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公开(公告)号：US20090076477A1
公开(公告)日：2009-03-19
申请号：US12208878
申请日：2008-09-11
申请人： Michel Schneider , Christophe Golay , Laurent Jakob , Jean Brochot , Feng Yan , Christian Mathieu
发明人： Michel Schneider , Christophe Golay , Laurent Jakob , Jean Brochot , Feng Yan , Christian Mathieu
CPC分类号： A61M5/1456 , A61B2017/22008 , A61B2090/3925 , A61B2090/3933 , A61M5/007 , A61M2205/6072 , B01F9/0016 , B01F11/0002 , B01F2003/0035
摘要： A power assisted method and injector device for controllably delivering to patients a dispersion medicament or diagnostically active agent, the homogeneity of which is preserved throughout delivery. Diagnostically active agents disclosed are gas microbubble suspensions useful in ultrasonic diagnostic imaging and liposomal formulations in which liposome vesicles are loaded with iodinated compounds.
摘要翻译： 一种功率辅助方法和注射器装置，用于可控地向患者输送分散药物或诊断活性剂，其均匀性在整个递送期间保留。 所公开的诊断活性剂是用于超声诊断成像的气体微泡悬浮液和其中脂质体囊泡装载碘化化合物的脂质体制剂。
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公开(公告)号：US20120265065A1
公开(公告)日：2012-10-18
申请号：US13467301
申请日：2012-05-09
申请人： Michel Schneider , Christophe Golay , Laurent Jakob , Jean Brochot , Feng Yan , Christian Mathieu
发明人： Michel Schneider , Christophe Golay , Laurent Jakob , Jean Brochot , Feng Yan , Christian Mathieu
CPC分类号： A61M5/1456 , A61B2017/22008 , A61B2090/3925 , A61B2090/3933 , A61M5/007 , A61M2205/6072 , B01F9/0016 , B01F11/0002 , B01F2003/0035
摘要： A power assisted method and injector device for controllably delivering to patients a dispersion medicament or diagnostically active agent, the homogeneity of which is preserved throughout delivery. Diagnostically active agents disclosed are gas microbubble suspensions useful in ultrasonic diagnostic imaging and liposomal formulations in which liposome vesicles are loaded with iodinated compounds.
摘要翻译： 一种功率辅助方法和注射器装置，用于可控地向患者输送分散药物或诊断活性剂，其均匀性在整个递送期间保留。 所公开的诊断活性剂是用于超声诊断成像的气体微泡悬浮液和其中脂质体囊泡装载碘化化合物的脂质体制剂。
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公开(公告)号：US06726650B2
公开(公告)日：2004-04-27
申请号：US09204067
申请日：1998-12-03
申请人： Michel Schneider , Christophe Golay , Laurent Jakob , Jean Brochot , Feng Yan , Christian Mathieu
发明人： Michel Schneider , Christophe Golay , Laurent Jakob , Jean Brochot , Feng Yan , Christian Mathieu
IPC分类号： A61M3700
CPC分类号： A61M5/1456 , A61B2017/22008 , A61B2090/3925 , A61B2090/3933 , A61M5/007 , A61M2205/6072 , B01F9/0016 , B01F11/0002 , B01F2003/0035
摘要： A power assisted method and injector device for controllably delivering to patients a dispersion medicament or diagnostically active agent, the homogeneity of which is preserved throughout delivery. Diagnostically active agents disclosed are gas microbubble suspensions useful in ultrasonic diagnostic imaging and liposomal formulations in which liposome vesicles are loaded with iodinated compounds.
