公开(公告)号：US20120281899A1

公开(公告)日：2012-11-08

申请号：US13494303

申请日：2012-06-12

Applicant: Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

Inventor： Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

IPC: G01J3/45 ,  G06K9/36

CPC classification number: A61B5/0066 ,  A61B5/0073 ,  A61B5/7257 ,  G01B9/02044 ,  G01B9/02083 ,  G01B9/02091 ,  G01N21/4795

Abstract: An apparatus and method process optical coherence tomography (OCT) imaging data from a sample. The method includes using a magnitude spectrum and an estimated phase term of a complex spatial Fourier transform of a complex intermediate function to generate an estimated complex spatial Fourier transform. The method further includes calculating an inverse Fourier transform of the estimated complex spatial Fourier transform and calculating an estimated intermediate function by applying at least one constraint to the inverse Fourier transform. The apparatus includes a partially reflective element configured to reflect a first portion of light and to allow a second portion of light to propagate through the partially reflective element and to reflect from the sample. The apparatus further includes a detector that measures the OCT power spectrum in response to the first and second portions of light.

Abstract translation: 来自样品的装置和方法处理光学相干断层扫描（OCT）成像数据。 该方法包括使用复数中间函数的复数空间傅里叶变换的幅度谱和估计相位项来生成估计的复数空间傅里叶变换。 该方法还包括通过对傅立叶逆变换应用至少一个约束来计算所估计的复数空间傅里叶变换的逆傅立叶变换并计算估计的中间函数。 该装置包括部分反射元件，其被配置为反射第一部分光并且允许光的第二部分传播通过部分反射元件并从样品反射。 该装置还包括响应于第一和第二部分光量测量OCT功率谱的检测器。

公开(公告)号：US20100067827A1

公开(公告)日：2010-03-18

申请号：US12623322

申请日：2009-11-20

Applicant: Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

Inventor： Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

IPC: G06K9/36

CPC classification number: G06E3/003 ,  G01J3/45 ,  G01J11/00

Abstract: A method utilizes an optical image processing system. The method includes providing a measured magnitude of the Fourier transform of a complex transmission function of an object or optical image. The method further includes providing an estimated phase term of the Fourier transform of the complex transmission function. The method further includes multiplying the measured magnitude and the estimated phase term to generate an estimated Fourier transform of the complex transmission function. The method further includes calculating an inverse Fourier transform of the estimated Fourier transform, wherein the inverse Fourier transform is a spatial function. The method further includes calculating an estimated complex transmission function by applying at least one constraint to the inverse Fourier transform.

Abstract translation: 一种方法利用光学图像处理系统。 该方法包括提供物体或光学图像的复数传输函数的傅里叶变换的测量幅度。 该方法还包括提供复传输函数的傅立叶变换的估计相位项。 该方法还包括将测量的幅度和估计的相位项相乘以产生复数传输函数的估计傅里叶变换。 该方法还包括计算傅立叶逆变换的傅立叶逆变换，其中逆傅里叶变换是空间函数。 该方法还包括通过对傅里叶逆变换应用至少一个约束来计算估计的复传输函数。

公开(公告)号：US20080204726A1

公开(公告)日：2008-08-28

申请号：US12116871

申请日：2008-05-07

Applicant: Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

Inventor： Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

IPC: G01N21/00

CPC classification number: G02B6/0208 ,  G01M11/3145 ,  G01M11/3172 ,  G02B2006/02166

Abstract: An apparatus characterizes at least one fiber Bragg grating. The apparatus includes a laser pulse source, an optical spectrum analyzer, and multiple optical paths. A first optical path includes a pulse stretcher and an attenuator. A second optical path optically coupled to the first optical path includes a mirror. A third optical path optically coupled to the first optical path includes a first fiber Bragg grating. A fourth optical path is optically coupled to the second optical path, the third optical path, and the optical spectrum analyzer. A fifth optical path optically coupled to the laser pulse source and the optical spectrum analyzer includes a delay line.

