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公开(公告)号：US20190232295A1
公开(公告)日：2019-08-01
申请号：US16259766
申请日：2019-01-28
申请人： Yury Sherman , Michael Sherman , Ilya Alexandrov , Yehuda Buff
发明人： Yury Sherman , Michael Sherman , Ilya Alexandrov , Yehuda Buff
摘要： The present invention relates to an apparatus for substantially horizontally oscillating one or more multi-well plates containing a liquid, a solid, or a mixture thereof that operates to thoroughly disrupt solid substances in multi-well plates. The apparatus provides oscillation of plates in a horizontal direction through the use of springs and rotating mechanical components. The apparatus includes a circular rotating ring having a toothed circumference that rotates horizontally, plate holder, and a spring attached to the housing and in constant contact with the plate holder. The apparatus can be used in a cold room or placed in a refrigerator to keep the substances at low temperature and to eliminate noise when the disruptor operates.
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公开(公告)号：US09010987B2
公开(公告)日：2015-04-21
申请号：US13374939
申请日：2012-01-25
IPC分类号： B01F9/10
CPC分类号： B01F9/10
摘要： A method of mixing together liquids or liquid/solid combinations, and mixing apparatus/universal combine utilizing a vertical spinning container or vessel having a rib, or a cross rib in its bottom wall. The container is spun about a vertical axis with no wobbling component to the motion. Meshed elements are used for high shear mixing. Start/stop routines, and variable acceleration/speed values are used, to facilitate complete mixing. Use of ‘impeller’ blade stirrers is completely eliminated.
摘要翻译： 将液体或液体/固体组合物混合在一起的方法，以及利用在其底壁中具有肋的垂直纺丝容器或容器或横肋的混合装置/通用组合物。 容器围绕垂直轴线旋转，没有摆动分量。 网状元件用于高剪切混合。 使用启动/停止程序和可变加速度/速度值，以便于完全混合。 叶轮搅拌器的使用被完全消除。
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3.发明申请Automated device for homogenization and resuspension of substances, disintegration of cells, disruption of tissues and centrifugation of these media 失效用于均质化和物质再悬浮的自动装置，细胞分解，组织破坏和这些培养基的离心公开(公告)号：US20050277538A1
公开(公告)日：2005-12-15
申请号：US10866050
申请日：2004-06-14
申请人： Michael Sherman , Yury Sherman
发明人： Michael Sherman , Yury Sherman
CPC分类号： B01F9/0021 , B01F11/0266 , B01F11/0275 , B04B5/0421
摘要： A device for biological and medical tests wherein tested media placed in test tube is subjected to mixing, or homogenization, or resuspention, or disintegration, or disruption, and further centrifugation of these media, including: a rotor having a replaceable closure, driving means having substantially vertical shaft, striking means capable to engage or disengage test tubes and means for moving the rotor up and down, along a the shaft that provides engagement or disengagement of said striking means with said tubes.
摘要翻译： 用于生物和医学测试的装置，其中放置在试管中的被测试的介质经受混合，均化或再悬浮，或崩解或破坏，并进一步离心这些介质，包括：具有可替换封闭件的转子，具有 基本垂直的轴，能够接合或脱离试管的打击装置和用于沿着提供所述打击装置与所述管的接合或分离的轴上下移动转子的装置。
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4.发明授权Mixer having means for periodically mechanically striking liquid-containing tubes to induce motion of the tubes 失效混合器具有用于周期性地机械冲击含液管的装置，以引起管的运动
公开(公告)号：US5769538A
公开(公告)日：1998-06-23
申请号：US671211
申请日：1996-06-27
申请人： Michael Sherman , Yury Sherman , Katerina Sherman
发明人： Michael Sherman , Yury Sherman , Katerina Sherman
CPC分类号： B01F11/0266 , B01F11/0008 , B01F11/0275
摘要： A mixer is intended for mixing substances, resuspending pellets and disintegrating living cells, such as yeast cells. The mixer includes a tube holder and an electric motor with striking attachment(s). The main part of the holder is rigid rings coaxial with and located subsequently along the motor shaft. Each ring has a number of holes the tubes sit in. Diameters of the holes are larger then diameters of the tubes, so that there are gaps between the tubes and the rigid rings. The attachment(s) of the motor is disks with blades, affixed to the motor shaft. When the motor shaft rotates the blades strike against the tubes. Struck tubes are repelled by the rigid ring (due to a gap between the tubes and rings), get a new strike from the blades and so on. As a result, the substance inside the tube receives a turbulent motion which provides mixing, resuspending and disintegrating effects.