摘要翻译： 一种功率辅助方法和注射器装置，用于可控地向患者输送分散药物或诊断活性剂，其均匀性在整个递送期间保留。 所公开的诊断活性剂是用于超声诊断成像的气体微泡悬浮液和其中脂质体囊泡装载碘化化合物的脂质体制剂。
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公开(公告)号：US20110245663A1
公开(公告)日：2011-10-06
申请号：US13010044
申请日：2011-01-20
申请人： Michel Schneider , Christophe Golay , Laurent Jakob , Jean Brochot , Feng Yan , Christian Mathieu
发明人： Michel Schneider , Christophe Golay , Laurent Jakob , Jean Brochot , Feng Yan , Christian Mathieu
IPC分类号： A61B6/00
CPC分类号： A61M5/1456 , A61B2017/22008 , A61B2090/3925 , A61B2090/3933 , A61M5/007 , A61M2205/6072 , B01F9/0016 , B01F11/0002 , B01F2003/0035
摘要： A power assisted method and injector device for controllably delivering to patients a dispersion medicament or diagnostically active agent, the homogeneity of which is preserved throughout delivery. Diagnostically active agents disclosed are gas microbubble suspensions useful in ultrasonic diagnostic imaging and liposomal formulations in which liposome vesicles are loaded with iodinated compounds.
摘要翻译： 一种功率辅助方法和注射器装置，用于向患者可控地递送分散药物或诊断活性剂，其均匀性在整个递送期间保留。 所公开的诊断活性剂是用于超声诊断成像的气体微泡悬浮液和其中脂质体囊泡装载碘化化合物的脂质体制剂。
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公开(公告)号：US07534239B1
公开(公告)日：2009-05-19
申请号：US09576422
申请日：2000-05-22
申请人： Michel Schneider , Laurent Jakob , Christophe Golay , Jean Brochot , Feng Yan
发明人： Michel Schneider , Laurent Jakob , Christophe Golay , Jean Brochot , Feng Yan
IPC分类号： A61M31/00
CPC分类号： A61M5/1456 , A61B2017/22008 , A61B2090/3925 , A61B2090/3933 , A61M5/007 , A61M2205/6072 , B01F9/0016 , B01F11/0002 , B01F2003/0035
摘要： A power assisted method and injector device for controllably delivering to patients a dispersion medicament or diagnostically active agent, the homogeneity of which is preserved throughout delivery. Diagnostically active agents disclosed are gas microbubble suspensions useful in ultrasonic diagnostic imaging and liposomal formulations in which liposome vesicles are loaded with iodinated compounds.
摘要翻译： 一种功率辅助方法和注射器装置，用于可控地向患者输送分散药物或诊断活性剂，其均匀性在整个递送期间保留。 所公开的诊断活性剂是用于超声诊断成像的气体微泡悬浮液和其中脂质体囊泡装载碘化化合物的脂质体制剂。
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公开(公告)号：US20090159485A1
公开(公告)日：2009-06-25
申请号：US12086310
申请日：2006-12-05
申请人： Laurent Jakob , Frederic Rivas
发明人： Laurent Jakob , Frederic Rivas
CPC分类号： A61M5/162 , A61J1/201 , A61J1/2075 , A61J1/2082 , A61J1/2089 , A61J1/2096 , A61M2005/1623
摘要： A kit comprising a medical dispensing container (402), such as a vial for diagnostic agents, and a liquid transfer device (401) to be used to transfer a liquid into or from said dispensing container. The transfer device allows substantially limiting the gaseous exchange between the inside of a vial and the external ambient, when the device is connected to the vial in steady state conditions.
摘要翻译： 一种药盒，包括用于诊断剂的药物分配容器（402），以及用于将液体转移到所述分配容器中的液体转移装置（401）。 当设备在稳态条件下连接到小瓶时，转移装置允许基本上限制小瓶内部和外部环境之间的气体交换。
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公开(公告)号：US09238103B2
公开(公告)日：2016-01-19
申请号：US12086310
申请日：2006-12-05
申请人： Laurent Jakob , Frederic Rivas
发明人： Laurent Jakob , Frederic Rivas
CPC分类号： A61M5/162 , A61J1/201 , A61J1/2075 , A61J1/2082 , A61J1/2089 , A61J1/2096 , A61M2005/1623
摘要： A kit comprising a medical dispensing container (402), such as a vial for diagnostic agents, and a liquid transfer device (401) to be used to transfer a liquid into or from said dispensing container. The transfer device allows substantially limiting the gaseous exchange between the inside of a vial and the external ambient, when the device is connected to the vial in steady state conditions.