Abstract translation: 一种装置表征至少一个光纤布拉格光栅。 该装置包括激光脉冲源，光谱分析仪和多个光路。 第一光路包括脉冲展宽器和衰减器。 光耦合到第一光路的第二光路包括反射镜。 光学耦合到第一光路的第三光路包括第一光纤布拉格光栅。 第四光路光耦合到第二光路，第三光路和光谱分析仪。 光耦合到激光脉冲源和光谱分析仪的第五光路包括延迟线。

公开(公告)号：US20090207414A1

公开(公告)日：2009-08-20

申请号：US12372225

申请日：2009-02-17

Applicant: Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

Inventor： Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

IPC: G01B9/02 ,  G01B11/02 ,  G01J3/45

CPC classification number: A61B5/0066 ,  A61B5/0073 ,  A61B5/7257 ,  G01B9/02044 ,  G01B9/02083 ,  G01B9/02091 ,  G01N21/4795

Abstract: An apparatus is provided for measuring a frequency-domain optical coherence tomography power spectrum from a sample. The apparatus includes a broadband light source, an optical spectrum analyzer, and a partially reflective element optically coupled to the light source, to the optical spectrum analyzer, and to the sample. A first portion of light from the light source is reflected by the partially reflective element and propagates to the optical spectrum analyzer. A second portion of light from the light source propagating through the partially reflective element, impinging the sample, reflecting from the sample, and propagating to the optical spectrum analyzer.

Abstract translation: 提供了一种用于从样本测量频域光学相干断层摄影功率谱的装置。 该装置包括宽带光源，光谱分析仪和与光源光耦合到光谱分析仪和样品的部分反射元件。 来自光源的光的第一部分被部分反射元件反射并传播到光谱分析仪。 来自光源的光的第二部分传播通过部分反射元件，撞击样品，从样品反射并传播到光谱分析仪。

公开(公告)号：US20090207401A1

公开(公告)日：2009-08-20

申请号：US12343449

申请日：2008-12-23

Applicant: Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

Inventor： Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

IPC: G01N21/00

CPC classification number: G02B6/0208 ,  G01M11/3145 ,  G01M11/3172 ,  G02B2006/02166

Abstract: An apparatus characterizes at least one fiber Bragg grating. The apparatus includes a laser pulse source, an optical spectrum analyzer, and multiple optical paths. A first optical path includes a pulse stretcher and an attenuator. A second optical path optically coupled to the first optical path includes a mirror. A third optical path optically coupled to the first optical path includes a first fiber Bragg grating. A fourth optical path is optically coupled to the second optical path, the third optical path, and the optical spectrum analyzer. A fifth optical path optically coupled to the laser pulse source and the optical spectrum analyzer includes a delay line.

Abstract translation: 一种装置表征至少一个光纤布拉格光栅。 该装置包括激光脉冲源，光谱分析仪和多个光路。 第一光路包括脉冲展宽器和衰减器。 光耦合到第一光路的第二光路包括反射镜。 光学耦合到第一光路的第三光路包括第一光纤布拉格光栅。 第四光路光耦合到第二光路，第三光路和光谱分析仪。 光耦合到激光脉冲源和光谱分析仪的第五光路包括延迟线。

公开(公告)号：US20110273712A1

公开(公告)日：2011-11-10

申请号：US13187930

申请日：2011-07-21

Applicant: Michel J.F. Digonnet ,  Aydogan Ozcan

Inventor： Michel J.F. Digonnet ,  Aydogan Ozcan

IPC: G01N21/59 ,  H01S3/08 ,  G02B6/00

CPC classification number: G02B6/02328 ,  G02B6/02052 ,  G02B6/02304 ,  G02B6/02347 ,  G02B6/02376 ,  G02B6/2552

Abstract: An optical device and methods of using an optical device are provided. The optical device includes a hollow-core fiber including a first portion and a second portion. The first portion includes a hollow core having a first diameter. The second portion includes a hollow core having a second diameter smaller than the first diameter. The difference between the first diameter and the second diameter is less than 10% of the first diameter.

Abstract translation: 提供了光学装置和使用光学装置的方法。 光学装置包括中空纤维，其包括第一部分和第二部分。 第一部分包括具有第一直径的中空芯。 第二部分包括具有小于第一直径的第二直径的中空芯。 第一直径和第二直径之间的差小于第一直径的10％。

公开(公告)号：US20100296093A1

公开(公告)日：2010-11-25

申请号：US12777905

申请日：2010-05-11

Applicant: Michel J.F. Digonnet ,  Aydogan Ozcan

Inventor： Michel J.F. Digonnet ,  Aydogan Ozcan

IPC: G01N21/00 ,  G02B6/26 ,  H01S3/30 ,  C03B37/025

CPC classification number: G02B6/02328 ,  G02B6/02052 ,  G02B6/02304 ,  G02B6/02347 ,  G02B6/02376 ,  G02B6/2552

Abstract: An optical device and methods of using an optical device are provided. The optical device includes a hollow-core fiber including a first portion and a second portion. The first portion includes a hollow core having a first diameter. The second portion includes a hollow core having a second diameter smaller than the first diameter. The difference between the first diameter and the second diameter is less than 10% of the first diameter.