摘要翻译： 混合器用于混合物质，重新悬浮颗粒和分解活细胞如酵母细胞。 该混合器包括一个管保持器和一个具有醒目附件的电动马达。 支架的主要部分是与电机轴同轴并位于其后的刚性环。 每个环具有管子所在的多个孔。孔的直径大于管的直径，使得管和刚性环之间存在间隙。 电机的附件是带有叶片的盘，固定在电机轴上。 当电机轴旋转时，刀片撞击管。 撞击管被刚性环排斥（由于管和环之间的间隙），从叶片获得新的击打等等。 结果，管内的物质受到湍流运动，提供混合，重悬和分解作用。
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5.发明授权公开(公告)号：US09693658B2
公开(公告)日：2017-07-04
申请号：US14740263
申请日：2015-06-16
摘要： A hand operated device for storing, measuring, and dispensing powder or granular materials, with a simplified structure and reduced number of parts. The housing integrates a material storage container with a dispenser, comprising: special compartments and sound damper, made of elastic porous material that makes use of the device quiet; a one touch assembly and disassembly of an inner space of the device where the dispenser is located; structural elements for dispensing a predetermined volume of the material or its fraction, including a way to reduce the length of the working stroke of the dispensing mechanism; wall extensions to prevent bridges of sticky particles forming; separating walls to allow delivery a more than one material stored in one device including more than one material transporting mechanisms inside the dispenser; and structural elements providing exact measuring, and sifting or pouting of the materials.
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公开(公告)号：US20170159000A1
公开(公告)日：2017-06-08
申请号：US14958747
申请日：2015-12-03
申请人： Yury Sherman , Michael Sherman , Ilya Alexandrov
发明人： Yury Sherman , Michael Sherman , Ilya Alexandrov
IPC分类号： C12M3/06
CPC分类号： C12M27/16 , B01F11/0005 , B01F11/0008 , B01F11/0014 , B01F11/0025 , B01F11/0275 , B01F13/0052 , C12M27/14
摘要： An apparatus for substantially horizontally oscillating one or more vessels containing a liquid, a solid, or a mixture thereof that operates to thoroughly disrupt and mix solid and liquid substances in vessels, like test tubes. The apparatus provides superior mixing through oscillation of the vessels both horizontal and vertical directions through the use of one or more springs and rotating mechanical components. The apparatus includes a circular rotating ring having a toothed circumference that rotates horizontally, at least one vessel support having a compartment configured to hold the one or more vessel vessels and a spring attached to the housing and in constant contact with each of the one or more vessel supports.
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7.发明申请公开(公告)号：US20100298108A1
公开(公告)日：2010-11-25
申请号：US12804462
申请日：2010-07-22
申请人： Yury Sherman , Michael Sherman , Ian Glasgow
发明人： Yury Sherman , Michael Sherman , Ian Glasgow
CPC分类号： B01L9/06 , B01L3/5021 , B01L2300/043 , B01L2300/123 , B01L2400/0409 , B04B5/0414 , B04B2005/0435
摘要： A system including a flexible, removable tube holder that flexes to fit either a straight rack or a centrifuge rotor slot. The system provides for the elimination of manual recording of the individual tubes, and provides for the transference of the tubes from the rack to the centrifuge and back, as a group.
