein the colored film becomes part of one of the anterior and posterior surface of the colored contact lens and has a good adhesion to the lens.
摘要翻译: 本发明提供一种生产具有较高质量彩色图像的有色隐形眼镜的方法。 本发明的方法包括以下步骤:(a)获得粘度大于约100厘泊(cps)并包含至少一种着色剂的水基油墨,具有烯属不饱和基团的水溶性粘合剂聚合物,引发剂 和表面活性剂,其中表面活性剂的存在量足以提供墨水在大约1秒的表面老化时小于约40达因/厘米的动态表面张力,并且其中引发剂的存在量足以允许 能够暴露于与固化透镜形成材料所需的能量暴露相当的能量曝光的油墨; (b)通过使用垫转移印刷技术将油墨施加到透镜模具的至少一个模制表面的至少一部分以形成着色涂层; (c)对印刷在模具上的油墨进行光固化以形成着色膜,其中印刷油墨固化至一定程度,以便用肉眼观察不到明显的颜色污迹; (d)将镜片形成材料分配到模具的透镜形成腔中; 和(e)在透镜形成腔内光学或热固化透镜形成材料以形成隐形眼镜,由此着色膜与成型表面分离并与隐形眼镜的主体成一体,其中着色膜变为 彩色隐形眼镜的前表面和后表面之一的一部分,并且对透镜具有良好的粘附性。
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公开(公告)号:US20050185134A1
公开(公告)日:2005-08-25
申请号:US11065145
申请日:2005-02-23
申请人: Gerardo Ocampo , Michael Quinn , Barry Atkins
发明人: Gerardo Ocampo , Michael Quinn , Barry Atkins
CPC分类号: B29D11/00317 , G02C7/046
摘要: The invention is directed to a colored contact lens designed for modifying or enhancing a wearer's eye color while giving the wearer's eyes an improved lively appearance (or more lively or vivacious appearance). In particular, a colored contact lens of the invention may impart to a wearer's eye color both a natural appearance with an emotional dimension such as sophistication, depth, well-being, honesty with intimacy, or combinations thereof. The invention also provides methods and kits for making a colored contact lens of the invention.
摘要翻译: 本发明涉及一种设计用于改善或增强佩戴者眼睛颜色的彩色隐形眼镜,同时给予佩戴者眼睛改善的活泼外观(或更活泼或活泼的外观)。 特别地,本发明的有色隐形眼镜可以赋予佩戴者眼睛颜色既具有复杂性,深度,幸福感,亲密感的情感维度的自然外观或其组合。 本发明还提供了用于制造本发明的有色隐形眼镜的方法和试剂盒。
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公开(公告)号:US06930196B2
公开(公告)日:2005-08-16
申请号:US09892345
申请日:2001-06-26
IPC分类号: G02C7/04 , C08G18/10 , C08G18/12 , C08G18/48 , C08G18/66 , C08G18/79 , G02B1/04 , C07C271/10 , C07C271/24 , C07C271/26 , C07D251/34
CPC分类号: C08G18/792 , C08G18/10 , C08G18/12 , C08G18/4833 , C08G18/6674 , C08G2120/00 , C08G2210/00 , G02B1/043 , C08L75/04 , C08G18/302
摘要: A prepolymer is prepared by reacting a mixture containing (a) at least one multifunctional compound, (b) at least one diisocyanate, and (c) at least one diol. The diol has a weight average molecular weight of at most 6000. The prepolymer, when reacted with an excess of water, forms a hydrogel polymer. The mixture of the prepolymer and water may be reaction molded, and used to form a contact lens.
摘要翻译: 通过使包含(a)至少一种多官能化合物,(b)至少一种二异氰酸酯和(c)至少一种二醇)的混合物反应制备预聚物。 二醇的重均分子量至多为6000.当与过量的水反应时,预聚物形成水凝胶聚合物。 预聚物和水的混合物可以被反应模制,并用于形成隐形眼镜。
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公开(公告)号:US09757525B2
公开(公告)日:2017-09-12
申请号:US13261300
申请日:2010-11-30
申请人: Richard Cronenberg , Michael Quinn , Haiming Wu
发明人: Richard Cronenberg , Michael Quinn , Haiming Wu
CPC分类号: A61M5/31548 , A61M5/24 , A61M5/2466 , A61M5/31535 , A61M5/31541 , A61M5/31543 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/3157 , A61M5/31573 , A61M5/31575 , A61M5/31585 , A61M5/31595 , A61M5/3202 , A61M5/347 , A61M2005/2407 , A61M2005/2488 , A61M2005/2492 , A61M2205/581
摘要: A medication injection pen is provided comprising a housing (218), for housing a dose set knob (220), a leadscrew (226), a driver (224), a setback member (222), and a dose stop member (228). The dose set knob (220) is rotatable with respect to said housing (218) to set a desired injection dose, and comprises at least one internal thread (291). The leadscrew (226) includes a thread element by which it is advanceable in a first direction via a corresponding thread engagement, said first direction being that which expels medication from a cartridge (36). The driver (224) is rotationally fixed to said leadscrew (226) for preventing relative rotation therebetween, said driver (224) being rotatable in a first direction to rotate and advance said leadscrew (226) in said first direction. The setback member (222) is rotationally fixed to said driver (224) for preventing relative rotation therebetween.
