公开(公告)号：US07176299B2

公开(公告)日：2007-02-13

申请号：US11166905

申请日：2005-06-23

申请人： Michael Terence Black ,  Martin Karl Russell Burnham ,  Jason Craig Fedon ,  John Edward Hodgson ,  David Justin Charles Knowles ,  Michael Arthur Lonetto ,  Richard Oakley Nicholas ,  Leslie Marie Palmer ,  Julie M. Pratt ,  Raymond Winfield Reichard ,  Martin Rosenberg ,  Christopher Michael Traini ,  Judith M. Ward ,  Richard Lloyd Warren

发明人： Michael Terence Black ,  Martin Karl Russell Burnham ,  Jason Craig Fedon ,  John Edward Hodgson ,  David Justin Charles Knowles ,  Michael Arthur Lonetto ,  Richard Oakley Nicholas ,  Leslie Marie Palmer ,  Julie M. Pratt ,  Raymond Winfield Reichard ,  Martin Rosenberg ,  Christopher Michael Traini ,  Judith M. Ward ,  Richard Lloyd Warren

IPC分类号： C07H21/04 ,  C12N1/20 ,  C12N15/00

CPC分类号： C12N9/0036 ,  A61K38/00 ,  A61K39/00 ,  C07K14/31 ,  C07K16/1275 ,  C07K2319/00 ,  C12N9/78 ,  C12N15/52 ,  C12Q1/689 ,  C12Q2600/158 ,  C12Y105/0103 ,  C12Y305/04025

摘要： This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.

摘要翻译： 本发明涉及新鉴定的葡萄球菌多核苷酸，由这种多核苷酸编码的多肽，这种多核苷酸和多肽的用途，以及这些多核苷酸和多肽的产生以及用多核苷酸转化的重组宿主细胞。 本发明还涉及抑制这些多核苷酸或多肽的生物合成或作用以及这种抑制剂在治疗中的用途。