摘要翻译： 一种系统，包括柔性可拆卸的管座，其弯曲以适应直立架或离心机转子槽。 该系统提供了消除单独管的手动记录，并且提供了将管从机架转移到离心机和后退的组。
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公开(公告)号：US10456788B2
公开(公告)日：2019-10-29
申请号：US16259766
申请日：2019-01-28
申请人： Yury Sherman , Michael Sherman , Ilya Alexandrov , Yehuda Buff
发明人： Yury Sherman , Michael Sherman , Ilya Alexandrov , Yehuda Buff
摘要： The present invention relates to an apparatus for substantially horizontally oscillating one or more multi-well plates containing a liquid, a solid, or a mixture thereof that operates to thoroughly disrupt solid substances in multi-well plates. The apparatus provides oscillation of plates in a horizontal direction through the use of springs and rotating mechanical components. The apparatus includes a circular rotating ring having a toothed circumference that rotates horizontally, plate holder, and a spring attached to the housing and in constant contact with the plate holder. The apparatus can be used in a cold room or placed in a refrigerator to keep the substances at low temperature and to eliminate noise when the disruptor operates.
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公开(公告)号：US09695392B2
公开(公告)日：2017-07-04
申请号：US14958747
申请日：2015-12-03
申请人： Yury Sherman , Michael Sherman , Ilya Alexandrov
发明人： Yury Sherman , Michael Sherman , Ilya Alexandrov
CPC分类号： C12M27/16 , B01F11/0005 , B01F11/0008 , B01F11/0014 , B01F11/0025 , B01F11/0275 , B01F13/0052 , C12M27/14
摘要： An apparatus for substantially horizontally oscillating one or more vessels containing a liquid, a solid, or a mixture thereof that operates to thoroughly disrupt and mix solid and liquid substances in vessels, like test tubes. The apparatus provides superior mixing through oscillation of the vessels both horizontal and vertical directions through the use of one or more springs and rotating mechanical components. The apparatus includes a circular rotating ring having a toothed circumference that rotates horizontally, at least one vessel support having a compartment configured to hold the one or more vessel vessels and a spring attached to the housing and in constant contact with each of the one or more vessel supports.
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10.发明申请Device and Industrial Package for Storing, Measuring and Dispensing Powder and Granular Substances 审中-公开用于储存，测量和分配粉末和颗粒物质的设备和工业包装公开(公告)号：US20160367054A1
公开(公告)日：2016-12-22
申请号：US14740263
申请日：2015-06-16
摘要： The invention is directed to a hand operated device for storing, measuring and dispensing of powder or granular materials, with effectively simplified structure and reduced number of parts, having a solid housing integrating material storage container with stationer parts of a dispenser, comprising: special compartments and sound damper, made of elastic porous material that makes work of the device quite and thus acceptable for users; a means for one touch assembly and disassembly of an inner space of the device where a dispenser is located; structural elements for dispensing a predetermined volume of the material or its fraction, including stopping means for reduction of length of working stroke of the dispensing mechanism; a means making the device reliable when it is used with materials including sticky particles; a means providing the device configured to delivery more then one material stored in one device, including more then one material transporting mechanisms inside the dispenser; and structural elements providing exact measuring, and sifting or pouring of the materials.
摘要翻译： 本发明涉及一种用于存储，测量和分配粉末或颗粒材料的手动装置，具有有效简化的结构和减少的部件数量，具有固体壳体，整体材料储存容器具有分配器的台架部件，包括：特殊隔室 并且由弹性多孔材料制成的阻尼器，使得该装置的工作非常可靠，因此对于用户而言是可接受的; 用于一次性组装和拆卸所述装置的内部空间的装置，其中分配器位于所述内部空间中; 用于分配预定体积的材料或其部分的结构元件，包括用于减小分配机构的工作行程长度的止动装置; 当使用包括粘性颗粒的材料时，使设备可靠; 提供装置，其被配置为递送多于一个存储在一个装置中的材料，包括在分配器内的多于一个材料输送机构; 以及提供精确测量，筛选或倾倒材料的结构元件。
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