Abstract translation: 提供了光学装置和使用光学装置的方法。 光学装置包括中空纤维，其包括第一部分和第二部分。 第一部分包括具有第一直径的中空芯。 第二部分包括具有小于第一直径的第二直径的中空芯。 第一直径和第二直径之间的差小于第一直径的10％。

公开(公告)号：US07050169B2

公开(公告)日：2006-05-23

申请号：US10645331

申请日：2003-08-21

Applicant: Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

Inventor： Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

IPC: G01N21/59

CPC classification number: G01N21/21 ,  G01J11/00 ,  G01N21/4788 ,  G01N21/636 ,  G01N2021/4723 ,  G01N2021/4735

Abstract: A method for measuring a physical function forms a symmetric composite function by combining the physical function with a reference function. The method obtains a Fourier transform of the symmetric composite function. The method calculates an inverse Fourier transform of the obtained Fourier transform, wherein the calculated inverse Fourier transform provides information regarding the physical function. The physical function can be a nonlinearity profile of a sample with at least one sample surface. The physical function can alternatively by a sample temporal waveform of a sample optical pulse.

公开(公告)号：US20120099803A1

公开(公告)日：2012-04-26

申请号：US13290982

申请日：2011-11-07

Applicant: Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

Inventor： Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

IPC: G06K9/36

CPC classification number: G06E3/003 ,  G01J3/45 ,  G01J11/00

Abstract: A method utilizes an optical image processing system. The method includes calculating a product of (i) a measured magnitude of a Fourier transform of a complex transmission function of an object or optical image and (ii) an estimated phase term of the Fourier transform of the complex transmission function. The method further includes calculating an inverse Fourier transform of the product, wherein the inverse Fourier transform is a spatial function. The method further includes calculating an estimated complex transmission function by applying at least one constraint to the inverse Fourier transform.

Abstract translation: 一种方法利用光学图像处理系统。 该方法包括：计算（i）物体或光学图像的复数传播函数的傅里叶变换的测量幅度和（ii）复数传递函数的傅立叶变换的估计相位项的乘积。 该方法还包括计算乘积的逆傅里叶变换，其中逆傅立叶变换是空间函数。 该方法还包括通过对傅里叶逆变换应用至少一个约束来计算估计的复传输函数。

公开(公告)号：US20110317167A1

公开(公告)日：2011-12-29

申请号：US13224555

申请日：2011-09-02

Applicant: Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

Inventor： Aydogan Ozcan ,  Michel J.F. Digonnet ,  Gordon S. Kino

IPC: G01B9/02

CPC classification number: A61B5/0066 ,  A61B5/0073 ,  A61B5/7257 ,  G01B9/02044 ,  G01B9/02083 ,  G01B9/02091 ,  G01N21/4795

Abstract: An apparatus is provided for measuring a frequency-domain optical coherence tomography power spectrum from a sample. The apparatus includes a partially reflective element configured to be optically coupled to a light source and to the sample. A first portion of light from the light source is configured to be reflected by the partially reflective element. A second portion of light from the light source is configured to propagate through the partially reflective element, to impinge the sample, and to reflect from the sample. The apparatus is configured to receive the first and second portions of light and to measure the frequency-domain optical coherence tomography power spectrum in response to the first portion of light and the second portion of light.

Abstract translation: 提供了一种用于从样本测量频域光学相干断层摄影功率谱的装置。 该装置包括被配置为光耦合到光源和样品的部分反射元件。 来自光源的第一部分光被构造成被部分反射元件反射。 来自光源的第二部分光被配置成传播通过部分反射元件，以撞击样品并从样品反射。 该装置被配置为接收第一和第二部分光并且响应于第一部分光和第二部分光来测量频域光学相干断层摄影功率谱。