摘要翻译： 一种药盒，包括用于诊断剂的药物分配容器（402），以及用于将液体转移到所述分配容器中的液体转移装置（401）。 当设备在稳态条件下连接到小瓶时，转移装置允许基本上限制小瓶内部和外部环境之间的气体交换。
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公开(公告)号：US20110245664A1
公开(公告)日：2011-10-06
申请号：US13133572
申请日：2009-12-15
申请人： Laurent Jakob , Frederic Rivas
发明人： Laurent Jakob , Frederic Rivas
CPC分类号： A61M5/1782 , A61M5/162 , A61M5/204 , A61M5/31553 , A61M2005/3114
摘要： A device for administering a liquid preparation comprising a pharmaceutical agent, particularly a contrast agent, in the form of a bolus. The device comprises in particular a core cylinder and an external cylinder, the core cylinder comprising a conduit (107) and a cylindrical reservoir (108) cooperating with a respective plunger (109), wherein the plunger is modified in order to operatively engage with guiding means (300) provided on the external cylinder.
摘要翻译： 一种用于施用包含药丸剂，特别是造影剂的药剂的液体制剂的装置。 该装置特别包括一个芯筒和一个外筒，该芯筒包括与相应的柱塞（109）配合的导管（107）和圆柱形容器（108），其中柱塞被改型以与引导 设在外筒上的装置（300）。
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公开(公告)号：US20080045919A1
公开(公告)日：2008-02-21
申请号：US11794024
申请日：2005-12-20
申请人： Laurent Jakob , Frederic Rivas
发明人： Laurent Jakob , Frederic Rivas
IPC分类号： A61B19/00
CPC分类号： A61M5/162 , A61M2005/1623
摘要： Liquid transfer device to be used to transfer a liquid into or from a dispensing container, particularly a medical dispensing container like a vial for diagnostic agents and kit comprising a vial, a syringe and a device of the aforementioned type. The transfer device comprises a valve which substantially limits the gaseous exchange between the inside of a vial and the external ambient, when the device is connected to the vial in steady state conditions.
摘要翻译： 用于将液体输送到分配容器中的液体转移装置，特别是用于诊断剂的小瓶的药物分配容器以及包括小瓶，注射器和上述类型的装置的试剂盒。 当装置在稳态条件下连接到小瓶时，转移装置包括基本上限制小瓶内部和外部环境之间的气体交换的阀。
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公开(公告)号：US08394070B2
公开(公告)日：2013-03-12
申请号：US13133572
申请日：2009-12-15
申请人： Laurent Jakob , Frederic Rivas
发明人： Laurent Jakob , Frederic Rivas
CPC分类号： A61M5/1782 , A61M5/162 , A61M5/204 , A61M5/31553 , A61M2005/3114
摘要： A device for administering a liquid preparation comprising a pharmaceutical agent, particularly a contrast agent, in the form of a bolus. The device comprises in particular a core cylinder and an external cylinder, the core cylinder comprising a conduit (107) and a cylindrical reservoir (108) cooperating with a respective plunger (109), wherein the plunger is modified in order to operatively engage with guiding means (300) provided on the external cylinder.
摘要翻译： 一种用于施用包含药丸剂，特别是造影剂的药剂的液体制剂的装置。 该装置特别包括一个芯筒和一个外筒，该芯筒包括与相应的柱塞（109）配合的导管（107）和圆柱形容器（108），其中柱塞被改型以与引导 设在外筒上的装置（300）。
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