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公开(公告)号:US09352096B2
公开(公告)日:2016-05-31
申请号:US12859569
申请日:2010-08-19
申请人: Flora Felsovalyi , Eric Schiller , Michael Quinn
发明人: Flora Felsovalyi , Eric Schiller , Michael Quinn
CPC分类号: A61M5/31511 , A61M5/3135 , A61M5/3137 , A61M5/3148 , A61M5/31515 , A61M2005/3121 , A61M2005/3123 , A61M2005/3139 , A61M2005/31516 , A61M2005/31518
摘要: A reduced profile syringe assembly is provided that includes an overall profile that is substantially similar to a profile of a syringe barrel. The syringe assembly includes a plunger rod that is significantly disposed within the syringe barrel when filled for use, with the plunger rod adapted to be retracted from the syringe barrel during dispensing of contents of the syringe barrel.
摘要翻译: 提供了一种缩径型注射器组件,其包括基本上类似于注射器筒的轮廓的整体轮廓。 注射器组件包括柱塞杆,其在填充使用时显着地设置在注射器筒内,柱塞杆适于在分注注射器筒的内容物期间从注射器筒缩回。
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公开(公告)号:US20140163477A1
公开(公告)日:2014-06-12
申请号:US14005603
申请日:2012-03-16
申请人: Michael Quinn , Richard Cronenberg , Gautam Shetty
发明人: Michael Quinn , Richard Cronenberg , Gautam Shetty
IPC分类号: A61M5/315
CPC分类号: A61M5/31533 , A61M5/31551 , A61M5/3157 , A61M5/31585 , A61M2005/3126 , A61M2205/581 , A61M2205/583
摘要: A medication injection pen (50) includes a housing (1) and a dose set knob (2) rotatably connected to the housing (1) for setting a dose. An indicator member (200) is movable between an visible position indicating a zero position of the dose set knob (2) and a non-visible position indicating a non-zero position of the dose set knob (2). The indicator member is visible to a user in the visible position and not visible in the non-visible position. The dose set knob is in the zero position when a set dose has been completely administered. Accordingly, a visible indication is provided to a user when a set dose has been completely administered.
摘要翻译: 药物注射笔(50)包括可旋转地连接到壳体(1)的用于设定剂量的壳体(1)和剂量设定旋钮(2)。 指示器构件(200)可在指示剂量设定旋钮(2)的零位置的可见位置和指示剂量设定旋钮(2)的非零位置的不可见位置之间移动。 指示器构件对于可见位置的用户可见,并且在不可见位置中不可见。 当设定的剂量已经完全施用时,剂量设定旋钮处于零位置。 因此,当已经完全施用设定剂量时,向使用者提供可视指示。
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公开(公告)号:US20120283647A1
公开(公告)日:2012-11-08
申请号:US13261300
申请日:2010-11-30
申请人: Richard Cronenberg , Michael Quinn , Haiming Wu
发明人: Richard Cronenberg , Michael Quinn , Haiming Wu
IPC分类号: A61M5/31
CPC分类号: A61M5/31548 , A61M5/24 , A61M5/2466 , A61M5/31535 , A61M5/31541 , A61M5/31543 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/3157 , A61M5/31573 , A61M5/31575 , A61M5/31585 , A61M5/31595 , A61M5/3202 , A61M5/347 , A61M2005/2407 , A61M2005/2488 , A61M2005/2492 , A61M2205/581
摘要: A medication injection pen is provided comprising a housing (218), for housing a dose set knob (220), a leadscrew (226), a driver (224), a setback member (222), and a dose stop member (228). The dose set knob (220) is rotatable with respect to said housing (218) to set a desired injection dose, and comprises at least one internal thread (291). The leadscrew (226) includes a thread element by which it is advanceable in a first direction via a corresponding thread engagement, said first direction being that which expels medication from a cartridge (36). The driver (224) is rotationally fixed to said leadscrew (226) for preventing relative rotation therebetween, said driver (224) being rotatable in a first direction to rotate and advance said leadscrew (226) in said first direction. The setback member (222) is rotationally fixed to said driver (224) for preventing relative rotation therebetween.
摘要翻译: 提供了一种药物注射笔,其包括用于容纳剂量设定旋钮(220),丝杠(226),驱动器(224),挫折部件(222)和剂量停止部件(228)的壳体(218) 。 剂量设定旋钮(220)可相对于所述壳体(218)旋转以设定期望的喷射剂量,并且包括至少一个内螺纹(291)。 丝杠(226)包括螺纹元件,通过该螺纹元件可以通过相应的螺纹接合在第一方向前进,所述第一方向是从药筒(36)排出药物的螺纹元件。 驱动器(224)旋转地固定到所述丝杠(226)上以防止它们之间的相对旋转,所述驱动器(224)可沿第一方向旋转并使所述丝杠(226)沿所述第一方向前进。 遏制构件(222)旋转地固定到所述驱动器(224),以防止它们之间的相对旋转。
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